{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T08:25:36Z","timestamp":1770971136249,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100016799","name":"Natural Science Foundation of Guangzhou Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016799","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62275135"],"award-info":[{"award-number":["62275135"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61874062"],"award-info":[{"award-number":["61874062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018978","name":"Zhejiang Federation of Humanities and Social Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018978","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nitric Oxide"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.niox.2025.05.001","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T11:41:00Z","timestamp":1747050060000},"page":"55-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Generation of high-concentration medical-grade nitric oxide via air-sourced pulsed arc discharge"],"prefix":"10.1016","volume":"157","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7877-7650","authenticated-orcid":false,"given":"Weiming","family":"Ni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haixiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yegang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.niox.2025.05.001_bib1","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000399.pub2","article-title":"Nitric oxide for respiratory failure in infants born at or near term","author":"Finer","year":"2006","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.niox.2025.05.001_bib2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/978-3-642-38664-0_11","article-title":"Inhaled nitric oxide for the treatment of pulmonary arterial hypertension","author":"Abman","year":"2013","journal-title":"Pharmacotherapy of Pulmonary Hypertension"},{"issue":"3","key":"10.1016\/j.niox.2025.05.001_bib3","article-title":"Use of inhaled nitric oxide in pediatric cardiac intensive care unit","volume":"44","author":"\u00d6zt\u00fcrk","year":"2016","journal-title":"Turk Kardiyol. Dernegi Arsivi"},{"issue":"6","key":"10.1016\/j.niox.2025.05.001_bib4","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.4187\/respcare.08856","article-title":"Inhaled nitric oxide delivery systems for mechanically ventilated and nonintubated patients: a review","volume":"66","author":"Gianni","year":"2021","journal-title":"Respir. Care"},{"key":"10.1016\/j.niox.2025.05.001_bib5","series-title":"Gas Biology Research in Clinical Practice","first-page":"43","article-title":"Clinical application of inhaled nitric oxide [M]","author":"Maruyama","year":"2011"},{"issue":"5","key":"10.1016\/j.niox.2025.05.001_bib6","doi-asserted-by":"crossref","first-page":"F337","DOI":"10.1136\/adc.2006.107490","article-title":"Is nitric oxide effective in preterm infants?","volume":"92","author":"Subhedar","year":"2007","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"issue":"16","key":"10.1016\/j.niox.2025.05.001_bib7","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1039\/C7CY00760D","article-title":"Catalytic oxidation of nitric oxide (NO) over different catalysts: an overview","volume":"7","author":"Hong","year":"2017","journal-title":"Catal. Sci. Technol."},{"issue":"2","key":"10.1016\/j.niox.2025.05.001_bib8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4187\/respcare.09308","article-title":"High-dose nitric oxide from pressurized cylinders and nitric oxide produced by an electric generator from air","volume":"67","author":"Gianni","year":"2022","journal-title":"Respir. Care"},{"key":"10.1016\/j.niox.2025.05.001_bib9","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.niox.2014.02.001","article-title":"Generation of purified nitric oxide from liquid N2O4 for the treatment of pulmonary hypertension in hypoxemic swine","volume":"37","author":"Lovich","year":"2014","journal-title":"Nitric Oxide"},{"issue":"3","key":"10.1016\/j.niox.2025.05.001_bib10","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1109\/TPS.2007.896782","article-title":"Study on production of inhaled nitric oxide for medical applications by pulsed discharge","volume":"35","author":"Hu","year":"2007","journal-title":"IEEE Trans. Plasma Sci."},{"key":"10.1016\/j.niox.2025.05.001_bib11","series-title":"Proceedings of the Digest of Technical Papers 12th IEEE International Pulsed Power Conference(Cat No 99CH36358)","article-title":"Ozone production by pulsed power in dry air","author":"Samaranayake","year":"1999"},{"key":"10.1016\/j.niox.2025.05.001_bib12","series-title":"Radicals for Life: the Various Forms of Nitric Oxide [M]","author":"Van Faassen","year":"2011"},{"issue":"1","key":"10.1016\/j.niox.2025.05.001_bib13","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1186\/s12916-022-02686-6","article-title":"An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension","volume":"20","author":"Liu","year":"2022","journal-title":"BMC Med."},{"issue":"3","key":"10.1016\/j.niox.2025.05.001_bib14","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1088\/0963-0252\/10\/3\/303","article-title":"Kinetics of ozone and nitric oxides in dielectric barrier discharges in O2\/NOx and N2\/O2\/NOx mixtures","volume":"10","author":"Stefanovic","year":"2001","journal-title":"Plasma Sources Sci. Technol."},{"issue":"4","key":"10.1016\/j.niox.2025.05.001_bib15","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/01919510600704957","article-title":"Generation of active oxidant species by pulsed dielectric barrier discharge in water-air mixtures","volume":"28","author":"Kornev","year":"2006","journal-title":"Ozone Sci. Eng."},{"issue":"7","key":"10.1016\/j.niox.2025.05.001_bib16","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1021\/ie00079a029","article-title":"Experimental study of the production of nitric oxide, nitrous oxide, and ozone in a simulated atmospheric corona","volume":"27","author":"Hill","year":"1988","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.niox.2025.05.001_bib17","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1023\/A:1021371529955","article-title":"Density and rotational temperature measurements of the OH and NO radicals produced by a gliding arc in humid air","volume":"22","author":"Benstaali","year":"2002","journal-title":"Plasma Chem. Plasma Process."},{"issue":"1","key":"10.1016\/j.niox.2025.05.001_bib18","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1109\/27.842877","article-title":"Production of nitric monoxide using pulsed discharges for a medical application","volume":"28","author":"Namihira","year":"2000","journal-title":"IEEE Trans. Plasma Sci."},{"key":"10.1016\/j.niox.2025.05.001_bib19","series-title":"Proceedings of the Digest of Technical Papers 12th IEEE International Pulsed Power Conference(Cat No 99CH36358)","article-title":"Production of nitric monoxide in dry air using pulsed discharge","author":"Namihira","year":"1999"},{"issue":"5","key":"10.1016\/j.niox.2025.05.001_bib20","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1109\/TPS.2002.807502","article-title":"Production of nitric oxide using a pulsed arc discharge","volume":"30","author":"Namihira","year":"2002","journal-title":"IEEE Trans. Plasma Sci."},{"key":"10.1016\/j.niox.2025.05.001_bib21","series-title":"Proceedings of the 2007 16th IEEE International Pulsed Power Conference","article-title":"A compact nitric oxide supply for medical application","author":"Sakai","year":"2008"},{"key":"10.1016\/j.niox.2025.05.001_bib22","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.niox.2016.08.005","article-title":"Detection and removal of impurities in nitric oxide generated from air by pulsed electrical discharge","volume":"60","author":"Yu","year":"2016","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.niox.2025.05.001_bib23","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.niox.2018.02.006","article-title":"Development of a portable mini-generator to safely produce nitric oxide for the treatment of infants with pulmonary hypertension","volume":"75","author":"Yu","year":"2018","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.niox.2025.05.001_bib24","series-title":"Proceedings of the 2023 IEEE Pulsed Power Conference (PPC)","article-title":"Development of a portable nitric oxide inhalation equipment using pulsed arc discharge","author":"Ogata","year":"2023"},{"issue":"9","key":"10.1016\/j.niox.2025.05.001_bib25","article-title":"Synthesis of NO by rotating sliding arc discharge reactor with conical-spiral electrodes","volume":"26","author":"Bingyan","year":"2024","journal-title":"Plasma Sci. Technol."},{"key":"10.1016\/j.niox.2025.05.001_bib26","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.niox.2023.05.007","article-title":"Development of nitric oxide generators to produce high-dose nitric oxide for inhalation therapy","volume":"138","author":"Yu","year":"2023","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.niox.2025.05.001_bib27","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.niox.2020.01.009","article-title":"Intratracheal injection of nitric oxide, generated from air by pulsed electrical discharge, for the treatment of pulmonary hypertension in awake ambulatory lambs","volume":"97","author":"Yu","year":"2020","journal-title":"Nitric Oxide"},{"issue":"5","key":"10.1016\/j.niox.2025.05.001_bib28","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1002\/aic.690120522","article-title":"Chemical reactions during rapid quenching of oxygen\u2010nitrogen mixtures from very high temperatures","volume":"12","author":"Ammann","year":"1966","journal-title":"AIChE J."},{"issue":"6","key":"10.1016\/j.niox.2025.05.001_bib29","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.12693\/APhysPolA.115.1104","article-title":"Nitric oxide generator based on pulsed arc discharge","volume":"115","author":"Sakai","year":"2009","journal-title":"Acta Phys. Pol., A"},{"issue":"3","key":"10.1016\/j.niox.2025.05.001_bib30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1177\/175114371301400311","article-title":"Inhaled nitric oxide: a review of the action, current literature, and an analysis of its use in the NHS today","volume":"14","author":"Mccartney","year":"2013","journal-title":"J. Intensive Care Soc."},{"issue":"14","key":"10.1016\/j.niox.2025.05.001_bib31","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1001\/jama.2020.16343","article-title":"Occupational Safety and Health Administration (OSHA) and worker safety during the COVID-19 pandemic","volume":"324","author":"Michaels","year":"2020","journal-title":"JAMA"}],"container-title":["Nitric Oxide"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860325000412?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089860325000412?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T17:37:11Z","timestamp":1762364231000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089860325000412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":31,"alternative-id":["S1089860325000412"],"URL":"https:\/\/doi.org\/10.1016\/j.niox.2025.05.001","relation":{},"ISSN":["1089-8603"],"issn-type":[{"value":"1089-8603","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation of high-concentration medical-grade nitric oxide via air-sourced pulsed arc discharge","name":"articletitle","label":"Article Title"},{"value":"Nitric Oxide","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.niox.2025.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}