{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T06:41:34Z","timestamp":1778395294660,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Learning and Memory"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.nlm.2015.12.002","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T11:46:50Z","timestamp":1451389610000},"page":"56-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Delayed extinction and stronger drug-primed reinstatement of methamphetamine seeking in rats prenatally exposed to morphine"],"prefix":"10.1016","volume":"128","author":[{"given":"Ying-Ling","family":"Shen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Tsu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu-Yi","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsai-Wei","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pao-Luh","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruey-Ming","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Huan","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwei-Hsien","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nlm.2015.12.002_b0005","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.brainres.2004.06.051","article-title":"Naltrexone attenuates cue-but not drug-induced methamphetamine seeking: A possible mechanism for the dissociation of primary and secondary reward","volume":"1021","author":"Anggadiredja","year":"2004","journal-title":"Brain Research"},{"key":"10.1016\/j.nlm.2015.12.002_b0010","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00213-013-3120-y","article-title":"The reinstatement model of drug relapse: Recent neurobiological findings, emerging research topics, and translational research","volume":"229","author":"Bossert","year":"2013","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.nlm.2015.12.002_b0015","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/j.1460-9568.2012.08021.x","article-title":"Enhanced extinction of cocaine seeking in brain-derived neurotrophic factor Val66Met knock-in mice","volume":"35","author":"Briand","year":"2012","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.nlm.2015.12.002_b0020","doi-asserted-by":"crossref","first-page":"609","DOI":"10.2147\/NDT.S70585","article-title":"Buprenorphine, methadone, and morphine treatment during pregnancy: Behavioral effects on the offspring in rats","volume":"11","author":"Chen","year":"2015","journal-title":"Neuropsychiatric Disease and Treatment"},{"key":"10.1016\/j.nlm.2015.12.002_b0025","doi-asserted-by":"crossref","first-page":"e68371","DOI":"10.1371\/journal.pone.0068371","article-title":"The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice","volume":"8","author":"Chesworth","year":"2013","journal-title":"PloS one"},{"key":"10.1016\/j.nlm.2015.12.002_b0030","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/adb.12055","article-title":"Development of sensitization to methamphetamine in offspring prenatally exposed to morphine, methadone and buprenorphine","volume":"19","author":"Chiang","year":"2014","journal-title":"Addiction Biology"},{"key":"10.1016\/j.nlm.2015.12.002_b0035","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1423-0127-17-46","article-title":"Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine","volume":"17","author":"Chiang","year":"2010","journal-title":"Journal of Biomedical Science"},{"key":"10.1016\/j.nlm.2015.12.002_b0040","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/bjp.2008.51","article-title":"The neurocircuitry of addiction: An overview","volume":"154","author":"Feltenstein","year":"2008","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.nlm.2015.12.002_b0045","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0091-3057(97)00281-5","article-title":"Prenatal morphine enhances morphine-conditioned place preference in adult rats","volume":"58","author":"Gagin","year":"1997","journal-title":"Pharmacology, Biochemistry and Behavior"},{"key":"10.1016\/j.nlm.2015.12.002_b0050","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/npp.2008.140","article-title":"MGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats","volume":"34","author":"Gass","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nlm.2015.12.002_b0055","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.neuroscience.2010.12.021","article-title":"Mediodorsal nucleus of the thalamus is critical for the expression of memory of methamphetamine-produced conditioned place preference in rats","volume":"178","author":"Kuo","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.nlm.2015.12.002_b0060","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0166-4328(00)00239-4","article-title":"Cocaine-induced conditioned place preference. reinstatement by priming injections of cocaine after extinction","volume":"115","author":"Mueller","year":"2000","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.nlm.2015.12.002_b0065","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0378-4274(02)00505-2","article-title":"The impact of intrauterine exposure versus postnatal environment in neurodevelopmental toxicity: Long-term neurobehavioral studies in children at risk for developmental disorders","volume":"140\u2013141","author":"Ornoy","year":"2003","journal-title":"Toxicology Letters"},{"key":"10.1016\/j.nlm.2015.12.002_b0070","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1542\/peds.100.1.79","article-title":"Mortality within the first 2years in infants exposed to cocaine, opiate, or cannabinoid during gestation","volume":"100","author":"Ostrea","year":"1997","journal-title":"Pediatrics"},{"key":"10.1016\/j.nlm.2015.12.002_b0075","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1037\/0735-7044.106.2.274","article-title":"Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning","volume":"106","author":"Phillips","year":"1992","journal-title":"Behavioral Neuroscience"},{"key":"10.1016\/j.nlm.2015.12.002_b0080","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0376-8716(93)90032-L","article-title":"Prenatal exposure to morphine enhances cocaine and heroin self-administration in drug-naive rats","volume":"33","author":"Ramsey","year":"1993","journal-title":"Drug and Alcohol Dependence"},{"key":"10.1016\/j.nlm.2015.12.002_b0085","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1101\/lm.77504","article-title":"Spontaneous recovery","volume":"11","author":"Rescorla","year":"2004","journal-title":"Learning & Memory"},{"key":"10.1016\/j.nlm.2015.12.002_b0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0270(95)00153-0","article-title":"Progressive ratio schedules in drug self-administration studies in rats: A method to evaluate reinforcing efficacy","volume":"66","author":"Richardson","year":"1996","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1016\/j.nlm.2015.12.002_b0095","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.neuropharm.2006.03.022","article-title":"Mid- to late gestational morphine exposure does not alter the rewarding properties of morphine in adult male rats","volume":"51","author":"Riley","year":"2006","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.nlm.2015.12.002_b0100","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1046\/j.1360-0443.2001.9611038.x","article-title":"Incentive-sensitization and addiction","volume":"96","author":"Robinson","year":"2001","journal-title":"Addiction"},{"key":"10.1016\/j.nlm.2015.12.002_b0105","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1146\/annurev.psych.54.101601.145237","article-title":"Addiction","volume":"54","author":"Robinson","year":"2003","journal-title":"Annual Review of Psychology"},{"key":"10.1016\/j.nlm.2015.12.002_b0110","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s00213-008-1187-7","article-title":"Extended methamphetamine self-administration enhances reinstatement of drug seeking and impairs novel object recognition in rats","volume":"199","author":"Rogers","year":"2008","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.nlm.2015.12.002_b0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00213-002-1224-x","article-title":"The reinstatement model of drug relapse: History, methodology and major findings","volume":"168","author":"Shaham","year":"2003","journal-title":"Psychopharmacology (Berl)"},{"issue":"4","key":"10.1016\/j.nlm.2015.12.002_b0120","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/adb.12158","article-title":"Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure","volume":"20","author":"Tan","year":"2015","journal-title":"Addiction Biology"},{"key":"10.1016\/j.nlm.2015.12.002_b0125","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/jnr.21145","article-title":"Role of mu-opioid receptor in modulation of preproenkephalin mRNA expression and opioid and dopamine receptor binding in methamphetamine-sensitized mice","volume":"85","author":"Tien","year":"2007","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.nlm.2015.12.002_b0130","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1369-1600.2007.00070.x","article-title":"Measuring reward with the conditioned place preference (CPP) paradigm: Update of the last decade","volume":"12","author":"Tzschentke","year":"2007","journal-title":"Addiction Biology"},{"key":"10.1016\/j.nlm.2015.12.002_b0135","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/7854_2009_21","article-title":"Sensitization processes in drug addiction","volume":"3","author":"Vanderschuren","year":"2010","journal-title":"Current Topics in Behavioral Neurosciences"},{"key":"10.1016\/j.nlm.2015.12.002_b0140","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/dev.20240","article-title":"Foster mother care but not prenatal morphine exposure enhances cocaine self-administration in young adult male and female rats","volume":"49","author":"Vathy","year":"2007","journal-title":"Developmental Psychobiology"},{"key":"10.1016\/j.nlm.2015.12.002_b0145","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0278-5846(02)00355-X","article-title":"Autoradiographic evidence that prenatal morphine exposure sex-dependently alters mu-opioid receptor densities in brain regions that are involved in the control of drug abuse and other motivated behaviors","volume":"27","author":"Vathy","year":"2003","journal-title":"Progress in Neuro-Psychopharmacology and Biological Psychiatry"},{"issue":"Suppl. 1","key":"10.1016\/j.nlm.2015.12.002_b0150","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1360-0443.2007.01771.x","article-title":"Methamphetamine-induced alterations in monoamine transport: Implications for neurotoxicity, neuroprotection and treatment","volume":"102","author":"Volz","year":"2007","journal-title":"Addiction"},{"key":"10.1016\/j.nlm.2015.12.002_b0155","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/1423-0127-16-106","article-title":"Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring","volume":"16","author":"Wu","year":"2009","journal-title":"Journal of Biomedical Science"},{"key":"10.1016\/j.nlm.2015.12.002_b0160","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1017\/S1461145703003523","article-title":"Functional changes after prenatal opiate exposure related to opiate receptors\u2019 regulated alterations in cholinergic innervation","volume":"6","author":"Yanai","year":"2003","journal-title":"The International Journal of Neuropsychopharmacology"},{"key":"10.1016\/j.nlm.2015.12.002_b0165","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/hipo.10137","article-title":"Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring","volume":"13","author":"Yang","year":"2003","journal-title":"Hippocampus"}],"container-title":["Neurobiology of Learning and Memory"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074742715002324?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074742715002324?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T09:58:19Z","timestamp":1537091899000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074742715002324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":33,"alternative-id":["S1074742715002324"],"URL":"https:\/\/doi.org\/10.1016\/j.nlm.2015.12.002","relation":{},"ISSN":["1074-7427"],"issn-type":[{"value":"1074-7427","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delayed extinction and stronger drug-primed reinstatement of methamphetamine seeking in rats prenatally exposed to morphine","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Learning and Memory","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nlm.2015.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}