{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:47:43Z","timestamp":1789732063610,"version":"4.0.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T00:00:00Z","timestamp":1531267200000},"content-version":"vor","delay-in-days":191,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["RD16\/0015\/0003"],"award-info":[{"award-number":["RD16\/0015\/0003"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["RD16\/0015\/0002"],"award-info":[{"award-number":["RD16\/0015\/0002"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["RD12\/0032\/0002"],"award-info":[{"award-number":["RD12\/0032\/0002"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002809","name":"Generalitat de Catalunya","doi-asserted-by":"publisher","award":["RD12\/0060\/01-02"],"award-info":[{"award-number":["RD12\/0060\/01-02"]}],"id":[{"id":"10.13039\/501100002809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Clinical"],"published-print":{"date-parts":[[2018]]},"DOI":"10.1016\/j.nicl.2018.07.012","type":"journal-article","created":{"date-parts":[[2018,7,15]],"date-time":"2018-07-15T02:04:22Z","timestamp":1531620262000},"page":"161-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Magnetic resonance markers of tissue damage related to connectivity disruption in multiple sclerosis"],"prefix":"10.1016","volume":"20","author":[{"given":"Elisabeth","family":"Solana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloy","family":"Martinez-Heras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena H.","family":"Martinez-Lapiscina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Sepulveda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Sola-Valls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Bargall\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Berenguer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magi","family":"Andorra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Pulido-Valdeolivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irati","family":"Zubizarreta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Saiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Llufriu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nicl.2018.07.012_bb0005","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/ana.24202","article-title":"In vivo evidence of glutamate toxicity in multiple sclerosis","volume":"76","author":"Azevedo","year":"2014","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0010","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1002\/hbm.21344","article-title":"Evaluating and reducing the impact of white matter lesions on brain volume measurements","volume":"33","author":"Battaglini","year":"2012","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2018.07.012_bb0015","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1177\/135245850100700409","article-title":"The brief repeatable battery of neuropsychological tests: normative values allow application in multiple sclerosis clinical practice","volume":"7","author":"Boringa","year":"2001","journal-title":"Mult. Scler."},{"key":"10.1016\/j.nicl.2018.07.012_bb0020","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nrn3214","article-title":"The economy of brain network organization","volume":"13","author":"Bullmore","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.nicl.2018.07.012_bb0025","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/jmri.10043","article-title":"Reproducibility of in vivo metabolite quantification with proton magnetic resonance spectroscopic imaging","volume":"15","author":"Chard","year":"2002","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.nicl.2018.07.012_bb0030","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S1474-4422(08)70259-X","article-title":"Cognitive impairment in multiple sclerosis","volume":"7","author":"Chiaravalloti","year":"2008","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/S1474-4422(14)70101-2","article-title":"Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging","author":"Ciccarelli","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0040","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/B978-0-444-52001-2.00005-4","article-title":"Axonal loss in multiple sclerosis: causes and mechanisms","volume":"122","author":"Criste","year":"2014","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0045","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1093\/brain\/awu132","article-title":"The hubs of the human connectome are generally implicated in the anatomy of brain disorders","volume":"137","author":"Crossley","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0050","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1002\/ana.410380610","article-title":"Chemical pathology of acute demyelinating lesions and its correlation with disability","volume":"38","author":"De Stefano","year":"1995","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0055","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0060","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/brain\/awn275","article-title":"Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis","volume":"132","author":"Dineen","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0065","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature09612","article-title":"Regulation of synaptic connectivity by glia","volume":"468","author":"Eroglu","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.nicl.2018.07.012_bb0070","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1177\/1352458512443995","article-title":"The neurologist's dilemma: MS is a grey matter disease that standard clinical and MRI measures cannot assess adequately \u2013 No","volume":"18","author":"Filippi","year":"2012","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.nicl.2018.07.012_bb0075","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S1474-4422(12)70003-0","article-title":"Association between pathological and MRI findings in multiple sclerosis","volume":"11","author":"Filippi","year":"2012","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0080","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1471-4159.2002.01041.x","article-title":"Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance","volume":"82","author":"Fisher","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.nicl.2018.07.012_bb0085","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0090","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1093\/brain\/awv398","article-title":"The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain","volume":"139","author":"Haider","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0095","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.neuroimage.2014.11.039","article-title":"Effective connectivity within the frontoparietal control network differentiates cognitive control and working memory","volume":"106","author":"Harding","year":"2015","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0100","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1093\/brain\/awp089","article-title":"Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load","volume":"132","author":"He","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0105","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00429-012-0498-y","article-title":"Tracing superior longitudinal fasciculus connectivity in the human brain using high resolution diffusion tensor tractography","volume":"219","author":"Kamali","year":"2014","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nicl.2018.07.012_bb0110","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.neuroimage.2011.01.007","article-title":"Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords","volume":"55","author":"Klawiter","year":"2011","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnins.2016.00478","article-title":"Graph theory-based brain connectivity for automatic classification of multiple sclerosis clinical courses","volume":"10","author":"Kocevar","year":"2016","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.nicl.2018.07.012_bb0120","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/nbm.891","article-title":"Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts","volume":"17","author":"Kreis","year":"2004","journal-title":"NMR Biomed."},{"key":"10.1016\/j.nicl.2018.07.012_bb0125","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1212\/WNL.33.11.1444","article-title":"Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)","volume":"33","author":"Kurtzke","year":"1983","journal-title":"Neurology"},{"key":"10.1016\/j.nicl.2018.07.012_bb0130","series-title":"Handbook of Clinical Neurology","first-page":"15","article-title":"Pathology of multiple sclerosis and related inflammatory demyelinating diseases","author":"Kutzelnigg","year":"2014"},{"key":"10.1016\/j.nicl.2018.07.012_bb0135","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1093\/brain\/awh641","article-title":"Cortical demyelination and diffuse white matter injury in multiple sclerosis","volume":"128","author":"Kutzelnigg","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0140","doi-asserted-by":"crossref","first-page":"3376","DOI":"10.1002\/hbm.22158","article-title":"Diffusion tensor imaging based network analysis detects alterations of neuroconnectivity in patients with clinically early relapsing-remitting multiple sclerosis","volume":"34","author":"Li","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.nicl.2018.07.012_bb0145","article-title":"Functional brain network alterations in clinically isolated syndrome and multiple sclerosis: a graph-based connectome study","author":"Liu","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.nicl.2018.07.012_bb0150","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jamaneurol.2014.895","article-title":"Magnetic resonance spectroscopy markers of disease progression in multiple sclerosis","volume":"71","author":"Llufriu","year":"2014","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0155","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1177\/1352458513503722","article-title":"Cognitive functions in multiple sclerosis: impact of gray matter integrity","volume":"20","author":"Llufriu","year":"2014","journal-title":"Mult. Scler."},{"key":"10.1016\/j.nicl.2018.07.012_bb0160","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.nicl.2016.11.026","article-title":"Structural networks involved in attention and executive functions in multiple sclerosis","volume":"13","author":"Llufriu","year":"2017","journal-title":"NeuroImage Clin."},{"key":"10.1016\/j.nicl.2018.07.012_bb0165","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137064","article-title":"Improved framework for Tractography reconstruction of the optic radiation","volume":"10","author":"Mart\u00ednez-Heras","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.nicl.2018.07.012_bb0170","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1001\/archneur.63.4.533","article-title":"Correlation of global N-acetyl aspartate with cognitive impairment in multiple sclerosis","volume":"63","author":"Mathiesen","year":"2006","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0177727","article-title":"The clinico-radiological paradox of cognitive function and MRI burden of white matter lesions in people with multiple sclerosis: a systematic review and meta-analysis","volume":"12","author":"Mollison","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.nicl.2018.07.012_bb0180","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.neuroimage.2016.08.031","article-title":"Functional segregation and integration within fronto-parietal networks","volume":"146","author":"Parlatini","year":"2016","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0185","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/ana.22366","article-title":"Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria","volume":"69","author":"Polman","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0190","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/mrm.1910300604","article-title":"Estimation of metabolite concentrations from localized in vivo proton NMR spectra","volume":"30","author":"Provencher","year":"1993","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.nicl.2018.07.012_bb0195","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1056\/NEJMra1401483","article-title":"Multiple Sclerosis","volume":"378","author":"Reich","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.nicl.2018.07.012_bb0200","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s00429-014-0896-4","article-title":"Impaired functional integration in multiple sclerosis: a graph theory study","volume":"221","author":"Rocca","year":"2016","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.nicl.2018.07.012_bb0205","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: uses and interpretations","volume":"52","author":"Rubinov","year":"2010","journal-title":"NeuroImage"},{"issue":"Pt 3","key":"10.1016\/j.nicl.2018.07.012_bb0210","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/brain\/122.3.513","article-title":"Absolute quantification of brain metabolites by proton magnetic resonance spectroscopy in normal-appearing white matter of multiple sclerosis patients","volume":"122","author":"Sarchielli","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.nicl.2018.07.012_bb0215","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3389\/fneur.2015.00082","article-title":"Network collapse and cognitive impairment in multiple sclerosis","volume":"6","author":"Schoonheim","year":"2015","journal-title":"Front. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0220","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1007\/s00415-006-0145-8","article-title":"Cognition in the early stage of multiple sclerosis","volume":"253","author":"Schulz","year":"2006","journal-title":"J. Neurol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0225","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1191\/1352458506ms1258oa","article-title":"Cognitive impairment in patients with multiple sclerosis using the Brief Repeatable Battery-Neuropsychology test","volume":"12","author":"Sepulcre","year":"2006","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.nicl.2018.07.012_bb0230","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1093\/cercor\/bhr039","article-title":"Diffusion tensor tractography reveals disrupted topological efficiency in white matter structural networks in multiple sclerosis","volume":"21","author":"Shu","year":"2011","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.nicl.2018.07.012_bb0235","doi-asserted-by":"crossref","first-page":"29383","DOI":"10.1038\/srep29383","article-title":"Disrupted topological organization of structural and functional brain connectomes in clinically isolated syndrome and multiple sclerosis","volume":"6","author":"Shu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.nicl.2018.07.012_bb0240","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1016\/j.neuroimage.2012.06.005","article-title":"Anatomically-constrained tractography: improved diffusion MRI streamlines tractography through effective use of anatomical information","volume":"62","author":"Smith","year":"2012","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0245","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.neuroimage.2005.01.028","article-title":"Demyelination increases radial diffusivity in corpus callosum of mouse brain","volume":"26","author":"Song","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0250","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.conb.2012.11.015","article-title":"Network attributes for segregation and integration in the human brain","volume":"23","author":"Sporns","year":"2013","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0255","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.neuroimage.2005.10.048","article-title":"TE-averaged two-dimensional proton spectroscopic imaging of glutamate at 3 T","volume":"30","author":"Srinivasan","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.nicl.2018.07.012_bb0260","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3389\/fphys.2013.00169","article-title":"Mitochondrial dysfunction and neurodegeneration in multiple sclerosis","volume":"4","author":"Su","year":"2013","journal-title":"Front. Physiol."},{"key":"10.1016\/j.nicl.2018.07.012_bb0265","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1002\/mrm.26059","article-title":"Diffusion MRI noise mapping using random matrix theory","volume":"76","author":"Veraart","year":"2016","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.nicl.2018.07.012_bb0270","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1002\/mrm.21965","article-title":"About \u201caxial\u201d and \u201cradial\u201d diffusivities","volume":"61","author":"Wheeler-Kingshott","year":"2009","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.nicl.2018.07.012_bb0275","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"}],"container-title":["NeuroImage: Clinical"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218302249?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213158218302249?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:16:01Z","timestamp":1761970561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213158218302249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":55,"alternative-id":["S2213158218302249"],"URL":"https:\/\/doi.org\/10.1016\/j.nicl.2018.07.012","relation":{},"ISSN":["2213-1582"],"issn-type":[{"value":"2213-1582","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Magnetic resonance markers of tissue damage related to connectivity disruption in multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Clinical","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nicl.2018.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}