{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T21:02:33Z","timestamp":1780952553062,"version":"3.54.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T00:00:00Z","timestamp":1521590400000},"content-version":"vor","delay-in-days":79,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["K05AA00219"],"award-info":[{"award-number":["K05AA00219"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["R01AA07112"],"award-info":[{"award-number":["R01AA07112"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R21DA042271"],"award-info":[{"award-number":["R21DA042271"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R21NS079905"],"award-info":[{"award-number":["R21NS079905"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R21NS077059"],"award-info":[{"award-number":["R21NS077059"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH102377"],"award-info":[{"award-number":["R01MH102377"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH111917"],"award-info":[{"award-number":["R01MH111917"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008460","name":"National Center for Complementary and Integrative Health","doi-asserted-by":"publisher","award":["R21AT008865"],"award-info":[{"award-number":["R21AT008865"]}],"id":[{"id":"10.13039\/100008460","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG042512"],"award-info":[{"award-number":["R01AG042512"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/j.nicl.2018.03.025","type":"journal-article","created":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T17:44:49Z","timestamp":1521740689000},"page":"98-105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Sexually dimorphic structural abnormalities in major connections of the medial forebrain bundle in alcoholism"],"prefix":"10.1016","volume":"19","author":[{"given":"Ana Mar\u00eda","family":"Rivas-Grajales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayle S.","family":"Sawyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarina","family":"Karmacharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Papadimitriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan A.","family":"Camprodon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon J.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Kubicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene","family":"Oscar-Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos","family":"Makris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nicl.2018.03.025_bb0005","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.nurt.2007.05.011","article-title":"Diffusion tensor imaging of the brain","volume":"4","author":"Alexander","year":"2007","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.nicl.2018.03.025_bb0010","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"10.1016\/j.nicl.2018.03.025_bb0015","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.media.2007.06.004","article-title":"Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain","volume":"12","author":"Avants","year":"2008","journal-title":"Med. Image Anal."},{"key":"10.1016\/j.nicl.2018.03.025_bb0020","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0361-9230(99)00245-2","article-title":"Connections underlying the synthesis of cognition, memory, and emotion in primate prefrontal cortices","volume":"52","author":"Barbas","year":"2000","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.nicl.2018.03.025_bb0025","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jmr.2011.09.022","article-title":"Analysis of partial volume effects in diffusion-tensor MRI","volume":"213","author":"Basser","year":"2011","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.nicl.2018.03.025_bb0030","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00213-006-0578-x","article-title":"The debate over dopamine's role in reward: the case for incentive salience","volume":"191","author":"Berridge","year":"2007","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0035","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.coph.2008.12.014","article-title":"Dissecting components of reward: \u2018liking\u2019, \u2018wanting\u2019, and learning","volume":"9","author":"Berridge","year":"2009","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.nicl.2018.03.025_bb0040","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1742-4682-5-24","article-title":"Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary","volume":"5","author":"Blum","year":"2008","journal-title":"Theory Biol. Med. Model."},{"key":"10.1016\/j.nicl.2018.03.025_bb0045","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/ajmg.b.30080","article-title":"Relationship between dopaminergic neurotransmission, alcoholism, and reward deficiency syndrome","volume":"132B","author":"Bowirrat","year":"2005","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.nicl.2018.03.025_bb0050","series-title":"American Drinking Practices: A National Study of Drinking Behavior and Attitudes (Monograph no. 6). Publications Division, Rutgers Center of Alcohol Studies. New Brunswick, NJ","author":"Cahalan","year":"1969"},{"key":"10.1016\/j.nicl.2018.03.025_bb0055","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00213-006-0600-3","article-title":"Regulation of intravenous cocaine self-administration in rats selectively bred for high (HiS) and low (LoS) saccharin intake","volume":"190","author":"Carroll","year":"2006","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0060","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1093\/brain\/awh622","article-title":"The rises and falls of disconnection syndromes","volume":"128","author":"Catani","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.03.025_bb0065","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/npp.2008.101","article-title":"Diffusion tensor tractography in mesencephalic bundles: relation to mental flexibility in detoxified alcohol-dependent subjects","volume":"34","author":"Chanraud","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0070","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1176\/appi.neuropsych.11080180","article-title":"Human medial forebrain bundle (MFB) and anterior thalamic radiation (ATR): Imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression","volume":"24","author":"Coenen","year":"2012","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.nicl.2018.03.025_bb0075","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1017\/S1092852916000286","article-title":"The medial forebrain bundle as a target for deep brain stimulation for obsessive-compulsive disorder","volume":"22","author":"Coenen","year":"2016","journal-title":"CNS Spectr."},{"key":"10.1016\/j.nicl.2018.03.025_bb0080","first-page":"432","article-title":"Dopamine for \u201cwanting\u201d and opioids for \u201cliking\u201d: a comparison of obese adults with and without binge eating","volume":"91","author":"Davis","year":"2009","journal-title":"Obesity"},{"key":"10.1016\/j.nicl.2018.03.025_bb0085","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.03.025_bb0090","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.neubiorev.2014.11.018","article-title":"Electrical stimulation of the medial forebrain bundle in pre-clinical studies of psychiatric disorders","volume":"49","author":"D\u00f6br\u00f6ssy","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nicl.2018.03.025_bb0095","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1111\/acer.12140","article-title":"Neurocognition in 1-month-abstinent treatment-seeking alcohol-dependent individuals: interactive effects of age and chronic cigarette smoking","volume":"37","author":"Durazzo","year":"2013","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0100","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","article-title":"Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain","volume":"33","author":"Fischl","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.nicl.2018.03.025_bb0105","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/10673220902899680","article-title":"Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women","volume":"17","author":"Fox","year":"2009","journal-title":"Harvard Rev. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.pnpbp.2014.12.003","article-title":"The medial forebrain bundle as a deep brain stimulation target for treatment resistant depression: a review of published data","volume":"58","author":"G\u00e1lvez","year":"2015","journal-title":"Progr. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2015.00139","article-title":"Visualization of the medial forebrain bundle using diffusion tensor imaging","volume":"9","author":"Hana","year":"2015","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.nicl.2018.03.025_bb0120","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0278-5846(03)00155-6","article-title":"Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre","volume":"27","author":"Harper","year":"2003","journal-title":"Progr. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0125","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1530-0277.2008.00661.x","article-title":"Frontal white matter and cingulum diffusion tensor imaging deficits in alcoholism","volume":"32","author":"Harris","year":"2008","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0130","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.neubiorev.2005.06.006","article-title":"The limbic lobe and its output channels: implications for emotional functions and adaptive behavior","volume":"30","author":"Heimer","year":"2006","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.nicl.2018.03.025_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0036572","article-title":"Deep brain stimulation of nucleus accumbens region in alcoholism affects reward processing","volume":"7","author":"Heldmann","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nicl.2018.03.025_bb0140","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1176\/appi.ajp.158.2.198","article-title":"Evidence for a gender-related effect of alcoholism on brain volumes","volume":"158","author":"Hommer","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0145","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.alcohol.2016.07.007","article-title":"Sex differences in the behavioral sequelae of chronic ethanol exposure","volume":"58","author":"Jury","year":"2017","journal-title":"Alcohol"},{"key":"10.1016\/j.nicl.2018.03.025_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2013.00072","article-title":"Addiction is a reward deficit and stress surfeit disorder","volume":"4","author":"Koob","year":"2013","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0155","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/npp.2009.110","article-title":"Neurocircuitry of addiction","volume":"35","author":"Koob","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0160","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1136\/jnnp.2006.113092","article-title":"Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?","volume":"78","author":"Kuhn","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0165","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1111\/j.1369-1600.2011.00337.x","article-title":"Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring","volume":"16","author":"Kuhn","year":"2011","journal-title":"Addict. Biol."},{"key":"10.1016\/j.nicl.2018.03.025_bb0170","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1369-1600.2007.00088.x","article-title":"Chronic deep brain stimulation in the rat nucleus accumbens and its effect on morphine reinforcement","volume":"13","author":"Liu","year":"2008","journal-title":"Addict. Biol."},{"key":"10.1016\/j.nicl.2018.03.025_bb0175","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.2147\/NDT.S52298","article-title":"Brain volumes and neuropsychological performance are related to current smoking and alcoholism history","volume":"9","author":"Luhar","year":"2013","journal-title":"Neuropsychiatric Dis. Treat."},{"key":"10.1016\/j.nicl.2018.03.025_bb0180","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.biopsych.2008.01.018","article-title":"Decreased volume of the brain reward system in alcoholism","volume":"64","author":"Makris","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0185","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1109\/TMI.2010.2048121","article-title":"Filtered multitensor tractography","volume":"29","author":"Malcolm","year":"2010","journal-title":"IEEE Trans. Med. Imaging"},{"key":"10.1016\/j.nicl.2018.03.025_bb0190","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1111\/j.1530-0277.2009.00953.x","article-title":"Altered white matter integrity in adolescent binge drinkers","volume":"33","author":"McQueeny","year":"2009","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0195","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1001\/archneur.1988.00520330076013","article-title":"Disproportionate atrophy of cerebral white matter in chronic alcoholics","volume":"45","author":"de la Monte","year":"1988","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.nicl.2018.03.025_bb0200","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1055\/s-0029-1233489","article-title":"Successful treatment of chronic resistant alcoholism by deep brain stimulation of nucleus accumbens: first experience with three cases","volume":"42","author":"M\u00fcller","year":"2009","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0205","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/cne.902060106","article-title":"The medial forebrain bundle of the rat. I. General introduction","volume":"206","author":"Nieuwenhuys","year":"1982","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.nicl.2018.03.025_bb0210","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1530-0277.1996.tb01637.x","article-title":"Gender difference in alcohol-evoked hypothalamic-pituitary-adrenal activity in the rat: ontogeny and role of neonatal steroids","volume":"20","author":"Ogilvie","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0215","first-page":"211","article-title":"Genetic influences in emotional dysfunction and alcoholism-related brain damage","volume":"1","author":"Oscar-Berman","year":"2005","journal-title":"Neuropsychiatric Dis. Treat."},{"key":"10.1016\/j.nicl.2018.03.025_bb0220","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s11065-007-9038-6","article-title":"Alcohol: effects on neurobehavioral functions and the brain","volume":"17","author":"Oscar-Berman","year":"2007","journal-title":"Neuropsychol. Rev."},{"key":"10.1016\/j.nicl.2018.03.025_bb0225","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2147\/NDT.S13405","article-title":"Brain volumetric measures in alcoholics: a comparison of two segmentation methods","volume":"7","author":"Oscar-Berman","year":"2011","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.nicl.2018.03.025_bb0230","series-title":"Alcohol and the Nervous System, Handbook of Clinical Neurology","first-page":"183","article-title":"Profiles of impaired, spared, and recovered neuropsychologic processes in alcoholism","author":"Oscar-Berman","year":"2014"},{"key":"10.1016\/j.nicl.2018.03.025_bb0235","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/sj.npp.1300623","article-title":"Disruption of brain white matter microstructure by excessive intracellular and extracellular fluid in alcoholism: evidence from diffusion tensor imaging","volume":"30","author":"Pfefferbaum","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0240","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1176\/appi.ajp.158.2.188","article-title":"Sex differences in the effects of alcohol on brain structure","volume":"158","author":"Pfefferbaum","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0245","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.biopsych.2008.10.039","article-title":"Degradation of association and projection white matter systems in alcoholism detected with quantitative fiber tracking","volume":"65","author":"Pfefferbaum","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.nicl.2018.03.025_bb0250","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00213-013-3214-6","article-title":"Deep brain stimulation for the treatment of addiction: basic and clinical studies and potential mechanisms of action","volume":"229","author":"Pierce","year":"2013","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0255","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/jon.12313","article-title":"A new MRI masking technique based on multi-atlas brain segmentation in controls and schizophrenia: a rapid and viable alternative to manual masking","volume":"26","author":"del Re","year":"2015","journal-title":"J. Neuroimaging"},{"key":"10.1016\/j.nicl.2018.03.025_bb0260","series-title":"NIMH Diagnostic Interview Schedule: Version III Revised (DIS-III-R). St. Louis, MO","author":"Robins","year":"1989"},{"key":"10.1016\/j.nicl.2018.03.025_bb0265","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1037\/0735-7044.119.1.5","article-title":"Distinguishing whether dopamine regulates liking, wanting, and\/or learning about rewards","volume":"119","author":"Robinson","year":"2005","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.nicl.2018.03.025_bb0270","article-title":"Closing the gender gap: the case for gender-specific alcoholism research","volume":"1","author":"Ruiz","year":"2013","journal-title":"J. Alcohol. Drug Depend."},{"key":"10.1016\/j.nicl.2018.03.025_bb0275","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1530-0277.2012.01862.x","article-title":"Drinking history associations with regional white matter volumes in alcoholic men and women","volume":"37","author":"Ruiz","year":"2012","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0280","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.neuroimage.2008.10.030","article-title":"Regional white matter volume differences in nondemented aging and Alzheimer's disease","volume":"44","author":"Salat","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.03.025_bb0285","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.drugalcdep.2014.10.006","article-title":"Characterizing white matter changes in cigarette smokers via diffusion tensor imaging","volume":"145","author":"Savjani","year":"2014","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.nicl.2018.03.025_bb0290","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1111\/acer.13074","article-title":"Associations between cerebellar subregional morphometry and alcoholism history in men and women","volume":"40","author":"Sawyer","year":"2016","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0295","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pscychresns.2017.03.001","article-title":"Gender dimorphism of brain reward system volumes in alcoholism","volume":"263","author":"Sawyer","year":"2017","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.nicl.2018.03.025_bb0300","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1002\/hbm.22808","article-title":"Integrity of white matter microstructure in alcoholics with and without Korsakoff's syndrome","volume":"36","author":"Segobin","year":"2015","journal-title":"Hum. Brain Mapp"},{"key":"10.1016\/j.nicl.2018.03.025_bb0305","first-page":"1","article-title":"Alcoholism and sexual dimorphism in the middle longitudinal fascicle: a pilot study","volume":"35","author":"Seitz","year":"2016","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.nicl.2018.03.025_bb0310","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.neuroimage.2003.07.005","article-title":"Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia","volume":"20","author":"Song","year":"2003","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.03.025_bb0315","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00213-011-2500-4","article-title":"Binge drinking differentially affects adolescent male and female brain morphometry","volume":"220","author":"Squeglia","year":"2012","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.nicl.2018.03.025_bb0320","first-page":"127","article-title":"Alcohol's effects on brain and behavior","volume":"33","author":"Sullivan","year":"2010","journal-title":"Alcohol Res. Health"},{"key":"10.1016\/j.nicl.2018.03.025_bb0325","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/acer.12243","article-title":"Using autopsy brain tissue to study alcohol-related brain damage in the genomic age","volume":"38","author":"Sutherland","year":"2013","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.nicl.2018.03.025_bb0330","doi-asserted-by":"crossref","first-page":"14446","DOI":"10.1523\/JNEUROSCI.4804-12.2013","article-title":"Deep brain stimulation of the nucleus accumbens shell attenuates cocaine reinstatement through local and antidromic activation","volume":"33","author":"Vassoler","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.nicl.2018.03.025_bb0335","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1056\/NEJMra1511480","article-title":"Neurobiologic advances from the brain disease model of addiction","volume":"374","author":"Volkow","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.nicl.2018.03.025_bb0340","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1007\/s00429-015-1179-4","article-title":"The white matter query language: A novel approach for describing human white matter anatomy","volume":"221","author":"Wassermann","year":"2016","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nicl.2018.03.025_bb0345","series-title":"Wechsler Adult Intelligence Scale","author":"Wechsler","year":"1997"},{"key":"10.1016\/j.nicl.2018.03.025_bb0350","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.drugalcdep.2017.01.032","article-title":"Effects of abstinence and chronic cigarette smoking on white matter microstructure in alcohol dependence: diffusion tensor imaging at 4T","volume":"175","author":"Zou","year":"2017","journal-title":"Drug Alcohol Depend."}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218300950?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218300950?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:25:50Z","timestamp":1761971150000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158218300950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":70,"alternative-id":["S2213158218300950"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2018.03.025","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sexually dimorphic structural abnormalities in major connections of the medial forebrain bundle in alcoholism","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2018.03.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}