{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:40:00Z","timestamp":1790775600143,"version":"4.1.0"},"reference-count":129,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nitric Oxide"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.niox.2014.02.006","type":"journal-article","created":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T12:00:46Z","timestamp":1393416046000},"page":"62-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":151,"special_numbering":"C","title":["Hydrogen sulfide and the liver"],"prefix":"10.1016","volume":"41","author":[{"given":"Sarathi","family":"Mani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.niox.2014.02.006_b0005","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.niox.2014.02.006_b0010","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/(SICI)1097-010X(19981015)282:3<310::AID-JEZ4>3.0.CO;2-P","article-title":"Sulfur reduction by human erythrocytes","volume":"282","author":"Searcy","year":"1998","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.niox.2014.02.006_b0015","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two\u2019s company, three\u2019s a crowd: can H2S be the third endogenous gaseous transmitter?","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.niox.2014.02.006_b0020","doi-asserted-by":"crossref","DOI":"10.1152\/ajpregu.90566.2008","article-title":"Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values","volume":"295","author":"Furne","year":"2008","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0025","doi-asserted-by":"crossref","first-page":"17907","DOI":"10.1073\/pnas.0709010104","article-title":"A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide","volume":"104","author":"Lefer","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2014.02.006_b0030","doi-asserted-by":"crossref","first-page":"12679","DOI":"10.1073\/pnas.1308487110","article-title":"Oxygen-sensitive mitochondrial accumulation of cystathionine beta-synthase mediated by Lon protease","volume":"110","author":"Teng","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2014.02.006_b0035","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nrd2425","article-title":"Hydrogen sulphide and its therapeutic potential","volume":"6","author":"Szabo","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.niox.2014.02.006_b0040","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1042\/CS20110267","article-title":"Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools","volume":"121","author":"Whiteman","year":"2011","journal-title":"Clin. Sci. (Lond)"},{"key":"10.1016\/j.niox.2014.02.006_b0045","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.niox.2014.02.006_b0050","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1161\/CIRCULATIONAHA.113.002208","article-title":"Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis","volume":"127","author":"Mani","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.niox.2014.02.006_b0055","article-title":"Hydrogen Sulfide and the Pathogenesis of Atherosclerosis","author":"Mani","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0060","doi-asserted-by":"crossref","first-page":"e29592","DOI":"10.1371\/journal.pone.0029592","article-title":"Increased renal methylglyoxal formation with down-regulation of PGC-1alpha-FBPase pathway in cystathionine gamma-lyase knockout mice","volume":"6","author":"Untereiner","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.niox.2014.02.006_b0065","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1042\/BJ20040243","article-title":"Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression","volume":"381","author":"Ishii","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.niox.2014.02.006_b0070","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ejphar.2009.01.041","article-title":"Characterisation of cystathionine gamma-lyase\/hydrogen sulphide pathway in ischaemia\/reperfusion injury of the mouse kidney: an in vivo study","volume":"606","author":"Tripatara","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0075","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/labinvest.2008.109","article-title":"Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats","volume":"89","author":"Wu","year":"2009","journal-title":"Lab. Invest."},{"key":"10.1016\/j.niox.2014.02.006_b0080","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1089\/ars.2009.2918","article-title":"Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells","volume":"12","author":"Chang","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0085","doi-asserted-by":"crossref","first-page":"6008","DOI":"10.1093\/emboj\/20.21.6008","article-title":"The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener","volume":"20","author":"Zhao","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.niox.2014.02.006_b0090","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1096\/fj.04-2279fje","article-title":"Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3","volume":"18","author":"Yang","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.niox.2014.02.006_b0095","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.pupt.2006.11.002","article-title":"Effect of theophylline on endogenous hydrogen sulfide production in patients with COPD","volume":"21","author":"Chen","year":"2008","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.niox.2014.02.006_b0100","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1113\/expphysiol.2011.057448","article-title":"Hydrogen sulfide and asthma","volume":"96","author":"Wang","year":"2011","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0105","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1042\/bj2690335","article-title":"Sequence of cDNA for rat cystathionine gamma-lyase and comparison of deduced amino acid sequence with related Escherichia coli enzymes","volume":"269","author":"Erickson","year":"1990","journal-title":"Biochem. J."},{"key":"10.1016\/j.niox.2014.02.006_b0110","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","article-title":"The possible role of hydrogen sulfide as an endogenous neuromodulator","volume":"16","author":"Abe","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.niox.2014.02.006_b0115","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1042\/bj2060267","article-title":"Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat","volume":"206","author":"Stipanuk","year":"1982","journal-title":"Biochem. J."},{"key":"10.1016\/j.niox.2014.02.006_b0120","doi-asserted-by":"crossref","first-page":"31504","DOI":"10.1074\/jbc.M213036200","article-title":"Altered gene expression in liver from a murine model of hyperhomocysteinemia","volume":"278","author":"Robert","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.niox.2014.02.006_b0125","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1172\/JCI7712","article-title":"Detoxification of hydrogen sulfide and methanethiol in the cecal mucosa","volume":"104","author":"Levitt","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.niox.2014.02.006_b0130","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1159\/000108967","article-title":"Hydrogen sulfide, nitric oxide and a molecular mass 66 u substance in the exhaled breath of chronic pancreatitis patients","volume":"7","author":"Morselli-Labate","year":"2007","journal-title":"Pancreatology"},{"key":"10.1016\/j.niox.2014.02.006_b0135","article-title":"Differentiation of mouth versus gut as site of origin of odoriferous breath gases after garlic ingestion","volume":"276","author":"Suarez","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0140","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1439-0396.2007.00752.x","article-title":"Liver lipid metabolism","volume":"92","author":"Nguyen","year":"2008","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.niox.2014.02.006_b0145","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1146\/annurev.nu.16.070196.002515","article-title":"Regulation of hepatic de novo lipogenesis in humans","volume":"16","author":"Hellerstein","year":"1996","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.niox.2014.02.006_b0150","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1161\/ATVBAHA.111.241455","article-title":"Intrahepatic role of exchangeable apolipoproteins in lipoprotein assembly and secretion","volume":"32","author":"Sundaram","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.niox.2014.02.006_b0155","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/MOL.0b013e32833b7782","article-title":"Recent insights into fatty liver, metabolic dyslipidaemia and their links to insulin resistance","volume":"21","author":"Savage","year":"2010","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.niox.2014.02.006_b0160","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1172\/JCI23621","article-title":"Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease","volume":"115","author":"Donnelly","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.niox.2014.02.006_b0165","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1007\/s00018-006-6600-y","article-title":"Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise","volume":"63","author":"Lavoie","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.niox.2014.02.006_b0170","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1301\/nr.2007.jun.S57-S63","article-title":"Obesity and nonalcoholic fatty liver disease","volume":"65","author":"Angulo","year":"2007","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.niox.2014.02.006_b0175","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.numecd.2007.01.007","article-title":"Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: an open question","volume":"17","author":"Loria","year":"2007","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"10.1016\/j.niox.2014.02.006_b0180","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1073\/pnas.92.5.1585","article-title":"Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia","volume":"92","author":"Watanabe","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2014.02.006_b0185","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1053\/j.gastro.2005.02.034","article-title":"Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver","volume":"128","author":"Robert","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.niox.2014.02.006_b0190","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jhep.2006.07.028","article-title":"Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice","volume":"46","author":"Hamelet","year":"2007","journal-title":"J. Hepatol."},{"key":"10.1016\/j.niox.2014.02.006_b0195","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.freeradbiomed.2011.01.038","article-title":"A critical life-supporting role for cystathionine gamma-lyase in the absence of dietary cysteine supply","volume":"50","author":"Mani","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.niox.2014.02.006_b0200","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1139\/cjpp-2013-0106","article-title":"High-fat diet stimulates hepatic cystathionine beta-synthase and cystathionine gamma-lyase expression","volume":"91","author":"Hwang","year":"2013","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0205","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/SHK.0b013e3182252ee7","article-title":"The liver as a central regulator of hydrogen sulfide","volume":"36","author":"Norris","year":"2011","journal-title":"Shock"},{"key":"10.1016\/j.niox.2014.02.006_b0210","doi-asserted-by":"crossref","first-page":"52961","DOI":"10.1074\/jbc.M406820200","article-title":"Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia","volume":"279","author":"Namekata","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.niox.2014.02.006_b0215","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1096\/fj.07-105353","article-title":"Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL\/6J mice","volume":"22","author":"Zhou","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.niox.2014.02.006_b0220","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.atherosclerosis.2012.08.036","article-title":"Relationship between hydrogen sulfide levels and HDL-cholesterol, adiponectin, and potassium levels in the blood of healthy subjects","volume":"225","author":"Jain","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.niox.2014.02.006_b0225","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.phrs.2010.10.011","article-title":"Differential effects of statins on endogenous H2S formation in perivascular adipose tissue","volume":"63","author":"Wojcicka","year":"2011","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.niox.2014.02.006_b0230","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1080\/10408390802145344","article-title":"Garlic: nature\u2019s protection against physiological threats","volume":"49","author":"Butt","year":"2009","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.niox.2014.02.006_b0235","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1073\/pnas.0705710104","article-title":"Hydrogen sulfide mediates the vasoactivity of garlic","volume":"104","author":"Benavides","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2014.02.006_b0240","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.fct.2011.11.030","article-title":"Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-alpha, and CYP2E1","volume":"50","author":"Zeng","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.niox.2014.02.006_b0245","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.clinbiochem.2009.05.018","article-title":"Hepatic insulin resistance, metabolic syndrome and cardiovascular disease","volume":"42","author":"Meshkani","year":"2009","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.niox.2014.02.006_b0250","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1002\/hep.20920","article-title":"Insulin resistance. a metabolic pathway to chronic liver disease","volume":"42","author":"Bugianesi","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.niox.2014.02.006_b0255","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.bbrc.2005.06.021","article-title":"Streptozotocin-induced diabetes in the rat is associated with enhanced tissue hydrogen sulfide biosynthesis","volume":"333","author":"Yusuf","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.niox.2014.02.006_b0260","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S1734-1140(13)71053-3","article-title":"Metformin raises hydrogen sulfide tissue concentrations in various mouse organs","volume":"65","author":"Wilinski","year":"2013","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.niox.2014.02.006_b0265","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1210\/en.2012-1658","article-title":"Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes","volume":"154","author":"Zhang","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.niox.2014.02.006_b0270","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1089\/ars.2011.4451","article-title":"Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications","volume":"17","author":"Szabo","year":"2012","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0275","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1161\/01.HYP.34.6.1247","article-title":"Effects of superoxide on signaling pathways in smooth muscle cells from rats","volume":"34","author":"Wu","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.niox.2014.02.006_b0280","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1006\/bbrc.1999.0762","article-title":"Superoxide anion-induced formation of inositol phosphates involves tyrosine kinase activation in smooth muscle cells from rat mesenteric artery","volume":"259","author":"Wu","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.niox.2014.02.006_b0285","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1172\/JCI200422422","article-title":"Molecular mediators of hepatic steatosis and liver injury","volume":"114","author":"Browning","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.niox.2014.02.006_b0290","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.numecd.2008.12.015","article-title":"Hepatic lipid metabolism and non-alcoholic fatty liver disease","volume":"19","author":"Tessari","year":"2009","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"10.1016\/j.niox.2014.02.006_b0295","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1139\/cjpp-2012-0293","article-title":"H(2)S signaling in redox regulation of cellular functions","volume":"91","author":"Ju","year":"2013","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0300","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.freeradbiomed.2008.11.018","article-title":"Supression of hemin-mediated oxidation of low-density lipoprotein and subsequent endothelial reactions by hydrogen sulfide (H(2)S)","volume":"46","author":"Jeney","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.niox.2014.02.006_b0305","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1080\/10715760701263265","article-title":"Hydrogen sulphide: a novel physiological inhibitor of LDL atherogenic modification by HOCl","volume":"41","author":"Laggner","year":"2007","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.niox.2014.02.006_b0310","doi-asserted-by":"crossref","first-page":"e74366","DOI":"10.1371\/journal.pone.0074366","article-title":"H2S inhibits hyperglycemia-Induced intrarenal renin-angiotensin system activation via attenuation of reactive oxygen species generation","volume":"8","author":"Xue","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.niox.2014.02.006_b0315","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.neuint.2012.01.015","article-title":"Glutamate oxidative injury to RGC-5 cells in culture is necrostatin sensitive and blunted by a hydrogen sulfide (H2S)-releasing derivative of aspirin (ACS14)","volume":"60","author":"Osborne","year":"2012","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.niox.2014.02.006_b0320","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1089\/ars.2005.7.1040","article-title":"The molecular basis for oxidative stress-induced insulin resistance","volume":"7","author":"Evans","year":"2005","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0325","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/00042871-200412000-00022","article-title":"Oxidative stress in nonalcoholic fatty liver disease: pathogenesis and antioxidant therapies","volume":"52","author":"Gawrieh","year":"2004","journal-title":"J. Investig. Med."},{"key":"10.1016\/j.niox.2014.02.006_b0330","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0098-2997(00)00004-2","article-title":"Pathogenesis of liver fibrosis: role of oxidative stress","volume":"21","author":"Poli","year":"2000","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.niox.2014.02.006_b0335","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.00377.2008","article-title":"Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling","volume":"295","author":"Jha","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0340","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1586\/ecp.10.131","article-title":"Hydrogen sulfide in cell survival: a double-edged sword","volume":"4","author":"Yang","year":"2011","journal-title":"Expert Rev. Clin. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0345","doi-asserted-by":"crossref","first-page":"e25943","DOI":"10.1371\/journal.pone.0025943","article-title":"Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats","volume":"6","author":"Tan","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.niox.2014.02.006_b0350","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1089\/ars.2012.4645","article-title":"Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2","volume":"18","author":"Yang","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0355","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1089\/ars.2012.4944","article-title":"The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613","volume":"19","author":"Hourihan","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0360","doi-asserted-by":"crossref","first-page":"26358","DOI":"10.1074\/jbc.M110.147439","article-title":"Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury","volume":"285","author":"Ishii","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.niox.2014.02.006_b0365","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.bbrc.2013.02.131","article-title":"Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase\/hydrogen sulfide pathway","volume":"433","author":"Modis","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.niox.2014.02.006_b0370","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0098-2997(03)00023-2","article-title":"4-hydroxynonenal as a bioactive marker of pathophysiological processes","volume":"24","author":"Zarkovic","year":"2003","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.niox.2014.02.006_b0375","doi-asserted-by":"crossref","first-page":"9895","DOI":"10.1016\/S0021-9258(18)48018-0","article-title":"Protein damage and degradation by oxygen radicals. I. general aspects","volume":"262","author":"Davies","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.niox.2014.02.006_b0380","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1172\/JCI114934","article-title":"Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload","volume":"86","author":"Houglum","year":"1990","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.niox.2014.02.006_b0385","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.lfs.2010.10.004","article-title":"Curative effects of hydrogen sulfide against acetaminophen-induced hepatotoxicity in mice","volume":"87","author":"Morsy","year":"2010","journal-title":"Life Sci."},{"key":"10.1016\/j.niox.2014.02.006_b0390","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1743-7075-8-53","article-title":"Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats","volume":"8","author":"Padiya","year":"2011","journal-title":"Nutr. Metab. (Lond)"},{"key":"10.1016\/j.niox.2014.02.006_b0395","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1080\/03602530600959607","article-title":"Molecular mechanisms of hydrogen sulfide toxicity","volume":"38","author":"Truong","year":"2006","journal-title":"Drug Metab. Rev."},{"key":"10.1016\/j.niox.2014.02.006_b0400","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00109-008-0407-2","article-title":"Homocysteine enhances cell proliferation in hepatic myofibroblastic stellate cells","volume":"87","author":"Zou","year":"2009","journal-title":"J. Mol. Med. (Berl)"},{"key":"10.1016\/j.niox.2014.02.006_b0405","article-title":"Cystathionine gamma-lyase deficiency protects mice from galactosamine\/lipopolysaccharide-induced acute liver failure","author":"Shirozu","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0410","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/(SICI)1099-0461(1999)13:3\/4<135::AID-JBT3>3.0.CO;2-Z","article-title":"Galactosamine decreases nitric oxide formation in cultured rat hepatocytes: lack of involvement in cytotoxicity","volume":"13","author":"McMillan","year":"1999","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.niox.2014.02.006_b0415","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2486\/indhealth.33.199","article-title":"Elevation of cystathionine gamma-lyase activity in the serum of rats treated with a single dose of carbon tetrachloride","volume":"33","author":"Taguchi","year":"1995","journal-title":"Ind. Health"},{"key":"10.1016\/j.niox.2014.02.006_b0420","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1126\/science.283.5407.1488","article-title":"Oxidative phosphorylation at the fin de siecle","volume":"283","author":"Saraste","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.niox.2014.02.006_b0425","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1113\/jphysiol.2003.049478","article-title":"Mitochondrial formation of reactive oxygen species","volume":"552","author":"Turrens","year":"2003","journal-title":"J. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0430","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/35036035","article-title":"The versatility and universality of calcium signalling","volume":"1","author":"Berridge","year":"2000","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.niox.2014.02.006_b0435","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1161\/ATVBAHA.107.151167","article-title":"Nitric oxide and mitochondrial signaling: from physiology to pathophysiology","volume":"27","author":"Erusalimsky","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.niox.2014.02.006_b0440","doi-asserted-by":"crossref","DOI":"10.1152\/ajpheart.00339.2009","article-title":"Hydrogen sulfide protects cardiomyocytes from hypoxia\/reoxygenation-induced apoptosis by preventing GSK-3beta-dependent opening of mPTP","volume":"298","author":"Yao","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0445","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1073\/pnas.1115634109","article-title":"Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production","volume":"109","author":"Fu","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2014.02.006_b0450","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1126\/science.1108581","article-title":"H2S induces a suspended animation-like state in mice","volume":"308","author":"Blackstone","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.niox.2014.02.006_b0455","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.bbabio.2010.04.004","article-title":"Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes","volume":"1797","author":"Lagoutte","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.niox.2014.02.006_b0460","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/sj.cr.7290168","article-title":"Metabolic integration during the evolutionary origin of mitochondria","volume":"13","author":"Searcy","year":"2003","journal-title":"Cell Res."},{"key":"10.1016\/j.niox.2014.02.006_b0465","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/lt.22157","article-title":"Reactive oxygen species mediate human hepatocyte injury during hypoxia\/reoxygenation","volume":"16","author":"Bhogal","year":"2010","journal-title":"Liver Transplant."},{"key":"10.1016\/j.niox.2014.02.006_b0470","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/shk.0b013e3180485acd","article-title":"Hypoxia activates c-Jun N-terminal kinase via Rac1-dependent reactive oxygen species production in hepatocytes","volume":"28","author":"Mollen","year":"2007","journal-title":"Shock"},{"key":"10.1016\/j.niox.2014.02.006_b0475","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1096\/fj.12-216507","article-title":"Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics","volume":"27","author":"Modis","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.niox.2014.02.006_b0480","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S1473-3099(05)70216-4","article-title":"Global epidemiology of hepatitis C virus infection","volume":"5","author":"Shepard","year":"2005","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.niox.2014.02.006_b0485","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1016\/S0140-6736(07)60941-6","article-title":"Hazardous alcohol drinking and premature mortality in Russia: a population based case-control study","volume":"369","author":"Leon","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.niox.2014.02.006_b0490","doi-asserted-by":"crossref","first-page":"S99","DOI":"10.1002\/hep.20973","article-title":"Nonalcoholic fatty liver disease: from steatosis to cirrhosis","volume":"43","author":"Farrell","year":"2006","journal-title":"Hepatology"},{"issue":"Suppl 1","key":"10.1016\/j.niox.2014.02.006_b0495","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1016\/S0168-8278(02)00429-4","article-title":"Liver fibrosis \u2013 from bench to bedside","volume":"38","author":"Friedman","year":"2003","journal-title":"J. Hepatol."},{"key":"10.1016\/j.niox.2014.02.006_b0500","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jhep.2007.01.025","article-title":"Worldwide mortality from cirrhosis: an update to 2002","volume":"46","author":"Bosetti","year":"2007","journal-title":"J. Hepatol."},{"key":"10.1016\/j.niox.2014.02.006_b0505","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hep.20817","article-title":"The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis","volume":"42","author":"Fiorucci","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.niox.2014.02.006_b0510","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1586\/ecp.10.129","article-title":"Therapeutic applications of organosulfur compounds as novel hydrogen sulfide donors and\/or mediators","volume":"4","author":"Gu","year":"2011","journal-title":"Expert Rev. Clin. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0515","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.atherosclerosis.2006.08.021","article-title":"Non-alcoholic fatty liver disease and increased risk of cardiovascular disease","volume":"191","author":"Targher","year":"2007","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.niox.2014.02.006_b0520","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0140-6736(05)66378-7","article-title":"The metabolic syndrome","volume":"365","author":"Eckel","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.niox.2014.02.006_b0525","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-56553-3_7","article-title":"Cooperation of liver cells in health and disease","volume":"161","author":"Kmiec","year":"2001","journal-title":"Adv. Anat. Embryol. Cell Biol."},{"key":"10.1016\/j.niox.2014.02.006_b0530","first-page":"911","article-title":"Preventive effect of exogenous hydrogen sulfide on hepatic fibrosis in rats","volume":"37","author":"Shen","year":"2012","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban"},{"key":"10.1016\/j.niox.2014.02.006_b0535","first-page":"644","article-title":"Decreased expression of p38 MAPK mediates protective effects of hydrogen sulfide on hepatic fibrosis","volume":"17","author":"Fan","year":"2013","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.niox.2014.02.006_b0540","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0168-8278(05)80118-7","article-title":"Blockade of ATP-sensitive K+ channels by glibenclamide reduces portal pressure and hyperkinetic circulation in portal hypertensive rats","volume":"16","author":"Moreau","year":"1992","journal-title":"J. Hepatol."},{"key":"10.1016\/j.niox.2014.02.006_b0545","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0273-2300(03)00007-2","article-title":"Utilizing data from multiple studies (meta-analysis) to determine effective dose\u2013duration levels. Example: rats and mice exposed to hydrogen sulfide","volume":"37","author":"Brown","year":"2003","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0550","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1159\/000072064","article-title":"Protection of the liver by ischemic preconditioning: a review of mechanisms and clinical applications","volume":"20","author":"Koti","year":"2003","journal-title":"Dig. Surg."},{"key":"10.1016\/j.niox.2014.02.006_b0555","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1002\/lt.21810","article-title":"Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats","volume":"15","author":"Kang","year":"2009","journal-title":"Liver Transplant."},{"key":"10.1016\/j.niox.2014.02.006_b0560","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.pa.32.040192.000545","article-title":"Toxicology of hydrogen sulfide","volume":"32","author":"Reiffenstein","year":"1992","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"518","key":"10.1016\/j.niox.2014.02.006_b0565","first-page":"e5","article-title":"Acute hydrogen sulfide toxicity due to sewer gas exposure","volume":"26","author":"Yalamanchili","year":"2008","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.niox.2014.02.006_b0570","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/10408448409029321","article-title":"A critical review of the literature on hydrogen sulfide toxicity","volume":"13","author":"Beauchamp","year":"1984","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.niox.2014.02.006_b0575","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jat.2550130605","article-title":"High-performance liquid chromatography detection of sulfide in tissues from sulfide-treated mice","volume":"13","author":"Mitchell","year":"1993","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.niox.2014.02.006_b0580","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","article-title":"Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.niox.2014.02.006_b0585","doi-asserted-by":"crossref","DOI":"10.1152\/ajpgi.00395.2012","article-title":"Hydrogen sulfide modulates sinusoidal constriction and contributes to hepatic microcirculatory dysfunction during endotoxemia","volume":"304","author":"Norris","year":"2013","journal-title":"Am. J. Physiol. Gastrointest Liver Physiol."},{"key":"10.1016\/j.niox.2014.02.006_b0590","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/00024382-200211000-00005","article-title":"Potentiated hepatic microcirculatory response to endothelin-1 during polymicrobial sepsis","volume":"18","author":"Baveja","year":"2002","journal-title":"Shock"},{"key":"10.1016\/j.niox.2014.02.006_b0595","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.mvr.2005.03.003","article-title":"Quantification of hepatic microcirculation heterogeneity of perfusion: effects of endothelin-1","volume":"69","author":"Kamoun","year":"2005","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.niox.2014.02.006_b0600","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1124\/mol.105.017467","article-title":"Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells","volume":"68","author":"Tang","year":"2005","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.niox.2014.02.006_b0605","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/toxsci\/65.1.18","article-title":"Cytochrome oxidase inhibition induced by acute hydrogen sulfide inhalation: correlation with tissue sulfide concentrations in the rat brain, liver, lung, and nasal epithelium","volume":"65","author":"Dorman","year":"2002","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.niox.2014.02.006_b0610","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1177\/1091581810384882","article-title":"Hydrogen sulfide: advances in understanding human toxicity","volume":"29","author":"Guidotti","year":"2010","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.niox.2014.02.006_b0615","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1042\/bj2240591","article-title":"Interactions of sulphide and other ligands with cytochrome c oxidase. An electron-paramagnetic-resonance study","volume":"224","author":"Hill","year":"1984","journal-title":"Biochem. J."},{"key":"10.1016\/j.niox.2014.02.006_b0620","doi-asserted-by":"crossref","first-page":"a011437","DOI":"10.1101\/cshperspect.a011437","article-title":"Altered sulfide (H(2)S) metabolism in ethylmalonic encephalopathy","volume":"5","author":"Tiranti","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.niox.2014.02.006_b0625","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1089\/ars.2010.3520","article-title":"Chronic exposure to sulfide causes accelerated degradation of cytochrome c oxidase in ethylmalonic encephalopathy","volume":"15","author":"Di Meo","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.niox.2014.02.006_b0630","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.tox.2004.05.020","article-title":"H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation","volume":"203","author":"Eghbal","year":"2004","journal-title":"Toxicology"},{"key":"10.1016\/j.niox.2014.02.006_b0635","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1248\/bpb.b13-00502","article-title":"Assessment of effects of chronic hydrogen sulfide poisoning on cytochrome P450 isoforms activity of rats by cocktail approach","volume":"36","author":"Wang","year":"2013","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.niox.2014.02.006_b0640","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/toxsci\/kfj031","article-title":"Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1","volume":"89","author":"Lu","year":"2006","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.niox.2014.02.006_b0645","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1111\/j.1745-7254.2007.00629.x","article-title":"Hydrogen sulfide: third gaseous transmitter, but with great pharmacological potential","volume":"28","author":"Chen","year":"2007","journal-title":"Acta Pharmacol. Sin."}],"container-title":["Nitric Oxide"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860314000093?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860314000093?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T20:06:38Z","timestamp":1648411598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089860314000093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":129,"alternative-id":["S1089860314000093"],"URL":"https:\/\/doi.org\/10.1016\/j.niox.2014.02.006","relation":{},"ISSN":["1089-8603"],"issn-type":[{"value":"1089-8603","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrogen sulfide and the liver","name":"articletitle","label":"Article Title"},{"value":"Nitric Oxide","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.niox.2014.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}