{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T23:53:36Z","timestamp":1772927616565,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R03NS123833"],"award-info":[{"award-number":["R03NS123833"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS117598"],"award-info":[{"award-number":["R01NS117598"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["neurotherapeuticsjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotherapeutics"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.neurot.2025.e00829","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:24:55Z","timestamp":1767907495000},"page":"e00829","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraparenchymal B cell therapy protects neurological function and modulates local neuroinflammation in experimental hemorrhagic stroke"],"prefix":"10.1016","volume":"23","author":[{"given":"Saumya","family":"Maheshwari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liam J.","family":"Dwyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueyue","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James W.","family":"Aspden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark C.","family":"Poznansky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Whalen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruxandra F.","family":"S\u00eerbulescu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.neurot.2025.e00829_bib1","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1136\/jnnp-2013-306476","article-title":"Long-term prognosis after intracerebral haemorrhage: systematic review and meta-analysis","volume":"85","author":"Poon","year":"2014","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib2","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1186\/s12889-024-19923-7","article-title":"Global, regional, and national burden of intracerebral hemorrhage and its attributable risk factors from 1990 to 2021: results from the 2021 Global Burden of Disease Study","volume":"24","author":"Xu","year":"2024","journal-title":"BMC Public Health"},{"issue":"6","key":"10.1016\/j.neurot.2025.e00829_bib3","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1007\/s00415-006-0119-x","article-title":"Development and validation of a prognostic model to predict recovery following intracerebral hemorrhage","volume":"253","author":"Weimar","year":"2006","journal-title":"J Neurol"},{"key":"10.1016\/j.neurot.2025.e00829_bib4","doi-asserted-by":"crossref","DOI":"10.1177\/17562864211049208","article-title":"Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage","volume":"14","author":"Bautista","year":"2021","journal-title":"Ther Adv Neurol Disord"},{"issue":"14","key":"10.1016\/j.neurot.2025.e00829_bib5","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1056\/NEJMoa2308440","article-title":"Trial of early minimally invasive removal of intracerebral hemorrhage","volume":"390","author":"Pradilla","year":"2024","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5853\/jos.2019.02236","article-title":"Neuroinflammation after intracerebral hemorrhage and potential therapeutic targets","volume":"22","author":"Tschoe","year":"2020","journal-title":"J Stroke"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00829_bib7","first-page":"CD004583","article-title":"Corticosteroids for aneurysmal subarachnoid haemorrhage and primary intracerebral haemorrhage","author":"Feigin","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13643-025-02803-5","article-title":"Efficacy and safety of corticosteroids for stroke and traumatic brain injury: a systematic review and meta-analysis","volume":"14","author":"Wang","year":"2025","journal-title":"Syst Rev"},{"key":"10.1016\/j.neurot.2025.e00829_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2023.106077","article-title":"Inflammation and immunomodulation in central nervous system injury - b cells as a novel therapeutic opportunity","volume":"180","author":"Maheshwari","year":"2023","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neurot.2025.e00829_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coph.2015.04.006","article-title":"Regulatory plasma cells","volume":"23","author":"Fillatreau","year":"2015","journal-title":"Curr Opin Pharmacol"},{"issue":"10","key":"10.1016\/j.neurot.2025.e00829_bib11","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jcin.2009.08.010","article-title":"Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction","volume":"2","author":"Goodchild","year":"2009","journal-title":"JACC Cardiovasc Interv"},{"issue":"5","key":"10.1016\/j.neurot.2025.e00829_bib12","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/wrr.12584","article-title":"Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions","volume":"25","author":"S\u00eerbulescu","year":"2017","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.neurot.2025.e00829_bib13","article-title":"Protective and immunomodulatory functions of exogenous B cells in experimental hyperoxic lung injury","author":"Hanidziar","year":"2025","journal-title":"Anesth Analg"},{"issue":"13","key":"10.1016\/j.neurot.2025.e00829_bib14","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202302659R","article-title":"Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis","volume":"38","author":"S\u00eerbulescu","year":"2024","journal-title":"FASEB J"},{"issue":"17","key":"10.1016\/j.neurot.2025.e00829_bib15","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1089\/neu.2018.6368","article-title":"Intraparenchymal application of mature B lymphocytes improves structural and functional outcome after Contusion Traumatic Brain injury","volume":"36","author":"S\u00eerbulescu","year":"2019","journal-title":"J Neurotrauma"},{"issue":"12","key":"10.1016\/j.neurot.2025.e00829_bib16","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202101095RR","article-title":"B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype","volume":"35","author":"S\u00eerbulescu","year":"2021","journal-title":"FASEB J"},{"issue":"23","key":"10.1016\/j.neurot.2025.e00829_bib17","doi-asserted-by":"crossref","first-page":"8556","DOI":"10.1523\/JNEUROSCI.1623-11.2011","article-title":"Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke","volume":"31","author":"Ren","year":"2011","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s11011-013-9474-3","article-title":"Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice","volume":"29","author":"Bodhankar","year":"2014","journal-title":"Metab Brain Dis"},{"issue":"9","key":"10.1016\/j.neurot.2025.e00829_bib19","doi-asserted-by":"crossref","first-page":"4983","DOI":"10.1073\/pnas.1913292117","article-title":"B cells migrate into remote brain areas and support neurogenesis and functional recovery after focal stroke in mice","volume":"117","author":"Ortega","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1469-7580.2003.00203.x","article-title":"Neurotrophins and the immune system","volume":"203","author":"Vega","year":"2003","journal-title":"J Anat"},{"key":"10.1016\/j.neurot.2025.e00829_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2025.106819","article-title":"B cells upregulate NMDARs, respond to extracellular glutamate, and express mature BDNF to protect the brain from ischemic injury","volume":"207","author":"Torres","year":"2025","journal-title":"Neurobiol Dis"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib22","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s12974-023-02812-y","article-title":"B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells","volume":"20","author":"Dwyer","year":"2023","journal-title":"J Neuroinflammation"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib23","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/ilar.49.1.103","article-title":"Noninvasive bioluminescence imaging in small animals","volume":"49","author":"Zinn","year":"2008","journal-title":"ILAR J"},{"issue":"6","key":"10.1016\/j.neurot.2025.e00829_bib24","first-page":"24 1","article-title":"Detection of intracellular cytokines by flow cytometry","volume":"6","author":"Foster","year":"2007","journal-title":"Curr Protoc Im"},{"issue":"2","key":"10.1016\/j.neurot.2025.e00829_bib25","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/ana.24070","article-title":"NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage","volume":"75","author":"Ma","year":"2014","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1016\/j.neurot.2025.e00829_bib26","first-page":"261","article-title":"Traumatic subarachnoid hemorrhage: demographic and clinical study of 750 patients from the European brain injury consortium survey of head injuries","volume":"50","author":"Servadei","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.neurot.2025.e00829_bib27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-227X-9-15","article-title":"Intracranial bleeding in patients with traumatic brain injury: a prognostic study","volume":"9","author":"Perel","year":"2009","journal-title":"BMC Emerg Med"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00829_bib28","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nrneurol.2017.13","article-title":"The far-reaching scope of neuroinflammation after traumatic brain injury","volume":"13","author":"Simon","year":"2017","journal-title":"Nat Rev Neurol"},{"issue":"5","key":"10.1016\/j.neurot.2025.e00829_bib29","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000510040","article-title":"Dexamethasone in patients with spontaneous intracerebral hemorrhage: an updated meta-analysis","volume":"49","author":"Wintzer","year":"2020","journal-title":"Cerebrovasc Dis"},{"issue":"5 Neurocritical Care","key":"10.1016\/j.neurot.2025.e00829_bib30","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1212\/CON.0000000000000235","article-title":"Management of intracranial pressure","volume":"21","author":"Freeman","year":"2015","journal-title":"Continuum (Minneap Minn)"},{"key":"10.1016\/j.neurot.2025.e00829_bib31","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1186\/s12974-015-0409-2","article-title":"P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite","volume":"12","author":"Feng","year":"2015","journal-title":"J Neuroinflammation"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib32","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/STROKEAHA.117.018904","article-title":"Selective NLRP3 (pyrin domain-containing protein 3) inflammasome inhibitor reduces brain injury after intracerebral hemorrhage","volume":"49","author":"Ren","year":"2018","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/1673-5374.286951","article-title":"The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury","volume":"16","author":"Ismael","year":"2021","journal-title":"Neural Regen Res"},{"issue":"23","key":"10.1016\/j.neurot.2025.e00829_bib34","doi-asserted-by":"crossref","first-page":"eabq0712","DOI":"10.1126\/sciadv.abq0712","article-title":"CD4(+) T cells aggravate hemorrhagic brain injury","volume":"9","author":"Shi","year":"2023","journal-title":"Sci Adv"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib35","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s12035-024-04281-7","article-title":"Role of regulatory T cells in intracerebral hemorrhage","volume":"62","author":"Shang","year":"2025","journal-title":"Mol Neurobiol"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00829_bib36","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1177\/0271678X231214838","article-title":"CCL5 mediated astrocyte-T cell interaction disrupts blood-brain barrier in mice after hemorrhagic stroke","volume":"44","author":"Zhou","year":"2024","journal-title":"J Cerebr Blood Flow Metabol"},{"issue":"11","key":"10.1016\/j.neurot.2025.e00829_bib37","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1523\/JNEUROSCI.4070-13.2014","article-title":"CCR2+ Ly6C(hi) inflammatory monocyte recruitment exacerbates acute disability following intracerebral hemorrhage","volume":"34","author":"Hammond","year":"2014","journal-title":"J Neurosci"},{"key":"10.1016\/j.neurot.2025.e00829_bib38","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.intimp.2017.10.023","article-title":"Tim-3 enhances brain inflammation by promoting M1 macrophage polarization following intracerebral hemorrhage in mice","volume":"53","author":"Yu","year":"2017","journal-title":"Int Immunopharmacol"},{"issue":"589","key":"10.1016\/j.neurot.2025.e00829_bib39","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abc7029","article-title":"Brain injury instructs bone marrow cellular lineage destination to reduce neuroinflammation","volume":"13","author":"Shi","year":"2021","journal-title":"Sci Transl Med"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00829_bib40","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.celrep.2013.10.010","article-title":"Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta","volume":"5","author":"Michaud","year":"2013","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib41","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1172\/JCI88647","article-title":"TGF-beta1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage","volume":"127","author":"Taylor","year":"2017","journal-title":"J Clin Investig"},{"key":"10.1016\/j.neurot.2025.e00829_bib42","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bbrc.2023.03.007","article-title":"TGF-beta1 ameliorates BBB injury and improves long-term outcomes in mice after ICH","volume":"654","author":"Wen","year":"2023","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib43","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2021.12138","article-title":"Transforming growth factor-beta1 functions as a competitive endogenous RNA that ameliorates intracranial hemorrhage injury by sponging microRNA-93-5p","volume":"24","author":"Wang","year":"2021","journal-title":"Mol Med Rep"},{"issue":"14","key":"10.1016\/j.neurot.2025.e00829_bib44","doi-asserted-by":"crossref","first-page":"776","DOI":"10.21037\/atm-22-2770","article-title":"Interleukin-35 attenuates blood-brain barrier dysfunction caused by cerebral ischemia-reperfusion injury through inhibiting brain endothelial cell injury","volume":"10","author":"Qian","year":"2022","journal-title":"Ann Transl Med"},{"issue":"5","key":"10.1016\/j.neurot.2025.e00829_bib45","doi-asserted-by":"crossref","first-page":"651","DOI":"10.21037\/tp-22-100","article-title":"Interleukin-35 exhibits protective effects in a rat model of hypoxic-ischemic encephalopathy through the inhibition of microglia-mediated inflammation","volume":"11","author":"Liu","year":"2022","journal-title":"Transl Pediatr"},{"key":"10.1016\/j.neurot.2025.e00829_bib46","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.nbd.2017.03.016","article-title":"Alternative activation-skewed microglia\/macrophages promote hematoma resolution in experimental intracerebral hemorrhage","volume":"103","author":"Chang","year":"2017","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.neurot.2025.e00829_bib47","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.bbi.2021.02.001","article-title":"Microglia-derived interleukin-10 accelerates post-intracerebral hemorrhage hematoma clearance by regulating CD36","volume":"94","author":"Li","year":"2021","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.neurot.2025.e00829_bib48","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.brainresbull.2019.05.016","article-title":"Interleukin-33 reduces neuronal damage and white matter injury via selective microglia M2 polarization after intracerebral hemorrhage in rats","volume":"150","author":"Chen","year":"2019","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.neurot.2025.e00829_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2025.110336","article-title":"IL-33 exerts neuroprotective effects through activation of ST2\/AKT signaling axis in microglia after subarachnoid hemorrhage in rats","volume":"269","author":"Chen","year":"2025","journal-title":"Neuropharmacology"},{"issue":"5","key":"10.1016\/j.neurot.2025.e00829_bib50","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.1007\/s12035-016-9947-6","article-title":"IL-33 exerts neuroprotective effect in mice intracerebral hemorrhage model through suppressing inflammation\/apoptotic\/autophagic pathway","volume":"54","author":"Gao","year":"2017","journal-title":"Mol Neurobiol"},{"issue":"12","key":"10.1016\/j.neurot.2025.e00829_bib51","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20200213","article-title":"Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage","volume":"217","author":"Li","year":"2020","journal-title":"J Exp Med"},{"issue":"12","key":"10.1016\/j.neurot.2025.e00829_bib52","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.08.012","article-title":"The volume of the spleen and its correlates after acute stroke","volume":"25","author":"Chiu","year":"2016","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"5","key":"10.1016\/j.neurot.2025.e00829_bib53","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/sj.jcbfm.9600217","article-title":"Experimental stroke induces massive, rapid activation of the peripheral immune system","volume":"26","author":"Offner","year":"2006","journal-title":"J Cerebr Blood Flow Metabol"},{"issue":"4","key":"10.1016\/j.neurot.2025.e00829_bib54","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s11481-012-9406-8","article-title":"A transient decrease in spleen size following stroke corresponds to splenocyte release into systemic circulation","volume":"7","author":"Seifert","year":"2012","journal-title":"J Neuroimmune Pharmacol"},{"issue":"11","key":"10.1016\/j.neurot.2025.e00829_bib55","doi-asserted-by":"crossref","first-page":"6523","DOI":"10.4049\/jimmunol.176.11.6523","article-title":"Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages","volume":"176","author":"Offner","year":"2006","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.neurot.2025.e00829_bib56","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1161\/01.STR.0000258346.68966.9d","article-title":"Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression","volume":"38","author":"Chamorro","year":"2007","journal-title":"Stroke"},{"issue":"7","key":"10.1016\/j.neurot.2025.e00829_bib57","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nrneurol.2012.98","article-title":"The immunology of acute stroke","volume":"8","author":"Chamorro","year":"2012","journal-title":"Nat Rev Neurol"},{"issue":"6","key":"10.1016\/j.neurot.2025.e00829_bib58","first-page":"753","article-title":"Sex-based differences in the outcomes of intracerebral haemorrhage: a systematic review and meta-analysis","volume":"53","author":"Yang","year":"2024","journal-title":"Cerebrovasc Dis"},{"issue":"4","key":"10.1016\/j.neurot.2025.e00829_bib59","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1517\/14712598.2011.554811","article-title":"Donor lymphocyte infusion following allogeneic hematopoietic stem cell transplantation","volume":"11","author":"Roddie","year":"2011","journal-title":"Expet Opin Biol Ther"},{"issue":"1","key":"10.1016\/j.neurot.2025.e00829_bib60","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s12967-017-1330-5","article-title":"GMP-production of purified human B lymphocytes for the adoptive transfer in patients after allogeneic hematopoietic stem cell transplantation","volume":"15","author":"Tittlbach","year":"2017","journal-title":"J Transl Med"}],"container-title":["Neurotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747925003071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878747925003071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T04:05:16Z","timestamp":1772856316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878747925003071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1878747925003071"],"URL":"https:\/\/doi.org\/10.1016\/j.neurot.2025.e00829","relation":{},"ISSN":["1878-7479"],"issn-type":[{"value":"1878-7479","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intraparenchymal B cell therapy protects neurological function and modulates local neuroinflammation in experimental hemorrhagic stroke","name":"articletitle","label":"Article Title"},{"value":"Neurotherapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neurot.2025.e00829","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics.","name":"copyright","label":"Copyright"}],"article-number":"e00829"}}