{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:57:54Z","timestamp":1771635474570,"version":"3.50.1"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01 HL103455"],"award-info":[{"award-number":["P01 HL103455"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL125886"],"award-info":[{"award-number":["R01 HL125886"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002590","name":"American Lung Association","doi-asserted-by":"publisher","award":["RG-498514"],"award-info":[{"award-number":["RG-498514"]}],"id":[{"id":"10.13039\/100002590","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nitric Oxide"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.niox.2021.10.001","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T02:20:36Z","timestamp":1634178036000},"page":"60-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Direct measurement of nitric oxide (NO) production rates from enzymes using ozone-based gas-phase chemiluminescence (CL)"],"prefix":"10.1016","volume":"117","author":[{"given":"Courtney E.","family":"Sparacino-Watkins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Jack R.","family":"Lancaster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.freeradbiomed.2008.03.020","article-title":"The chemical biology of nitric oxide: implications in cellular signaling","volume":"45","author":"Thomas","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.niox.2021.10.001_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.niox.2020.07.004","article-title":"The solution chemistry of nitric oxide and other reactive nitrogen species","volume":"103","author":"Ford","year":"2020","journal-title":"Nitric Oxide"},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1073\/pnas.98.1.355","article-title":"The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2","volume":"98","author":"Thomas","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1006\/niox.1996.0112","article-title":"A\u00a0tutorial on the diffusibility and reactivity of free nitric oxide","volume":"1","author":"Lancaster","year":"1997","journal-title":"Nitric Oxide"},{"issue":"24","key":"10.1016\/j.niox.2021.10.001_bib5","doi-asserted-by":"crossref","first-page":"8894","DOI":"10.1073\/pnas.0400453101","article-title":"Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide","volume":"101","author":"Thomas","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.niox.2021.10.001_bib6","doi-asserted-by":"crossref","first-page":"H2026","DOI":"10.1152\/ajpheart.00407.2006","article-title":"Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation","volume":"291","author":"Gladwin","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib7","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1152\/physrev.00036.2017","article-title":"Sources of vascular nitric oxide and reactive oxygen species and their regulation","volume":"99","author":"Tejero","year":"2019","journal-title":"Physiol. Rev."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0014-5793(98)00430-X","article-title":"Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions","volume":"427","author":"Millar","year":"1998","journal-title":"FEBS (Fed. Eur. Biochem. Soc.) Lett."},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib9","first-page":"1150","volume":"42","author":"Li","year":"2003","journal-title":"Characterization of the Magnitude and Kinetics of Xanthine Oxidase-Catalyzed Nitrate Reduction:Evaluation of Its Role in Nitrite and Nitric Oxide Generation in Anoxic Tissues .Biochemistry"},{"issue":"17","key":"10.1016\/j.niox.2021.10.001_bib10","doi-asserted-by":"crossref","first-page":"16939","DOI":"10.1074\/jbc.M314336200","article-title":"Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation","volume":"279","author":"Li","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"issue":"49","key":"10.1016\/j.niox.2021.10.001_bib11","doi-asserted-by":"crossref","first-page":"33850","DOI":"10.1074\/jbc.M109.019125","article-title":"Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite","volume":"284","author":"Li","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"issue":"15","key":"10.1016\/j.niox.2021.10.001_bib12","doi-asserted-by":"crossref","first-page":"10345","DOI":"10.1074\/jbc.M114.555177","article-title":"Nitrite reductase and NO synthase activity of the mitochondrial molybdopterin enzymes mARC1 and mARC2","volume":"289","author":"Sparacino-Watkins","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib13","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1089\/ars.2013.5397","article-title":"Sulfite oxidase catalyzes single-electron transfer at molybdenum domain to reduce nitrite to nitric oxide","volume":"23","author":"Wang","year":"2015","journal-title":"Antioxidants Redox Signal."},{"issue":"26","key":"10.1016\/j.niox.2021.10.001_bib14","doi-asserted-by":"crossref","first-page":"17855","DOI":"10.1074\/jbc.M801785200","article-title":"Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase","volume":"283","author":"Li","year":"2008","journal-title":"J.\u00a0Biol. Chem."},{"issue":"20","key":"10.1016\/j.niox.2021.10.001_bib15","doi-asserted-by":"crossref","first-page":"18277","DOI":"10.1074\/jbc.M110.159541","article-title":"Human neuroglobin functions as a redox-regulated nitrite reductase","volume":"286","author":"Tiso","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/abbi.1998.0785","article-title":"Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems","volume":"357","author":"Samouilov","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"issue":"6","key":"10.1016\/j.niox.2021.10.001_bib17","doi-asserted-by":"crossref","first-page":"H2068","DOI":"10.1152\/ajpheart.00525.2009","article-title":"Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation","volume":"297","author":"Aamand","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.niox.2021.10.001_bib18","series-title":"Oxygen Regulates Tissue Nitrite Metabolism","author":"Curtis","year":"2012"},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib19","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.109.891077","article-title":"Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase\u2013dependent nitric oxide generation","volume":"121","author":"Zuckerbraun","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.niox.2021.10.001_bib20","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1039\/tf9646000359","article-title":"Kinetics of the chemiluminescent reaction between nitric oxide and ozone","volume":"60","author":"Clyne","year":"1964","journal-title":"Trans. Faraday Soc."},{"key":"10.1016\/j.niox.2021.10.001_bib21","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1039\/tf9676300915","article-title":"Mechanism of chemiluminescent reaction between nitric oxide and ozone","volume":"63","author":"Clough","year":"1967","journal-title":"Trans. Faraday Soc."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib22","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/1058-6741(92)90045-Y","article-title":"Nitric oxide measurement by chemiluminescence detection","volume":"1","author":"Bates","year":"1992","journal-title":"Neuroprotocols"},{"issue":"12","key":"10.1016\/j.niox.2021.10.001_bib23","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1021\/ac60348a042","article-title":"Optimization of the operating parameters of chemiluminescent nitric oxide detectors","volume":"46","author":"Steffenson","year":"1974","journal-title":"Anal. Chem."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib24","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1021\/cr00061a003","article-title":"Chemiluminescence in the reactions of ozone","volume":"84","author":"Toby","year":"1984","journal-title":"Chem. Rev."},{"issue":"21","key":"10.1016\/j.niox.2021.10.001_bib25","first-page":"783","article-title":"The mechanism of the chemiluminescent reaction between nitric oxide and ozone","author":"Clough","year":"1966","journal-title":"Chem. Commun."},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib26","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1021\/acs.jpca.8b08812","article-title":"Mechanism of the chemiluminescent reaction between nitric oxide and ozone","volume":"123","author":"Gudem","year":"2019","journal-title":"J.\u00a0Phys. Chem."},{"issue":"8","key":"10.1016\/j.niox.2021.10.001_bib27","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1051\/analusis:2000280686","article-title":"Principles and recent analytical applications of chemiluminescence","volume":"28","author":"Garc\u00eda-Campa\u00f1a","year":"2000","journal-title":"Analusis"},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib28","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1063\/1.1740150","article-title":"Kinetics of the fast gas phase reaction between ozone and nitric oxide","volume":"22","author":"Johnston","year":"1954","journal-title":"J.\u00a0Chem. Phys."},{"issue":"6","key":"10.1016\/j.niox.2021.10.001_bib29","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1021\/ac60288a034","article-title":"Homogeneous chemiluminescent measurement of nitric oxide with ozone. Implications for continuous selective monitoring of gaseous air pollutants","volume":"42","author":"Fontijn","year":"1970","journal-title":"Anal. Chem."},{"key":"10.1016\/j.niox.2021.10.001_bib30","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0076-6879(96)68011-2","article-title":"Chemiluminescence headspace-gas analysis for determination of nitric oxide formation in biological systems","author":"Brien","year":"1996"},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0160-5402(91)90019-2","article-title":"Quantitation of nitric oxide formation from nitrovasodilator drugs by chemiluminescence analysis of headspace gas","volume":"25","author":"Brien","year":"1991","journal-title":"J.\u00a0Pharmacol. Methods"},{"issue":"1\u20132","key":"10.1016\/j.niox.2021.10.001_bib32","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jchromb.2006.12.012","article-title":"Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence","volume":"851","author":"MacArthur","year":"2007","journal-title":"J.\u00a0Chromatogr. B"},{"issue":"11","key":"10.1016\/j.niox.2021.10.001_bib33","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1021\/ac50061a029","article-title":"Determination of trace levels of nitric oxide in aqueous solution","volume":"52","author":"Zafiriou","year":"1980","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib34","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0003-2697(87)90557-4","article-title":"Use of a chemiluminescence detector for quantitation of nitric oxide produced in assays of denitrifying enzymes","volume":"166","author":"Pai","year":"1987","journal-title":"Anal. Biochem."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib35","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/bmc.1130040311","article-title":"Continuous flow determination of nitrite with membrane separation\/chemiluminescence detection","volume":"4","author":"Aoki","year":"1990","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.niox.2021.10.001_bib36","series-title":"Nitric Oxide Protocols","first-page":"111","article-title":"The measurement of NO in biological systems using chemiluminescence","author":"Michelakis","year":"1998"},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib37","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/02652038709373624","article-title":"A\u00a0rapid method for the determination of nitrate and nitrite by chemiluminescence","volume":"4","author":"Walters","year":"1987","journal-title":"Food Addit. Contam."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib38","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1021\/ac50052a028","article-title":"Determination of nitrate and nitrite at the parts per billion level by chemiluminescence","volume":"52","author":"Cox","year":"1980","journal-title":"Anal. Chem."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib39","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1006\/abio.1998.2609","article-title":"Development of chemiluminescence-based methods for specific quantitation of nitrosylated thiols","volume":"258","author":"Samouilov","year":"1998","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.niox.2021.10.001_bib40","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0076-6879(08)36007-8","article-title":"Chapter seven - chemiluminescence quantification of NO and its derivatives in liquid samples","author":"Laver","year":"2008"},{"key":"10.1016\/j.niox.2021.10.001_bib41","series-title":"Reactive Species Detection in Biology","first-page":"13","article-title":"Chapter 2 - chemistry of reactive species","author":"Villamena","year":"2017"},{"key":"10.1016\/j.niox.2021.10.001_bib42","volume":"vol. 3229","author":"Maahs","year":"1975"},{"issue":"11","key":"10.1016\/j.niox.2021.10.001_bib43","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.5194\/acp-6-3625-2006","article-title":"Evaluated kinetic and photochemical data for atmospheric chemistry: volume II\u2013gas phase reactions of organic species","volume":"6","author":"Atkinson","year":"2006","journal-title":"Atmos. Chem. Phys."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib44","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/clinchem\/48.3.570","article-title":"Optimization of nitric oxide chemiluminescence operating conditions for measurement of plasma nitrite and nitrate","volume":"48","author":"Bateman","year":"2002","journal-title":"Clin. Chem."},{"issue":"4758","key":"10.1016\/j.niox.2021.10.001_bib45","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/189056a0","article-title":"Rates of the reactions of nitrogen atoms with oxygen and with nitric oxide","volume":"189","author":"Clyne","year":"1961","journal-title":"Nature"},{"key":"10.1016\/j.niox.2021.10.001_bib46","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1039\/DF9623300139","article-title":"Mechanism of chemiluminescent reactions involving nitric oxide\u2014\u2013the H+ NO reaction","volume":"33","author":"Clyne","year":"1962","journal-title":"Discuss. Faraday Soc."},{"issue":"10","key":"10.1016\/j.niox.2021.10.001_bib47","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1021\/es60057a003","article-title":"Chemiluminescent reactions of ozone with olefins and sulfides","volume":"5","author":"Pitts","year":"1971","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib48","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1021\/es950442o","article-title":"Carbonyl products of the gas-phase reaction of ozone with simple alkenes","volume":"30","author":"Grosjean","year":"1996","journal-title":"Environ. Sci. Technol."},{"issue":"8","key":"10.1016\/j.niox.2021.10.001_bib49","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1021\/j100575a004","article-title":"Reaction between ozone and hydrogen sulfide","volume":"79","author":"Glavas","year":"1975","journal-title":"J.\u00a0Phys. Chem."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib50","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1139\/v84-073","article-title":"Chemiluminescence from the reactions of ozone with sulphur compounds","volume":"62","author":"Arora","year":"1984","journal-title":"Can. J. Chem."},{"issue":"3","key":"10.1016\/j.niox.2021.10.001_bib51","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1163\/156856794X00351","article-title":"Kinetics and products of the gas-phase reactions of O 3 with amines and related compounds","volume":"20","author":"Tuazon","year":"1994","journal-title":"Res. Chem. Intermed."},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib52","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1021\/ja00368a050","article-title":"Single-collision chemiluminescent reactions of ozone with hydrogen sulfide and methyl mercaptan","volume":"104","author":"Glinski","year":"1982","journal-title":"J.\u00a0Am. Chem. Soc."},{"issue":"17","key":"10.1016\/j.niox.2021.10.001_bib53","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1021\/j150617a005","article-title":"The chemiluminescent reaction of ozone with methyl mercaptan","volume":"85","author":"Glinski","year":"1981","journal-title":"J.\u00a0Phys. Chem."},{"issue":"1443","key":"10.1016\/j.niox.2021.10.001_bib54","first-page":"380","article-title":"The kinetics of elementary reactions involving the oxides of sulphur III. The chemiluminescent reaction between sulphur monoxide and ozone","volume":"295","author":"Halstead","year":"1966","journal-title":"Proc. Roy. Soc. Lond. Math. Phys. Sci."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib55","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1096\/fasebj.7.2.8440411","article-title":"Measurement of nitric oxide in biological models","volume":"7","author":"Archer","year":"1993","journal-title":"Faseb. J."},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib56","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1111\/bph.14887","article-title":"Carbonic anhydrase II does not regulate nitrite dependent nitric oxide formation and vasodilation","volume":"177","author":"Wang","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.niox.2021.10.001_bib57","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0022-3565(25)13024-3","article-title":"Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells","volume":"253","author":"Chung","year":"1990","journal-title":"J.\u00a0Pharmacol. Exp. Therapeut."},{"issue":"12","key":"10.1016\/j.niox.2021.10.001_bib58","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1093\/jxb\/erl070","article-title":"Nitric oxide (NO) detection by DAF fluorescence and chemiluminescence: a comparison using abiotic and biotic NO sources","volume":"57","author":"Planchet","year":"2006","journal-title":"J.\u00a0Exp. Bot."},{"key":"10.1016\/j.niox.2021.10.001_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.redox.2016.05.002","article-title":"Direct measurement of actual levels of nitric oxide (NO) in cell culture conditions using soluble NO donors","volume":"9","author":"He","year":"2016","journal-title":"Redox Biology"},{"issue":"4","key":"10.1016\/j.niox.2021.10.001_bib60","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1006\/niox.2000.0289","article-title":"Evaluation of nitric oxide synthase activity and inhibition kinetics by chemiluminescence","volume":"4","author":"Maurer","year":"2000","journal-title":"Nitric Oxide"},{"issue":"18","key":"10.1016\/j.niox.2021.10.001_bib61","doi-asserted-by":"crossref","first-page":"12546","DOI":"10.1074\/jbc.M511803200","article-title":"Characterization of the mechanism of cytochrome P450 reductase-cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates","volume":"281","author":"Li","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"issue":"43","key":"10.1016\/j.niox.2021.10.001_bib62","doi-asserted-by":"crossref","first-page":"36623","DOI":"10.1074\/jbc.M112.342378","article-title":"Characterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditions","volume":"287","author":"Li","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"issue":"30","key":"10.1016\/j.niox.2021.10.001_bib63","doi-asserted-by":"crossref","first-page":"8538","DOI":"10.1073\/pnas.1522670113","article-title":"Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells","volume":"113","author":"Corti","year":"2016","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"12","key":"10.1016\/j.niox.2021.10.001_bib64","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1042\/BCJ20190143","article-title":"Mechanism of nitrite-dependent NO synthesis by human sulfite oxidase","volume":"476","author":"Bender","year":"2019","journal-title":"Biochem. J."},{"issue":"11","key":"10.1016\/j.niox.2021.10.001_bib65","doi-asserted-by":"crossref","first-page":"7757","DOI":"10.1074\/jbc.275.11.7757","article-title":"Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase","volume":"275","author":"Godber","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"issue":"27","key":"10.1016\/j.niox.2021.10.001_bib66","doi-asserted-by":"crossref","first-page":"24482","DOI":"10.1074\/jbc.M011648200","article-title":"Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues","volume":"276","author":"Li","year":"2001","journal-title":"J.\u00a0Biol. Chem."},{"issue":"1","key":"10.1016\/j.niox.2021.10.001_bib67","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.niox.2004.01.004","article-title":"Formation of nitric oxide from nitrous acid in ischemic tissue and skin","volume":"10","author":"Butler","year":"2004","journal-title":"Nitric Oxide - Biology and Chemistry"},{"issue":"12","key":"10.1016\/j.niox.2021.10.001_bib68","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1038\/nm954","article-title":"Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation","volume":"9","author":"Cosby","year":"2003","journal-title":"Nat. Med."}],"container-title":["Nitric Oxide"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860321001051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860321001051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T18:07:23Z","timestamp":1761070043000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089860321001051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":68,"alternative-id":["S1089860321001051"],"URL":"https:\/\/doi.org\/10.1016\/j.niox.2021.10.001","relation":{},"ISSN":["1089-8603"],"issn-type":[{"value":"1089-8603","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct measurement of nitric oxide (NO) production rates from enzymes using ozone-based gas-phase chemiluminescence (CL)","name":"articletitle","label":"Article Title"},{"value":"Nitric Oxide","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.niox.2021.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}