{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:27:16Z","timestamp":1790695636472,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T00:00:00Z","timestamp":1516665600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EB021265"],"award-info":[{"award-number":["EB021265"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS042861"],"award-info":[{"award-number":["NS042861"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NR10827"],"award-info":[{"award-number":["R01NR10827"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS058793"],"award-info":[{"award-number":["NS058793"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["EB006758"],"award-info":[{"award-number":["EB006758"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P41RR14075"],"award-info":[{"award-number":["P41RR14075"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/j.nicl.2018.01.029","type":"journal-article","created":{"date-parts":[[2018,2,19]],"date-time":"2018-02-19T12:37:26Z","timestamp":1519043846000},"page":"236-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"special_numbering":"C","title":["Complex spatial and temporally defined myelin and axonal degeneration in Huntington disease"],"prefix":"10.1016","volume":"20","author":[{"given":"H.D.","family":"Rosas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Wilkens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.H.","family":"Salat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.D.","family":"Mercaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vangel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.Y.","family":"Yendiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Hersch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.nicl.2018.01.029_bb0005","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1148\/radiol.10101284","article-title":"White matter damage in Alzheimer disease and its relationship to gray matter atrophy","volume":"258","author":"Agosta","year":"2011","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.nicl.2018.01.029_bb0010","first-page":"1399","article-title":"Proton MR spectroscopy for the evaluation of brain injury in asphyxiated, term neonates","volume":"20","author":"Barkovich","year":"1999","journal-title":"AJNR Am. J. Neuroradiol."},{"issue":"10","key":"10.1016\/j.nicl.2018.01.029_bb0015","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1007\/s11064-007-9352-7","article-title":"Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications","volume":"32","author":"Bartzokis","year":"2007","journal-title":"Neurochem. Res."},{"issue":"3","key":"10.1016\/j.nicl.2018.01.029_bb0020","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1006\/jmrb.1996.0086","article-title":"Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI","volume":"111","author":"Basser","year":"1996","journal-title":"J. Magn. Reson. Ser. B"},{"issue":"Series B","key":"10.1016\/j.nicl.2018.01.029_bb0025","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practival and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc."},{"issue":"3","key":"10.1016\/j.nicl.2018.01.029_bb0030","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s11682-011-9121-8","article-title":"Diffusion tensor imaging in Huntington's disease reveals distinct patterns of white matter degeneration associated with motor and cognitive deficits","volume":"5","author":"Bohanna","year":"2011","journal-title":"Brain Imaging Behav."},{"issue":"12","key":"10.1016\/j.nicl.2018.01.029_bb0035","doi-asserted-by":"crossref","first-page":"4690","DOI":"10.1073\/pnas.1113455109","article-title":"Salience network integrity predicts default mode network function after traumatic brain injury","volume":"109","author":"Bonnelle","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0040","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s11065-010-9129-7","article-title":"MR diffusion tensor imaging: a window into white matter integrity of the working brain","volume":"20","author":"Chanraud","year":"2010","journal-title":"Neuropsychol. Rev."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0045","first-page":"215","article-title":"Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease","volume":"47","author":"Ciarmiello","year":"2006","journal-title":"J. Nucl. Med."},{"issue":"4","key":"10.1016\/j.nicl.2018.01.029_bb0050","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/(SICI)1096-9861(19990125)403:4<431::AID-CNE2>3.0.CO;2-1","article-title":"Cortical connections of the frontoparietal opercular areas in the rhesus monkey","volume":"403","author":"Cipolloni","year":"1999","journal-title":"J. Comp. Neurol."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0055","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/ana.410270217","article-title":"Degeneration of pyramidal projection neurons in Huntington's disease cortex","volume":"27","author":"Cudkowicz","year":"1990","journal-title":"Ann. Neurol."},{"issue":"Pt 12","key":"10.1016\/j.nicl.2018.01.029_bb0060","doi-asserted-by":"crossref","first-page":"3137","DOI":"10.1093\/brain\/aww241","article-title":"Disconnection between the default mode network and medial temporal lobes in post-traumatic amnesia","volume":"139","author":"De Simoni","year":"2016","journal-title":"Brain"},{"issue":"9","key":"10.1016\/j.nicl.2018.01.029_bb0065","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1002\/hbm.22055","article-title":"The structural correlates of functional deficits in early Huntington's disease","volume":"34","author":"Delmaire","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2018.01.029_bb0070","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3389\/fnins.2016.00457","article-title":"Impaired levels of gangliosides in the corpus callosum of Huntington disease animal models","volume":"10","author":"Di Pardo","year":"2016","journal-title":"Front. Neurosci."},{"issue":"5334","key":"10.1016\/j.nicl.2018.01.029_bb0075","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1126\/science.277.5334.1990","article-title":"Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain","volume":"277","author":"DiFiglia","year":"1997","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.nicl.2018.01.029_bb0080","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/hbm.21205","article-title":"Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease","volume":"33","author":"Dumas","year":"2012","journal-title":"Hum. Brain Mapp."},{"issue":"7","key":"10.1016\/j.nicl.2018.01.029_bb0085","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.tins.2008.04.001","article-title":"White matter in learning, cognition and psychiatric disorders","volume":"31","author":"Fields","year":"2008","journal-title":"Trends Neurosci."},{"issue":"8","key":"10.1016\/j.nicl.2018.01.029_bb0090","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/j.1469-8749.2010.03633.x","article-title":"Superior longitudinal fasciculus and cognitive dysfunction in adolescents born preterm and at term","volume":"52","author":"Frye","year":"2010","journal-title":"Dev. Med. Child Neurol."},{"issue":"18","key":"10.1016\/j.nicl.2018.01.029_bb0095","doi-asserted-by":"crossref","first-page":"5285","DOI":"10.1093\/hmg\/ddv248","article-title":"Analysis of YFP(J16)-R6\/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease","volume":"24","author":"Gatto","year":"2015","journal-title":"Hum. Mol. Genet."},{"issue":"4","key":"10.1016\/j.nicl.2018.01.029_bb0100","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1006\/nimg.2001.1037","article-title":"Thresholding of statistical maps in functional neuroimaging using the false discovery rate","volume":"15","author":"Genovese","year":"2002","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.nicl.2018.01.029_bb0105","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve","year":"2009","journal-title":"NeuroImage"},{"issue":"44","key":"10.1016\/j.nicl.2018.01.029_bb0110","doi-asserted-by":"crossref","first-page":"11960","DOI":"10.1523\/JNEUROSCI.3591-07.2007","article-title":"More is not always better: increased fractional anisotropy of superior longitudinal fasciculus associated with poor visuospatial abilities in Williams syndrome","volume":"27","author":"Hoeft","year":"2007","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.nicl.2018.01.029_bb0115","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.neuron.2015.02.026","article-title":"Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes","volume":"85","author":"Huang","year":"2015","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.nicl.2018.01.029_bb0120","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuron.2006.02.006","article-title":"Astrocytes promote myelination in response to electrical impulses","volume":"49","author":"Ishibashi","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.nicl.2018.01.029_bb0125","first-page":"969","volume":"12","author":"Kabukcu Basay","year":"2016","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"5","key":"10.1016\/j.nicl.2018.01.029_bb0130","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.biopsych.2007.06.017","article-title":"Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia","volume":"63","author":"Karlsgodt","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.nicl.2018.01.029_bb0135","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1192\/bjp.bp.110.081836","article-title":"Neural activation and radial diffusivity in schizophrenia: combined fMRI and diffusion tensor imaging study","volume":"198","author":"Koch","year":"2011","journal-title":"Br. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0140","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/ajmg.b.30992","article-title":"CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches","volume":"153B","author":"Langbehn","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.nicl.2018.01.029_bb0145","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuroscience.2015.05.049","article-title":"Tract-based analysis of white matter degeneration in Alzheimer's disease","volume":"301","author":"Lee","year":"2015","journal-title":"Neuroscience"},{"issue":"21","key":"10.1016\/j.nicl.2018.01.029_bb0150","doi-asserted-by":"crossref","first-page":"8473","DOI":"10.1523\/JNEUROSCI.21-21-08473.2001","article-title":"Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice","volume":"21","author":"Li","year":"2001","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.nicl.2018.01.029_bb0155","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/j.1365-2990.1997.tb01326.x","article-title":"Significant loss of pyramidal neurons in the angular gyrus of patients with Huntington's disease","volume":"23","author":"Macdonald","year":"1997","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.nicl.2018.01.029_bb0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brainres.2014.03.012","article-title":"Superior longitudinal fasciculus and language functioning in healthy aging","volume":"1562","author":"Madhavan","year":"2014","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.nicl.2018.01.029_bb0165","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1093\/cercor\/bhh186","article-title":"Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study","volume":"15","author":"Makris","year":"2005","journal-title":"Cereb. Cortex"},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0170","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.pscychresns.2010.04.013","article-title":"Anterior thalamic radiation integrity in schizophrenia: a diffusion-tensor imaging study","volume":"183","author":"Mamah","year":"2010","journal-title":"Psychiatry Res."},{"issue":"4","key":"10.1016\/j.nicl.2018.01.029_bb0175","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1002\/hbm.22273","article-title":"Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease","volume":"35","author":"Matsui","year":"2014","journal-title":"Hum. Brain Mapp."},{"issue":"1","key":"10.1016\/j.nicl.2018.01.029_bb0180","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/cne.902250105","article-title":"Some observations on the course and composition of the cingulum bundle in the rhesus monkey","volume":"225","author":"Mufson","year":"1984","journal-title":"J. Comp. Neurol."},{"issue":"40","key":"10.1016\/j.nicl.2018.01.029_bb0185","doi-asserted-by":"crossref","first-page":"10456","DOI":"10.1523\/JNEUROSCI.0741-16.2016","article-title":"Impact of visual Corticostriatal loop disruption on neural processing within the parahippocampal place area","volume":"36","author":"Nasr","year":"2016","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.nicl.2018.01.029_bb0190","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/mds.25864","article-title":"The cognitive burden in Huntington's disease: pathology, phenotype, and mechanisms of compensation","volume":"29","author":"Papoutsi","year":"2014","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nicl.2018.01.029_bb0195","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/B978-0-12-801893-4.00006-7","article-title":"Cognitive and behavioral changes in Huntington disease before diagnosis","volume":"144","author":"Paulsen","year":"2017","journal-title":"Handb. Clin. Neurol."},{"issue":"6 Pt 1","key":"10.1016\/j.nicl.2018.01.029_bb0200","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1006\/nimg.2001.0765","article-title":"Water diffusion changes in Wallerian degeneration and their dependence on white matter architecture","volume":"13","author":"Pierpaoli","year":"2001","journal-title":"NeuroImage"},{"issue":"12","key":"10.1016\/j.nicl.2018.01.029_bb0205","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1002\/hbm.20978","article-title":"Assessment of white matter tract damage in mild cognitive impairment and Alzheimer's disease","volume":"31","author":"Pievani","year":"2010","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2018.01.029_bb0210","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.nbd.2014.01.013","article-title":"White matter connectivity reflects clinical and cognitive status in Huntington's disease","volume":"65","author":"Poudel","year":"2014","journal-title":"Neurobiol. Dis."},{"issue":"9","key":"10.1016\/j.nicl.2018.01.029_bb0215","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/mds.20979","article-title":"Diffusion tensor imaging in presymptomatic and early Huntington's disease: selective white matter pathology and its relationship to clinical measures","volume":"21","author":"Rosas","year":"2006","journal-title":"Mov. Disord."},{"key":"10.1016\/j.nicl.2018.01.029_bb0220","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1196\/annals.1427.034","article-title":"Complexity and heterogeneity: what drives the ever-changing brain in Huntington's disease?","volume":"1147","author":"Rosas","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"Pt 4","key":"10.1016\/j.nicl.2018.01.029_bb0225","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1093\/brain\/awn025","article-title":"Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity","volume":"131","author":"Rosas","year":"2008","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.nicl.2018.01.029_bb0230","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1016\/j.neuroimage.2009.10.015","article-title":"Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical \u201cdisconnection\u201d","volume":"49","author":"Rosas","year":"2010","journal-title":"NeuroImage"},{"issue":"9","key":"10.1016\/j.nicl.2018.01.029_bb0235","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1002\/mds.23762","article-title":"A tale of two factors: what determines the rate of progression in Huntington's disease? A longitudinal MRI study","volume":"26","author":"Rosas","year":"2011","journal-title":"Mov. Disord."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0240","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/00005072-199902000-00006","article-title":"Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease","volume":"58","author":"Sapp","year":"1999","journal-title":"J. Neuropathol. Exp. Neurol."},{"issue":"3","key":"10.1016\/j.nicl.2018.01.029_bb0245","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.neuroimage.2003.07.005","article-title":"Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia","volume":"20","author":"Song","year":"2003","journal-title":"NeuroImage"},{"issue":"13","key":"10.1016\/j.nicl.2018.01.029_bb0250","first-page":"2621","article-title":"Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease","volume":"25","author":"Teo","year":"2016","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0255","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1017\/S1355617715001009","article-title":"Variation in white matter connectivity predicts the ability to remember faces and discriminate their emotions","volume":"22","author":"Unger","year":"2016","journal-title":"J. Int. Neuropsychol. Soc."},{"issue":"2","key":"10.1016\/j.nicl.2018.01.029_bb0260","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1111\/ejn.12575","article-title":"Visual system integrity and cognition in early Huntington's disease","volume":"40","author":"Wolf","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.nicl.2018.01.029_bb0265","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3389\/fninf.2011.00023","article-title":"Automated probabilistic reconstruction of white-matter pathways in health and disease using an atlas of the underlying anatomy","volume":"5","author":"Yendiki","year":"2011","journal-title":"Front. Neuroinform."},{"key":"10.1016\/j.nicl.2018.01.029_bb0270","first-page":"4530","article-title":"A probabilistic method for unbiased longitudinal tractography with application to Huntington's disease","volume":"2014","author":"Yendiki","year":"2014","journal-title":"Proc. Int. Soc. Magn. Reson. Med."},{"issue":"6","key":"10.1016\/j.nicl.2018.01.029_bb0275","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1523\/JNEUROSCI.23-06-02193.2003","article-title":"Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease","volume":"23","author":"Yu","year":"2003","journal-title":"J. Neurosci."}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218300299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218300299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:13:13Z","timestamp":1761970393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158218300299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":55,"alternative-id":["S2213158218300299"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2018.01.029","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Complex spatial and temporally defined myelin and axonal degeneration in Huntington disease","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2018.01.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}