{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T22:46:49Z","timestamp":1789944409030,"version":"4.0.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuromuscular Disorders"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.nmd.2005.01.014","type":"journal-article","created":{"date-parts":[[2005,4,19]],"date-time":"2005-04-19T09:53:39Z","timestamp":1113904419000},"page":"427-436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["The effect of respiratory muscle training with CO2 breathing on cellular adaptation of mdx mouse diaphragm"],"prefix":"10.1016","volume":"15","author":[{"given":"Stefan","family":"Matecki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Rivier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Hugon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Koechlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Prefaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Mornet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Ramonatxo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.nmd.2005.01.014_bib1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0092-8674(87)90504-6","article-title":"Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals","volume":"50","author":"Koenig","year":"1987","journal-title":"Cell"},{"issue":"6404","key":"10.1016\/j.nmd.2005.01.014_bib2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/360591a0","article-title":"Primary structure of dystrophin-related protein","volume":"360","author":"Tinsley","year":"1992","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.nmd.2005.01.014_bib3","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/0092-8674(91)90035-W","article-title":"Membrane organization of the dystrophin-glycoprotein complex","volume":"66","author":"Ervasti","year":"1991","journal-title":"Cell"},{"issue":"1\u20132","key":"10.1016\/j.nmd.2005.01.014_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1023\/A:1006812004945","article-title":"The molecular basis of activity-induced muscle injury in Duchenne muscular dystrophy","volume":"179","author":"Petrof","year":"1998","journal-title":"Mol Cell Biochem"},{"issue":"3","key":"10.1016\/j.nmd.2005.01.014_bib5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0960-8966(94)90026-4","article-title":"Computerized respiratory muscle training in children with Duchenne muscular dystrophy","volume":"4","author":"Vilozni","year":"1994","journal-title":"Neuromuscul Disord"},{"issue":"2","key":"10.1016\/j.nmd.2005.01.014_bib6","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1378\/chest.105.2.475","article-title":"Inspiratory muscle training in patients with Duchenne muscular dystrophy","volume":"105","author":"Wanke","year":"1994","journal-title":"Chest"},{"issue":"8","key":"10.1016\/j.nmd.2005.01.014_bib7","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/1097-4598(200008)23:8<1257::AID-MUS15>3.0.CO;2-M","article-title":"Dose-dependent effects of inspiratory muscle training in neuromuscular disorders","volume":"23","author":"Winkler","year":"2000","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.nmd.2005.01.014_bib8","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0960-8966(02)00005-6","article-title":"Dose-dependent effect of individualized respiratory muscle training in children with Duchenne muscular dystrophy","volume":"12","author":"Topin","year":"2002","journal-title":"Neuromuscul Disord"},{"issue":"4912","key":"10.1016\/j.nmd.2005.01.014_bib9","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1126\/science.2662404","article-title":"The molecular basis of muscular dystrophy in the mdx mouse: a point mutation","volume":"244","author":"Sicinski","year":"1989","journal-title":"Science"},{"issue":"6335","key":"10.1016\/j.nmd.2005.01.014_bib10","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/352536a0","article-title":"The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy","volume":"352","author":"Stedman","year":"1991","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.nmd.2005.01.014_bib11","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0022-510X(94)00276-T","article-title":"mdx mice show progressive weakness and muscle deterioration with age","volume":"129","author":"Pastoret","year":"1995","journal-title":"J Neurol Sci"},{"issue":"8","key":"10.1016\/j.nmd.2005.01.014_bib12","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.1073\/pnas.90.8.3710","article-title":"Dystrophin protects the sarcolemma from stresses developed during muscle contraction","volume":"90","author":"Petrof","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"10.1016\/j.nmd.2005.01.014_bib13","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1152\/jappl.1996.80.3.734","article-title":"Exercise and clenbuterol as strategies to decrease the progression of muscular dystrophy in mdx mice","volume":"80","author":"Dupont-Versteegden","year":"1996","journal-title":"J Appl Physiol"},{"issue":"2","key":"10.1016\/j.nmd.2005.01.014_bib14","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1152\/jappl.1996.80.2.670","article-title":"Beneficial effects of voluntary wheel running on the properties of dystrophic mouse muscle","volume":"80","author":"Hayes","year":"1996","journal-title":"J Appl Physiol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib15","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0272-5231(21)00959-X","article-title":"Respiratory dysfunction in muscular dystrophy and other myopathies","volume":"15","author":"Lynn","year":"1994","journal-title":"Clin Chest Med"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib16","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1152\/jappl.1994.77.4.1736","article-title":"Voluntary exercise decreases progression of muscular dystrophy in diaphragm of mdx mice","volume":"77","author":"Dupont-Versteegden","year":"1994","journal-title":"J Appl Physiol"},{"issue":"6607","key":"10.1016\/j.nmd.2005.01.014_bib17","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/384349a0","article-title":"Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene","volume":"384","author":"Tinsley","year":"1996","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib18","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/ng0598-79","article-title":"Skeletal muscle-specific expression of a utrophin transgene rescues utrophin\u2013dystrophin deficient mice","volume":"19","author":"Rafael","year":"1998","journal-title":"Nat Genet"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib19","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1006\/jmbi.2000.4480","article-title":"Molecular, genetic and physiological characterisation of dystrobrevin-like (dyb-1) mutants of Caenorhabditis elegans","volume":"307","author":"Gieseler","year":"2001","journal-title":"J Mol Biol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib20","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0960-8966(01)00330-3","article-title":"Overexpression of dystrobrevin delays locomotion defects and muscle degeneration in a dystrophin-deficient Caenorhabditis elegans","volume":"12","author":"Gieseler","year":"2002","journal-title":"Neuromuscul Disord"},{"issue":"2","key":"10.1016\/j.nmd.2005.01.014_bib21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/physrev.00028.2001","article-title":"Function and genetics of dystrophin and dystrophin-related proteins in muscle","volume":"82","author":"Blake","year":"2002","journal-title":"Physiol Rev"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib22","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0034-5687(78)90103-2","article-title":"A theoretical analysis of the barometric method for measurement of tidal volume","volume":"32","author":"Epstein","year":"1978","journal-title":"Respir Physiol"},{"issue":"3 Pt 1","key":"10.1016\/j.nmd.2005.01.014_bib23","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1164\/ajrccm.156.3.9606031","article-title":"Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography","volume":"156","author":"Hamelmann","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.nmd.2005.01.014_bib24","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1165\/ajrcmb.13.5.7576685","article-title":"Efficiency and functional consequences of adenovirus-mediated in vivo gene transfer to normal and dystrophic (mdx) mouse diaphragm","volume":"13","author":"Petrof","year":"1995","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.nmd.2005.01.014_bib25","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.nmd.2005.01.014_bib26","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/B978-0-12-152805-8.50013-7","article-title":"The citrate enzymes: their structures, mechanisms, and biological functions","volume":"5","author":"Srere","year":"1972","journal-title":"Curr Top Cell Regul"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib27","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1161\/01.CIR.90.1.369","article-title":"Utrophin localization in normal and dystrophin-deficient heart","volume":"90","author":"Pons","year":"1994","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1750-3639.1996.tb00781.x","article-title":"Utrophin: a structural and functional comparison to dystrophin","volume":"6","author":"Blake","year":"1996","journal-title":"Brain Pathol"},{"issue":"19","key":"10.1016\/j.nmd.2005.01.014_bib29","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1056\/NEJM198705073161906","article-title":"Practical problems in the respiratory care of patients with muscular dystrophy","volume":"316","author":"Smith","year":"1987","journal-title":"N Engl J Med"},{"issue":"5\u20136","key":"10.1016\/j.nmd.2005.01.014_bib30","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0960-8966(93)90098-5","article-title":"Morphometric analysis of mdx diaphragm muscle fibres. Comparison with hindlimb muscles","volume":"3","author":"Louboutin","year":"1993","journal-title":"Neuromuscul Disord"},{"issue":"10","key":"10.1016\/j.nmd.2005.01.014_bib31","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1002\/mus.880181011","article-title":"Age-related differences in regeneration of dystrophic (mdx) and normal muscle in the mouse","volume":"18","author":"Pastoret","year":"1995","journal-title":"Muscle Nerve"},{"issue":"3","key":"10.1016\/j.nmd.2005.01.014_bib32","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/mus.10431","article-title":"Ventilatory dysfunction in mdx mice: impact of tumor necrosis factor-alpha deletion","volume":"28","author":"Gosselin","year":"2003","journal-title":"Muscle Nerve"},{"issue":"2","key":"10.1016\/j.nmd.2005.01.014_bib33","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1378\/chest.119.2.565","article-title":"Size and composition changes in diaphragmatic fibers in rats exposed to chronic hypercapnia","volume":"119","author":"Kumagai","year":"2001","journal-title":"Chest"},{"issue":"1336","key":"10.1016\/j.nmd.2005.01.014_bib34","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1098\/rspb.1993.0077","article-title":"The effects of endurance exercise on dystrophic mdx mice. I. Contractile and histochemical properties of intact muscles","volume":"253","author":"Hayes","year":"1993","journal-title":"Proc R Soc Lond B Biol Sci"},{"issue":"Suppl. 1","key":"10.1016\/j.nmd.2005.01.014_bib35","doi-asserted-by":"crossref","first-page":"S110","DOI":"10.1016\/S0960-8966(02)00091-3","article-title":"Dystrobrevin dynamics in muscle-cell signalling: a possible target for therapeutic intervention in Duchenne muscular dystrophy?","volume":"12","author":"Blake","year":"2002","journal-title":"Neuromuscul Disord"},{"issue":"6","key":"10.1016\/j.nmd.2005.01.014_bib36","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1177\/153537020422900608","article-title":"Altered activity of signaling pathways in diaphragm and tibialis anterior muscle of dystrophic mice","volume":"229","author":"Lang","year":"2004","journal-title":"Exp Biol Med (Maywood)"},{"issue":"5","key":"10.1016\/j.nmd.2005.01.014_bib37","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1083\/jcb.142.5.1269","article-title":"Differential membrane localization and intermolecular associations of alpha-dystrobrevin isoforms in skeletal muscle","volume":"142","author":"Peters","year":"1998","journal-title":"J Cell Biol"},{"issue":"10","key":"10.1016\/j.nmd.2005.01.014_bib38","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1002\/pmic.200300561","article-title":"Proteomic analysis of mdx skeletal muscle: great reduction of adenylate kinase 1 expression and enzymatic activity","volume":"3","author":"Ge","year":"2003","journal-title":"Proteomics"},{"issue":"5","key":"10.1016\/j.nmd.2005.01.014_bib39","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1365-2990.1997.tb01314.x","article-title":"The abnormal expression of utrophin in Duchenne and Becker muscular dystrophy is age related","volume":"23","author":"Taylor","year":"1997","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib40","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1152\/jappl.1998.84.1.318","article-title":"Muscle fiber architecture of the dog diaphragm","volume":"84","author":"Boriek","year":"1998","journal-title":"J Appl Physiol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib41","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/12034","article-title":"Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies","volume":"1","author":"Grady","year":"1999","journal-title":"Nat Cell Biol"},{"issue":"7","key":"10.1016\/j.nmd.2005.01.014_bib42","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1093\/hmg\/6.7.1185","article-title":"Dystrobrevin deficiency at the sarcolemma of patients with muscular dystrophy","volume":"6","author":"Metzinger","year":"1997","journal-title":"Hum Mol Genet"},{"issue":"6","key":"10.1016\/j.nmd.2005.01.014_bib43","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1083\/jcb.150.6.1399","article-title":"Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain","volume":"150","author":"Crawford","year":"2000","journal-title":"J Cell Biol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib44","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0092-8674(00)80533-4","article-title":"Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy","volume":"90","author":"Grady","year":"1997","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib45","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1165\/rcmb.2002-0126OC","article-title":"Hypercapnic acidosis attenuates endotoxin-induced nuclear factor-[kappa]B activation","volume":"29","author":"Takeshita","year":"2003","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib46","doi-asserted-by":"crossref","first-page":"R1165","DOI":"10.1152\/ajpregu.2000.279.4.R1165","article-title":"NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes","volume":"279","author":"Li","year":"2000","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4","key":"10.1016\/j.nmd.2005.01.014_bib47","doi-asserted-by":"crossref","first-page":"335","DOI":"10.33549\/physiolres.930206","article-title":"The role of carbon dioxide in free radical reactions of the organism","volume":"51","author":"Vesela","year":"2002","journal-title":"Physiol Res"},{"issue":"1","key":"10.1016\/j.nmd.2005.01.014_bib48","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0960-8966(97)00124-7","article-title":"Muscle cells from mdx mice have an increased susceptibility to oxidative stress","volume":"8","author":"Rando","year":"1998","journal-title":"Neuromuscul Disord"}],"container-title":["Neuromuscular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896605000623?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896605000623?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:53:46Z","timestamp":1760774026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960896605000623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0960896605000623"],"URL":"https:\/\/doi.org\/10.1016\/j.nmd.2005.01.014","relation":{},"ISSN":["0960-8966"],"issn-type":[{"value":"0960-8966","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of respiratory muscle training with CO2 breathing on cellular adaptation of mdx mouse diaphragm","name":"articletitle","label":"Article Title"},{"value":"Neuromuscular Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nmd.2005.01.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}