{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T08:39:29Z","timestamp":1776155969084,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Learning and Memory"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.nlm.2013.06.016","type":"journal-article","created":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T05:17:47Z","timestamp":1373519867000},"page":"54-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment"],"prefix":"10.1016","volume":"105","author":[{"given":"Susan C.","family":"Su","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrii","family":"Rudenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukhee","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Huei","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nlm.2013.06.016_b0005","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cell.2007.11.041","article-title":"A beta-arrestin 2 signaling complex mediates lithium action on behavior","volume":"132","author":"Beaulieu","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.nlm.2013.06.016_b0010","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0896-6273(01)80044-1","article-title":"Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality","volume":"18","author":"Chae","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.nlm.2013.06.016_b0015","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/35096019","article-title":"A decade of CDK5","volume":"2","author":"Dhavan","year":"2001","journal-title":"Nature Reviews Molecular Cell Biology"},{"key":"10.1016\/j.nlm.2013.06.016_b0020","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.biopsych.2010.07.016","article-title":"Attention-deficit\/hyperactivity phenotype in mice lacking the cyclin-dependent kinase 5 cofactor p35","volume":"68","author":"Drerup","year":"2010","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.nlm.2013.06.016_b0025","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1093\/brain\/awr155","article-title":"Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition","volume":"134","author":"Engmann","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.nlm.2013.06.016_b0030","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.neuron.2005.10.033","article-title":"Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory","volume":"48","author":"Fischer","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.nlm.2013.06.016_b0035","doi-asserted-by":"crossref","first-page":"3700","DOI":"10.1523\/JNEUROSCI.22-09-03700.2002","article-title":"Cyclin-dependent kinase 5 is required for associative learning","volume":"22","author":"Fischer","year":"2002","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0040","doi-asserted-by":"crossref","first-page":"e25735","DOI":"10.1371\/journal.pone.0025735","article-title":"Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway","volume":"6","author":"Guan","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nlm.2013.06.016_b0045","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nn1914","article-title":"Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation","volume":"10","author":"Hawasli","year":"2007","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0050","doi-asserted-by":"crossref","first-page":"e5808","DOI":"10.1371\/journal.pone.0005808","article-title":"Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5","volume":"4","author":"Hawasli","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.nlm.2013.06.016_b0055","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.neuron.2010.08.003","article-title":"CDK5 serves as a major control point in neurotransmitter release","volume":"67","author":"Kim","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.nlm.2013.06.016_b0060","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1471-4159.2010.06748.x","article-title":"Mice lacking p35 display hyperactivity and paradoxical response to psychostimulants","volume":"114","author":"Krapacher","year":"2010","journal-title":"Journal of Neurochemistry"},{"key":"10.1016\/j.nlm.2013.06.016_b0065","doi-asserted-by":"crossref","first-page":"12742","DOI":"10.1073\/pnas.211428098","article-title":"Regulation of NMDA receptors by cyclin-dependent kinase-5","volume":"98","author":"Li","year":"2001","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.nlm.2013.06.016_b0070","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/nn.3004","article-title":"Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivity","author":"Mitra","year":"2011","journal-title":"Nature Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0075","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1523\/JNEUROSCI.4582-03.2004","article-title":"Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons","volume":"24","author":"Morabito","year":"2004","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0080","doi-asserted-by":"crossref","first-page":"25457","DOI":"10.1074\/jbc.M603469200","article-title":"The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation","volume":"281","author":"Plattner","year":"2006","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.nlm.2013.06.016_b0085","doi-asserted-by":"crossref","first-page":"9022","DOI":"10.1523\/JNEUROSCI.5216-05.2006","article-title":"Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania","volume":"26","author":"Prickaerts","year":"2006","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0090","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuron.2007.09.035","article-title":"Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK","volume":"56","author":"Samuels","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.nlm.2013.06.016_b0095","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.neuron.2008.03.021","article-title":"Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity","volume":"58","author":"Seeburg","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.nlm.2013.06.016_b0100","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/mp.2008.20","article-title":"Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania","volume":"13","author":"Shaltiel","year":"2008","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.nlm.2013.06.016_b0105","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev-cellbio-092910-154023","article-title":"Cyclin-dependent kinases in brain development and disease","volume":"27","author":"Su","year":"2011","journal-title":"Annual Review of Cell and Developmental Biology"},{"key":"10.1016\/j.nlm.2013.06.016_b0110","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1046\/j.0953-816x.2001.01803.x","article-title":"Temporally controlled targeted somatic mutagenesis in the mouse brain","volume":"14","author":"Weber","year":"2001","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.nlm.2013.06.016_b0115","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0092-8674(01)00585-2","article-title":"Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working\/episodic-like memory","volume":"107","author":"Zeng","year":"2001","journal-title":"Cell"}],"container-title":["Neurobiology of Learning and Memory"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074742713001081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074742713001081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T10:28:00Z","timestamp":1715682480000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074742713001081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":23,"alternative-id":["S1074742713001081"],"URL":"https:\/\/doi.org\/10.1016\/j.nlm.2013.06.016","relation":{},"ISSN":["1074-7427"],"issn-type":[{"value":"1074-7427","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Learning and Memory","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nlm.2013.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}