{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:31:12Z","timestamp":1790339472725,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T00:00:00Z","timestamp":1495670400000},"content-version":"vor","delay-in-days":144,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1016\/j.nicl.2017.05.020","type":"journal-article","created":{"date-parts":[[2017,5,25]],"date-time":"2017-05-25T15:30:48Z","timestamp":1495726248000},"page":"408-414","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"special_numbering":"C","title":["Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging"],"prefix":"10.1016","volume":"15","author":[{"given":"Patrizia","family":"Vannini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Hanseeuw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine E.","family":"Munro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca E.","family":"Amariglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gad A.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorene M.","family":"Rentz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Pascual-Leone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reisa A.","family":"Sperling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nicl.2017.05.020_bb0005","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/13607869856876","article-title":"The heterogeneity of anosognosia for memory impairment in Alzheimer's disease: a review of the literature and a proposed model","volume":"2","author":"Agnew","year":"1998","journal-title":"Aging Ment. Health"},{"key":"10.1016\/j.nicl.2017.05.020_bb0010","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.neuron.2010.02.005","article-title":"Functional-anatomic fractionation of the brain's default network","volume":"65","author":"Andrews-Hanna","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.nicl.2017.05.020_bb0015","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/j.neuroimage.2005.09.058","article-title":"Understanding metamemory: neural correlates of the cognitive process and subjective level of confidence in recognition memory","volume":"29","author":"Chua","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0020","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1016\/j.neuroimage.2009.10.090","article-title":"Topological FDR for neuroimaging","volume":"15","author":"Chumbley","year":"2010","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0025","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.3233\/JAD-150141","article-title":"For a cognitive model of subjective memory awareness","volume":"48","author":"Dalla Barba","year":"2015","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nicl.2017.05.020_bb0030","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\"Mini-mental state\": a practical method for grading cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.nicl.2017.05.020_bb0035","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1006\/nimg.2001.0869","article-title":"Motion correction algorithms may create spurious brain activations in the absence of subject motion","volume":"14","author":"Freire","year":"2001","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0040","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/gps.2583","article-title":"Anosognosia for memory deficit in amnestic mild cognitive impairment and Alzheimer's disease","volume":"26","author":"Galeone","year":"2011","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.nicl.2017.05.020_bb0045","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1037\/0882-7974.5.4.482","article-title":"The memory functioning questionnaire for assessment of memory complaints in adulthood and old age","volume":"5","author":"Gilewski","year":"1990","journal-title":"Psychol. Aging"},{"key":"10.1016\/j.nicl.2017.05.020_bb0050","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3233\/JAD-160204","article-title":"Patients with amyloid-negative mild cognitive impairment have cortical Hypometabolism but the hippocampus is preserved","volume":"53","author":"Hanseeuw","year":"2016","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.nicl.2017.05.020_bb0055","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1097\/00019442-200511000-00003","article-title":"Frontal lobe hypometabolism and impaired insight in Alzheimer disease","volume":"13","author":"Harwood","year":"2005","journal-title":"Am. J. Geriatr. Psychiatr."},{"key":"10.1016\/j.nicl.2017.05.020_bb9015","series-title":"The Study of Anosognosia","first-page":"407","article-title":"Functional Imaging of Self-Appraisal","author":"Johnson","year":"2010"},{"key":"10.1016\/j.nicl.2017.05.020_bb0060","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000084704","article-title":"Anosognosia in very mild Alzheimer's disease but not in mild cognitive impairment","volume":"19","author":"Kalbe","year":"2005","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.nicl.2017.05.020_bb0065","series-title":"The Study of Anosognosia","first-page":"189","article-title":"Anosognosia and Alzheimer's disease: behavioral studies","author":"Kaszniak","year":"2010"},{"key":"10.1016\/j.nicl.2017.05.020_bb0070","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1136\/jnnp.2003.030007","article-title":"Right subiculum amyloid plaque density correlates with anosognosia in Alzheimer's disease","volume":"75","author":"Marshall","year":"2004","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.nicl.2017.05.020_bb0075","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"The clinical dementia rating (CDR): current version and scoring rules","volume":"43","author":"Morris","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.nicl.2017.05.020_bb0080","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.biopsych.2007.05.030","article-title":"Hypometabolism and altered cerebrospinal fluid markers in normal Apolipoprotein E E4 carriers with subjective memory complaints","volume":"63","author":"Mosconi","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nicl.2017.05.020_bb9020","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.tics.2004.01.004","article-title":"Cortical midline structures and the self","volume":"8","author":"Northoff","year":"2004","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.nicl.2017.05.020_bb9025","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.neuroimage.2005.12.002","article-title":"Self-referential processing in our brain: a meta-analysis of imaging studies on the self","volume":"3","author":"Northoff","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0085","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1097\/00002093-199601020-00003","article-title":"Impaired awareness of deficits in Alzheimer disease","volume":"10","author":"Ott","year":"1996","journal-title":"Alzheimer Dis. Assoc. Disord."},{"key":"10.1016\/j.nicl.2017.05.020_bb0090","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1176\/jnp.8.1.41","article-title":"Apathy and loss of insight in Alzheimer's disease: a SPECT imaging study","volume":"8","author":"Ott","year":"1996","journal-title":"J. Neuropsychiatr. Clin. Neurosci."},{"key":"10.1016\/j.nicl.2017.05.020_bb0095","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/ana.24462","article-title":"Anosognosia in Alzheimer disease: disconnection between memory and self-related brain networks","volume":"78","author":"Perrotin","year":"2015","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nicl.2017.05.020_bb0100","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/01688639308402560","article-title":"Anosognosia in Alzheimer's disease: relationships to depression, cognitive function, and cerebral perfusion","volume":"15","author":"Reed","year":"1993","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"10.1016\/j.nicl.2017.05.020_bb0105","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1017\/S1355617707070488","article-title":"Anosognosia in mild cognitive impairment: relationship to activation of cortical midline structures involved in self-appraisal","volume":"13","author":"Ries","year":"2007","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.nicl.2017.05.020_bb0110","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.neuropsychologia.2011.12.014","article-title":"Medial prefrontal functional connectivity - relation to memory self-appraisal accuracy in older adults with and without memory disorders","volume":"50","author":"Ries","year":"2012","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.nicl.2017.05.020_bb0115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1159\/000234911","article-title":"Subjective memory complaints and awareness of memory functioning in mild cognitive impairment: a systematic review","volume":"28","author":"Roberts","year":"2009","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.nicl.2017.05.020_bb0120","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/ana.410070516","article-title":"Pathological verification of ischemic score in differentiation of dementias","volume":"7","author":"Rosen","year":"1980","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nicl.2017.05.020_bb0125","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/j.neurobiolaging.2007.12.014","article-title":"Perspective taking to assess self-personality: What's modified in Alzheimer's disease?","volume":"30","author":"Ruby","year":"2009","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.nicl.2017.05.020_bb0130","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/hbm.20203","article-title":"Neural correlates of anosognosia for cognitive impairment in Alzheimer's disease","volume":"27","author":"Salmon","year":"2006","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2017.05.020_bb9030","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.neubiorev.2006.12.003","article-title":"Relevance to self: A brief review and framework of neural systems underlying appraisal","volume":"31","author":"Schmitz","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nicl.2017.05.020_bb0135","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.neuroscience.2008.08.014","article-title":"The resting brain and our self: self-relatedness modulates resting state neural activity in cortical midline structures","volume":"157","author":"Schneider","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.nicl.2017.05.020_bb0140","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/j.1471-4159.1977.tb10649.x","article-title":"The 14-C deoxyglucose method for the measurement of local cerebral glucose utilization, theory, procedure and normal values in the conscious and anasthetized albino rat","volume":"28","author":"Sokoloff","year":"1977","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nicl.2017.05.020_bb0145","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cortex.2014.07.019","article-title":"Anosognosia in Alzheimer's disease: diagnosis, frequency, mechanism and clinical correlates","volume":"61","author":"Starkstein","year":"2014","journal-title":"Cortex"},{"key":"10.1016\/j.nicl.2017.05.020_bb0150","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1001\/archneur.1995.00540280105024","article-title":"A single photon emission computed tomographic study of anosognosia in Alzheimer's disease","volume":"52","author":"Starkstein","year":"1995","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.nicl.2017.05.020_bb0155","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1016\/j.neuropsychologia.2006.05.023","article-title":"The functional neuroanatomy of autobiographical memory: a meta-analysis","volume":"44","author":"Svoboda","year":"2006","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.nicl.2017.05.020_bb0160","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1152\/jn.00783.2009","article-title":"Intrinsic functional connectivity as a tool for human Connectomics: theory, properties, and optimization","volume":"103","author":"Van Dijk","year":"2010","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.nicl.2017.05.020_bb0165","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.neuropsychologia.2017.04.002","article-title":"Memory Self-Awareness in the Preclinical and Prodromal Stages of Alzheimer's Disease","volume":"99","author":"Vannini","year":"2017","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.nicl.2017.05.020_bb0170","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1212\/WNL.0000000000003889","article-title":"Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden","volume":"88","author":"Vannini","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.nicl.2017.05.020_bb0175","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1093\/brain\/awq203","article-title":"Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease","volume":"133","author":"Villain","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2017.05.020_bb0180","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/gps.1272","article-title":"Cognitive and functional neuroimaging correlate for anosognosia in mild cognitive impairment and Alzheimer's disease","volume":"20","author":"Vogel","year":"2005","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.nicl.2017.05.020_bb0185","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.tics.2005.07.001","article-title":"Parietal lobe contributions to episodic memory retrieval","volume":"9","author":"Wagner","year":"2005","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.nicl.2017.05.020_bb0190","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.neuroimage.2005.12.033","article-title":"Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI","volume":"31","author":"Wang","year":"2010","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0195","series-title":"WMS-R Wechsler Memory Scale-revised Manual","author":"Wechsler","year":"1987"},{"key":"10.1016\/j.nicl.2017.05.020_bb0200","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.neuroimage.2003.11.001","article-title":"Functional-anatomical correlates of remembering and knowing","volume":"21","author":"Wheeler","year":"2004","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2017.05.020_bb0205","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.neuroimage.2010.11.048","article-title":"Associations and dissociations between default and self-reference networks in the human brain","volume":"55","author":"Whitfield-Gabrieli","year":"2011","journal-title":"NeuroImage"}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158217301262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158217301262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:15:19Z","timestamp":1761970519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158217301262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":45,"alternative-id":["S2213158217301262"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2017.05.020","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2017.05.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}