{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:29:34Z","timestamp":1783920574033,"version":"3.55.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T00:00:00Z","timestamp":1375833600000},"content-version":"vor","delay-in-days":218,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"funder":[{"name":"Pain Relief Foundation, Liverpool, UK"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1016\/j.nicl.2013.07.011","type":"journal-article","created":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T17:59:58Z","timestamp":1376071198000},"page":"163-170","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Structural alterations in brainstem of fibromyalgia syndrome patients correlate with sensitivity to mechanical pressure"],"prefix":"10.1016","volume":"3","author":[{"given":"Nicholas","family":"Fallon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamaan","family":"Alghamdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Sluming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Turo","family":"Nurmikko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrej","family":"Stancak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nicl.2013.07.011_bb0125","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.rdc.2009.06.006","article-title":"From fibrositis to functional somatic syndromes to a bell-shaped curve of pain and sensory sensitivity: evolution of a clinical construct","volume":"35","author":"Ablin","year":"2009","journal-title":"Rheumatic Diseases Clinics of North America"},{"key":"10.1016\/j.nicl.2013.07.011_bb0165","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.neuroimage.2009.05.029","article-title":"An evaluation of four automatic methods of segmenting the subcortical structures in the brain","volume":"47","author":"Babalola","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0310","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1523\/JNEUROSCI.4123-07.2008","article-title":"Beyond feeling: chronic pain hurts the brain, disrupting the default-mode network dynamics","volume":"28","author":"Baliki","year":"2008","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nicl.2013.07.011_bb0280","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1002\/nbm.1692","article-title":"A brain MRI study of chronic fatigue syndrome: evidence of brainstem dysfunction and altered homeostasis","volume":"24","author":"Barnden","year":"2011","journal-title":"NMR in Biomedicine"},{"key":"10.1016\/j.nicl.2013.07.011_bb0150","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.nicl.2013.07.011_bb0170","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate \u2014 a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"Journal of the Royal Statistical Society: Series B Methodological"},{"key":"10.1016\/j.nicl.2013.07.011_bb0005","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1471-2474-8-27","article-title":"An internet survey of 2,596 people with fibromyalgia","volume":"8","author":"Bennett","year":"2007","journal-title":"BMC Musculoskeletal Disorders"},{"key":"10.1016\/j.nicl.2013.07.011_bb0195","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1526-4637.2008.00412.x","article-title":"Chronic pain is associated with brain volume loss in older adults: preliminary evidence","volume":"9","author":"Buckalew","year":"2008","journal-title":"Pain Medicine"},{"key":"10.1016\/j.nicl.2013.07.011_bb0155","first-page":"728","article-title":"The fibromyalgia impact questionnaire: development and validation","volume":"18","author":"Burckhardt","year":"1991","journal-title":"Journal of Rheumatology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0040","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/PSY.0b013e3181a32da0","article-title":"Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia","volume":"71","author":"Burgmer","year":"2009","journal-title":"Psychosomatic Medicine"},{"key":"10.1016\/j.nicl.2013.07.011_bb0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.pscychresns.2005.09.006","article-title":"Gray matter density reduction in the insula in fire survivors with posttraumatic stress disorder: a voxel-based morphometric study","volume":"146","author":"Chen","year":"2006","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0015","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.amjmed.2009.09.006","article-title":"Fibromyalgia: an overview","volume":"122","author":"Clauw","year":"2009","journal-title":"American Journal of Medicine"},{"key":"10.1016\/j.nicl.2013.07.011_bb0030","doi-asserted-by":"crossref","first-page":"907","DOI":"10.4065\/mcp.2011.0206","article-title":"The science of fibromyalgia","volume":"86","author":"Clauw","year":"2011","journal-title":"Mayo Clinic Proceedings"},{"key":"10.1016\/j.nicl.2013.07.011_bb0290","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1093\/gerona\/61.11.1166","article-title":"Aerobic exercise training increases brain volume in aging humans","volume":"61","author":"Colcombe","year":"2006","journal-title":"The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences"},{"key":"10.1016\/j.nicl.2013.07.011_bb0105","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.neuroimage.2005.02.037","article-title":"Gray matter volume reduction in the chronic fatigue syndrome","volume":"26","author":"de Lange","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0295","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1002\/hipo.20547","article-title":"Aerobic fitness is associated with hippocampal volume in elderly humans","volume":"19","author":"Erickson","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.nicl.2013.07.011_bb0275","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.pain.2006.09.001","article-title":"Anticipatory brainstem activity predicts neural processing of pain in humans","volume":"128","author":"Fairhurst","year":"2007","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0335","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.clinph.2012.06.014","article-title":"Ipsilateral cortical activation in fibromyalgia patients during brushing correlates with symptom severity","volume":"124","author":"Fallon","year":"2013","journal-title":"Clinical Neurophysiology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0205","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1136\/jnnp.73.2.191","article-title":"Cognitive dysfunction after isolated brain stem insult. An underdiagnosed cause of long term morbidity","volume":"73","author":"Garrard","year":"2002","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.nicl.2013.07.011_bb0260","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3174\/ajnr.A1909","article-title":"Tactile sensory and pain networks in the human spinal cord and brain stem mapped by means of functional MR imaging","volume":"31","author":"Ghazni","year":"2010","journal-title":"AJNR. American Journal of Neuroradiology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0145","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.pscychresns.2011.09.014","article-title":"Age effect on subcortical structures in healthy adults","volume":"203","author":"Goodro","year":"2012","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0330","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/art.10225","article-title":"Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia","volume":"46","author":"Gracely","year":"2002","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0220","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/nrrheum.2010.107","article-title":"Assessment of mechanisms in localized and widespread musculoskeletal pain","volume":"6","author":"Graven-Nielsen","year":"2010","journal-title":"Nature Reviews. Rheumatology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0305","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1073\/pnas.0135058100","article-title":"Functional connectivity in the resting brain: a network analysis of the default mode hypothesis","volume":"100","author":"Greicius","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.nicl.2013.07.011_bb0350","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1002\/art.27585","article-title":"Thalamic atrophy associated with painful osteoarthritis of the hip is reversible after arthroplasty: a longitudinal voxel-based morphometric study","volume":"62","author":"Gwilym","year":"2010","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0185","doi-asserted-by":"crossref","first-page":"E507","DOI":"10.1227\/NEU.0b013e3182214cea","article-title":"\u201cIs Chiari-I malformation associated with fibromyalgia?\u201d revisited","volume":"69","author":"Heffez","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.nicl.2013.07.011_bb0210","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1155\/2008\/635187","article-title":"Etiology of frontal network syndromes in isolated subtentorial stroke","volume":"20","author":"Hoffmann","year":"2008","journal-title":"Behavioural Neurology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0070","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.pain.2009.03.017","article-title":"No consistent difference in gray matter volume between individuals with fibromyalgia and age-matched healthy subjects when controlling for affective disorder","volume":"143","author":"Hsu","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0245","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.pain.2009.03.018","article-title":"Evidence of dysfunctional pain inhibition in fibromyalgia reflected in rACC during provoked pain","volume":"144","author":"Jensen","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0250","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1744-8069-8-32","article-title":"Patients with fibromyalgia display less functional connectivity in the brain's pain inhibitory network","volume":"8","author":"Jensen","year":"2012","journal-title":"Molecular Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0080","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.neuroimage.2005.02.013","article-title":"The effect of filter size on VBM analyses of DT-MRI data","volume":"26","author":"Jones","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0020","doi-asserted-by":"crossref","first-page":"R127","DOI":"10.1186\/ar3432","article-title":"Postural control deficits in people with fibromyalgia: a pilot study","volume":"13","author":"Jones","year":"2011","journal-title":"Arthritis Research & Therapy"},{"key":"10.1016\/j.nicl.2013.07.011_bb0235","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.pain.2004.12.032","article-title":"Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition","volume":"114","author":"Julien","year":"2005","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0240","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3959(96)03295-2","article-title":"Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation (HNCS) in fibromyalgia patients and healthy subjects","volume":"70","author":"Kosek","year":"1997","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0055","doi-asserted-by":"crossref","first-page":"4004","DOI":"10.1523\/JNEUROSCI.0098-07.2007","article-title":"Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?","volume":"27","author":"Kuchinad","year":"2007","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nicl.2013.07.011_bb0325","doi-asserted-by":"crossref","first-page":"11642","DOI":"10.1523\/JNEUROSCI.2638-08.2008","article-title":"Identifying brain activity specifically related to the maintenance and perceptual consequence of central sensitization in humans","volume":"28","author":"Lee","year":"2008","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nicl.2013.07.011_bb0230","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/j.neubiorev.2008.01.003","article-title":"Pro-nociceptive action of cholecystokinin in the periaqueductal grey: a role in neuropathic and anxiety-induced hyperalgesic states","volume":"32","author":"Lovick","year":"2008","journal-title":"Neuroscience and Biobehavioral Reviews"},{"key":"10.1016\/j.nicl.2013.07.011_bb0060","doi-asserted-by":"crossref","first-page":"3222","DOI":"10.1093\/brain\/awn229","article-title":"Working memory performance is correlated with local brain morphology in the medial frontal and anterior cingulate cortex in fibromyalgia patients: structural correlates of pain\u2013cognition interaction","volume":"131","author":"Luerding","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0035","doi-asserted-by":"crossref","first-page":"3960","DOI":"10.1002\/art.24070","article-title":"White and gray matter abnormalities in the brain of patients with fibromyalgia: a diffusion-tensor and volumetric imaging study","volume":"58","author":"Lutz","year":"2008","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0255","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00482-009-0842-1","article-title":"Chronic pain alters the structure of the brain","volume":"23","author":"May","year":"2009","journal-title":"Schmerz"},{"key":"10.1016\/j.nicl.2013.07.011_bb0090","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1177\/1073858410396220","article-title":"Structural brain imaging: a window into chronic pain","volume":"17","author":"May","year":"2011","journal-title":"The Neuroscientist"},{"key":"10.1016\/j.nicl.2013.07.011_bb0285","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/acr.20118","article-title":"Association between physical exercise, body mass index, and risk of fibromyalgia: longitudinal data from the Norwegian Nord-Trondelag Health Study","volume":"62","author":"Mork","year":"2010","journal-title":"Arthritis Care and Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0200","series-title":"Duvernoy's Atlas of the Human Brain Stem and Cerebellum","author":"Naidich","year":"2009"},{"key":"10.1016\/j.nicl.2013.07.011_bb0315","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1002\/art.27497","article-title":"Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity","volume":"62","author":"Napadow","year":"2010","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0365","doi-asserted-by":"crossref","DOI":"10.1002\/art.34412","article-title":"Decreased intrinsic brain connectivity is associated with reduced clinical pain in fibromyalgia","author":"Napadow","year":"2012","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0085","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroimage.2011.02.046","article-title":"A Bayesian model of shape and appearance for subcortical brain segmentation","volume":"56","author":"Patenaude","year":"2011","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0225","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/jnr.22512","article-title":"Central amplification and fibromyalgia: disorder of pain processing","volume":"89","author":"Petersel","year":"2011","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0130","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.berh.2011.02.005","article-title":"Central pain mechanisms in chronic pain states\u2014maybe it is all in their head","volume":"25","author":"Phillips","year":"2011","journal-title":"Best Practice & Research. Clinical Rheumatology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0215","doi-asserted-by":"crossref","first-page":"E8","DOI":"10.3171\/foc.2006.21.6.10","article-title":"Deep brain stimulation for the treatment of various chronic pain syndromes","volume":"21","author":"Rasche","year":"2006","journal-title":"Neurosurgical Focus"},{"key":"10.1016\/j.nicl.2013.07.011_bb0065","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jpain.2010.10.003","article-title":"Gray matter volumes of pain-related brain areas are decreased in fibromyalgia syndrome","volume":"12","author":"Robinson","year":"2011","journal-title":"The Journal of Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0135","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/j.1530-0277.2011.01440.x","article-title":"Subcortical volumes in long-term abstinent alcoholics: associations with psychiatric comorbidity","volume":"35","author":"Sameti","year":"2011","journal-title":"Alcoholism, Clinical and Experimental Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0100","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1212\/01.wnl.0000183067.94400.80","article-title":"Gray matter decrease in patients with chronic tension type headache","volume":"65","author":"Schmidt-Wilcke","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0190","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.pain.2006.05.004","article-title":"Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients","volume":"125","author":"Schmidt-Wilcke","year":"2006","journal-title":"Pain"},{"issue":"Suppl. 1","key":"10.1016\/j.nicl.2013.07.011_bb0050","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1016\/j.pain.2007.05.010","article-title":"Striatal grey matter increase in patients suffering from fibromyalgia\u2014a voxel-based morphometry study","volume":"132","author":"Schmidt-Wilcke","year":"2007","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0095","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1053\/j.gastro.2010.03.049","article-title":"Regional gray matter density changes in brains of patients with irritable bowel syndrome","volume":"139","author":"Seminowicz","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0160","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23","author":"Smith","year":"2004","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0075","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","article-title":"Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data","volume":"31","author":"Smith","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0360","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1002\/ar.21383","article-title":"Improved assessment of ex vivo brainstem neuroanatomy with high-resolution MRI and DTI at 7Tesla","volume":"294","author":"Soria","year":"2011","journal-title":"Anatomical Record (Hoboken, N.J.: 2007)"},{"key":"10.1016\/j.nicl.2013.07.011_bb0265","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s11926-011-0206-6","article-title":"Evidence for shared pain mechanisms in osteoarthritis, low back pain, and fibromyalgia","volume":"13","author":"Staud","year":"2011","journal-title":"Current Rheumatology Reports"},{"key":"10.1016\/j.nicl.2013.07.011_bb0345","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.berh.2010.01.010","article-title":"Peripheral pain mechanisms in chronic widespread pain","volume":"25","author":"Staud","year":"2011","journal-title":"Best Practice & Research. Clinical Rheumatology"},{"key":"10.1016\/j.nicl.2013.07.011_bb0355","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.neuroimage.2008.05.044","article-title":"Changes in brain gray matter due to repetitive painful stimulation","volume":"42","author":"Teutsch","year":"2008","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0175","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00002508-200205000-00006","article-title":"Functional abnormalities of the cervical cord and lower medulla and their effect on pain: observations in chronic pain patients with incidental mild Chiari I malformation and moderate to severe cervical cord compression","volume":"18","author":"Thimineur","year":"2002","journal-title":"The Clinical Journal of Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0045","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/PSY.0b013e31818d1e02","article-title":"Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study","volume":"71","author":"Valet","year":"2009","journal-title":"Psychosomatic Medicine"},{"key":"10.1016\/j.nicl.2013.07.011_bb0110","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0006-3223(02)01359-8","article-title":"Reduced hippocampal volume and total white matter volume in posttraumatic stress disorder","volume":"52","author":"Villarreal","year":"2002","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.nicl.2013.07.011_bb0180","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1227\/NEU.0b013e3182039a31","article-title":"Is Chiari I malformation associated with fibromyalgia?","volume":"68","author":"Watson","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.nicl.2013.07.011_bb0120","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.jpain.2009.06.001","article-title":"Understanding fibromyalgia: lessons from the broader pain research community","volume":"10","author":"Williams","year":"2009","journal-title":"The Journal of Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0010","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/art.1780330203","article-title":"The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee","volume":"33","author":"Wolfe","year":"1990","journal-title":"Arthritis and Rheumatism"},{"key":"10.1016\/j.nicl.2013.07.011_bb0025","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1002\/acr.20140","article-title":"The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity","volume":"62","author":"Wolfe","year":"2010","journal-title":"Arthritis Care and Research"},{"key":"10.1016\/j.nicl.2013.07.011_bb0340","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.pain.2010.09.030","article-title":"Central sensitization: implications for the diagnosis and treatment of pain","volume":"152","author":"Woolf","year":"2011","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0270","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.pain.2005.01.005","article-title":"A role for the brainstem in central sensitisation in humans. Evidence from functional magnetic resonance imaging","volume":"114","author":"Zambreanu","year":"2005","journal-title":"Pain"},{"key":"10.1016\/j.nicl.2013.07.011_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroimage.2009.09.001","article-title":"Combining shape and connectivity analysis: an MRI study of thalamic degeneration in Alzheimer's disease","volume":"49","author":"Zarei","year":"2010","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2013.07.011_bb0300","doi-asserted-by":"crossref","DOI":"10.1186\/1744-8069-6-80","article-title":"Imaging the functional connectivity of the periaqueductal gray during genuine and sham electroacupuncture treatment","volume":"6","author":"Zyloney","year":"2010","journal-title":"Molecular Pain"}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158213000983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158213000983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T03:56:45Z","timestamp":1761969405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158213000983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":72,"alternative-id":["S2213158213000983"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2013.07.011","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural alterations in brainstem of fibromyalgia syndrome patients correlate with sensitivity to mechanical pressure","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2013.07.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}