{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:03:01Z","timestamp":1793041381592,"version":"4.5.0"},"reference-count":249,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011906","name":"Joe Niekro Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011906","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100023887","name":"Texas A&M University Health Science Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100023887","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["1R01NS117606"],"award-info":[{"award-number":["1R01NS117606"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["1R61NS119640"],"award-info":[{"award-number":["1R61NS119640"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS131469"],"award-info":[{"award-number":["R01NS131469"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K23NS121628"],"award-info":[{"award-number":["K23NS121628"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1916894"],"award-info":[{"award-number":["1916894"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1R01AG073659"],"award-info":[{"award-number":["1R01AG073659"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["neurotherapeuticsjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotherapeutics"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.neurot.2024.e00515","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T07:34:24Z","timestamp":1735025664000},"page":"e00515","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside"],"prefix":"10.1016","volume":"22","author":[{"given":"Sidra","family":"Tabassum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Hun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bosco Seong Kyu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron M.","family":"Gusdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimahn A.","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefang S.","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.mcna.2019.11.001","article-title":"Traumatic brain injury: an overview of epidemiology, pathophysiology, and medical management","volume":"104","author":"Capizzi","year":"2020","journal-title":"Med Clin North Am"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib2","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S1474-4422(22)00309-X","article-title":"Traumatic brain injury: progress and challenges in prevention, clinical care, and research","volume":"21","author":"Maas","year":"2022","journal-title":"Lancet Neurol"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2023-075049","article-title":"Global, regional and national burden of traumatic brain injury and spinal cord injury, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"13","author":"Guan","year":"2023","journal-title":"BMJ Open"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib4","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.pmr.2016.12.001","article-title":"Pathophysiology of traumatic brain injury","volume":"28","author":"Dixon","year":"2017","journal-title":"Phys Med Rehabil Clin N Am"},{"key":"10.1016\/j.neurot.2024.e00515_bib5","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1136\/bmj.p1130","article-title":"Head injury: assessment and early management-summary of updated NICE guidance","volume":"381","author":"Rajesh","year":"2023","journal-title":"BMJ"},{"issue":"12","key":"10.1016\/j.neurot.2024.e00515_bib6","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S1474-4422(11)70243-5","article-title":"Spreading depolarisations and outcome after traumatic brain injury: a prospective observational study","volume":"10","author":"Hartings","year":"2011","journal-title":"Lancet Neurol"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib7","first-page":"1185","article-title":"Effect of the modified Glasgow Coma Scale score criteria for mild traumatic brain injury on mortality prediction: comparing classic and modified Glasgow Coma Scale score model scores of 13","volume":"71","author":"Mena","year":"2011","journal-title":"J\u00a0Trauma"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib8","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/S0003-9993(03)00287-9","article-title":"Outcome 3 to 5 years after moderate to severe traumatic brain injury","volume":"84","author":"Dikmen","year":"2003","journal-title":"Arch Phys Med Rehabil"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib9","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/fcp.12767","article-title":"Oxidative stress and mitochondrial dysfunction following traumatic brain injury: from mechanistic view to targeted therapeutic opportunities","volume":"36","author":"Hakiminia","year":"2022","journal-title":"Fundam Clin Pharmacol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/bja\/aem131","article-title":"Pathophysiology of traumatic brain injury","volume":"99","author":"Werner","year":"2007","journal-title":"Br J Anaesth"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib11","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s00424-007-0296-1","article-title":"Mitochondria and Ca(2+) signaling: old guests, new functions","volume":"455","author":"Graier","year":"2007","journal-title":"Pfl\u00fcgers Archiv"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib12","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1515\/revneuro-2019-0086","article-title":"Brain energetics, mitochondria, and traumatic brain injury","volume":"31","author":"Benaroya","year":"2020","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.neurot.2024.e00515_bib13","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8416763","article-title":"Oxidative stress: harms and benefits for human health","volume":"2017","author":"Pizzino","year":"2017","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1089\/neu.2000.17.53","article-title":"Characterization of plasma magnesium concentration and oxidative stress following graded traumatic brain injury in humans","volume":"17","author":"Cernak","year":"2000","journal-title":"J\u00a0Neurotrauma"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib15","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0090-3019(96)00461-2","article-title":"Oxidative stress following traumatic brain injury in rats","volume":"47","author":"Awasthi","year":"1997","journal-title":"Surg Neurol"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib16","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1046\/j.1471-4159.2000.0752178.x","article-title":"Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates","volume":"75","author":"Tyurin","year":"2000","journal-title":"J\u00a0Neurochem"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib17","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.mad.2010.03.009","article-title":"Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: susceptibility of skeletal muscles to oxidative injury","volume":"131","author":"Szczesny","year":"2010","journal-title":"Mech Ageing Dev"},{"issue":"Suppl 2","key":"10.1016\/j.neurot.2024.e00515_bib18","first-page":"S425","article-title":"Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury","volume":"9","author":"Hall","year":"1992","journal-title":"J\u00a0Neurotrauma"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib19","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1089\/089771501317095250","article-title":"Monitoring of reactive oxygen species production after traumatic brain injury in rats with microdialysis and the 4-hydroxybenzoic acid trapping method","volume":"18","author":"Marklund","year":"2001","journal-title":"J\u00a0Neurotrauma"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib20","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib21","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1227\/01.NEU.0000156715.04900.E6","article-title":"Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats","volume":"56","author":"Tavazzi","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neurot.2024.e00515_bib22","article-title":"Rhein and rhubarb similarly protect the blood-brain barrier after experimental traumatic brain injury via gp91(phox) subunit of NADPH oxidase\/ROS\/ERK\/MMP-9 signaling pathway","volume":"6","author":"Wang","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.freeradbiomed.2014.08.025","article-title":"A\u00a0time course of NADPH-oxidase up-regulation and endothelial nitric oxide synthase activation in the hippocampus following neurotrauma","volume":"77","author":"Ansari","year":"2014","journal-title":"Free Radic Biol Med"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib24","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.neurobiolaging.2012.11.013","article-title":"Traumatic brain injury in aged animals increases lesion size and chronically alters microglial\/macrophage classical and alternative activation states","volume":"34","author":"Kumar","year":"2013","journal-title":"Neurobiol Aging"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib25","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1089\/ars.2009.2578","article-title":"NOX enzymes in the central nervous system: from signaling to disease","volume":"11","author":"Sorce","year":"2009","journal-title":"Antioxidants Redox Signal"},{"key":"10.1016\/j.neurot.2024.e00515_bib26","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.redox.2018.03.005","article-title":"NADPH oxidases in traumatic brain injury - promising therapeutic targets?","volume":"16","author":"Ma","year":"2018","journal-title":"Redox Biol"},{"key":"10.1016\/j.neurot.2024.e00515_bib27","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/1742-2094-10-155","article-title":"Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury","volume":"10","author":"Cooney","year":"2013","journal-title":"J\u00a0Neuroinflammation"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib28","article-title":"Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neurot.2024.e00515_bib29","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.freeradbiomed.2017.09.017","article-title":"Regulatory role of NADPH oxidase 2 in the polarization dynamics and neurotoxicity of microglia\/macrophages after traumatic brain injury","volume":"113","author":"Wang","year":"2017","journal-title":"Free Radic Biol Med"},{"issue":"46","key":"10.1016\/j.neurot.2024.e00515_bib30","doi-asserted-by":"crossref","first-page":"12315","DOI":"10.1073\/pnas.1705034114","article-title":"NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage","volume":"114","author":"Casas","year":"2017","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib31","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12974-019-1478-4","article-title":"Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage","volume":"16","author":"Hernandez-Espinosa","year":"2019","journal-title":"J\u00a0Neuroinflammation"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12781","article-title":"The role of astrocytes in oxidative stress of central nervous system: a mixed blessing","volume":"53","author":"Chen","year":"2020","journal-title":"Cell Prolif"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib33","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.4103\/1673-5374.390973","article-title":"NADPH oxidase 4 (NOX4) as a biomarker and therapeutic target in neurodegenerative diseases","volume":"19","author":"Boonpraman","year":"2024","journal-title":"Neural Regen Res"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib34","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1186\/s12974-016-0769-2","article-title":"Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury","volume":"13","author":"Skovira","year":"2016","journal-title":"J\u00a0Neuroinflammation"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib35","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/NEN.0000000000000021","article-title":"Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation","volume":"73","author":"Loane","year":"2014","journal-title":"J\u00a0Neuropathol Exp Neurol"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines8100389","article-title":"Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions","volume":"8","author":"Jarrahi","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.neurot.2024.e00515_bib37","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3389\/fnins.2015.00112","article-title":"Glycolysis and the significance of lactate in traumatic brain injury","volume":"9","author":"Carpenter","year":"2015","journal-title":"Front Neurosci"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib38","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1007\/s00213-020-05482-3","article-title":"Chrysin attenuates traumatic brain injury-induced recognition memory decline, and anxiety\/depression-like behaviors in rats: insights into underlying mechanisms","volume":"237","author":"Rashno","year":"2020","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.neurot.2024.e00515_bib39","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.expneurol.2012.09.019","article-title":"Neuroprotective effect of Pycnogenol(R) following traumatic brain injury","volume":"239","author":"Scheff","year":"2013","journal-title":"Exp Neurol"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib40","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s10571-014-0070-9","article-title":"Anti-apoptotic and anti-oxidative roles of quercetin after traumatic brain injury","volume":"34","author":"Yang","year":"2014","journal-title":"Cell Mol Neurobiol"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib41","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/jcmm.13313","article-title":"Neuroprotection by quercetin via mitochondrial function adaptation in traumatic brain injury: PGC-1alpha pathway as a potential mechanism","volume":"22","author":"Li","year":"2018","journal-title":"J\u00a0Cell Mol Med"},{"issue":"1-2","key":"10.1016\/j.neurot.2024.e00515_bib42","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s11010-006-9253-0","article-title":"Neuroprotection by resveratrol against traumatic brain injury in rats","volume":"294","author":"Ates","year":"2007","journal-title":"Mol Cell Biochem"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib43","first-page":"924","article-title":"Resveratrol treatment prevents hippocampal neurodegeneration in a rodent model of traumatic brain injury","volume":"27","author":"Atalay","year":"2017","journal-title":"Turk Neurosurg"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib44","first-page":"3212","article-title":"Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1","volume":"17","author":"Zou","year":"2018","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib45","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.12659\/MSM.909042","article-title":"Resveratrol attenuates cognitive deficits of traumatic brain injury by activating p38 signaling in the brain","volume":"24","author":"Shi","year":"2018","journal-title":"Med Sci Monit"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib46","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1097\/TA.0b013e31827e1f51","article-title":"Resveratrol decreases inflammation in the brain of mice with mild traumatic brain injury","volume":"74","author":"Gatson","year":"2013","journal-title":"J\u00a0Trauma Acute Care Surg"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib47","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.123","article-title":"Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death","volume":"5","author":"Lin","year":"2014","journal-title":"Cell Death Dis"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib48","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1016\/j.injury.2021.08.019","article-title":"Resveratrol ameliorates thoracic blast exposure-induced inflammation, endoplasmic reticulum stress and apoptosis in the brain through the Nrf2\/Keap1 and NF-kappaB signaling pathway","volume":"52","author":"Cong","year":"2021","journal-title":"Injury"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib49","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1089\/neu.2005.22.1112","article-title":"Administration of riboflavin improves behavioral outcome and reduces edema formation and glial fibrillary acidic protein expression after traumatic brain injury","volume":"22","author":"Hoane","year":"2005","journal-title":"J\u00a0Neurotrauma"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib50","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1089\/089771503770802871","article-title":"Treatment with vitamin B3 improves functional recovery and reduces GFAP expression following traumatic brain injury in rats","volume":"20","author":"Hoane","year":"2003","journal-title":"J\u00a0Neurotrauma"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib51","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.neuroscience.2008.04.044","article-title":"Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat","volume":"154","author":"Hoane","year":"2008","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib52","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4161\/oxim.3.2.11315","article-title":"Sustained delivery of nicotinamide limits cortical injury and improves functional recovery following traumatic brain injury","volume":"3","author":"Goffus","year":"2010","journal-title":"Oxid Med Cell Longev"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib53","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.bbr.2011.06.009","article-title":"Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury","volume":"224","author":"Vonder","year":"2011","journal-title":"Behav Brain Res"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib54","article-title":"Nicotinamide improves functional recovery via regulation of the RAGE\/JNK\/NF-kappaB signaling pathway after brain injury","volume":"8","author":"Alam","year":"2019","journal-title":"J\u00a0Clin Med"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib55","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1089\/neu.1991.8.281","article-title":"Intracerebral administration of alpha-tocopherol-containing liposomes facilitates behavioral recovery in rats with bilateral lesions of the frontal cortex","volume":"8","author":"Stein","year":"1991","journal-title":"J\u00a0Neurotrauma"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib56","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1177\/1545968309348318","article-title":"Vitamin E protects against oxidative damage and learning disability after mild traumatic brain injury in rats","volume":"24","author":"Aiguo","year":"2010","journal-title":"Neurorehabilitation Neural Repair"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib57","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/j.1471-4159.2004.02560.x","article-title":"Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury","volume":"90","author":"Conte","year":"2004","journal-title":"J\u00a0Neurochem"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib58","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1097\/00006123-199808000-00095","article-title":"Time-level relationship for lipid peroxidation and the protective effect of alpha-tocopherol in experimental mild and severe brain injury","volume":"43","author":"Inci","year":"1998","journal-title":"Neurosurgery"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090617","article-title":"Efficacy of N-acetyl cysteine in traumatic brain injury","volume":"9","author":"Eakin","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib60","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s11064-006-9040-z","article-title":"Neuroprotective effects of N-acetylcysteine on experimental closed head trauma in rats","volume":"31","author":"Hicdonmez","year":"2006","journal-title":"Neurochem Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib61","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/716458","article-title":"Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine","volume":"2008","author":"Chen","year":"2008","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.neurot.2024.e00515_bib62","doi-asserted-by":"crossref","first-page":"650","DOI":"10.3389\/fneur.2019.00650","article-title":"N-Acetylcysteine amide ameliorates blast-induced changes in blood-brain barrier integrity in rats","volume":"10","author":"Kawoos","year":"2019","journal-title":"Front Neurol"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib63","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1177\/0271678X17718106","article-title":"Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes and modifies neuroinflammation in a rat model of mild traumatic brain injury","volume":"38","author":"Haber","year":"2018","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib64","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1600-079X.1998.tb00384.x","article-title":"Protective effect of melatonin in a model of traumatic brain injury in mice","volume":"25","author":"Mesenge","year":"1998","journal-title":"J\u00a0Pineal Res"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib65","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neulet.2005.05.055","article-title":"Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats","volume":"385","author":"Ozdemir","year":"2005","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib66","doi-asserted-by":"crossref","first-page":"631","DOI":"10.33549\/physiolres.930709","article-title":"Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats","volume":"54","author":"Ozdemir","year":"2005","journal-title":"Physiol Res"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib67","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1600-0404.2005.00463.x","article-title":"The effects of environmental light--dark changes on experimental mild traumatic brain injury","volume":"112","author":"Ucar","year":"2005","journal-title":"Acta Neurol Scand"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib68","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ijdevneu.2006.08.003","article-title":"Effect of pinealectomy and melatonin replacement on morphological and biochemical recovery after traumatic brain injury","volume":"24","author":"Ates","year":"2006","journal-title":"Int J Dev Neurosci"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib69","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.arcmed.2013.04.002","article-title":"Effect of melatonin on intracranial pressure and brain edema following traumatic brain injury: role of oxidative stresses","volume":"44","author":"Dehghan","year":"2013","journal-title":"Arch Med Res"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib70","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1096\/fj.03-0323fje","article-title":"Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1","volume":"18","author":"Beni","year":"2004","journal-title":"Faseb J"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib71","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.4103\/1673-5374.135312","article-title":"Melatonin reduces traumatic brain injury-induced oxidative stress in the cerebral cortex and blood of rats","volume":"9","author":"Senol","year":"2014","journal-title":"Neural Regen Res"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib72","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s11011-014-9623-3","article-title":"Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: possible involvement of TRPM2 channels","volume":"30","author":"Yuruker","year":"2015","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.neurot.2024.e00515_bib73","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.neuint.2015.10.008","article-title":"Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice","volume":"91","author":"Ding","year":"2015","journal-title":"Neurochem Int"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib74","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/jpi.12337","article-title":"Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy","volume":"61","author":"Lin","year":"2016","journal-title":"J\u00a0Pineal Res"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib75","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/jpi.12344","article-title":"Melatonin attenuates neuronal apoptosis through up-regulation of K(+) -Cl(-) cotransporter KCC2 expression following traumatic brain injury in rats","volume":"61","author":"Wu","year":"2016","journal-title":"J\u00a0Pineal Res"},{"issue":"7","key":"10.1016\/j.neurot.2024.e00515_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/cells8070760","article-title":"Neurological enhancement effects of melatonin against brain injury-induced oxidative stress, neuroinflammation, and neurodegeneration via AMPK\/CREB signaling","volume":"8","author":"Rehman","year":"2019","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib77","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0006-8993(93)90778-L","article-title":"Estrogen improves biochemical and neurologic outcome following traumatic brain injury in male rats, but not in females","volume":"608","author":"Emerson","year":"1993","journal-title":"Brain Res"},{"issue":"17","key":"10.1016\/j.neurot.2024.e00515_bib78","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1089\/neu.2013.2854","article-title":"17beta-estradiol confers protection after traumatic brain injury in the rat and involves activation of G protein-coupled estrogen receptor 1","volume":"30","author":"Day","year":"2013","journal-title":"J\u00a0Neurotrauma"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib79","first-page":"138","article-title":"Estrogen provides neuroprotection against brain edema and blood brain barrier disruption through both estrogen receptors alpha and beta following traumatic brain injury","volume":"18","author":"Naderi","year":"2015","journal-title":"Iran J Basic Med Sci"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib80","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1186\/s13054-021-03844-7","article-title":"17alpha-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a randomized control trial","volume":"25","author":"Mayer","year":"2021","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib81","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1002\/jcp.26083","article-title":"17beta-estradiol rescues damages following traumatic brain injury from molecule to behavior in mice","volume":"233","author":"Lu","year":"2018","journal-title":"J\u00a0Cell Physiol"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib82","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1139\/Y09-126","article-title":"Effect of sex steroid hormones on brain edema, intracranial pressure, and neurologic outcomes after traumatic brain injury","volume":"88","author":"Shahrokhi","year":"2010","journal-title":"Can J Physiol Pharmacol"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib83","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1006\/exnr.1996.0063","article-title":"Progesterone rapidly decreases brain edema: treatment delayed up to 24 hours is still effective","volume":"138","author":"Roof","year":"1996","journal-title":"Exp Neurol"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib84","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1089\/089771501750451820","article-title":"Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats","volume":"18","author":"Wright","year":"2001","journal-title":"J\u00a0Neurotrauma"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib85","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1006\/exnr.1994.1147","article-title":"Progesterone facilitates cognitive recovery and reduces secondary neuronal loss caused by cortical contusion injury in male rats","volume":"129","author":"Roof","year":"1994","journal-title":"Exp Neurol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib86","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0087252","article-title":"Progesterone treatment shows benefit in a pediatric model of moderate to severe bilateral brain injury","volume":"9","author":"Geddes","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib87","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.3892\/etm.2014.1840","article-title":"Progesterone protects blood-brain barrier function and improves neurological outcome following traumatic brain injury in rats","volume":"8","author":"Si","year":"2014","journal-title":"Exp Ther Med"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib88","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/jnc.14220","article-title":"Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection","volume":"143","author":"Kramer","year":"2017","journal-title":"J\u00a0Neurochem"},{"key":"10.1016\/j.neurot.2024.e00515_bib89","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.nbd.2015.07.001","article-title":"Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage","volume":"82","author":"Iniaghe","year":"2015","journal-title":"Neurobiol Dis"},{"issue":"13","key":"10.1016\/j.neurot.2024.e00515_bib90","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1089\/neu.2017.5260","article-title":"Dimethyl fumarate attenuates neuroinflammation and neurobehavioral deficits induced by experimental traumatic brain injury","volume":"35","author":"Casili","year":"2018","journal-title":"J\u00a0Neurotrauma"},{"key":"10.1016\/j.neurot.2024.e00515_bib91","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.neuint.2018.05.011","article-title":"Fisetin alleviates oxidative stress after traumatic brain injury via the Nrf2-ARE pathway","volume":"118","author":"Zhang","year":"2018","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neurot.2024.e00515_bib92","article-title":"Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways","volume":"7","author":"Zhang","year":"2017","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib93","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.neulet.2009.04.028","article-title":"Sulforaphane improves cognitive function administered following traumatic brain injury","volume":"460","author":"Dash","year":"2009","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neurot.2024.e00515_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.146818","article-title":"TBHQ improved neurological recovery after traumatic brain injury by inhibiting the overactivation of astrocytes","volume":"1739","author":"Zhang","year":"2020","journal-title":"Brain Res"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib95","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1007\/s11064-017-2372-z","article-title":"Protective role of apocynin via suppression of neuronal autophagy and TLR4\/NF-kappaB signaling pathway in a rat model of traumatic brain injury","volume":"42","author":"Feng","year":"2017","journal-title":"Neurochem Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib96","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.brainres.2012.08.032","article-title":"Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation","volume":"1481","author":"Choi","year":"2012","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib97","doi-asserted-by":"crossref","first-page":"7717","DOI":"10.1038\/s41598-019-44147-w","article-title":"Synergistic role of oxidative stress and blood-brain barrier permeability as injury mechanisms in the acute pathophysiology of blast-induced neurotrauma","volume":"9","author":"Kuriakose","year":"2019","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib98","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.neuint.2013.09.012","article-title":"The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: role of inflammatory and oxidative brain damage","volume":"63","author":"Ferreira","year":"2013","journal-title":"Neurochem Int"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib99","doi-asserted-by":"crossref","first-page":"4088","DOI":"10.1111\/jcmm.14296","article-title":"Alpha lipoic acid inhibits oxidative stress-induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury","volume":"23","author":"Xia","year":"2019","journal-title":"J\u00a0Cell Mol Med"},{"key":"10.1016\/j.neurot.2024.e00515_bib100","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3389\/fnins.2019.00026","article-title":"Carnosic acid mitigates early brain injury after subarachnoid hemorrhage: possible involvement of the SIRT1\/p66shc signaling pathway","volume":"13","author":"Teng","year":"2019","journal-title":"Front Neurosci"},{"issue":"13","key":"10.1016\/j.neurot.2024.e00515_bib101","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1089\/neu.2018.6155","article-title":"Carnosic acid improves outcome after repetitive mild traumatic brain injury","volume":"36","author":"Maynard","year":"2019","journal-title":"J\u00a0Neurotrauma"},{"key":"10.1016\/j.neurot.2024.e00515_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2021.105255","article-title":"Antioxidant therapies in traumatic brain injury","volume":"152","author":"Davis","year":"2022","journal-title":"Neurochem Int"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib103","doi-asserted-by":"crossref","DOI":"10.3390\/antiox9030260","article-title":"Antioxidant therapies in traumatic brain injury","volume":"9","author":"Di Pietro","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.neurot.2024.e00515_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2022.113987","article-title":"Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point","volume":"351","author":"Tabet","year":"2022","journal-title":"Exp Neurol"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib105","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10020250","article-title":"Mitoquinone helps combat the neurological, cognitive, and molecular consequences of open head traumatic brain injury at chronic time point","volume":"10","author":"Haidar","year":"2022","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib106","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054163","article-title":"Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study","volume":"8","author":"Hoffer","year":"2013","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.neurot.2024.e00515_bib107","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0180280","article-title":"Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children","volume":"12","author":"Clark","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib108","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s13063-019-4008-x","article-title":"Evaluation of the effects of pycnogenol (French maritime pine bark extract) supplementation on inflammatory biomarkers and nutritional and clinical status in traumatic brain injury patients in an intensive care unit: a randomized clinical trial protocol","volume":"21","author":"Malekahmadi","year":"2020","journal-title":"Trials"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib109","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1080\/02699052.2019.1566968","article-title":"Safety and feasibility of minocycline in treatment of acute traumatic brain injury","volume":"33","author":"Meythaler","year":"2019","journal-title":"Brain Inj"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib110","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00414-006-0126-6","article-title":"Neuronal and glial apoptosis in human traumatic brain injury","volume":"121","author":"Dressler","year":"2007","journal-title":"Int J Leg Med"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib111","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s10735-024-10192-7","article-title":"Human neural stem cell secretome relieves endoplasmic reticulum stress-induced apoptosis and improves neuronal functions after traumatic brain injury in a rat model","volume":"55","author":"Ling","year":"2024","journal-title":"J\u00a0Mol Histol"},{"issue":"44","key":"10.1016\/j.neurot.2024.e00515_bib112","doi-asserted-by":"crossref","first-page":"10262","DOI":"10.1523\/JNEUROSCI.2818-05.2005","article-title":"Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia","volume":"25","author":"Culmsee","year":"2005","journal-title":"J\u00a0Neurosci"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib113","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0306-4522(01)00461-4","article-title":"Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity","volume":"110","author":"Raghupathi","year":"2002","journal-title":"Neuroscience"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib114","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brainres.2006.10.032","article-title":"Apoptotic changes in the cortex and hippocampus following minimal brain trauma in mice","volume":"1130","author":"Tashlykov","year":"2007","journal-title":"Brain Res"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib115","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1089\/neu.1998.15.599","article-title":"Sustained sensory\/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouse","volume":"15","author":"Fox","year":"1998","journal-title":"J\u00a0Neurotrauma"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib116","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0165-0270(91)90104-8","article-title":"A\u00a0controlled cortical impact model of traumatic brain injury in the rat","volume":"39","author":"Dixon","year":"1991","journal-title":"J\u00a0Neurosci Methods"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib117","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1089\/neu.1992.9.11","article-title":"Cognitive deficits following traumatic brain injury produced by controlled cortical impact","volume":"9","author":"Hamm","year":"1992","journal-title":"J\u00a0Neurotrauma"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib118","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1096\/fasebj.13.8.813","article-title":"Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury","volume":"13","author":"Clark","year":"1999","journal-title":"Faseb J"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib119","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s004010000222","article-title":"TUNEL-positive staining of surface contusions after fatal head injury in man","volume":"100","author":"Smith","year":"2000","journal-title":"Acta Neuropathol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib120","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.bbadis.2009.09.002","article-title":"Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia","volume":"1802","author":"Niizuma","year":"2010","journal-title":"Biochim Biophys Acta"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib121","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/s41580-023-00629-4","article-title":"Mechanisms of BCL-2 family proteins in mitochondrial apoptosis","volume":"24","author":"Czabotar","year":"2023","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"Pt 19","key":"10.1016\/j.neurot.2024.e00515_bib122","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1242\/jcs.073643","article-title":"Regulation of the apaf-1-caspase-9 apoptosome","volume":"123","author":"Bratton","year":"2010","journal-title":"J\u00a0Cell Sci"},{"key":"10.1016\/j.neurot.2024.e00515_bib123","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2020.105143","article-title":"DNA damage and repair following traumatic brain injury","volume":"147","author":"Davis","year":"2021","journal-title":"Neurobiol Dis"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib124","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/01.WCB.0000080702.47016.FF","article-title":"Interaction between XIAP and Smac\/DIABLO in the mouse brain after transient focal cerebral ischemia","volume":"23","author":"Saito","year":"2003","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib125","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1471-4159.2002.00975.x","article-title":"Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite","volume":"82","author":"Zhang","year":"2002","journal-title":"J\u00a0Neurochem"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib126","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neulet.2005.05.058","article-title":"Early nuclear translocation of endonuclease G and subsequent DNA fragmentation after transient focal cerebral ischemia in mice","volume":"386","author":"Lee","year":"2005","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib127","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1096\/fj.08-111005","article-title":"Life and death by death receptors","volume":"23","author":"Guicciardi","year":"2009","journal-title":"Faseb J"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib128","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbcan.2020.188357","article-title":"Caspase-8: the double-edged sword","volume":"1873","author":"Mandal","year":"2020","journal-title":"Biochim Biophys Acta Rev Cancer"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib129","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1038\/sj.jcbfm.9600487","article-title":"TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice","volume":"27","author":"Bermpohl","year":"2007","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib130","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1006\/nbdi.2002.0482","article-title":"Akt phosphorylation and neuronal survival after traumatic brain injury in mice","volume":"9","author":"Noshita","year":"2002","journal-title":"Neurobiol Dis"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib131","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0304-3940(02)00866-2","article-title":"Potentiation of Akt and suppression of caspase-9 activations by electroacupuncture after transient middle cerebral artery occlusion in rats","volume":"331","author":"Wang","year":"2002","journal-title":"Neurosci Lett"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib132","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.expneurol.2012.07.004","article-title":"Interactions between SIRT1 and MAPK\/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo","volume":"237","author":"Zhao","year":"2012","journal-title":"Exp Neurol"},{"issue":"30","key":"10.1016\/j.neurot.2024.e00515_bib133","doi-asserted-by":"crossref","first-page":"7974","DOI":"10.1523\/JNEUROSCI.0897-06.2006","article-title":"Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats","volume":"26","author":"Endo","year":"2006","journal-title":"J\u00a0Neurosci"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib134","doi-asserted-by":"crossref","DOI":"10.1590\/1414-431x20177061","article-title":"Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression","volume":"51","author":"Du","year":"2018","journal-title":"Braz J Med Biol Res"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib135","doi-asserted-by":"crossref","first-page":"304","DOI":"10.7150\/ijms.49066","article-title":"FTY720 reduces endothelial cell apoptosis and remodels neurovascular unit after experimental traumatic brain injury","volume":"18","author":"Cheng","year":"2021","journal-title":"Int J Med Sci"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib136","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s10571-015-0227-1","article-title":"Traumatic brain injury-induced neuronal apoptosis is reduced through modulation of PI3K and autophagy pathways in mouse by FTY720","volume":"36","author":"Zhang","year":"2016","journal-title":"Cell Mol Neurobiol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib137","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/s12974-018-1345-8","article-title":"Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1","volume":"15","author":"Chen","year":"2018","journal-title":"J\u00a0Neuroinflammation"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib138","doi-asserted-by":"crossref","DOI":"10.1515\/tnsci-2022-0277","article-title":"Omega-3 polyunsaturated fatty acids alleviate early brain injury after traumatic brain injury by inhibiting neuroinflammation and necroptosis","volume":"14","author":"Wu","year":"2023","journal-title":"Transl Neurosci"},{"key":"10.1016\/j.neurot.2024.e00515_bib139","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.freeradbiomed.2014.03.009","article-title":"Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathway","volume":"71","author":"Xu","year":"2014","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.neurot.2024.e00515_bib140","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.3389\/fnins.2018.01006","article-title":"Baicalin protects mice brain from apoptosis in traumatic brain injury model through activation of autophagy","volume":"12","author":"Fang","year":"2018","journal-title":"Front Neurosci"},{"key":"10.1016\/j.neurot.2024.e00515_bib141","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.2147\/DDDT.S163951","article-title":"Baicalin provides neuroprotection in traumatic brain injury mice model through Akt\/Nrf2 pathway","volume":"12","author":"Fang","year":"2018","journal-title":"Drug Des Dev Ther"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib142","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2022.12732","article-title":"[Corrigendum] Quercetin protects rat cortical neurons against traumatic brain injury","volume":"26","author":"Du","year":"2022","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib143","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2014.01.051","article-title":"Neuroprotective and anti-apoptotic effects of valproic acid on adult rat cerebral cortex through ERK and Akt signaling pathway at acute phase of traumatic brain injury","volume":"1555","author":"Zhang","year":"2014","journal-title":"Brain Res"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib144","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0045763","article-title":"Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K\/Akt signaling after experimental traumatic brain injury","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neurot.2024.e00515_bib145","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2019.113135","article-title":"The p53 inactivators pifithrin-mu and pifithrin-alpha mitigate TBI-induced neuronal damage through regulation of oxidative stress, neuroinflammation, autophagy and mitophagy","volume":"324","author":"Yang","year":"2020","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neurot.2024.e00515_bib146","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.neuint.2015.06.003","article-title":"Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury","volume":"87","author":"Wei","year":"2015","journal-title":"Neurochem Int"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib147","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1097\/01.WCB.0000138664.17682.32","article-title":"Caspase inhibitor z-DEVD-fmk attenuates calpain and necrotic cell death in vitro and after traumatic brain injury","volume":"24","author":"Knoblach","year":"2004","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib148","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00004647-200404000-00007","article-title":"Caspase inhibitors prevent endothelial apoptosis and cerebral vasospasm in dog model of experimental subarachnoid hemorrhage","volume":"24","author":"Zhou","year":"2004","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib149","article-title":"Nrf2\/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation","volume":"7","author":"Wang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib150","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cbi.2017.04.021","article-title":"Mangiferin attenuates blast-induced traumatic brain injury via inhibiting NLRP3 inflammasome","volume":"271","author":"Fan","year":"2017","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.neurot.2024.e00515_bib151","doi-asserted-by":"crossref","DOI":"10.1038\/srep10344","article-title":"Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial","volume":"5","author":"Na","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib152","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.brainres.2015.01.003","article-title":"The reaction of cerebral cortex to a nearby lesion: damage, survival, self-protection","volume":"1601","author":"Purushothuman","year":"2015","journal-title":"Brain Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib153","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1471-2202-13-67","article-title":"Neuroglobin-overexpression reduces traumatic brain lesion size in mice","volume":"13","author":"Zhao","year":"2012","journal-title":"BMC Neurosci"},{"issue":"25","key":"10.1016\/j.neurot.2024.e00515_bib154","first-page":"1960","article-title":"Neuroglobin expression in rats after traumatic brain injury","volume":"7","author":"Lin","year":"2012","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib155","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.neuint.2017.07.012","article-title":"Recombinant neuroglobin ameliorates early brain injury after subarachnoid hemorrhage via inhibiting the activation of mitochondria apoptotic pathway","volume":"112","author":"Chen","year":"2018","journal-title":"Neurochem Int"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib156","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/cns.12655","article-title":"Mitochondrial dysfunction and biogenesis in neurodegenerative diseases: pathogenesis and treatment","volume":"23","author":"Golpich","year":"2017","journal-title":"CNS Neurosci Ther"},{"issue":"6098","key":"10.1016\/j.neurot.2024.e00515_bib157","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1126\/science.1219855","article-title":"Mitochondrial fission, fusion, and stress","volume":"337","author":"Youle","year":"2012","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib158","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.it.2017.08.006","article-title":"Mitochondrial dynamics at the interface of immune cell metabolism and function","volume":"39","author":"Rambold","year":"2018","journal-title":"Trends Immunol"},{"key":"10.1016\/j.neurot.2024.e00515_bib159","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.freeradbiomed.2017.08.003","article-title":"Mdivi-1 ameliorates early brain injury after subarachnoid hemorrhage via the suppression of inflammation-related blood-brain barrier disruption and endoplasmic reticulum stress-based apoptosis","volume":"112","author":"Fan","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.neurot.2024.e00515_bib160","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fnsys.2016.00029","article-title":"Altered mitochondrial dynamics and TBI pathophysiology","volume":"10","author":"Fischer","year":"2016","journal-title":"Front Syst Neurosci"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib161","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1038\/s41598-021-83545-x","article-title":"GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunction","volume":"11","author":"Xiao","year":"2021","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib162","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1152\/physiol.00038.2017","article-title":"Role of astrocytic mitochondria in limiting ischemic brain injury?","volume":"33","author":"Shih","year":"2018","journal-title":"Physiology"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib163","doi-asserted-by":"crossref","first-page":"9189","DOI":"10.1038\/s41598-017-09587-2","article-title":"Fusion or fission: the destiny of mitochondria in traumatic brain injury of different severities","volume":"7","author":"Di Pietro","year":"2017","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib164","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s11064-019-02916-z","article-title":"Mitophagy in the Hippocampus is excessive activated after cardiac arrest and cardiopulmonary resuscitation","volume":"45","author":"Huang","year":"2020","journal-title":"Neurochem Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib165","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2017.11.007","article-title":"Mdivi-1 alleviates blood-brain barrier disruption and cell death in experimental traumatic brain injury by mitigating autophagy dysfunction and mitophagy activation","volume":"94","author":"Wu","year":"2018","journal-title":"Int J Biochem Cell Biol"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib166","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/ncb2012","article-title":"PINK1\/Parkin-mediated mitophagy is dependent on VDAC1 and p62\/SQSTM1","volume":"12","author":"Geisler","year":"2010","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.neurot.2024.e00515_bib167","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2021.135967","article-title":"FUNDC1 inhibits NLRP3-mediated inflammation after intracerebral hemorrhage by promoting mitophagy in mice","volume":"756","author":"Zheng","year":"2021","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.neurot.2024.e00515_bib168","doi-asserted-by":"crossref","first-page":"e1090","DOI":"10.1016\/j.wneu.2018.10.236","article-title":"Mitochondrial division inhibitor 1 prevents early-stage induction of mitophagy and accelerated cell death in a rat model of moderate controlled cortical impact brain injury","volume":"122","author":"Niu","year":"2019","journal-title":"World Neurosurg"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib169","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/jnc.14962","article-title":"Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria","volume":"154","author":"Ren","year":"2020","journal-title":"J\u00a0Neurochem"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib170","doi-asserted-by":"crossref","first-page":"5211","DOI":"10.1111\/jcmm.14396","article-title":"Transplantation of mesenchymal stem cells overexpressing interleukin-10 induces autophagy response and promotes neuroprotection in a rat model of TBI","volume":"23","author":"Maiti","year":"2019","journal-title":"J\u00a0Cell Mol Med"},{"key":"10.1016\/j.neurot.2024.e00515_bib171","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.brainres.2019.01.005","article-title":"Rapamycin improves the neuroprotection effect of inhibition of NLRP3 inflammasome activation after TBI","volume":"1710","author":"Chen","year":"2019","journal-title":"Brain Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib172","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.niox.2020.02.001","article-title":"Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury","volume":"97","author":"Zakarya","year":"2020","journal-title":"Nitric Oxide"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib173","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/s41419-020-02836-9","article-title":"Dual effects of thyroid hormone on neurons and neurogenesis in traumatic brain injury","volume":"11","author":"Lin","year":"2020","journal-title":"Cell Death Dis"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib174","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1523\/JNEUROSCI.3415-17.2018","article-title":"Cardiolipin-dependent mitophagy guides outcome after traumatic brain injury","volume":"39","author":"Chao","year":"2019","journal-title":"J\u00a0Neurosci"},{"issue":"13","key":"10.1016\/j.neurot.2024.e00515_bib175","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23136924","article-title":"Therapeutic effect of mitochondrial division inhibitor-1 (Mdivi-1) on hyperglycemia-exacerbated early and delayed brain injuries after experimental subarachnoid hemorrhage","volume":"23","author":"Chung","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.neurot.2024.e00515_bib176","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.brainres.2015.11.016","article-title":"Mitochondrial division inhibitor 1 (Mdivi-1) offers neuroprotection through diminishing cell death and improving functional outcome in a mouse model of traumatic brain injury","volume":"1630","author":"Wu","year":"2016","journal-title":"Brain Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib177","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2021.778569","article-title":"Effects of mdivi-1 on neural mitochondrial dysfunction and mitochondria-mediated apoptosis in ischemia-reperfusion injury after stroke: a systematic review of preclinical studies","volume":"14","author":"Nhu","year":"2021","journal-title":"Front Mol Neurosci"},{"issue":"24","key":"10.1016\/j.neurot.2024.e00515_bib178","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000011119","article-title":"Rapamycin treatment for amyotrophic lateral sclerosis: protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial)","volume":"97","author":"Mandrioli","year":"2018","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.neurot.2024.e00515_bib179","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuroscience.2023.11.022","article-title":"Celastrol alleviates mitochondrial oxidative stress and brain injury after intracerebral hemorrhage by promoting OPA1-dependent mitochondrial fusion","volume":"536","author":"Diao","year":"2024","journal-title":"Neuroscience"},{"key":"10.1016\/j.neurot.2024.e00515_bib180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41016-019-0182-7","article-title":"SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner","volume":"6","author":"Wu","year":"2020","journal-title":"Chin Neurosurg J"},{"issue":"12","key":"10.1016\/j.neurot.2024.e00515_bib181","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1007\/s12031-022-02089-5","article-title":"Honokiol reduces mitochondrial dysfunction and inhibits apoptosis of nerve cells in rats with traumatic brain injury by activating the mitochondrial unfolded protein response","volume":"72","author":"Sun","year":"2022","journal-title":"J\u00a0Mol Neurosci"},{"issue":"11","key":"10.1016\/j.neurot.2024.e00515_bib182","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.4103\/1673-5374.339002","article-title":"Human umbilical cord-derived mesenchymal stem cells promote repair of neonatal brain injury caused by hypoxia\/ischemia in rats","volume":"17","author":"Jiao","year":"2022","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.neurot.2024.e00515_bib183","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1146\/annurev-pharmtox-010716-104908","article-title":"Repairing mitochondrial dysfunction in disease","volume":"58","author":"Sorrentino","year":"2018","journal-title":"Annu Rev Pharmacol Toxicol"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib184","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1007\/s11064-023-03934-8","article-title":"The role of PGC-1alpha-mediated mitochondrial biogenesis in neurons","volume":"48","author":"Chen","year":"2023","journal-title":"Neurochem Res"},{"issue":"23","key":"10.1016\/j.neurot.2024.e00515_bib185","doi-asserted-by":"crossref","first-page":"10411","DOI":"10.1021\/acs.jmedchem.6b00669","article-title":"Development of therapeutics that induce mitochondrial biogenesis for the treatment of acute and chronic degenerative diseases","volume":"59","author":"Cameron","year":"2016","journal-title":"J\u00a0Med Chem"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib186","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/cvr\/cvn098","article-title":"Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha","volume":"79","author":"Ventura-Clapier","year":"2008","journal-title":"Cardiovasc Res"},{"issue":"7","key":"10.1016\/j.neurot.2024.e00515_bib187","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1210\/er.2006-0037","article-title":"Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism","volume":"27","author":"Handschin","year":"2006","journal-title":"Endocr Rev"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib188","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1124\/jpet.117.244806","article-title":"Mitochondrial-based therapeutics for the treatment of spinal cord injury: mitochondrial biogenesis as a potential pharmacological target","volume":"363","author":"Scholpa","year":"2017","journal-title":"J\u00a0Pharmacol Exp Therapeut"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib189","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.3109\/02699052.2012.672789","article-title":"The expression of PGC-1alpha in the mice brain after traumatic brain injury","volume":"26","author":"Fan","year":"2012","journal-title":"Brain Inj"},{"issue":"10","key":"10.1016\/j.neurot.2024.e00515_bib190","doi-asserted-by":"crossref","first-page":"5289","DOI":"10.1007\/s12035-021-02487-7","article-title":"Defective autophagy and mitophagy in Alzheimer's disease: mechanisms and translational implications","volume":"58","author":"Chen","year":"2021","journal-title":"Mol Neurobiol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib191","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/jnc.13726","article-title":"Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcome","volume":"139","author":"Hill","year":"2016","journal-title":"J\u00a0Neurochem"},{"key":"10.1016\/j.neurot.2024.e00515_bib192","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2024.110870","article-title":"Activation of the melanocortin-1 receptor attenuates neuronal apoptosis after traumatic brain injury by upregulating Merlin expression","volume":"207","author":"Lu","year":"2024","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neurot.2024.e00515_bib193","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-021-02078-2","article-title":"Activation of MC1R with BMS-470539 attenuates neuroinflammation via cAMP\/PKA\/Nurr1 pathway after neonatal hypoxic-ischemic brain injury in rats","volume":"18","author":"Yu","year":"2021","journal-title":"J\u00a0Neuroinflammation"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib194","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0031739","article-title":"Overexpression of mitochondrial uncoupling protein 2 inhibits inflammatory cytokines and activates cell survival factors after cerebral ischemia","volume":"7","author":"Haines","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.neurot.2024.e00515_bib195","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/1118981","article-title":"Irisin rescues blood-brain barrier permeability following traumatic brain injury and contributes to the neuroprotection of exercise in traumatic brain injury","volume":"2021","author":"Guo","year":"2021","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib196","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12974-022-02438-6","article-title":"Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin alphaVbeta5\/AMPK signaling pathway after intracerebral hemorrhage in mice","volume":"19","author":"Wang","year":"2022","journal-title":"J\u00a0Neuroinflammation"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib197","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1002\/med.21565","article-title":"Health benefits of resveratrol: evidence from clinical studies","volume":"39","author":"Singh","year":"2019","journal-title":"Med Res Rev"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib198","doi-asserted-by":"crossref","first-page":"522","DOI":"10.7150\/thno.49426","article-title":"Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK\/SIRT1\/PGC-1\u03b1 pathway in rats","volume":"11","author":"Xu","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.neurot.2024.e00515_bib199","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.101856","article-title":"Heat shock protein 22 modulates NRF1\/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1alpha signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats","volume":"40","author":"Fan","year":"2021","journal-title":"Redox Biol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib200","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11064-018-2588-6","article-title":"A\u00a0ketogenic diet improves mitochondrial biogenesis and bioenergetics via the PGC1alpha-SIRT3-UCP2 Axis","volume":"44","author":"Hasan-Olive","year":"2019","journal-title":"Neurochem Res"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib201","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1038\/nm903","article-title":"Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma","volume":"9","author":"Mattiasson","year":"2003","journal-title":"Nat Med"},{"key":"10.1016\/j.neurot.2024.e00515_bib202","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2018.02.017","article-title":"Serum levels of irisin predict short-term outcomes in ischemic stroke","volume":"122","author":"Wu","year":"2019","journal-title":"Cytokine"},{"key":"10.1016\/j.neurot.2024.e00515_bib203","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2020.113310","article-title":"Microglia and macrophage metabolism in CNS injury and disease: the role of immunometabolism in neurodegeneration and neurotrauma","volume":"329","author":"Devanney","year":"2020","journal-title":"Exp Neurol"},{"key":"10.1016\/j.neurot.2024.e00515_bib204","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2019.134347","article-title":"Mitochondrial dysfunctioning and neuroinflammation: recent highlights on the possible mechanisms involved in Traumatic Brain Injury","volume":"710","author":"Kumar Sahel","year":"2019","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib205","doi-asserted-by":"crossref","first-page":"195","DOI":"10.15698\/cst2019.06.190","article-title":"The sensing of mitochondrial DAMPs by non-immune cells","volume":"3","author":"Rodriguez-Nuevo","year":"2019","journal-title":"Cell Stress"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib206","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/s41577-022-00760-x","article-title":"Mitochondrial control of inflammation","volume":"23","author":"Marchi","year":"2023","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.neurot.2024.e00515_bib207","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.633610","article-title":"The role of NF-kappaB triggered inflammation in cerebral ischemia","volume":"15","author":"Jover-Mengual","year":"2021","journal-title":"Front Cell Neurosci"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib208","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1476-5381.2012.02025.x","article-title":"Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies","volume":"167","author":"Cheng","year":"2012","journal-title":"Br J Pharmacol"},{"issue":"0 3","key":"10.1016\/j.neurot.2024.e00515_bib209","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.expneurol.2015.08.018","article-title":"Microglia in the TBI brain: the good, the bad, and the dysregulated","volume":"275 Pt 3","author":"Loane","year":"2016","journal-title":"Exp Neurol"},{"issue":"6477","key":"10.1016\/j.neurot.2024.e00515_bib210","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1126\/science.aax6752","article-title":"Microglia monitor and protect neuronal function through specialized somatic purinergic junctions","volume":"367","author":"Cserep","year":"2020","journal-title":"Science"},{"issue":"7638","key":"10.1016\/j.neurot.2024.e00515_bib211","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.neurot.2024.e00515_bib212","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22126418","article-title":"Pathophysiological responses and roles of astrocytes in traumatic brain injury","volume":"22","author":"Michinaga","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.neurot.2024.e00515_bib213","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.3389\/fimmu.2018.01605","article-title":"Diverse roles of mitochondria in immune responses: novel insights into immuno-metabolism","volume":"9","author":"Angajala","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.neurot.2024.e00515_bib214","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1266973","article-title":"Succinate metabolism: a promising therapeutic target for inflammation, ischemia\/reperfusion injury and cancer","volume":"11","author":"Zhang","year":"2023","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.neurot.2024.e00515_bib215","article-title":"Cellular succinate metabolism and signaling in inflammation: implications for therapeutic intervention","volume":"15","author":"Huang","year":"2024","journal-title":"Front Immunol"},{"key":"10.1016\/j.neurot.2024.e00515_bib216","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.molmet.2019.11.019","article-title":"Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury","volume":"32","author":"Cordes","year":"2020","journal-title":"Mol Metabol"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib217","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/jnc.15959","article-title":"Fundamental Neurochemistry Review: microglial immunometabolism in traumatic brain injury","volume":"167","author":"Strogulski","year":"2023","journal-title":"J\u00a0Neurochem"},{"key":"10.1016\/j.neurot.2024.e00515_bib218","article-title":"Mesenchymal stem\/stromal cell-mediated mitochondrial transfer and the therapeutic potential in treatment of neurological diseases","volume":"2020","author":"Han","year":"2020","journal-title":"Stem Cell Int"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib219","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001166","article-title":"Neural stem cells traffic functional mitochondria via extracellular vesicles","volume":"19","author":"Peruzzotti-Jametti","year":"2021","journal-title":"PLoS Biol"},{"key":"10.1016\/j.neurot.2024.e00515_bib220","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.brainres.2019.04.003","article-title":"Morin post-treatment confers neuroprotection in a novel rat model of mild repetitive traumatic brain injury by targeting dementia markers, APOE, autophagy and Wnt\/beta-catenin signaling pathway","volume":"1717","author":"El-Gazar","year":"2019","journal-title":"Brain Res"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib221","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1161\/STROKEAHA.115.009099","article-title":"Mitochondrial crisis in cerebrovascular endothelial cells opens the blood-brain barrier","volume":"46","author":"Doll","year":"2015","journal-title":"Stroke"},{"issue":"suppl 2","key":"10.1016\/j.neurot.2024.e00515_bib222","article-title":"Deciphering the blood-brain barrier damage in stroke: mitochondrial mechanism","volume":"6","author":"Ren","year":"2015","journal-title":"J\u00a0Neuroinfect Dis"},{"key":"10.1016\/j.neurot.2024.e00515_bib223","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbi.2014.08.007","article-title":"The blood-brain barrier in neuroimmunology: tales of separation and assimilation","volume":"44","author":"Banks","year":"2015","journal-title":"Brain Behav Immun"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib224","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1182\/blood-2009-12-257832","article-title":"Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction","volume":"116","author":"Fantin","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.neurot.2024.e00515_bib225","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.mito.2023.01.007","article-title":"Mitochondrial oxidative stress in brain microvascular endothelial cells: triggering blood-brain barrier disruption","volume":"69","author":"Wang","year":"2023","journal-title":"Mitochondrion"},{"issue":"6","key":"10.1016\/j.neurot.2024.e00515_bib226","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s11011-020-00573-8","article-title":"Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke","volume":"35","author":"Sarvari","year":"2020","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.neurot.2024.e00515_bib227","series-title":"Translational research in traumatic brain injury","article-title":"Blood-brain barrier pathophysiology following traumatic brain injury","author":"Price","year":"2016"},{"issue":"4","key":"10.1016\/j.neurot.2024.e00515_bib228","article-title":"Uncoupling of the electron transport chain compromises mitochondrial oxidative phosphorylation and exacerbates stroke outcomes","volume":"9","author":"Grasmick","year":"2018","journal-title":"J\u00a0Neuroinfect Dis"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib229","doi-asserted-by":"crossref","first-page":"14","DOI":"10.14336\/AD.2015.0906","article-title":"Mitochondrial impairment in cerebrovascular endothelial cells is involved in the correlation between body temperature and stroke severity","volume":"7","author":"Hu","year":"2016","journal-title":"Aging Dis"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib230","doi-asserted-by":"crossref","first-page":"9990","DOI":"10.1038\/s41598-023-36993-6","article-title":"A\u00a0novel specific aptamer targets cerebrovascular endothelial cells after ischemic stroke","volume":"13","author":"Hu","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.neurot.2024.e00515_bib231","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1278334","article-title":"Role of microRNA-34a in blood-brain barrier permeability and mitochondrial function in ischemic stroke","volume":"17","author":"Payne","year":"2023","journal-title":"Front Cell Neurosci"},{"issue":"2","key":"10.1016\/j.neurot.2024.e00515_bib232","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/0271678X15606147","article-title":"MiR-34a regulates blood-brain barrier permeability and mitochondrial function by targeting cytochrome c","volume":"36","author":"Bukeirat","year":"2016","journal-title":"J\u00a0Cerebr Blood Flow Metabol"},{"key":"10.1016\/j.neurot.2024.e00515_bib233","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neuint.2018.10.019","article-title":"MiR-34a and stroke: assessment of non-modifiable biological risk factors in cerebral ischemia","volume":"127","author":"Ren","year":"2019","journal-title":"Neurochem Int"},{"key":"10.1016\/j.neurot.2024.e00515_bib234","doi-asserted-by":"crossref","first-page":"2950","DOI":"10.12659\/MSM.900237","article-title":"Increased expression of mir-34a-5p and clinical association in acute ischemic stroke patients and in a rat model","volume":"22","author":"Liang","year":"2016","journal-title":"Med Sci Monit"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib235","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1038\/s41598-020-59997-y","article-title":"MiR-34a interacts with cytochrome c and shapes stroke outcomes","volume":"10","author":"Hu","year":"2020","journal-title":"Sci Rep"},{"issue":"66","key":"10.1016\/j.neurot.2024.e00515_bib236","doi-asserted-by":"crossref","first-page":"110209","DOI":"10.18632\/oncotarget.22597","article-title":"MicroRNA-34a promotes mitochondrial dysfunction-induced apoptosis in human lens epithelial cells by targeting Notch2","volume":"8","author":"Fan","year":"2017","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib237","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1002\/anie.201915826","article-title":"Smart design of nanomaterials for mitochondria-targeted nanotherapeutics","volume":"60","author":"Liew","year":"2021","journal-title":"Angew Chem Int Ed Engl"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib238","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.expneurol.2011.09.028","article-title":"Polymer and nano-technology applications for repair and reconstruction of the central nervous system","volume":"233","author":"Cho","year":"2012","journal-title":"Exp Neurol"},{"issue":"8","key":"10.1016\/j.neurot.2024.e00515_bib239","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1016\/j.apsb.2020.11.023","article-title":"Evolution of blood-brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies","volume":"11","author":"Han","year":"2021","journal-title":"Acta Pharm Sin B"},{"key":"10.1016\/j.neurot.2024.e00515_bib240","article-title":"Mitochondria-targeted delocalized lipophilic cation complexed with human serum albumin for tumor cell imaging and treatment","volume":"23","author":"Qian","year":"2020","journal-title":"Nanomedicine"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib241","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1080\/10717544.2020.1745328","article-title":"Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems","volume":"27","author":"Han","year":"2020","journal-title":"Drug Deliv"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib242","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12951-019-0451-9","article-title":"Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats","volume":"17","author":"Zhang","year":"2019","journal-title":"J\u00a0Nanobiotechnol"},{"issue":"9","key":"10.1016\/j.neurot.2024.e00515_bib243","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202006570","article-title":"Biomimetic design of mitochondria-targeted hybrid nanozymes as superoxide scavengers","volume":"33","author":"Zhang","year":"2021","journal-title":"Adv Mater"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib244","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abd6889","article-title":"BBB pathophysiology-independent delivery of siRNA in traumatic brain injury","volume":"7","author":"Li","year":"2021","journal-title":"Sci Adv"},{"issue":"3","key":"10.1016\/j.neurot.2024.e00515_bib245","article-title":"Intraarterial transplantation of mitochondria after ischemic stroke reduces cerebral infarction","volume":"3","author":"Norat","year":"2023","journal-title":"Stroke Vasc Interv Neurol"},{"issue":"1","key":"10.1016\/j.neurot.2024.e00515_bib246","doi-asserted-by":"crossref","first-page":"4078","DOI":"10.1038\/s41467-020-17930-x","article-title":"Blood substitution therapy rescues the brain of mice from ischemic damage","volume":"11","author":"Ren","year":"2020","journal-title":"Nat Commun"},{"issue":"14","key":"10.1016\/j.neurot.2024.e00515_bib247","doi-asserted-by":"crossref","first-page":"6661","DOI":"10.1021\/jacs.0c00188","article-title":"Design of a functionalized metal-organic framework system for enhanced targeted delivery to mitochondria","volume":"142","author":"Haddad","year":"2020","journal-title":"J\u00a0Am Chem Soc"},{"issue":"5","key":"10.1016\/j.neurot.2024.e00515_bib248","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e09394","article-title":"Liposomes: structure, composition, types, and clinical applications","volume":"8","author":"Nsairat","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.neurot.2024.e00515_bib249","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4103\/ijpvm.ijpvm_441_21","article-title":"Safety of intraparenchymal injection of allogenic placenta mesenchymal stem cells derived exosome in patients undergoing decompressive craniectomy following malignant middle cerebral artery infarct, A pilot randomized clinical trial","volume":"13","author":"Dehghani","year":"2022","journal-title":"Int J Prev Med"}],"container-title":["Neurotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747924002022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747924002022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:26:48Z","timestamp":1740122808000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878747924002022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":249,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S1878747924002022"],"URL":"https:\/\/doi.org\/10.1016\/j.neurot.2024.e00515","relation":{},"ISSN":["1878-7479"],"issn-type":[{"value":"1878-7479","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside","name":"articletitle","label":"Article Title"},{"value":"Neurotherapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurot.2024.e00515","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics.","name":"copyright","label":"Copyright"}],"article-number":"e00515"}}