{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:31:24Z","timestamp":1784547084410,"version":"3.55.0"},"reference-count":95,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS100874"],"award-info":[{"award-number":["R01NS100874"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS127435"],"award-info":[{"award-number":["R01NS127435"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS119301"],"award-info":[{"award-number":["R01NS119301"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["K08NS121600"],"award-info":[{"award-number":["K08NS121600"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["P50HD103555"],"award-info":[{"award-number":["P50HD103555"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["neurotherapeuticsjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotherapeutics"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.neurot.2025.e00543","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T17:26:55Z","timestamp":1739381215000},"page":"e00543","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Thalamic deep brain stimulation improves movement in a cerebellar model of lesion-based status dystonicus"],"prefix":"10.1016","volume":"22","author":[{"given":"Megan X.","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda M.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy V.","family":"Sillitoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason S.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.neurot.2025.e00543_bib1","article-title":"Dystonia","volume":"4","author":"Balint","year":"2018","journal-title":"Nat Rev Dis Prim"},{"key":"10.1016\/j.neurot.2025.e00543_bib2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1468-1331.2010.03053.x","article-title":"The epidemiology of primary dystonia: current evidence and perspectives","volume":"17","author":"Defazio","year":"2010","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib3","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/mds.25475","article-title":"Phenomenology and classification of dystonia: a consensus update","volume":"28","author":"Albanese","year":"2013","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/brain\/121.2.243","article-title":"Status dystonicus: the syndrome and its management","volume":"121","author":"Manji","year":"1998","journal-title":"Brain"},{"key":"10.1016\/j.neurot.2025.e00543_bib5","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1002\/mds.29794","article-title":"Recommendations for the management of initial and refractory pediatric status dystonicus","volume":"39","author":"Vogt","year":"2024","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib6","doi-asserted-by":"crossref","first-page":"105438","DOI":"10.1016\/j.parkreldis.2023.105438","article-title":"The changing face of reported status dystonicus \u2013 a systematic review","volume":"112","author":"Lumsden","year":"2023","journal-title":"Park Relat Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib7","series-title":"Cerebellar deep brain stimulation for acquired hemidystonia.","first-page":"188","volume":"vol. 7","author":"Brown","year":"2020"},{"key":"10.1016\/j.neurot.2025.e00543_bib8","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/ene.13255","article-title":"Efficacy of pallidal stimulation in isolated dystonia: a systematic review and meta-analysis","volume":"24","author":"Moro","year":"2017","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib9","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1038\/nrneurol.2015.86","article-title":"Dopa-responsive dystonia - clinical and genetic heterogeneity","volume":"11","author":"Wijemanne","year":"2015","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib10","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/PHM.0000000000002099","article-title":"Impact of cerebellar injury on neurodevelopmental outcomes in preterm infants with cerebral palsy","volume":"102","author":"Kim","year":"2023","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.neurot.2025.e00543_bib11","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000201042","article-title":"Clinical and structural findings in patients with lesion-induced dystonia: descriptive and quantitative analysis of published cases","author":"Corp","year":"2022","journal-title":"Neurology"},{"key":"10.1016\/j.neurot.2025.e00543_bib12","doi-asserted-by":"crossref","first-page":"E645","DOI":"10.1212\/CPJ.0000000000000989","article-title":"Pediatric dystonic storm","volume":"11","author":"Goswami","year":"2021","journal-title":"Neurol Clin Pract"},{"key":"10.1016\/j.neurot.2025.e00543_bib13","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/mds.24981","article-title":"Status dystonicus: predictors of outcome and progression patterns of underlying disease","volume":"27","author":"Fasano","year":"2012","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib14","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1177\/08830738221081593","article-title":"Status dystonicus in children: a cross-sectional study and review of literature","volume":"37","author":"Saini","year":"2022","journal-title":"J\u00a0Child Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib15","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1097\/MOP.0000000000000556","article-title":"Status dystonicus in childhood","volume":"29","author":"Lumsden","year":"2017","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.neurot.2025.e00543_bib16","doi-asserted-by":"crossref","first-page":"E1957","DOI":"10.1212\/WNL.0000000000201042","article-title":"Clinical and structural findings in patients with lesion-induced dystonia: descriptive and quantitative analysis of published cases","volume":"99","author":"Corp","year":"2022","journal-title":"Neurology"},{"key":"10.1016\/j.neurot.2025.e00543_bib17","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/mds.10301","article-title":"Secondary cervical dystonia associated with structural lesions of the central nervous system","volume":"18","author":"LeDoux","year":"2003","journal-title":"Mov Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/0883073809338067","article-title":"Cerebellum of the premature infant : rapidly developing , vulnerable , clinically important","volume":"24","author":"Volpe","year":"2009","journal-title":"J\u00a0Child Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib19","first-page":"2018","article-title":"Functional connectivity alterations in children with spastic and dyskinetic cerebral palsy","author":"Qin","year":"2018","journal-title":"Neural Plast"},{"key":"10.1016\/j.neurot.2025.e00543_bib20","doi-asserted-by":"crossref","DOI":"10.1038\/s41583-019-0152-2","article-title":"Emerging connections between cerebellar development, behaviour and complex brain disorders","volume":"20","author":"Sathyanesan","year":"2019","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib21","doi-asserted-by":"crossref","unstructured":"Gilbert LA, Gandham S, Ueda K, K. Chintalapati, T. Pearson, B.R Aravamuthan. Upper extremity dystonia features in people with spastic cerebral palsy. 2023.","DOI":"10.1212\/CPJ.0000000000200207"},{"key":"10.1016\/j.neurot.2025.e00543_bib22","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.ejpn.2017.04.1333","article-title":"Spasticity, dyskinesia and ataxia in cerebral palsy: are we sure we can differentiate them?","volume":"21","author":"Eggink","year":"2017","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib23","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/brain\/awz112","article-title":"Network localization of cervical dystonia based on causal brain lesions","volume":"142","author":"Corp","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.neurot.2025.e00543_bib24","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1007\/s00221-020-05863-2","article-title":"Delineating the electrophysiological signature of dystonia","volume":"238","author":"Latorre","year":"2020","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neurot.2025.e00543_bib25","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5334\/tohm.383","article-title":"The anatomical basis for dystonia: the motor network model","volume":"7","author":"Jinnah","year":"2017","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"10.1016\/j.neurot.2025.e00543_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s12311-016-0825-6","article-title":"Current opinions and areas of consensus on the role of the cerebellum in dystonia","volume":"16","author":"Shakkottai","year":"2017","journal-title":"Cerebellum"},{"key":"10.1016\/j.neurot.2025.e00543_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fncel.2019.00441","article-title":"Functional outcomes of cerebellar malformations","volume":"13","author":"Gill","year":"2019","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib28","doi-asserted-by":"crossref","DOI":"10.1007\/s12311-022-01441-0","article-title":"Cerebellar dysfunction as a source of dystonic phenotypes in mice","author":"Brown","year":"2022","journal-title":"Cerebellum"},{"key":"10.1016\/j.neurot.2025.e00543_bib29","article-title":"Altered dendritic morphology of Purkinje cells in Dyt1 \u0394GAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice","author":"Zhang","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.neurot.2025.e00543_bib30","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.22775","article-title":"A\u00a0role for cerebellum in the hereditary dystonia DYT1","volume":"6","author":"Fremont","year":"2017","journal-title":"Elife"},{"key":"10.1016\/j.neurot.2025.e00543_bib31","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1172\/JCI72830","article-title":"TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration","volume":"124","author":"Liang","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.neurot.2025.e00543_bib32","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00221-002-1127-4","article-title":"Abnormal spontaneous and harmaline-stimulated Purkinje cell activity in the awake genetically dystonic rat","volume":"145","author":"Ledoux","year":"2002","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.neurot.2025.e00543_bib33","doi-asserted-by":"crossref","first-page":"11723","DOI":"10.1523\/JNEUROSCI.1409-14.2014","article-title":"Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism","volume":"34","author":"Fremont","year":"2014","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib34","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nn.2753","article-title":"The neural substrates of rapid-onset Dystonia-Parkinsonism","volume":"14","author":"Calderon","year":"2011","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib35","doi-asserted-by":"crossref","first-page":"7825","DOI":"10.1523\/JNEUROSCI.22-17-07825.2002","article-title":"Abnormal cerebellar signaling induces dystonia in mice","volume":"22","author":"Pizoli","year":"2002","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14912","article-title":"Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice","volume":"8","author":"White","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.neurot.2025.e00543_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/dyst.2022.10494","article-title":"Quantification of behavioral deficits in developing mice with dystonic behaviors","volume":"1","author":"Van Der Heijden","year":"2022","journal-title":"Dystonia"},{"issue":"6","key":"10.1016\/j.neurot.2025.e00543_bib38","article-title":"Cerebellar deep brain stimulation as a dual-function therapeutic for restoring movement and sleep in dystonic mice","volume":"21","author":"Leon","year":"2024","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.neurot.2025.e00543_bib39","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1056\/NEJMoa063618","article-title":"Pallidal deep-brain stimulation in primary generalized or segmental dystonia","volume":"355","author":"Kupsch","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.neurot.2025.e00543_bib40","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S1474-4422(14)70143-7","article-title":"Pallidal neurostimulation in patients with medication-refractory cervical dystonia: a randomised, sham-controlled trial","volume":"13","author":"Volkmann","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib41","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00702-016-1656-9","article-title":"Deep brain stimulation for dystonia: a novel perspective on the value of genetic testing","volume":"124","author":"Jinnah","year":"2017","journal-title":"J\u00a0Neural Transm"},{"key":"10.1016\/j.neurot.2025.e00543_bib42","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.parkreldis.2022.02.001","article-title":"A\u00a0randomised double-blind controlled study of Deep Brain Stimulation for dystonia in STN or GPi - a long term follow-up after up to 15 years","volume":"96","author":"H\u00f8ck","year":"2022","journal-title":"Parkinsonism Relat Disorders"},{"key":"10.1016\/j.neurot.2025.e00543_bib43","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000524577","article-title":"Long-term outcomes of deep brain stimulation for pediatric dystonia","volume":"57","author":"Malatt","year":"2022","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.neurot.2025.e00543_bib44","doi-asserted-by":"crossref","first-page":"209","DOI":"10.5535\/arm.2014.38.2.209","article-title":"Two-Year outcomes of deep brain stimulation in adults with cerebral palsy","volume":"38","author":"Kim","year":"2014","journal-title":"Ann Rehabil Med"},{"key":"10.1016\/j.neurot.2025.e00543_bib45","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3171\/2020.7.PEDS20348","article-title":"Thalamic deep brain stimulation for acquired dystonia in children and young adults: a phase 1 clinical trial","volume":"27","author":"Luciano","year":"2021","journal-title":"J\u00a0Neurosurg Pediatr"},{"key":"10.1016\/j.neurot.2025.e00543_bib46","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.parkreldis.2019.01.029","article-title":"Deep brain stimulation for dystonia-choreoathetosis in cerebral palsy: pallidal versus thalamic stimulation","volume":"63","author":"Wolf","year":"2019","journal-title":"Park Relat Disord"},{"key":"10.1016\/j.neurot.2025.e00543_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/life11080776","article-title":"Dystonia and cerebellum: from bench to bedside","volume":"11","author":"Morigaki","year":"2021","journal-title":"Life"},{"key":"10.1016\/j.neurot.2025.e00543_bib48","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.neuchi.2020.04.132","article-title":"Dentate nucleus as target for deep brain stimulation in dystono-dyskinetic syndromes","volume":"66","author":"Nicholson","year":"2020","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.neurot.2025.e00543_bib49","first-page":"712","article-title":"The striking effects of deep cerebellar stimulation on generalized fixed dystonia: case report","volume":"132","author":"Horisawa","year":"2020","journal-title":"J\u00a0Neurosurg"},{"key":"10.1016\/j.neurot.2025.e00543_bib50","first-page":"1","article-title":"High frequency deep brain stimulation of superior cerebellar peduncles in a patient with cerebral palsy","volume":"10","author":"Lin","year":"2020","journal-title":"Tremor Other Hyperkinet Mov"},{"key":"10.1016\/j.neurot.2025.e00543_bib51","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.clineuro.2015.05.017","article-title":"Deep anterior cerebellar stimulation reduces symptoms of secondary dystonia in patients with cerebral palsy treated due to spasticity","volume":"135","author":"Sokal","year":"2015","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.neurot.2025.e00543_bib52","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.26799","article-title":"Deep brain stimulation for refractory status dystonicus in children: multicenter case series and systematic review","volume":"95","author":"Vogt","year":"2024","journal-title":"Ann Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib53","doi-asserted-by":"crossref","first-page":"9740","DOI":"10.1523\/JNEUROSCI.2300-09.2009","article-title":"Cerebellothalamocortical connectivity regulates penetrance in dystonia","volume":"29","author":"Argyelan","year":"2009","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.0000000000008326","article-title":"Pediatric postoperative cerebellar cognitive affective syndrome follows out flow pathway lesions","volume":"93","author":"Albazron","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/j.neurot.2025.e00543_bib55","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/147342202753203104","article-title":"Cerebello-thalamic synapses and motor adaptation","volume":"1","author":"Aumann","year":"2002","journal-title":"Cerebellum"},{"key":"10.1016\/j.neurot.2025.e00543_bib56","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/cne.901780402","article-title":"Projections of the superior cerebellar peduncle in rats and the development of new connections in response to neonatal hemicerebellectomy","volume":"178","author":"Castro","year":"1978","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib57","doi-asserted-by":"crossref","DOI":"10.1007\/s12311-021-01264-5","article-title":"Epigenetic regulation of neural transmission after cerebellar fastigial nucleus lesions in juvenile rats","author":"Helgers","year":"2021","journal-title":"Cerebellum"},{"key":"10.1016\/j.neurot.2025.e00543_bib58","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neuroscience.2020.06.035","article-title":"Lesion of the fastigial nucleus in juvenile rats deteriorates rat behavior in adulthood, accompanied by altered neuronal activity in the medial prefrontal cortex","volume":"442","author":"Helgers","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.neurot.2025.e00543_bib59","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1007\/s00429-019-01871-3","article-title":"Long-term impairment of social behavior, vocalizations and motor activity induced by bilateral lesions of the fastigial nucleus in juvenile rats","volume":"224","author":"Al-Afif","year":"2019","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.neurot.2025.e00543_bib60","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuroscience.2013.11.062","article-title":"Dystonia as a network disorder: what is the role of the cerebellum?","volume":"260","author":"Prudente","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.neurot.2025.e00543_bib61","doi-asserted-by":"crossref","first-page":"8231","DOI":"10.1523\/JNEUROSCI.0122-14.2014","article-title":"Cerebellar zonal patterning relies on Purkinje cell neurotransmission","volume":"34","author":"White","year":"2014","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib62","doi-asserted-by":"crossref","first-page":"12150","DOI":"10.1523\/JNEUROSCI.2059-08.2008","article-title":"Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum","volume":"28","author":"Sillitoe","year":"2008","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnana.2013.00009","article-title":"Postnatal development of cerebellar zones revealed by neurofilament heavy chain protein expression","volume":"7","author":"White","year":"2013","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.neurot.2025.e00543_bib64","doi-asserted-by":"crossref","first-page":"10015","DOI":"10.1523\/JNEUROSCI.0653-10.2010","article-title":"Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map","volume":"30","author":"Sillitoe","year":"2010","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-21417-8","article-title":"Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia","volume":"12","author":"Miterko","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.neurot.2025.e00543_bib66","series-title":"The mouse brain in stereotaxic coordinates","author":"Paxinos","year":"2001"},{"key":"10.1016\/j.neurot.2025.e00543_bib67","first-page":"1","article-title":"Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice","author":"Salazar-Leon","year":"2023","journal-title":"Dystonia"},{"key":"10.1016\/j.neurot.2025.e00543_bib68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.51928","article-title":"Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation","volume":"9","author":"Brown","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.neurot.2025.e00543_bib69","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jneumeth.2016.01.010","article-title":"An optimized surgical approach for obtaining stable extracellular single-unit recordings from the cerebellum of head-fixed behaving mice","volume":"262","author":"White","year":"2016","journal-title":"J\u00a0Neurosci Methods"},{"key":"10.1016\/j.neurot.2025.e00543_bib70","first-page":"1","article-title":"Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors","author":"Van Der Heijden","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.neurot.2025.e00543_bib71","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1152\/jn.1996.75.5.1806","article-title":"Comparison of discharge variability in vitro and in vivo in cat visual cortex neurons","volume":"75","author":"Holt","year":"1996","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.neurot.2025.e00543_bib72","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/brain\/awx317","article-title":"The cerebellar cognitive affective\/Schmahmann syndrome scale","volume":"141","author":"Hoche","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.neurot.2025.e00543_bib73","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/WCO.0000000000000580","article-title":"Dystonia as a network disorder: a concept in evolution","volume":"31","author":"Schirinzi","year":"2018","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib74","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.neuroscience.2013.11.062","article-title":"Dystonia as a network disorder: what is the role of the cerebellum?","volume":"260","author":"Prudente","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.neurot.2025.e00543_bib75","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1093\/brain\/awn168","article-title":"The basal ganglia and cerebellum interact in the expression of dystonic movement","volume":"131","author":"Neychev","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.neurot.2025.e00543_bib76","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1016\/S0140-6736(00)02410-7","article-title":"Treatment of DYT1-generalised dystonia by stimulation of the internal globus pallidus","volume":"355","author":"Coubes","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.neurot.2025.e00543_bib77","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1212\/01.wnl.0000267430.95106.ff","article-title":"Sixty hertz pallidal deep brain stimulation for primary torsion dystonia","volume":"69","author":"Alterman","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.neurot.2025.e00543_bib78","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/dyst.2023.11805","article-title":"Function and dysfunction of the dystonia network: an exploration of neural circuits that underlie the acquired and isolated dystonias","volume":"2","author":"Gill","year":"2023","journal-title":"Dystonia"},{"key":"10.1016\/j.neurot.2025.e00543_bib79","series-title":"Neurobiology of Disease Deep brain stimulation in animal models of dystonia.","volume":"vol. 175","author":"Richter","year":"2022"},{"key":"10.1016\/j.neurot.2025.e00543_bib80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.08352","article-title":"Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons","volume":"4","author":"Pappas","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.neurot.2025.e00543_bib81","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1038\/nn.3868","article-title":"Short latency cerebellar modulation of the basal ganglia","volume":"17","author":"Chen","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.neurot.2025.e00543_bib82","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1093\/brain\/awn168","article-title":"The basal ganglia and cerebellum interact in the expression of dystonic movement","volume":"131","author":"Neychev","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.neurot.2025.e00543_bib83","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fneur.2020.580540","article-title":"Reduced interhemispheric coherence in cerebellar kainic acid-induced lateralized dystonia","volume":"11","author":"Georgescu Margarint","year":"2020","journal-title":"Front Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib84","first-page":"716","article-title":"Tiagabine treatment in kainic acid induced cerebellar lesion of dystonia rat model","volume":"15","author":"Wang","year":"2016","journal-title":"EXCLI J"},{"key":"10.1016\/j.neurot.2025.e00543_bib85","first-page":"107","article-title":"Effects of early midline cerebellar lesion on cognitive and emotional functions in the rat","volume":"112","author":"Bobee","year":"2000"},{"key":"10.1016\/j.neurot.2025.e00543_bib86","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1212\/WNL.35.1.73","article-title":"Validity and reliability of a rating scale for the primary torsion dystonias","volume":"35","author":"Burke","year":"1985","journal-title":"Neurology"},{"key":"10.1016\/j.neurot.2025.e00543_bib87","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/08830738211059683","article-title":"Spasticity and dystonia are underidentified in young children at high risk for cerebral palsy","volume":"37","author":"Miao","year":"2022","journal-title":"J\u00a0Child Neurol"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00543_bib88","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/dmcn.15730","article-title":"Multiple motor disorders in cerebral palsy","volume":"66","author":"Dar","year":"2024","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib89","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.pediatrneurol.2019.11.007","article-title":"Characterizing posterior fossa syndrome: a survey of experts","volume":"104","author":"Wickenhauser","year":"2020","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib90","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/neuonc\/noab030","article-title":"Clinical features, neurologic recovery, and risk factors of postoperative posterior fossa syndrome and delayed recovery: a prospective study","volume":"23","author":"Khan","year":"2021","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.neurot.2025.e00543_bib91","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/dmcn.14295","article-title":"Deep brain stimulation for cerebral palsy: where are we now?","volume":"62","author":"Sanger","year":"2020","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.neurot.2025.e00543_bib92","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0165-0173(99)00040-5","article-title":"Basal ganglia and cerebellar loops: motor and cognitive circuits","volume":"31","author":"Middleton","year":"2000","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.neurot.2025.e00543_bib93","first-page":"S1878","article-title":"Cerebellar Deep Brain Stimulation in Cerebral Palsy: promising early results and a look forward to a larger clinical trial","author":"Cajigas","year":"2023","journal-title":"World Neurosurg"},{"key":"10.1016\/j.neurot.2025.e00543_bib94","first-page":"1","article-title":"Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study","volume":"7","author":"Schiff","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.neurot.2025.e00543_bib95","doi-asserted-by":"crossref","first-page":"114751","DOI":"10.1016\/j.expneurol.2024.114751","article-title":"The role of dorsolateral striatum in the effects of deep cerebellar stimulation-mediated motor recovery following ischemic stroke in rodents","volume":"376","author":"Chan","year":"2024","journal-title":"Exp Neurol"}],"container-title":["Neurotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747925000212?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747925000212?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:10:14Z","timestamp":1762560614000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878747925000212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":95,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1878747925000212"],"URL":"https:\/\/doi.org\/10.1016\/j.neurot.2025.e00543","relation":{},"ISSN":["1878-7479"],"issn-type":[{"value":"1878-7479","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thalamic deep brain stimulation improves movement in a cerebellar model of lesion-based status dystonicus","name":"articletitle","label":"Article Title"},{"value":"Neurotherapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurot.2025.e00543","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics.","name":"copyright","label":"Copyright"}],"article-number":"e00543"}}