{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T08:08:22Z","timestamp":1770106102816,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuromuscular Disorders"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.nmd.2009.10.003","type":"journal-article","created":{"date-parts":[[2009,11,13]],"date-time":"2009-11-13T05:06:59Z","timestamp":1258088819000},"page":"21-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Attenuation of adverse cardiac effects in prednisolone-treated \u03b4-sarcoglycan-deficient mice by mineralocorticoid-receptor-antagonism"],"prefix":"10.1016","volume":"20","author":[{"given":"Ralf","family":"Bauer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Blain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Greally","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanns","family":"Lochm\u00fcller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Bushby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy A.","family":"MacGowan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Straub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nmd.2009.10.003_bib1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/hmg\/11.3.263","article-title":"A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice","volume":"11","author":"Porter","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.nmd.2009.10.003_bib2","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.nmd.2004.05.006","article-title":"Report on the 124th ENMC International Workshop. Treatment of Duchenne muscular dystrophy; defining the gold standards of management in the use of corticosteroids. 2\u20134 April 2004, Naarden, The Netherlands","volume":"14","author":"Bushby","year":"2004","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2009.10.003_bib3","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0002-9149(02)03429-X","article-title":"Effects of deflazacort on left ventricular function in patients with Duchenne muscular dystrophy","volume":"91","author":"Silversides","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib4","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1007\/s00246-005-0909-4","article-title":"Steroid therapy and cardiac function in Duchenne muscular dystrophy","volume":"26","author":"Markham","year":"2005","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib5","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1093\/cvr\/cvn131","article-title":"Steroid treatment causes deterioration of myocardial function in the \u03b4-sarcoglycan-deficient mouse model for dilated cardiomyopathy","volume":"79","author":"Bauer","year":"2008","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.nmd.2009.10.003_bib6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.tcm.2006.12.002","article-title":"Consequences of disrupting the dystrophin\u2013sarcoglycan complex in cardiac and skeletal myopathy","volume":"17","author":"Heydemann","year":"2007","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.nmd.2009.10.003_bib7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/mus.20349","article-title":"Molecular and cell biology of the sarcoglycan complex","volume":"32","author":"Ozawa","year":"2005","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.nmd.2009.10.003_bib8","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1161\/01.RES.0000126574.61061.25","article-title":"The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma","volume":"94","author":"Lapidos","year":"2004","journal-title":"Circ Res"},{"key":"10.1016\/j.nmd.2009.10.003_bib9","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1096\/fj.01-0030fje","article-title":"Dystrophin-deficient cardiomyocytes are abnormally vulnerable to mechanical stress-induced contractile failure and injury","volume":"15","author":"Danialou","year":"2001","journal-title":"FASEB J"},{"key":"10.1016\/j.nmd.2009.10.003_bib10","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1050-1738(03)00101-4","article-title":"Sarcoglycans in vascular smooth and striated muscle","volume":"13","author":"Wheeler","year":"2003","journal-title":"Trends Cardiovasc Med"},{"key":"10.1016\/j.nmd.2009.10.003_bib11","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0092-8674(00)81975-3","article-title":"Disruption of the sarcoglycan\u2013sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy","volume":"98","author":"Coral-Vazquez","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.nmd.2009.10.003_bib12","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1242\/jcs.113.14.2535","article-title":"Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin\u2013glycoprotein complex","volume":"113","author":"Hack","year":"2000","journal-title":"J Cell Sci"},{"key":"10.1016\/j.nmd.2009.10.003_bib13","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1530\/EJE-07-0455","article-title":"Glucocorticoids and cardiovascular disease","volume":"157","author":"Walker","year":"2007","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.nmd.2009.10.003_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1161\/01.RES.0000080521.15238.E5","article-title":"Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure","volume":"93","author":"Qin","year":"2003","journal-title":"Circ Res"},{"key":"10.1016\/j.nmd.2009.10.003_bib15","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1161\/01.HYP.0000203772.78696.67","article-title":"Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats","volume":"47","author":"Nagata","year":"2006","journal-title":"Hypertension"},{"key":"10.1016\/j.nmd.2009.10.003_bib16","doi-asserted-by":"crossref","first-page":"5901","DOI":"10.1210\/en.2006-0658","article-title":"The role of the glucocorticoid receptor in mineralocorticoid\/salt-mediated cardiac fibrosis","volume":"147","author":"Rickard","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.nmd.2009.10.003_bib17","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jsbmb.2004.12.010","article-title":"RALES, EPHESUS and redox","volume":"93","author":"Funder","year":"2005","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.nmd.2009.10.003_bib18","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized aldactone evaluation study investigators","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nmd.2009.10.003_bib19","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1161\/01.CIR.0000068340.96506.0F","volume":"107","author":"Hayashi","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.nmd.2009.10.003_bib20","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1161\/01.CIR.0000163562.82134.8E","article-title":"Persistent cardiac aldosterone synthesis in angiotensin II type 1A receptor-knockout mice after myocardial infarction","volume":"111","author":"Katada","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.nmd.2009.10.003_bib21","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1152\/japplphysiol.00959.2004","article-title":"In vivo alpha-adrenergic responses and troponin I phosphorylation: anesthesia interactions","volume":"98","author":"MacGowan","year":"2005","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib22","doi-asserted-by":"crossref","first-page":"H755","DOI":"10.1152\/ajpheart.2001.281.2.H755","article-title":"Hypertonic saline method accurately determines parallel conductance for dual-field conductance catheter","volume":"281","author":"Steendijk","year":"2001","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1161\/01.RES.35.1.117","article-title":"Instantaneous pressure-volume relationships and their ratio in the excised, supported canine left ventricle","volume":"35","author":"Suga","year":"1974","journal-title":"Circ Res"},{"key":"10.1016\/j.nmd.2009.10.003_bib24","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1161\/01.CIR.71.5.994","article-title":"Linearity of the Frank\u2013Starling relationship in the intact heart: the concept of preload recruitable stroke work","volume":"71","author":"Glower","year":"1985","journal-title":"Circulation"},{"key":"10.1016\/j.nmd.2009.10.003_bib25","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1046\/j.0021-8782.2001.00008.x","article-title":"Evans Blue Dye as an in vivo marker of myofibre damage: optimising parameters for detecting initial myofibre membrane permeability","volume":"200","author":"Hamer","year":"2002","journal-title":"J Anat"},{"key":"10.1016\/j.nmd.2009.10.003_bib26","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1093\/nar\/30.9.e36","article-title":"Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR","volume":"30","author":"Pfaffl","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.nmd.2009.10.003_bib27","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0960-8966(02)00180-3","article-title":"High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy","volume":"12","author":"Connolly","year":"2002","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2009.10.003_bib28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1161\/01.HYP.0000025879.29822.24","article-title":"Rapid effects of aldosterone and spironolactone in the isolated working rat heart","volume":"40","author":"Barbato","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.nmd.2009.10.003_bib29","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1517\/13543784.10.5.943","article-title":"The spironolactone renaissance","volume":"10","author":"Doggrell","year":"2001","journal-title":"Expert Opin Investig Drugs"},{"key":"10.1016\/j.nmd.2009.10.003_bib30","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.cardfail.2006.01.002","article-title":"Aldosterone antagonism improves endothelial-dependent vasorelaxation in heart failure via upregulation of endothelial nitric oxide synthase production","volume":"12","author":"Thai","year":"2006","journal-title":"J Card Fail"},{"key":"10.1016\/j.nmd.2009.10.003_bib31","doi-asserted-by":"crossref","first-page":"H1364","DOI":"10.1152\/ajpheart.00355.2006","article-title":"Spatial disruption and enhanced degradation of collagen with the transition from compensated ventricular hypertrophy to symptomatic congestive heart failure","volume":"292","author":"Graham","year":"2007","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib32","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0735-1097(94)00557-7","article-title":"Dilated cardiomyopathy is associated with an increase in the type I\/type III collagen ration: a quantitative assessment","volume":"25","author":"Marijianowski","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nmd.2009.10.003_bib33","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1161\/01.RES.82.4.519","article-title":"Murine cardiac function: a cautionary tail","volume":"82","author":"Kass","year":"1998","journal-title":"Circ Res"}],"container-title":["Neuromuscular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896609006543?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896609006543?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:57:23Z","timestamp":1760774243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960896609006543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0960896609006543"],"URL":"https:\/\/doi.org\/10.1016\/j.nmd.2009.10.003","relation":{},"ISSN":["0960-8966"],"issn-type":[{"value":"0960-8966","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Attenuation of adverse cardiac effects in prednisolone-treated \u03b4-sarcoglycan-deficient mice by mineralocorticoid-receptor-antagonism","name":"articletitle","label":"Article Title"},{"value":"Neuromuscular Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nmd.2009.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}