{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:59:15Z","timestamp":1790773155666,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012397","name":"Army Medical University","doi-asserted-by":"publisher","award":["2025XQN47"],"award-info":[{"award-number":["2025XQN47"]}],"id":[{"id":"10.13039\/501100012397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31671238"],"award-info":[{"award-number":["31671238"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32071167"],"award-info":[{"award-number":["32071167"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ibroneuroscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.neuroscience.2026.08.030","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T07:08:45Z","timestamp":1787209725000},"page":"177-188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Hypoxic preconditioning alleviates hypoxia-induced anapyrexia by attenuating cerebral lactate elevation"],"prefix":"10.1016","volume":"615","author":[{"given":"Tian","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junxia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zejun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabo","family":"Shan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6127-5687","authenticated-orcid":false,"given":"Qing-Yuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neuroscience.2026.08.030_b0005","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.neulet.2018.10.046","article-title":"The neuroscience of adaptive thermoregulation","volume":"692","author":"Angilletta","year":"2019","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1023\/A:1014806723147","article-title":"Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system","volume":"27","author":"Bergersen","year":"2002","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0015","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1749-6632.1998.tb08319.x","article-title":"Hypothalamic neurons. Mechanisms of sensitivity to temperature","volume":"856","author":"Boulant","year":"1998","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"Suppl 5","key":"10.1016\/j.neuroscience.2026.08.030_b0020","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1086\/317521","article-title":"Role of the preoptic-anterior hypothalamus in thermoregulation and fever","volume":"31","author":"Boulant","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0025","doi-asserted-by":"crossref","first-page":"5979","DOI":"10.1038\/s41467-024-50166-7","article-title":"Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture","volume":"15","author":"Braga","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0035","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S1095-6433(99)00032-X","article-title":"Central thermoregulatory effects of lactate in the toad bufo paracnemis","volume":"122","author":"Branco","year":"1999","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0030","doi-asserted-by":"crossref","first-page":"948","DOI":"10.2741\/e154","article-title":"Gaseous neurotransmitters and their role in anapyrexia","volume":"2","author":"Branco","year":"2010","journal-title":"Front. Biosci. (Elite Ed.)"},{"issue":"Pt 3","key":"10.1016\/j.neuroscience.2026.08.030_b0040","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/bj3410529","article-title":"Characterization of the high-affinity monocarboxylate transporter MCT2 in xenopus laevis oocytes","volume":"341","author":"Br\u00f6er","year":"1999","journal-title":"Biochem. J"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0045","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.cmet.2018.03.008","article-title":"The science and translation of lactate shuttle theory","volume":"27","author":"Brooks","year":"2018","journal-title":"Cell Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0050","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/0091-3057(76)90216-1","article-title":"Anteroventral third ventricle site of action for angiotensin induced thirst","volume":"4","author":"Buggy","year":"1976","journal-title":"Pharmacol. Biochem. Behav"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0055","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.1113\/JP285230","article-title":"Mechanisms underlying the health benefits of intermittent hypoxia conditioning","volume":"602","author":"Burtscher","year":"2024","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0060","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.tem.2022.07.004","article-title":"Understanding lactate sensing and signalling","volume":"33","author":"Certo","year":"2022","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0070","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1007\/s11325-019-01947-8","article-title":"Astragaloside IV ameliorates intermittent hypoxia-induced inflammatory dysfunction by suppressing MAPK\/NF-\u03bab signalling pathways in beas-2b cells","volume":"24","author":"Chen","year":"2020","journal-title":"Sleep & Breathing = Schlaf & Atmung"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0065","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/s41422-024-01064-6","article-title":"Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation","volume":"35","author":"Chen","year":"2025","journal-title":"Cell Res."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0075","first-page":"304","article-title":"Humans in hypoxia: a conspiracy of maladaptation?!","volume":"30","author":"Dempsey","year":"2015","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0080","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.cmet.2017.06.021","article-title":"Neuronal stimulation triggers neuronal glycolysis and not lactate uptake","volume":"26","author":"D\u00edaz-Garc\u00eda","year":"2017","journal-title":"Cell Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0085","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1089\/ham.2014.1098","article-title":"Acute normobaric hypoxia reduces body temperature in humans","volume":"16","author":"Dipasquale","year":"2015","journal-title":"High Alt. Med. Biol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0090","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/329441a0","article-title":"Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus","volume":"329","author":"Dragunow","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0095","doi-asserted-by":"crossref","first-page":"9725","DOI":"10.3390\/ijerph18189725","article-title":"The effect of cold exposure on cognitive performance in healthy adults: a systematic review","volume":"18","author":"Falla","year":"2021","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0100","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1749-6632.2009.05028.x","article-title":"The neuronal control of hypoxic ventilation: erythropoietin and sexual dimorphism","volume":"1177","author":"Gassmann","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0105","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1113\/JP278917","article-title":"Global REACH 2018: the influence of acute and chronic hypoxia on cerebral haemodynamics and related functional outcomes during cold and heat stress","volume":"598","author":"Gibbons","year":"2020","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0110","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1177\/0271678X231185507","article-title":"Intermittent hypoxia protects against hypoxic-ischemic brain damage by inducing functional angiogenesis","volume":"43","author":"Guan","year":"2023","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0115","first-page":"370","article-title":"Effects of hypoxia on cerebral microvascular angiogenesis: benefits or damages?","volume":"14","author":"Guan","year":"2023","journal-title":"Aging Dis."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0120","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.709825","article-title":"Nitric oxide synthase neurons in the preoptic hypothalamus are NREM and REM sleep-active and lower body temperature","volume":"15","author":"Harding","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0125","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1242\/jeb.096537","article-title":"Molecular basis of chill resistance adaptations in poikilothermic animals","volume":"217","author":"Hayward","year":"2014","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0130","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/328632a0","article-title":"Induction of c-fos-like protein in spinal cord neurons following sensory stimulation","volume":"328","author":"Hunt","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0135","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1177\/0271678X15611912","article-title":"Hemichannel-mediated release of lactate","volume":"36","author":"Karagiannis","year":"2016","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107862","article-title":"Transport function, regulation, and biology of human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4)","volume":"226","author":"Kobayashi","year":"2021","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0145","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/mus.25960","article-title":"Comparing excitability at 37 degrees c versus at 20 degrees c: differences between motor and sensory axons","volume":"57","author":"Kovalchuk","year":"2018","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0150","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.neuroscience.2011.11.030","article-title":"Hydrogen sulfide as a cryogenic mediator of hypoxia-induced anapyrexia","volume":"201","author":"Kwiatkoski","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0155","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1093\/cercor\/bht136","article-title":"Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism","volume":"24","author":"Lauritzen","year":"2014","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0160","doi-asserted-by":"crossref","first-page":"R822","DOI":"10.1152\/ajpregu.00094.2022","article-title":"Activation of brain lactate receptor GPR81 aggravates exercise-induced central fatigue","volume":"323","author":"Li","year":"2022","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0165","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/cns.13642","article-title":"Neuroprotective effects and mechanisms of ischemic\/hypoxic preconditioning on neurological diseases","volume":"27","author":"Liu","year":"2021","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0170","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.cmet.2015.10.010","article-title":"In vivo evidence for a lactate gradient from astrocytes to neurons","volume":"23","author":"Machler","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0175","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nrn.2018.19","article-title":"Lactate in the brain: from metabolic end-product to signalling molecule","volume":"19","author":"Magistretti","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0180","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1038\/s41598-024-53208-8","article-title":"The temperature sensitivity of motor units in rat soleus","volume":"14","author":"Malak","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0185","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1113\/EP088256","article-title":"The effects of local forearm heating and cooling on motor unit properties during submaximal contractions","volume":"106","author":"Mallette","year":"2021","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0190","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1073\/pnas.1914112117","article-title":"Hypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignment","volume":"117","author":"Manella","year":"2020","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0195","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/(SICI)1097-4547(19990715)57:2<255::AID-JNR11>3.0.CO;2-6","article-title":"Astrocytes respond to hypoxia by increasing glycolytic capacity","volume":"57","author":"Marrif","year":"1999","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.114158","article-title":"Inhibition of type 4 cAMP-phosphodiesterases (PDE4s) in mice induces hypothermia via effects on behavioral and central autonomous thermoregulation","volume":"180","author":"Mcdonough","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0205","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2204619119","article-title":"Whole-brain neuronal MCT2 lactate transporter expression links metabolism to human brain structure and function","volume":"119","author":"Medel","year":"2022","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0210","doi-asserted-by":"crossref","first-page":"R922","DOI":"10.1152\/ajpregu.00059.2008","article-title":"Neonatal caffeine induces sex-specific developmental plasticity of the hypoxic respiratory chemoreflex in adult rats","volume":"295","author":"Montandon","year":"2008","journal-title":"Am. J. Physiology. Regulatory, Integrative and Comparative Physiology"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0215","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1126\/science.3037702","article-title":"Mapping patterns of c-fos expression in the central nervous system after seizure","volume":"237","author":"Morgan","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0220","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.autneu.2016.02.010","article-title":"Central neural control of thermoregulation and brown adipose tissue","volume":"196","author":"Morrison","year":"2016","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0225","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1146\/annurev-physiol-020518-114546","article-title":"Central mechanisms for thermoregulation","volume":"81","author":"Morrison","year":"2019","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0230","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/jcbfm.2012.157","article-title":"Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia","volume":"33","author":"Muzzi","year":"2013","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0235","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1007\/s00421-025-05796-0","article-title":"Influence of local temperature on motor unit behavior during rapid contractions in humans","volume":"125","author":"Ota","year":"2025","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0240","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1042\/BJ20091515","article-title":"AR-c155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10","volume":"425","author":"Ovens","year":"2010","journal-title":"Biochem. J"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0245","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/eurheartj\/ehx720","volume":"39","author":"Parati","year":"2018","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0250","unstructured":"Paxinos G, Watson C, eds (2007) The rat brain in stereotaxic coordinates, sixth edition. San Diego: Elsevier Academic Press."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0255","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jnr.20307","article-title":"Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain","volume":"79","author":"Pellerin","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0260","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-444-63912-7.00001-1","article-title":"The thermoregulation system and how it works","volume":"156","author":"Romanovsky","year":"2018","journal-title":"Handb. Clin. Neurol."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.08.030_b0265","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1152\/japplphysiol.01173.2001","article-title":"Selected contribution: ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality","volume":"92","author":"Romanovsky","year":"2002","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0270","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1126\/science.3131879","article-title":"Expression of c-fos protein in brain: metabolic mapping at the cellular level","volume":"240","author":"Sagar","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0275","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1159\/000489058","article-title":"Metabolic plasticity enables circadian adaptation to acute hypoxia in zebrafish cells","volume":"46","author":"Sandbichler","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0280","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1515\/cclm-2016-0438","article-title":"Lactic acidosis: an update","volume":"55","author":"Seheult","year":"2017","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0285","doi-asserted-by":"crossref","first-page":"4168","DOI":"10.1523\/JNEUROSCI.5036-14.2015","article-title":"Channel-mediated lactate release by k\u207a-stimulated astrocytes","volume":"35","author":"Sotelo-Hitschfeld","year":"2015","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0290","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1146\/annurev.physiol.64.081501.155856","article-title":"Hypoxia-induced anapyrexia: implications and putative mediators","volume":"64","author":"Steiner","year":"2002","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0295","doi-asserted-by":"crossref","first-page":"R1412","DOI":"10.1152\/ajpregu.00328.2002","article-title":"A neurochemical mechanism for hypoxia-induced anapyrexia","volume":"283","author":"Steiner","year":"2002","journal-title":"Am. J. Physiol. Regulatory, Integrative and Comparative Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0300","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.cell.2011.02.018","article-title":"Astrocyte-neuron lactate transport is required for long-term memory formation","volume":"144","author":"Suzuki","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0305","article-title":"Corticospinal and spinal excitability during peripheral or central cooling in humans","volume":"112","author":"Talebian","year":"2023","journal-title":"J. Therm. Biol"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00584743","article-title":"Effects of air constituents on thermosensitivities of preoptic neurons: hypoxia versus hypercapnia","volume":"409","author":"Tamaki","year":"1987","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0315","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.cell.2016.08.028","article-title":"Warm-sensitive neurons that control body temperature","volume":"167","author":"Tan","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0320","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1038\/ncomms4284","article-title":"Lactate-mediated glia-neuronal signalling in the mammalian brain","volume":"5","author":"Tang","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0325","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.243194","article-title":"Different patterns of chronic hypoxia lead to hierarchical adaptive mechanisms in goldfish metabolism","volume":"225","author":"Thoral","year":"2022","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0335","first-page":"351","article-title":"Acute hypoxia blunts cold sensitivity through the inhibition of the lateral parabrachial nucleus in rats","volume":"75","author":"Wang","year":"2023","journal-title":"Sheng Li Xue Bao"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0330","article-title":"Intermittent hypoxia preconditioning can attenuate acute hypoxic injury after a sustained normobaric hypoxic exposure: a randomized clinical trial","volume":"30","author":"Wang","year":"2024","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0340","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev.ph.53.030191.000443","article-title":"Interactions between hypoxia and hypothermia","volume":"53","author":"Wood","year":"1991","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0345","first-page":"1249","article-title":"Oxygen as a modulator of body temperature","volume":"28","author":"Wood","year":"1995","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0350","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1440-1681.1998.tb02196.x","article-title":"Effect of gender on thermoregulation and survival of hypoxic rats","volume":"25","author":"Wood","year":"1998","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0355","doi-asserted-by":"crossref","first-page":"13398","DOI":"10.3390\/ijms241713398","article-title":"Lactate metabolism, signaling, and function in brain development, synaptic plasticity, angiogenesis, and neurodegenerative diseases","volume":"24","author":"Wu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0360","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3390\/brainsci14040327","article-title":"Hippocampal lactate-infusion enhances spatial memory correlated with monocarboxylate transporter 2 and lactylation","volume":"14","author":"Wu","year":"2024","journal-title":"Brain Sci."},{"key":"10.1016\/j.neuroscience.2026.08.030_b0365","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2019.108563","article-title":"Expression of lactate dehydrogenase is induced during hypoxia via HIF-1 in the mud crab scylla paramamosain","volume":"225","author":"Xie","year":"2019","journal-title":"Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0370","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.neuroscience.2023.11.012","article-title":"Cerebral lactate participates in hypoxia-induced anapyrexia through its receptor g protein-coupled receptor 81","volume":"536","author":"Yang","year":"2024","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0375","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1073\/pnas.1616255114","article-title":"A hypothalamic circuit that controls body temperature","volume":"114","author":"Zhao","year":"2017","journal-title":"PNAS"},{"key":"10.1016\/j.neuroscience.2026.08.030_b0380","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1080\/17461391.2015.1111938","article-title":"Central dopaminergic neurotransmission plays an important role in thermoregulation and performance during endurance exercise","volume":"16","author":"Zheng","year":"2016","journal-title":"Eur. J. Sport Sci."}],"container-title":["Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452226005737?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306452226005737?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:20:09Z","timestamp":1790770809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306452226005737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":76,"alternative-id":["S0306452226005737"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroscience.2026.08.030","relation":{},"ISSN":["0306-4522"],"issn-type":[{"value":"0306-4522","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxic preconditioning alleviates hypoxia-induced anapyrexia by attenuating cerebral lactate elevation","name":"articletitle","label":"Article Title"},{"value":"Neuroscience","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroscience.2026.08.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of International Brain Research Organization (IBRO).","name":"copyright","label":"Copyright"}]}}