{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:07:43Z","timestamp":1792069663876,"version":"4.4.0"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018973","name":"Lovely Professional University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018973","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nitric Oxide"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.niox.2024.01.004","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T11:52:25Z","timestamp":1705492345000},"page":"20-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"special_numbering":"C","title":["Hydrogen sulfide (H2S) metabolism: Unraveling cellular regulation, disease implications, and therapeutic prospects for precision medicine"],"prefix":"10.1016","volume":"144","author":[{"given":"Tejasvi","family":"Pandey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6354-9525","authenticated-orcid":false,"given":"Vivek","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib1","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.3390\/antiox12091737","article-title":"Hydrogen sulfide: an emerging regulator of oxidative stress and cellular homeostasis\u2014a comprehensive One-Year review","volume":"12","author":"Munteanu","year":"2023","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/s41392-022-01078-9","article-title":"The role of histone modifications: from neurodevelopment to neurodiseases","volume":"7","author":"Park","year":"2022","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib3","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/s41392-023-01343-5","article-title":"Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases","volume":"8","author":"Ji","year":"2023","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"10","key":"10.1016\/j.niox.2024.01.004_bib4","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1002\/jnr.25110","article-title":"Targeting mitochondria in the regulation of neurodegenerative diseases: a comprehensive review","volume":"100","author":"Maurya","year":"2022","journal-title":"J. Neurosci. Res."},{"issue":"11","key":"10.1016\/j.niox.2024.01.004_bib5","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/s41576-022-00501-9","article-title":"tRNA dysregulation and disease","volume":"23","author":"Orellana","year":"2022","journal-title":"Nat. Rev. Genet."},{"issue":"14","key":"10.1016\/j.niox.2024.01.004_bib6","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.devcel.2022.06.010","article-title":"Genetic variation associated with condensate dysregulation in disease","volume":"57","author":"Banani","year":"2022","journal-title":"Dev. Cell"},{"issue":"5","key":"10.1016\/j.niox.2024.01.004_bib7","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1111\/febs.16462","article-title":"Dysregulated RNA processing and metabolism: a new hallmark of ageing and provocation for cellular senescence","volume":"290","author":"Harries","year":"2023","journal-title":"FEBS J."},{"issue":"7937","key":"10.1016\/j.niox.2024.01.004_bib8","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/s41586-022-05439-w","article-title":"APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes","volume":"611","author":"Blanchard","year":"2022","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib9","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.3390\/antiox12091759","article-title":"Reactive sulfur species in biology and medicine","volume":"12","author":"Khodade","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.niox.2024.01.004_bib10","series-title":"Advances in Gas Therapeutics for Wound Healing: Mechanisms, Delivery Materials, and Prospects","author":"Ding","year":"2023"},{"key":"10.1016\/j.niox.2024.01.004_bib11","article-title":"Ultrasmall self-cascade AuNP@ FeS nanozyme for H2S-amplified ferroptosis therapy","volume":"39","author":"Zhan","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.niox.2024.01.004_bib12","series-title":"Semiconducting Polymers for Cancer Immunotherapy","author":"Li","year":"2023"},{"issue":"5","key":"10.1016\/j.niox.2024.01.004_bib13","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1039\/D2TB02090D","article-title":"Bilayer dressing based on aerogel\/electrospun mats with self-catalytic hydrogen sulfide generation and enhanced antioxidant ability","volume":"11","author":"Han","year":"2023","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.niox.2024.01.004_bib14","article-title":"Carbon monoxide therapy: a promising strategy for cancer","author":"Wang","year":"2023","journal-title":"J. Mater. Chem. B"},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib15","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.3390\/antiox12091780","article-title":"Methanethiol: a scent mark of dysregulated sulfur metabolism in cancer","volume":"12","author":"Philipp","year":"2023","journal-title":"Antioxidants"},{"issue":"6","key":"10.1016\/j.niox.2024.01.004_bib16","doi-asserted-by":"crossref","first-page":"688","DOI":"10.3390\/metabo13060688","article-title":"Sulfur-containing amino acids, hydrogen sulfide, and sulfur compounds on kidney health and disease","volume":"13","author":"Chen","year":"2023","journal-title":"Metabolites"},{"issue":"3","key":"10.1016\/j.niox.2024.01.004_bib17","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3390\/pathophysiology29030044","article-title":"Dysregulated sulfide metabolism in multiple sclerosis: serum and vascular endothelial inflammatory responses","volume":"29","author":"Veerareddy","year":"2022","journal-title":"Pathophysiology"},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib18","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2017225118","article-title":"Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3\u03b2 and inhibiting Tau hyperphosphorylation","volume":"118","author":"Giovinazzo","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2024.01.004_bib19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.freeradbiomed.2022.05.005","article-title":"Cysteine metabolism and hydrogen sulfide signaling in Huntington's disease","volume":"186","author":"Paul","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib20","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1039\/D3CB00070B","article-title":"A mitochondria-targeted chemiluminescent probe for detection of hydrogen sulfide in cancer cells, human serum and in vivo","volume":"4","author":"Gunduz","year":"2023","journal-title":"RSC Chemical Biology"},{"issue":"3","key":"10.1016\/j.niox.2024.01.004_bib21","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3390\/antiox10030429","article-title":"Trends in H2S-donors chemistry and their effects in cardiovascular diseases","volume":"10","author":"Corvino","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.niox.2024.01.004_bib22","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.3389\/fphar.2019.01568","article-title":"Role of endothelial dysfunction in cardiovascular diseases: the link between inflammation and hydrogen sulfide","volume":"10","author":"Sun","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib23","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.3390\/ijms22042194","article-title":"The potential of hydrogen sulfide donors in treating cardiovascular diseases","volume":"22","author":"Wang","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"24","key":"10.1016\/j.niox.2024.01.004_bib24","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.2174\/1568026621666210831163817","article-title":"Recent development of hydrogen sulfide therapeutics in the treatment of cardiovascular diseases","volume":"21","author":"Peng","year":"2021","journal-title":"Curr. Top. Med. Chem."},{"issue":"12","key":"10.1016\/j.niox.2024.01.004_bib25","doi-asserted-by":"crossref","first-page":"6562","DOI":"10.3390\/ijms22126562","article-title":"The hidden role of hydrogen sulfide metabolism in cancer","volume":"22","author":"Wang","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib26","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/bph.14824","article-title":"Modulation of the functions of myeloid\u2010derived suppressor cells: a new strategy of hydrogen sulfide anti\u2010cancer effects","volume":"177","author":"De Cicco","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2017.7058","article-title":"A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?","volume":"31","author":"Cao","year":"2019","journal-title":"Antioxidants Redox Signal."},{"issue":"10","key":"10.1016\/j.niox.2024.01.004_bib28","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.7150\/ijms.36516","article-title":"Potential for therapeutic use of hydrogen sulfide in oxidative stress-induced neurodegenerative diseases","volume":"16","author":"Tabassum","year":"2019","journal-title":"Int. J. Med. Sci."},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib29","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.3390\/molecules26092411","article-title":"Hydrogen sulfide: novel endogenous and exogenous modulator of oxidative stress in retinal degeneration diseases","volume":"26","author":"Li","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.niox.2024.01.004_bib30","series-title":"Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges","first-page":"1","author":"Sharif","year":"2023"},{"key":"10.1016\/j.niox.2024.01.004_bib31","doi-asserted-by":"crossref","DOI":"10.1039\/D3CB00073G","article-title":"Small molecules and conjugates as theranostic agents","author":"Pratihar","year":"2023","journal-title":"RSC Chemical Biology"},{"issue":"3","key":"10.1016\/j.niox.2024.01.004_bib32","doi-asserted-by":"crossref","first-page":"652","DOI":"10.3390\/antiox12030652","article-title":"Advances of H2S in regulating neurodegenerative diseases by preserving mitochondria function","volume":"12","author":"Zhou","year":"2023","journal-title":"Antioxidants"},{"issue":"5","key":"10.1016\/j.niox.2024.01.004_bib33","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3390\/antiox12051095","article-title":"Protective roles of hydrogen sulfide in alzheimer's disease and traumatic brain injury","volume":"12","author":"Paul","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.niox.2024.01.004_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.111745","article-title":"Design and synthesis of H2S-donor hybrids: a new treatment for Alzheimer's disease?","volume":"184","author":"Sestito","year":"2019","journal-title":"Eur. J. Med. Chem."},{"issue":"33","key":"10.1016\/j.niox.2024.01.004_bib35","doi-asserted-by":"crossref","first-page":"11573","DOI":"10.1021\/acs.analchem.2c01850","article-title":"Simultaneous sensing of H2S and ATP with a two-photon fluorescent probe in Alzheimer's disease: toward understanding Why H2S regulates glutamate-induced ATP dysregulation","volume":"94","author":"Sun","year":"2022","journal-title":"Anal. Chem."},{"issue":"8","key":"10.1016\/j.niox.2024.01.004_bib36","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1002\/alz.12305","article-title":"Plasma hydrogen sulfide: a biomarker of Alzheimer's disease and related dementias","volume":"17","author":"Disbrow","year":"2021","journal-title":"Alzheimer's Dementia"},{"issue":"6","key":"10.1016\/j.niox.2024.01.004_bib37","doi-asserted-by":"crossref","first-page":"978","DOI":"10.3390\/cells11060978","article-title":"Hydrogen sulfide produced by gut bacteria may induce Parkinson's disease","volume":"11","author":"Murros","year":"2022","journal-title":"Cells"},{"issue":"7","key":"10.1016\/j.niox.2024.01.004_bib38","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.4103\/1673-5374.301026","article-title":"Hydrogen sulfide enhances adult neurogenesis in a mouse model of Parkinson's disease","volume":"16","author":"Wang","year":"2021","journal-title":"Neural Regeneration Research"},{"key":"10.1016\/j.niox.2024.01.004_bib39","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s11010-020-03801-y","article-title":"Hydrogen sulfide alleviates oxidative stress injury and reduces apoptosis induced by MPP+ in Parkinson's disease cell model","volume":"472","author":"Liu","year":"2020","journal-title":"Mol. Cell. Biochem."},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib40","first-page":"1124","article-title":"Protective effect of hydrogen sulfide is mediated by negative regulation of epigenetic histone acetylation in Parkinson's disease","volume":"19","author":"Sun","year":"2023","journal-title":"Arch. Med. Sci.: AMS"},{"issue":"12","key":"10.1016\/j.niox.2024.01.004_bib41","doi-asserted-by":"crossref","first-page":"6720","DOI":"10.3390\/ijms23126720","article-title":"Recent advances in molecular research on hydrogen sulfide (H2S) role in diabetes mellitus (DM)\u2014a systematic review","volume":"23","author":"Munteanu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.niox.2024.01.004_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101704","article-title":"Potential role of hydrogen sulfide in diabetes-impaired angiogenesis and ischemic tissue repair","volume":"37","author":"Cheng","year":"2020","journal-title":"Redox Biol."},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib43","doi-asserted-by":"crossref","first-page":"628","DOI":"10.3390\/antiox11040628","article-title":"Reduced levels of H2S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2\/HO-1 signalling downregulation and chondrocyte dysfunction","volume":"11","author":"Pi\u00f1eiro-Ramil","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.niox.2024.01.004_bib44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.freeradbiomed.2022.01.028","article-title":"Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis","volume":"181","author":"Gong","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib45","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1039\/D3CB00070B","article-title":"A mitochondria-targeted chemiluminescent probe for detection of hydrogen sulfide in cancer cells, human serum and in vivo","volume":"4","author":"Gunduz","year":"2023","journal-title":"RSC Chemical Biology"},{"key":"10.1016\/j.niox.2024.01.004_bib46","series-title":"Microbial Biomolecules","first-page":"353","article-title":"Gut microbial metabolites and colorectal cancer","author":"Masood","year":"2023"},{"key":"10.1016\/j.niox.2024.01.004_bib47","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.niox.2024.01.004_bib48","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10725-018-0454-9","article-title":"Interaction between hydrogen sulfide and hormones in plant physiological responses","volume":"87","author":"He","year":"2019","journal-title":"Plant Growth Regul."},{"key":"10.1016\/j.niox.2024.01.004_bib49","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.plaphy.2020.11.045","article-title":"Hydrogen sulfide: a versatile gaseous molecule in plants","volume":"158","author":"Arif","year":"2021","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.niox.2024.01.004_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.mad.2022.111656","article-title":"Deletions of the cystathionine-\u03b2-synthase (CBS) and cystathionine- \u03b3-lyase (CSE) genes, involved in the control of hydrogen sulfide biosynthesis, significantly affect lifespan and fitness components of Drosophila melanogaster","volume":"203","author":"Shaposhnikov","year":"2022","journal-title":"Mech. Ageing Dev."},{"issue":"32","key":"10.1016\/j.niox.2024.01.004_bib51","doi-asserted-by":"crossref","first-page":"3662","DOI":"10.2174\/0929867321666140706142335","article-title":"Endothelial dysfunction: the link between homocysteine and hydrogen sulfide","volume":"21","author":"Pushpakumar","year":"2014","journal-title":"Curr. Med. Chem."},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib52","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1471-4159.2010.06580.x","article-title":"Hydrogen sulfide as a gasotransmitter","volume":"113","author":"Gadalla","year":"2010","journal-title":"J. Neurochem."},{"key":"10.1016\/j.niox.2024.01.004_bib53","first-page":"1","article-title":"Synthesis, metabolism, and signaling mechanisms of hydrogen sulfide: an overview","author":"Be\u0142towski","year":"2019","journal-title":"Vascular Effects of Hydrogen Sulfide: Methods and Protocols"},{"issue":"3","key":"10.1016\/j.niox.2024.01.004_bib54","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jpedsurg.2017.06.011","article-title":"Reduction of hydrogen sulfide synthesis enzymes cystathionine-\u03b2-synthase and cystathionine-\u03b3-lyase in the colon of patients with Hirschsprungs disease","volume":"53","author":"Tomuschat","year":"2018","journal-title":"J. Pediatr. Surg."},{"issue":"10","key":"10.1016\/j.niox.2024.01.004_bib55","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1038\/labinvest.2008.73","article-title":"Generation of endogenous hydrogen sulfide by cystathionine \u03b3-lyase limits renal ischemia\/reperfusion injury and dysfunction","volume":"88","author":"Tripatara","year":"2008","journal-title":"Lab. Invest."},{"key":"10.1016\/j.niox.2024.01.004_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2018.11.034","article-title":"Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)\u2014hydrogen sulfide (H2S) pathway in cancer cells","volume":"154","author":"Augsburger","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.niox.2024.01.004_bib57","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1096\/fj.12-216507","article-title":"Intramitochondrial hydrogen sulfide production by 3\u2010mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics","volume":"27","author":"M\u00f3dis","year":"2013","journal-title":"Faseb. J."},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib58","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/physrev.00028.2021","article-title":"Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs","volume":"103","author":"Cirino","year":"2023","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.niox.2024.01.004_bib59","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/397502","article-title":"Physiological implications of hydrogen sulfide in plants: pleasant exploration behind its unpleasant odour","author":"Jin","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.niox.2024.01.004_bib60","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s42994-021-00035-4","article-title":"Hydrogen sulfide (H 2 S) signaling in plant development and stress responses","volume":"2","author":"Liu","year":"2021","journal-title":"aBIOTECH"},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib61","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/s42003-019-0431-5","article-title":"Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B6","volume":"2","author":"Yang","year":"2019","journal-title":"Commun. Biol."},{"issue":"9","key":"10.1016\/j.niox.2024.01.004_bib62","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.3390\/antiox11091823","article-title":"Sequential accumulation of \u2018driver\u2019pathway mutations induces the upregulation of hydrogen-sulfide- producing enzymes in human colonic epithelial cell organoids","volume":"11","author":"Ascen\u00e7\u00e3o","year":"2022","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib63","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/physrev.00028.2021","article-title":"Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs","volume":"103","author":"Cirino","year":"2023","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.niox.2024.01.004_bib64","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8102936","article-title":"Hydrogen sulfide oxidation: adaptive changes in mitochondria of SW480 colorectal cancer cells upon exposure to hypoxia","author":"Malagrin\u00f2","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.niox.2024.01.004_bib65","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/s42003-019-0431-5","article-title":"Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B6","volume":"2","author":"Yang","year":"2019","journal-title":"Commun. Biol."},{"key":"10.1016\/j.niox.2024.01.004_bib66","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.plaphy.2020.11.045","article-title":"Hydrogen sulfide: a versatile gaseous molecule in plants","volume":"158","author":"Arif","year":"2021","journal-title":"Plant Physiol. Biochem."},{"key":"10.1016\/j.niox.2024.01.004_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.cofs.2022.100906","article-title":"Recent update on the mechanism of hydrogen sulfide improving the preservation of postharvest fruits and vegetables","author":"Wang","year":"2022","journal-title":"Curr. Opin. Food Sci."},{"issue":"2","key":"10.1016\/j.niox.2024.01.004_bib68","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3390\/antiox10020247","article-title":"Preventing developmental origins of cardiovascular disease: hydrogen sulfide as a potential target?","volume":"10","author":"Hsu","year":"2021","journal-title":"Antioxidants"},{"issue":"16","key":"10.1016\/j.niox.2024.01.004_bib69","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241612555","article-title":"The role of hydrogen sulfide (H2S) in epigenetic regulation of neurodegenerative diseases: a systematic review","volume":"24","author":"Dogaru","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.niox.2024.01.004_bib70","article-title":"Dysregulated cystathionine\u2010\u03b2\u2010synthase\/hydrogen sulfide signaling promotes chronic stress\u2010induced colonic hypermotility in rats","volume":"35","author":"Lin","year":"2023","journal-title":"Neuro Gastroenterol. Motil."},{"issue":"10","key":"10.1016\/j.niox.2024.01.004_bib71","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201845986","article-title":"Dysregulation of cystathionine \u03b3\u2010lyase promotes prostate cancer progression and metastasis","volume":"20","author":"Wang","year":"2019","journal-title":"EMBO Rep."},{"issue":"4","key":"10.1016\/j.niox.2024.01.004_bib72","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1124\/pr.117.014050","article-title":"International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors","volume":"69","author":"Szabo","year":"2017","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.niox.2024.01.004_bib73","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.jconrel.2022.09.060","article-title":"H2S responsive PEGylated poly (lipoic acid) with ciprofloxacin for targeted therapy of Salmonella","volume":"351","author":"Han","year":"2022","journal-title":"J. Contr. Release"},{"issue":"40","key":"10.1016\/j.niox.2024.01.004_bib74","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.2174\/0929867330666230126100638","article-title":"Hydrogen sulfide (H2S): as a potent modulator and therapeutic prodrug in cancer","volume":"30","author":"Faris","year":"2023","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.niox.2024.01.004_bib75","series-title":"Nitric Oxide","first-page":"57","article-title":"Cooperative interactions between NO and H2S: chemistry, biology, physiology, pathophysiology","author":"Kevil","year":"2017"},{"issue":"34","key":"10.1016\/j.niox.2024.01.004_bib76","doi-asserted-by":"crossref","first-page":"E4651","DOI":"10.1073\/pnas.1509277112","article-title":"Key bioactive reaction products of the NO\/H2S interaction are S\/N-hybrid species, polysulfides, and nitroxyl","volume":"112","author":"Cortese-Krott","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.niox.2024.01.004_bib77","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.abb.2016.09.018","article-title":"Biological chemistry of hydrogen sulfide and persulfides","volume":"617","author":"Cuevasanta","year":"2017","journal-title":"Arch. Biochem. Biophys."}],"container-title":["Nitric Oxide"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860324000107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860324000107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T18:10:03Z","timestamp":1761070203000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089860324000107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":77,"alternative-id":["S1089860324000107"],"URL":"https:\/\/doi.org\/10.1016\/j.niox.2024.01.004","relation":{},"ISSN":["1089-8603"],"issn-type":[{"value":"1089-8603","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrogen sulfide (H2S) metabolism: Unraveling cellular regulation, disease implications, and therapeutic prospects for precision medicine","name":"articletitle","label":"Article Title"},{"value":"Nitric Oxide","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.niox.2024.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}