{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:29:57Z","timestamp":1791322197069,"version":"4.3.1"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T00:00:00Z","timestamp":1489104000000},"content-version":"vor","delay-in-days":68,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1016\/j.nicl.2017.03.004","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T19:49:31Z","timestamp":1489693771000},"page":"685-691","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"special_numbering":"C","title":["Subtle hippocampal deformities in breast cancer survivors with reduced episodic memory and self-reported cognitive concerns"],"prefix":"10.1016","volume":"14","author":[{"given":"Alexandra C.","family":"Apple","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Ryals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn I.","family":"Alpert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne I.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-An","family":"Shih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Dokucu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.","family":"Penedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel L.","family":"Voss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0005","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1158\/0008-5472.CAN-14-2237","article-title":"Stem cell transplantation reverses chemotherapy-induced cognitive dysfunction","volume":"75","author":"Acharya","year":"2015","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1214\/aop\/1176996176","article-title":"Level-crossings for random fields","volume":"4","author":"Adler","year":"1976","journal-title":"Ann. Probab."},{"key":"10.1016\/j.nicl.2017.03.004_bb0015","series-title":"Classics in Applied Mathematics 62 (SIAM ed., pp. 1 Electronic Text (xxii, 280 p))","article-title":"The geometry of random fields","author":"Adler","year":"2010"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0020","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/mono.12033","article-title":"III. NIH toolbox cognition battery (CB): measuring episodic memory","volume":"78","author":"Bauer","year":"2013","journal-title":"Monogr. Soc. Res. Child Dev."},{"issue":"2","key":"10.1016\/j.nicl.2017.03.004_bb0025","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1023\/B:VISI.0000043755.93987.aa","article-title":"Computing large deformation metric mappings via geodesic flows of diffeomorphisms","volume":"61","author":"Beg","year":"2005","journal-title":"Int. J. Comput. Vis."},{"issue":"10","key":"10.1016\/j.nicl.2017.03.004_bb0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0025349","article-title":"Breast cancer affects both the hippocampus volume and the episodic autobiographical memory retrieval","volume":"6","author":"Bergouignan","year":"2011","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0035","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0896-6273(02)00830-9","article-title":"The human hippocampus and spatial and episodic memory","volume":"35","author":"Burgess","year":"2002","journal-title":"Neuron"},{"issue":"23","key":"10.1016\/j.nicl.2017.03.004_bb0040","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1212\/WNL.0b013e318258f744","article-title":"Neuro-QOL: brief measures of health-related quality of life for clinical research in neurology","volume":"78","author":"Cella","year":"2012","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.nicl.2017.03.004_bb0045","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1158\/1078-0432.CCR-11-2000","article-title":"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy","volume":"18","author":"Christie","year":"2012","journal-title":"Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb0050","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neuroimage.2008.05.021","article-title":"False discovery rate revisited: FDR and topological inference using Gaussian random fields","volume":"44","author":"Chumbley","year":"2009","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb0055","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.neuroimage.2011.01.050","article-title":"Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment","volume":"56","author":"Costafreda","year":"2011","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.03.004_bb2000","doi-asserted-by":"crossref","first-page":"11406","DOI":"10.1073\/pnas.95.19.11406","article-title":"Hippocampal morphometry in schizophrenia by high dimensional brain mapping","volume":"95","author":"Csernansky","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"Suppl. 1","key":"10.1016\/j.nicl.2017.03.004_bb0060","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1016\/j.neuroimage.2004.07.025","article-title":"Computational anatomy and neuropsychiatric disease: probabilistic assessment of variation and statistical inference of group difference, hemispheric asymmetry, and time-dependent change","volume":"23","author":"Csernansky","year":"2004","journal-title":"NeuroImage"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0065","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.neuroimage.2004.12.036","article-title":"Preclinical detection of Alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly","volume":"25","author":"Csernansky","year":"2005","journal-title":"NeuroImage"},{"issue":"7","key":"10.1016\/j.nicl.2017.03.004_bb0070","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/jbiol50","article-title":"CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo","volume":"5","author":"Dietrich","year":"2006","journal-title":"J. Biol."},{"issue":"12","key":"10.1016\/j.nicl.2017.03.004_bb0075","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1634\/theoncologist.2008-0130","article-title":"Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy","volume":"13","author":"Dietrich","year":"2008","journal-title":"Oncologist"},{"key":"10.1016\/j.nicl.2017.03.004_bb0080","series-title":"The Human Hippocampus : An Atlas of Applied Anatomy","author":"Duvernoy","year":"1988"},{"issue":"9814","key":"10.1016\/j.nicl.2017.03.004_bb0085","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0140-6736(11)61625-5","article-title":"Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials","volume":"379","author":"Peto","year":"2012","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.nicl.2017.03.004_bb0090","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1002\/cncr.28509","article-title":"Annual report to the nation on the status of cancer, 1975\u20132010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer","volume":"120","author":"Edwards","year":"2014","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0095","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","article-title":"Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain","volume":"33","author":"Fischl","year":"2002","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0100","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1006\/nimg.2001.1037","article-title":"Thresholding of statistical maps in functional neuroimaging using the false discovery rate","volume":"15","author":"Genovese","year":"2002","journal-title":"NeuroImage"},{"issue":"7","key":"10.1016\/j.nicl.2017.03.004_bb0105","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.ctrv.2012.05.002","article-title":"Objective and subjective cognitive impairment following chemotherapy for cancer: a systematic review","volume":"38","author":"Hutchinson","year":"2012","journal-title":"Cancer Treat. Rev."},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb0110","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/cncr.22368","article-title":"Smaller regional volumes of brain gray and white matter demonstrated in breast cancer survivors exposed to adjuvant chemotherapy","volume":"109","author":"Inagaki","year":"2007","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0115","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1053\/j.seminoncol.2011.03.014","article-title":"An update on cancer- and chemotherapy-related cognitive dysfunction: current status","volume":"38","author":"Janelsins","year":"2011","journal-title":"Semin. Oncol."},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb0120","doi-asserted-by":"crossref","first-page":"102","DOI":"10.3109\/09540261.2013.864260","article-title":"Prevalence, mechanisms, and management of cancer-related cognitive impairment","volume":"26","author":"Janelsins","year":"2014","journal-title":"Int. Rev. Psychiatry"},{"key":"10.1016\/j.nicl.2017.03.004_bb2500","article-title":"On the geometry and shape of brain submanifolds: processing of MR images of the human brain","author":"Joshi","year":"1997","journal-title":"Inter J Pattern Recognition Artificial Intelligence"},{"key":"10.1016\/j.nicl.2017.03.004_bb0125","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.cortex.2014.01.010","article-title":"Neural correlates of chemotherapy-related cognitive impairment","volume":"54","author":"Kaiser","year":"2014","journal-title":"Cortex"},{"issue":"21","key":"10.1016\/j.nicl.2017.03.004_bb0130","doi-asserted-by":"crossref","first-page":"6665","DOI":"10.1158\/1078-0432.CCR-09-1227","article-title":"Regional brain activation during verbal declarative memory in metastatic breast cancer. [Research support, N.I.H., extramural research support, non-U.S. gov't]","volume":"15","author":"Kesler","year":"2009","journal-title":"Clin. Cancer Res."},{"issue":"Suppl","key":"10.1016\/j.nicl.2017.03.004_bb0135","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1016\/j.bbi.2012.05.017","article-title":"Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors","volume":"30","author":"Kesler","year":"2013","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0140","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.neuroimage.2008.03.024","article-title":"FreeSurfer-initiated fully-automated subcortical brain segmentation in MRI using large deformation diffeomorphic metric mapping","volume":"41","author":"Khan","year":"2008","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.03.004_bb0145","first-page":"444","article-title":"A prospective study of grey matter and cognitive function alterations in chemotherapy-treated breast cancer patients","volume":"3","author":"Lepage","year":"2014","journal-title":"Spring"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0150","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s11682-012-9213-0","article-title":"Differences in verbal memory retrieval in breast cancer chemotherapy patients compared to healthy controls: a prospective fMRI study","volume":"7","author":"Lopez Zunini","year":"2013","journal-title":"Brain Imaging Behav."},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0155","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/s10549-010-1088-4","article-title":"Gray matter reduction associated with systemic chemotherapy for breast cancer: a prospective MRI study","volume":"123","author":"McDonald","year":"2010","journal-title":"Breast Cancer Res. Treat."},{"issue":"7","key":"10.1016\/j.nicl.2017.03.004_bb0160","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/ncponc0228","article-title":"Adjuvant chemotherapy for stage II colorectal cancer: the time is right! [Historical ArticleReview]","volume":"2","author":"Midgley","year":"2005","journal-title":"Nat. Clin. Pract. Oncol."},{"key":"10.1016\/j.nicl.2017.03.004_bb1000","doi-asserted-by":"crossref","first-page":"15172","DOI":"10.1073\/pnas.2136624100","article-title":"Labeled cortical mantle distance maps of the cingulate quantify differences between dementia of the Alzheimer type and healthy aging","volume":"100","author":"Miller","year":"2003","journal-title":"Proceedings National Academy Science USA"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0165","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1017\/S1478951507000442","article-title":"Chemotherapy and cognitive deficits: mechanisms, findings, and potential interventions","volume":"5","author":"Nelson","year":"2007","journal-title":"Palliat. Support. Care"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0170","first-page":"237","article-title":"Effects of tamoxifen on morphological and ultrastructural aspects of developing hippocampus of rat","volume":"13","author":"Nobakht","year":"2009","journal-title":"Iran. Biomed. J."},{"issue":"6","key":"10.1016\/j.nicl.2017.03.004_bb0175","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity and response criteria of the eastern cooperative oncology group","volume":"5","author":"Oken","year":"1982","journal-title":"Am. J. Clin. Oncol."},{"issue":"7139","key":"10.1016\/j.nicl.2017.03.004_bb0180","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1136\/bmj.316.7139.1236","article-title":"What's wrong with Bonferroni adjustments","volume":"316","author":"Perneger","year":"1998","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.nicl.2017.03.004_bb0185","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/hipo.20173","article-title":"Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons","volume":"16","author":"Prange-Kiel","year":"2006","journal-title":"Hippocampus"},{"issue":"8","key":"10.1016\/j.nicl.2017.03.004_bb0190","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/hbm.21102","article-title":"Cerebral hyporesponsiveness and cognitive impairment 10 years after chemotherapy for breast cancer","volume":"32","author":"de Ruiter","year":"2011","journal-title":"Hum. Brain Mapp."},{"issue":"12","key":"10.1016\/j.nicl.2017.03.004_bb0195","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1002\/hbm.21422","article-title":"Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging","volume":"33","author":"de Ruiter","year":"2012","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2017.03.004_bb0200","series-title":"Hippocampal Memory Impairment in Breast Cancer Survivors after Chemotherapy Measurement Using Covert Testing","author":"Ryals","year":"2015"},{"issue":"2","key":"10.1016\/j.nicl.2017.03.004_bb0205","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.bbr.2007.08.004","article-title":"Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat","volume":"186","author":"Seigers","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.nicl.2017.03.004_bb0210","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.bbr.2009.10.009","article-title":"Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release","volume":"207","author":"Seigers","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.nicl.2017.03.004_bb0215","series-title":"NIH Toolbox, Technical Manual","author":"Slotkin","year":"2012"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0220","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.media.2004.06.004","article-title":"Boundary and medial shape analysis of the hippocampus in schizophrenia","volume":"8","author":"Styner","year":"2004","journal-title":"Med. Image Anal."},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0225","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/annonc\/mdm500","article-title":"Cancer and cancer-therapy related cognitive dysfunction: an international perspective from the Venice cognitive workshop","volume":"19","author":"Vardy","year":"2008","journal-title":"Ann. Oncol."},{"issue":"5","key":"10.1016\/j.nicl.2017.03.004_bb0230","doi-asserted-by":"crossref","first-page":"503","DOI":"10.2217\/WHE.09.36","article-title":"Breast cancer treatment and cognitive function: the current state of evidence, underlying mechanisms and potential treatments","volume":"5","author":"Vodermaier","year":"2009","journal-title":"Women's Health (Lond. Engl.)"},{"issue":"2","key":"10.1016\/j.nicl.2017.03.004_bb0235","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S1053-8119(03)00361-6","article-title":"Changes in hippocampal volume and shape across time distinguish dementia of the Alzheimer type from healthy aging","volume":"20","author":"Wang","year":"2003","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.nicl.2017.03.004_bb1500","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.neuroimage.2005.09.017","article-title":"Abnormalities of hippocampal surface structure in very mild dementia of the Alzheimer type","volume":"30","author":"Wang","year":"2006","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb1600","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1109\/TMI.2006.887380","article-title":"Large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the Alzheimer type.","volume":"26","author":"Wang","year":"2007","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.nicl.2017.03.004_bb0240","article-title":"Reduced prefrontal activation during working and long-term memory tasks and impaired patient-reported cognition among cancer survivors postchemotherapy compared with healthy controls","author":"Wang","year":"2015","journal-title":"Cancer"},{"issue":"11 Suppl 3","key":"10.1016\/j.nicl.2017.03.004_bb0245","first-page":"S54","article-title":"Cognition assessment using the NIH toolbox","volume":"80","author":"Weintraub","year":"2013","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.nicl.2017.03.004_bb0250","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.neuroimage.2005.06.053","article-title":"An improved theoretical P value for SPMs based on discrete local maxima","volume":"28","author":"Worsley","year":"2005","journal-title":"NeuroImage"},{"issue":"3","key":"10.1016\/j.nicl.2017.03.004_bb0255","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1210\/en.2009-0254","article-title":"Aromatase inhibitors induce spine synapse loss in the hippocampus of ovariectomized mice","volume":"151","author":"Zhou","year":"2010","journal-title":"Endocrinology"}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158217300633?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158217300633?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:06:22Z","timestamp":1761969982000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158217300633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":56,"alternative-id":["S2213158217300633"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2017.03.004","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Subtle hippocampal deformities in breast cancer survivors with reduced episodic memory and self-reported cognitive concerns","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2017.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}