{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:30:25Z","timestamp":1790523025789,"version":"4.1.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004189","name":"Max-Planck-Gesellschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nitric Oxide"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.niox.2020.12.002","type":"journal-article","created":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T23:35:36Z","timestamp":1608161736000},"page":"31-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development"],"prefix":"10.1016","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1833-9905","authenticated-orcid":false,"given":"Ettore","family":"Lignelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5352-6773","authenticated-orcid":false,"given":"Francesco","family":"Palumbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1746-2274","authenticated-orcid":false,"given":"Selahattin G\u00f6rkem","family":"Bayindir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4476-5748","authenticated-orcid":false,"given":"Noriyuki","family":"Nagahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1370-9783","authenticated-orcid":false,"given":"Istv\u00e1n","family":"Vad\u00e1sz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6343-0911","authenticated-orcid":false,"given":"Susanne","family":"Herold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1946-0894","authenticated-orcid":false,"given":"Werner","family":"Seeger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0833-9749","authenticated-orcid":false,"given":"Rory E.","family":"Morty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00441-016-2545-0","article-title":"Development of the lung","volume":"367","author":"Schittny","year":"2017","journal-title":"Cell Tissue Res."},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1056\/NEJM196702162760701","article-title":"Pulmonary disease following respirator therapy of hyaline-membrane disease","volume":"276","author":"Northway","year":"1967","journal-title":"Bronchopulmonary dysplasia, N Engl J Med"},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib3","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1053\/j.semperi.2006.05.004","article-title":"Pathology of bronchopulmonary dysplasia","volume":"30","author":"Coalson","year":"2006","journal-title":"Semin. Perinatol."},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib4","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.clp.2015.08.010","article-title":"Pulmonary hypertension and vascular abnormalities in bronchopulmonary dysplasia","volume":"42","author":"Mourani","year":"2015","journal-title":"Clin. Perinatol."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib5","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1513\/AnnalsATS.201305-124OC","article-title":"Histologic evidence of intrapulmonary anastomoses by three-dimensional reconstruction in severe bronchopulmonary dysplasia","volume":"10","author":"Galambos","year":"2013","journal-title":"Ann Am Thorac Soc"},{"issue":"2","key":"10.1016\/j.niox.2020.12.002_bib6","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2350\/11-09-1099-CR.1","article-title":"Pulmonary venous stenosis in a premature infant with bronchopulmonary dysplasia: clinical and autopsy findings of these newly associated entities","volume":"15","author":"Smith","year":"2012","journal-title":"Pediatr. Dev. Pathol."},{"key":"10.1016\/j.niox.2020.12.002_bib7","doi-asserted-by":"crossref","DOI":"10.2350\/16-01-1759-CR.1","article-title":"Florid intussusceptive-like microvascular dysangiogenesis in a preterm Lung","author":"De Paepe","year":"2016","journal-title":"Pediatr. Dev. Pathol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib8","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/bdra.23241","article-title":"Pulmonary hypertension in bronchopulmonary dysplasia","volume":"100","author":"Ambalavanan","year":"2014","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"issue":"6","key":"10.1016\/j.niox.2020.12.002_bib9","doi-asserted-by":"crossref","first-page":"L832","DOI":"10.1152\/ajplung.00369.2019","article-title":"Recent advances in our understanding of the mechanisms of lung alveolarization and bronchopulmonary dysplasia","volume":"317","author":"Lignelli","year":"2019","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.niox.2020.12.002_bib10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.niox.2020.01.012","article-title":"Neonatal comorbidities and gasotransmitters","volume":"97","author":"Gentle","year":"2020","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.niox.2020.12.002_bib11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.niox.2019.12.002","article-title":"The role of gasotransmitters in neonatal physiology","volume":"95","author":"Liu","year":"2020","journal-title":"Nitric Oxide"},{"issue":"4 Pt 1","key":"10.1016\/j.niox.2020.12.002_bib12","first-page":"L589","article-title":"Constitutive endothelial nitric oxide synthase gene expression is regulated during lung development","volume":"268","author":"Kawai","year":"1995","journal-title":"Am. J. Physiol."},{"issue":"2","key":"10.1016\/j.niox.2020.12.002_bib13","first-page":"L383","article-title":"Nitric oxide synthase isoform expression in the developing lung epithelium","volume":"276","author":"Sherman","year":"1999","journal-title":"Am. J. Physiol."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib14","doi-asserted-by":"crossref","first-page":"L202","DOI":"10.1152\/ajplung.2000.278.1.L202","article-title":"Developmental changes in endothelial nitric oxide synthase expression and activity in ovine fetal lung","volume":"278","author":"Parker","year":"2000","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"6","key":"10.1016\/j.niox.2020.12.002_bib15","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0022-3476(05)83175-0","article-title":"Acute effects of inhaled nitric oxide in children with severe hypoxemic respiratory failure","volume":"124","author":"Abman","year":"1994","journal-title":"J. Pediatr."},{"key":"10.1016\/j.niox.2020.12.002_bib16","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.niox.2019.11.001","article-title":"Past, current and future perspectives of the use of inhaled NO as a primary therapeutic for the newborn","volume":"94","author":"Philips","year":"2020","journal-title":"Nitric Oxide"},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib17","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1165\/rcmb.2017-0114TR","article-title":"Hydrogen sulfide: a novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses","volume":"57","author":"Bazhanov","year":"2017","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.niox.2020.12.002_bib18","doi-asserted-by":"crossref","first-page":"172983","DOI":"10.1016\/j.ejphar.2020.172983","article-title":"The effects of gasotransmitters on bronchopulmonary dysplasia","volume":"873","author":"Lin","year":"2020","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib19","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/00365514909069943","article-title":"Endogenous formation of carbon monoxide in man under normal and pathological conditions","volume":"1","author":"Sj\u00f6strand","year":"1949","journal-title":"Scand. J. Clin. Lab. Investig."},{"issue":"2","key":"10.1016\/j.niox.2020.12.002_bib20","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1073\/pnas.61.2.748","article-title":"The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase","volume":"61","author":"Tenhunen","year":"1968","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib21","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1165\/ajrcmb.15.1.8679227","article-title":"Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury","volume":"15","author":"Choi","year":"1996","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"13","key":"10.1016\/j.niox.2020.12.002_bib22","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1089\/ars.2013.5791","article-title":"Heme oxygenase in neonatal lung injury and repair","volume":"21","author":"Dennery","year":"2014","journal-title":"Antioxidants Redox Signal."},{"issue":"8","key":"10.1016\/j.niox.2020.12.002_bib23","doi-asserted-by":"crossref","first-page":"L775","DOI":"10.1152\/ajplung.00196.2011","article-title":"Vasculoprotective effects of heme oxygenase-1 in a murine model of hyperoxia-induced bronchopulmonary dysplasia","volume":"302","author":"Fernandez-Gonzalez","year":"2012","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"8","key":"10.1016\/j.niox.2020.12.002_bib24","doi-asserted-by":"crossref","first-page":"L749","DOI":"10.1152\/ajplung.00236.2013","article-title":"Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide","volume":"306","author":"Anyanwu","year":"2014","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.niox.2020.12.002_bib25","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.00214.2018","article-title":"The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanisms","author":"Dunigan","year":"2018","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib26","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1165\/rcmb.2015-0228OC","article-title":"Thioredoxin reductase inhibition attenuates neonatal hyperoxic lung injury and enhances nuclear factor E2-related factor 2 activation","volume":"55","author":"Li","year":"2016","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib27","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1089\/152308603768295249","article-title":"The gasotransmitter role of hydrogen sulfide","volume":"5","author":"Wang","year":"2003","journal-title":"Antioxidants Redox Signal."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib28","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s00441-016-2534-3","article-title":"Looking ahead: where to next for animal models of bronchopulmonary dysplasia?","volume":"367","author":"Nardiello","year":"2017","journal-title":"Cell Tissue Res."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib29","doi-asserted-by":"crossref","first-page":"L403","DOI":"10.1152\/ajplung.00327.2014","article-title":"Working with nitric oxide and hydrogen sulfide in biological systems","volume":"308","author":"Yuan","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"2","key":"10.1016\/j.niox.2020.12.002_bib30","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1089\/ars.2010.3781","article-title":"The quantitative significance of the transsulfuration enzymes for H2S production in murine tissues","volume":"15","author":"Kabil","year":"2011","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.niox.2020.12.002_bib31","first-page":"245","article-title":"Conversion of \u03b1-keto analogue of cysteine to pyruvate and sulfur","volume":"12","author":"Meister","year":"1953","journal-title":"Fed. Proc."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0021-9258(19)77248-2","article-title":"b-Mercapto-pyruvate, a substrate for rhodanese","volume":"205","author":"Wood","year":"1953","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib33","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1089\/ars.2013.5339","article-title":"Enzymology of H2S biogenesis, decay and signaling","volume":"20","author":"Kabil","year":"2014","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.niox.2020.12.002_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-9528-8_1","article-title":"Synthesis, metabolism, and signaling mechanisms of hydrogen sulfide: an overview","volume":"2007","author":"Be\u0142towski","year":"2019","journal-title":"Methods Mol. Biol."},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib35","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1124\/pr.117.014050","article-title":"International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors","volume":"69","author":"Szabo","year":"2017","journal-title":"Pharmacol. Rev."},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib36","doi-asserted-by":"crossref","first-page":"L684","DOI":"10.1152\/ajplung.00361.2013","article-title":"Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia","volume":"306","author":"Madurga","year":"2014","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090965","article-title":"Exogenous hydrogen sulfide (H2S) protects alveolar growth in experimental O2-induced neonatal lung injury","volume":"9","author":"Vadivel","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib38","doi-asserted-by":"crossref","first-page":"L710","DOI":"10.1152\/ajplung.00134.2015","article-title":"The H2S-generating enzymes cystathionine beta-synthase and cystathionine gamma-lyase play a role in vascular development during normal lung alveolarization","volume":"309","author":"Madurga","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.niox.2020.12.002_bib39","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1038\/srep01986","article-title":"Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria","volume":"3","author":"Nagahara","year":"2013","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.niox.2020.12.002_bib40","first-page":"185","article-title":"Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia","volume":"10","author":"Nardiello","year":"2017","journal-title":"Dis Model Mech"},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib41","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.201809448","article-title":"Targeting miR-34a\/Pdgfra interactions partially corrects alveologenesis in experimental bronchopulmonary dysplasia","volume":"11","author":"Ruiz-Camp","year":"2019","journal-title":"EMBO Mol. Med."},{"issue":"6","key":"10.1016\/j.niox.2020.12.002_bib42","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1261\/rna.063206.117","article-title":"Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit","volume":"24","author":"H\u00f6nig","year":"2018","journal-title":"RNA"},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib43","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib44","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1161\/ATVBAHA.114.303534","article-title":"Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension","volume":"34","author":"Nave","year":"2014","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"8","key":"10.1016\/j.niox.2020.12.002_bib45","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1152\/physiolgenomics.00026.2017","article-title":"Perturbations to lysyl oxidase expression broadly influence the transcriptome of lung fibroblasts","volume":"49","author":"Mi\u017e\u00edkov\u00e1","year":"2017","journal-title":"Physiol. Genom."},{"issue":"12","key":"10.1016\/j.niox.2020.12.002_bib46","doi-asserted-by":"crossref","first-page":"L893","DOI":"10.1152\/ajplung.00267.2013","article-title":"Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia","volume":"305","author":"Madurga","year":"2013","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib47","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.aanat.2013.04.011","article-title":"Design-based stereology: planning, volumetry and sampling are crucial steps for a successful study","volume":"196","author":"Tschanz","year":"2014","journal-title":"Ann. Anat."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib48","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1365-2818.2010.03481.x","article-title":"A simple tool for stereological assessment of digital images: the STEPanizer","volume":"243","author":"Tschanz","year":"2011","journal-title":"J. Microsc."},{"key":"10.1016\/j.niox.2020.12.002_bib49","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/978-1-62703-056-4_18","article-title":"Stereology and morphometry of lung tissue","volume":"931","author":"M\u00fchlfeld","year":"2013","journal-title":"Methods Mol. Biol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib50","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1183\/09031936.00109407","article-title":"Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice","volume":"31","author":"Fehrenbach","year":"2008","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib51","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/ar.20747","article-title":"Stereological estimates of alveolar number and size and capillary length and surface area in mice lungs","volume":"292","author":"Knust","year":"2009","journal-title":"Anat. Rec."},{"key":"10.1016\/j.niox.2020.12.002_bib52","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/B978-0-12-407239-8.00012-4","article-title":"Stereology of the lung","volume":"113","author":"Schneider","year":"2013","journal-title":"Methods Cell Biol."},{"issue":"6","key":"10.1016\/j.niox.2020.12.002_bib53","doi-asserted-by":"crossref","first-page":"L526","DOI":"10.1152\/ajplung.00047.2015","article-title":"A review of recent developments and applications of morphometry\/stereology in lung research","volume":"309","author":"M\u00fchlfeld","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib54","doi-asserted-by":"crossref","first-page":"L205","DOI":"10.1152\/ajplung.00427.2012","article-title":"Quantitative microscopy of the lung: a problem-based approach. Part 2: stereological parameters and study designs in various diseases of the respiratory tract","volume":"305","author":"M\u00fchlfeld","year":"2013","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib55","doi-asserted-by":"crossref","first-page":"L15","DOI":"10.1152\/ajplung.00429.2012","article-title":"Quantitative microscopy of the lung: a problem-based approach. Part 1: basic principles of lung stereology","volume":"305","author":"Ochs","year":"2013","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib56","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1164\/rccm.200809-1522ST","article-title":"ATS\/ERS joint task force on quantitative assessment of lung structure, an official research policy statement of the American thoracic society\/European respiratory society: standards for quantitative assessment of lung structure","volume":"181","author":"Hsia","year":"2010","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"6","key":"10.1016\/j.niox.2020.12.002_bib57","doi-asserted-by":"crossref","first-page":"L882","DOI":"10.1152\/ajplung.00492.2016","article-title":"Stereological monitoring of mouse lung alveolarization from the early postnatal period to adulthood","volume":"312","author":"Pozarska","year":"2017","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib58","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/joa.12773","article-title":"Stereological analysis of individual lung lobes during normal and aberrant mouse lung alveolarisation","volume":"232","author":"Hoang","year":"2018","journal-title":"J. Anat."},{"issue":"5090","key":"10.1016\/j.niox.2020.12.002_bib59","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1126\/science.1361684","article-title":"NO news is good news","volume":"258","author":"Culotta","year":"1992","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib60","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1038\/s41467-017-01311-y","article-title":"Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics","volume":"8","author":"Akaike","year":"2017","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib61","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/jnc.12698","article-title":"Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons","volume":"130","author":"Miyamoto","year":"2014","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib62","first-page":"66","article-title":"Mental deficiency and a new aminoaciduria","volume":"117","author":"Ampola","year":"1969","journal-title":"Am. J. Dis. Child."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib63","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/0006-2944(81)90035-1","article-title":"3-mercaptolactate cysteine disulfiduria: biochemical studies on affected and unaffected members of a family","volume":"26","author":"Hannestad","year":"1981","journal-title":"Biochem. Med."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib64","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21030818","article-title":"Increased urinary 3-mercaptolactate excretion and enhanced passive systemic anaphylaxis in mice lacking mercaptopyruvate sulfurtransferase, a model of mercaptolactate-cysteine disulfiduria","volume":"21","author":"Akahoshi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib65","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/jb\/mvp111","article-title":"Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide","volume":"146","author":"Shibuya","year":"2009","journal-title":"J. Biochem."},{"issue":"1","key":"10.1016\/j.niox.2020.12.002_bib66","doi-asserted-by":"crossref","first-page":"H71","DOI":"10.1152\/ajpheart.00574.2014","article-title":"MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery","volume":"310","author":"Kuo","year":"2016","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.niox.2020.12.002_bib67","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.niox.2017.10.010","article-title":"The mechanism of action and role of hydrogen sulfide in the control of vascular tone","volume":"81","author":"Dongo","year":"2018","journal-title":"Nitric Oxide"},{"issue":"4","key":"10.1016\/j.niox.2020.12.002_bib68","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0006-291X(03)00256-0","article-title":"The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats","volume":"302","author":"Chunyu","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.niox.2020.12.002_bib69","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1042\/BJ20110841","article-title":"Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide","volume":"439","author":"Mikami","year":"2011","journal-title":"Biochem. J."},{"issue":"7","key":"10.1016\/j.niox.2020.12.002_bib70","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1002\/ppul.24304","article-title":"Mouse genetic background impacts susceptibility to hyperoxia-driven perturbations to lung maturation","volume":"54","author":"Tiono","year":"2019","journal-title":"Pediatr. Pulmonol."},{"issue":"13","key":"10.1016\/j.niox.2020.12.002_bib71","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1089\/ars.2013.5782","article-title":"The thioredoxin system in neonatal lung disease","volume":"21","author":"Tipple","year":"2014","journal-title":"Antioxidants Redox Signal."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib72","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1165\/rcmb.2008-0224OC","article-title":"Alterations of the thioredoxin system by hyperoxia: implications for alveolar development","volume":"41","author":"Tipple","year":"2009","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"5","key":"10.1016\/j.niox.2020.12.002_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/antiox8050116","article-title":"Novel characterization of antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice: overexpression of the evolutionarily-related enzyme rhodanese","volume":"8","author":"Nagahara","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.niox.2020.12.002_bib74","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.vph.2017.05.004","article-title":"A critical role for cystathionine-b-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery","volume":"93\u201395","author":"Donovan","year":"2017","journal-title":"Vasc. Pharmacol."}],"container-title":["Nitric Oxide"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860320302135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860320302135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T18:06:04Z","timestamp":1761069964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089860320302135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":74,"alternative-id":["S1089860320302135"],"URL":"https:\/\/doi.org\/10.1016\/j.niox.2020.12.002","relation":{},"ISSN":["1089-8603"],"issn-type":[{"value":"1089-8603","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The H2S-generating enzyme 3-mercaptopyruvate sulfurtransferase regulates pulmonary vascular smooth muscle cell migration and proliferation but does not impact normal or aberrant lung development","name":"articletitle","label":"Article Title"},{"value":"Nitric Oxide","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.niox.2020.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}