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Physiol."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0355","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.pain.2009.10.006","article-title":"Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human","volume":"148","author":"Obreja","year":"2010","journal-title":"Pain"},{"issue":"9","key":"10.1016\/j.neuroscience.2026.09.006_b0360","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/nn896","article-title":"Unmyelinated tactile afferents signal touch and project to insular cortex","volume":"5","author":"Olausson","year":"2002","journal-title":"Nat. Neurosci."},{"issue":"2","key":"10.1016\/j.neuroscience.2026.09.006_b0365","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.neubiorev.2008.09.011","article-title":"The neurophysiology of unmyelinated tactile afferents","volume":"34","author":"Olausson","year":"2010","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0370","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/wdev.229","article-title":"The specification and wiring of mammalian cutaneous low-threshold mechanoreceptors","volume":"5","author":"Olson","year":"2016","journal-title":"WIREs Dev. Biol."},{"key":"10.1016\/j.neuroscience.2026.09.006_b0375","doi-asserted-by":"crossref","unstructured":"Orlin, D.J., Munoz, A., Berryman, S., Semidey, D., Murthy, S.E., 2025. Targeting Tmem63b and Piezo2 in C-fiber low threshold mechanoreceptor: limitation of Vglut3-IRES-Cre. bioRxiv. 10.1101\/2025.07.26.666969.","DOI":"10.1016\/j.bpj.2025.10.043"},{"issue":"18","key":"10.1016\/j.neuroscience.2026.09.006_b0380","doi-asserted-by":"crossref","first-page":"7227","DOI":"10.1523\/JNEUROSCI.23-18-07227.2003","article-title":"KCNQ\/M currents in sensory neurons: significance for pain therapy","volume":"23","author":"Passmore","year":"2003","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0385","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1113\/jphysiol.1968.sp008576","article-title":"Myelinated afferent fibres innervating the primate skin and their response to noxious stimuli","volume":"197","author":"Perl","year":"1968","journal-title":"J. Physiol."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0390","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0306-4522(97)00629-5","article-title":"Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves","volume":"85","author":"Perry","year":"1998","journal-title":"Neuroscience"},{"issue":"26","key":"10.1016\/j.neuroscience.2026.09.006_b0395","doi-asserted-by":"crossref","first-page":"9382","DOI":"10.1073\/pnas.0501549102","article-title":"Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior","volume":"102","author":"Priest","year":"2005","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.09.006_b0400","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.cell.2024.02.006","article-title":"A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes","volume":"187","author":"Qi","year":"2024","journal-title":"Cell"},{"issue":"7529","key":"10.1016\/j.neuroscience.2026.09.006_b0405","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nature13980","article-title":"Piezo2 is the major transducer of mechanical forces for touch sensation in mice","volume":"516","author":"Ranade","year":"2014","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.neuroscience.2026.09.006_b0410","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1152\/jn.2001.86.2.629","article-title":"Contribution of Nav1.8 sodium channels to action potential electrogenesis in DRG neurons","volume":"86","author":"Renganathan","year":"2001","journal-title":"J. Neurophysiol."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0415","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/cne.900960303","article-title":"The cytoarchitectonic organization of the spinal cord in the cat","volume":"96","author":"Rexed","year":"1952","journal-title":"J Comp Neurol"},{"issue":"4","key":"10.1016\/j.neuroscience.2026.09.006_b0420","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/cne.902810402","article-title":"Morphological characterization of substance P-like immunoreactive glomeruli in the superficial dorsal horn of the rat spinal cord and trigeminal subnucleus caudalis: a quantitative study","volume":"281","author":"Ribeiro-da-Silva","year":"1989","journal-title":"J Comp Neurol"},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0425","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.2006.121483","article-title":"Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons","volume":"579","author":"Rush","year":"2007","journal-title":"J. Physiol."},{"key":"10.1016\/j.neuroscience.2026.09.006_b0430","series-title":"Sensory neurons: diversity, development, and plasticity","author":"Scott","year":"1992"},{"issue":"7273","key":"10.1016\/j.neuroscience.2026.09.006_b0435","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nature08505","article-title":"Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors","volume":"462","author":"Seal","year":"2009","journal-title":"Nature"},{"issue":"Pt 3) (Pt 3","key":"10.1016\/j.neuroscience.2026.09.006_b0440","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/j.1469-7793.1999.799ab.x","article-title":"Activity-dependent slowing of conduction differentiates functional subtypes of C fibres innervating human skin","volume":"515","author":"Serra","year":"1999","journal-title":"J. Physiol."},{"issue":"7790","key":"10.1016\/j.neuroscience.2026.09.006_b0445","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1038\/s41586-019-1900-1","article-title":"The emergence of transcriptional identity in somatosensory neurons","volume":"577","author":"Sharma","year":"2020","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0450","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1152\/jn.1985.54.3.491","article-title":"Sensory receptors with unmyelinated (C) fibers innervating the skin of the rabbit's ear","volume":"54","author":"Shea","year":"1985","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.neuroscience.2026.09.006_b0455","series-title":"The integrative action of the nervous system [doi:10.1037\/13798-000]","author":"Sherrington","year":"1906"},{"issue":"10","key":"10.1016\/j.neuroscience.2026.09.006_b0460","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/j.pain.2012.04.022","article-title":"Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system","volume":"153","author":"Shields","year":"2012","journal-title":"Pain"},{"issue":"6","key":"10.1016\/j.neuroscience.2026.09.006_b0465","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S0092-8674(03)00158-2","article-title":"ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures","volume":"112","author":"Story","year":"2003","journal-title":"Cell"},{"issue":"4774","key":"10.1016\/j.neuroscience.2026.09.006_b0470","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1126\/science.3764416","article-title":"Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin","volume":"234","author":"Sugiura","year":"1986","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.neuroscience.2026.09.006_b0475","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1152\/jn.1968.31.2.301","article-title":"The sense of flutter-vibration: comparison of the human capacity with response patterns of mechanoreceptive afferents from the monkey hand","volume":"31","author":"Talbot","year":"1968","journal-title":"J. Neurophysiol."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0480","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3109\/08990229409051392","article-title":"Modality-dependent modulation of conduction by impulse activity in functionally characterized single cutaneous afferents in the rat","volume":"11","author":"Thalhammer","year":"1994","journal-title":"Somatosens. Mot. Res."},{"issue":"12","key":"10.1016\/j.neuroscience.2026.09.006_b0485","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nrn2947","article-title":"Neuronal circuitry for pain processing in the dorsal horn","volume":"11","author":"Todd","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0490","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/j.1748-1716.1974.tb05755.x","article-title":"Afferent G units responding to mechanical, thermal and chemical stimuli in human non-glabrous skin","volume":"92","author":"Torebj\u00f6rk","year":"1974","journal-title":"Acta Physiol. Scand."},{"issue":"6","key":"10.1016\/j.neuroscience.2026.09.006_b0495","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1523\/JNEUROSCI.4584-05.2006","article-title":"Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord","volume":"26","author":"Torsney","year":"2006","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0500","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1152\/jn.1988.59.1.41","article-title":"The spinal projection of individual identified A-delta- and C-fibers","volume":"59","author":"Traub","year":"1988","journal-title":"J. Neurophysiol."},{"issue":"2\u20133","key":"10.1016\/j.neuroscience.2026.09.006_b0505","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0304-3959(98)00184-5","article-title":"The cortical representation of pain","volume":"79","author":"Treede","year":"1999","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0510","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.tins.2013.12.002","article-title":"Opening paths to novel analgesics: the role of potassium channels in chronic pain","volume":"37","author":"Tsantoulas","year":"2014","journal-title":"Trends Neurosci."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0515","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/nn.3881","article-title":"Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing","volume":"18","author":"Usoskin","year":"2015","journal-title":"Nat. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.neuroscience.2026.09.006_b0520","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0006-8993(93)90968-S","article-title":"A system of unmyelinated afferents for innocuous mechanoreception in the human skin","volume":"628","author":"Vallbo","year":"1993","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.neuroscience.2026.09.006_b0525","first-page":"392","article-title":"Impulses recorded with micro-electrodes in human muscle nerves during stimulation of mechanoreceptors and voluntary contractions","volume":"23","author":"Vallbo","year":"1967","journal-title":"Electroencephalogr. Clin. 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J. Neurosci."},{"issue":"3","key":"10.1016\/j.neuroscience.2026.09.006_b0545","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0306-4522(90)90024-X","article-title":"Electrophysiological properties of subpopulations of rat dorsal root ganglion neurons in vitro","volume":"36","author":"Waddell","year":"1990","journal-title":"Neuroscience"},{"key":"10.1016\/j.neuroscience.2026.09.006_b0550","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.cobeha.2021.10.010","article-title":"Slow touch in non-human species: translational research into the C-tactile (CT) afferent system","volume":"43","author":"Watkins","year":"2022","journal-title":"Curr. Opin. Behav. Sci."},{"issue":"1","key":"10.1016\/j.neuroscience.2026.09.006_b0555","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1152\/jn.00587.2020","article-title":"Evidence for sparse C-tactile afferent innervation of glabrous human hand skin","volume":"125","author":"Watkins","year":"2021","journal-title":"J. Neurophysiol."},{"issue":"4","key":"10.1016\/j.neuroscience.2026.09.006_b0560","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1152\/jn.00939.2016","article-title":"Optimal delineation of single C-tactile and C-nociceptive afferents in humans by latency slowing","volume":"117","author":"Watkins","year":"2017","journal-title":"J. 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