{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:11:50Z","timestamp":1785111110095,"version":"3.55.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100016003","name":"Istanbul \u00dcniversitesi-Cerrahpasa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuromuscular Disorders"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.nmd.2020.09.001","type":"journal-article","created":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T07:14:51Z","timestamp":1599376491000},"page":"845-850","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["The effects of non-invasive mechanical ventilation on cardiac autonomic dysfunction in spinal muscular atrophy"],"prefix":"10.1016","volume":"30","author":[{"given":"Gulcin Benbir","family":"Senel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Burcu","family":"Arkali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sema","family":"Saltik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cengiz","family":"Yalcinkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derya","family":"Karadeniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nmd.2020.09.001_bib0001","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1474-4422(12)70061-3","article-title":"Childhood spinal muscular atrophy: controversies and challenges","volume":"11","author":"Mercuri","year":"2012","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0002","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.nmd.2017.11.004","article-title":"Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics","volume":"28","author":"Finkel","year":"2018","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2020.09.001_bib0003","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.sleep.2014.05.029","article-title":"Sleep architecture in infants with spinal muscular atrophy type 1","volume":"15","author":"Verrillo","year":"2014","journal-title":"Sleep Med"},{"key":"10.1016\/j.nmd.2020.09.001_bib0004","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1177\/0883073818767170","article-title":"Electrocardiographic evaluation in patients with spinal muscular atrophy: a case-control study","volume":"33","author":"Falsaperla","year":"2018","journal-title":"J Child Neurol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/PHM.0b013e31804b1d66","article-title":"Medical considerations of long-term survival of Werdnig-Hoffmann disease","volume":"86","author":"Bach","year":"2007","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.nmd.2020.09.001_bib0006","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13023-017-0613-5","article-title":"Cardiac pathology in spinal muscular atrophy: a systematic review","volume":"12","author":"Wijngaarde","year":"2017","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.nmd.2020.09.001_bib0007","doi-asserted-by":"crossref","first-page":"H469","DOI":"10.1152\/ajpheart.00507.2016","article-title":"The role of sympathetic and vagal cardiac control on complexity of heart rate dynamics","volume":"312","author":"Silva","year":"2017","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0008","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ijcard.2009.09.543","article-title":"The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors","volume":"141","author":"Thayer","year":"2010","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0009","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1046\/j.1542-474X.2003.08209.x","article-title":"Heart rate variability in obstructive sleep apnea: a prospective study and frequency domain analysis","volume":"8","author":"Gula","year":"2003","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0010","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11325-014-1029-2","article-title":"Heart rate variability is augmented in patients with positional obstructive sleep apnea, but only supine LF\/HF index correlates with its severity","volume":"19","author":"Flevari","year":"2015","journal-title":"Sleep Breath"},{"key":"10.1016\/j.nmd.2020.09.001_bib0011","first-page":"18","article-title":"The role of sleep diagnostics and non-invasive ventilation in children with spinal muscular atrophy","volume":"28","author":"Grychtol","year":"2018","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.nmd.2020.09.001_bib0012","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/resp.12330","article-title":"Neuromuscular disease and respiratory physiology in children: putting lung function into perspective","volume":"19","author":"Fauroux","year":"2014","journal-title":"Respirology"},{"key":"10.1016\/j.nmd.2020.09.001_bib0013","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.nmd.2004.09.004","article-title":"Sleep disordered breathing in spinal muscular atrophy","volume":"14","author":"Mellies","year":"2004","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2020.09.001_bib0014","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1136\/thorax.57.8.724","article-title":"Patterns and predictors of sleep disordered breathing in primary myopathies","volume":"57","author":"Ragette","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.nmd.2020.09.001_bib0015","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3389\/fmed.2016.00040","article-title":"Prognostic value of initial assessment of residual hypoventilation using nocturnal capnography in mechanically ventilated neuromuscular patients: a 5-year follow-up study","volume":"3","author":"Ogna","year":"2016","journal-title":"Front Med"},{"key":"10.1016\/j.nmd.2020.09.001_bib0016","doi-asserted-by":"crossref","first-page":"226","DOI":"10.3346\/jkms.2008.23.2.226","article-title":"Correlation between the severity of obstructive sleep apnea and heart rate variability indices","volume":"23","author":"Park","year":"2008","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.nmd.2020.09.001_bib0017","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-2281.1999.00163.x","article-title":"Reduced cardiac sympathetic autonomic tone after long-term nasal continuous positive airway pressure in obstructive sleep apnoea syndrome","volume":"19","author":"Roche","year":"1999","journal-title":"Clin Physiol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0018","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.arbres.2015.03.008","article-title":"Long-term impact of continuous positive airway pressure therapy on arrhythmia and heart rate variability in patients with sleep apnea","volume":"52","author":"Grau","year":"2016","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0019","series-title":"International classification of sleep disorders","year":"2014"},{"key":"10.1016\/j.nmd.2020.09.001_bib0020","series-title":"The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications","article-title":"Harding SM; for the American academy of sleep medicine","author":"Berry","year":"2018"},{"key":"10.1016\/j.nmd.2020.09.001_bib0021","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1152\/japplphysiol.01087.2002","article-title":"Noninvasive measurement of the tension-time index in children with neuromuscular disease","volume":"95","author":"Mulreany","year":"2003","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.nmd.2020.09.001_bib0022","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.chest.2017.03.023","article-title":"Sleep-disordered breathing in neuromuscular disease: diagnostic and therapeutic challenges","volume":"152","author":"Aboussouan","year":"2017","journal-title":"Chest"},{"key":"10.1016\/j.nmd.2020.09.001_bib0023","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1203\/PDR.0b013e318179951d","article-title":"Relationship between functional residual capacity and oxygen desaturation during short central apneic events during sleep in \u2018\u2018late preterm\u201d infants","volume":"64","author":"Tourneux","year":"2008","journal-title":"Pediatr Res"},{"key":"10.1016\/j.nmd.2020.09.001_bib0024","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1097\/01.phm.0000176362.24957.77","article-title":"Sleepdisordered breathing in spinal muscular atrophy types 1 and 2","volume":"84","author":"Testa","year":"2005","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.nmd.2020.09.001_bib0025","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/PHM.0b013e31802ef774","article-title":"Noninvasive ventilation in children with spinal muscular atrophy types 1 and 2","volume":"86","author":"Petrone","year":"2007","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.nmd.2020.09.001_bib0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sleep.2015.12.015","article-title":"Sleep architecture in children with spinal muscular atrophy type 2","volume":"20","author":"Verrillo","year":"2016","journal-title":"Sleep Med"},{"issue":"Suppl 1","key":"10.1016\/j.nmd.2020.09.001_bib0027","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/thoraxjnl-2012-201964","article-title":"British Thoracic Society guideline for respiratory management of children with neuromuscular weakness","volume":"67","author":"Hull","year":"2012","journal-title":"Thorax"},{"key":"10.1016\/j.nmd.2020.09.001_bib0028","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.nmd.2015.09.009","article-title":"1st Italian SMA family association consensus meeting: management and recommendations for respiratory involvement in spinal muscular atrophy (SMA) types I-III, Rome, Italy, 30\u201331 January 2015","volume":"25","author":"Sansone","year":"2015","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2020.09.001_bib0029","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.sleep.2019.03.005","article-title":"Effects of long-term non-invasive ventilation on sleep structure in children with Spinal Muscular Atrophy type 2","volume":"58","author":"Verrillo","year":"2019","journal-title":"Sleep Med"},{"key":"10.1016\/j.nmd.2020.09.001_bib0030","article-title":"Nocturnal mechanical ventilation for chronic hypoventilation in patients with neuromuscular and chest wall disorders","volume":"12","author":"Annane","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.nmd.2020.09.001_bib0031","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S0960-8966(03)00162-7","article-title":"The Duchenne muscular dystrophy population in Denmark, 1977\u20132001: prevalence, incidence and survival in relation to the introduction of ventilator use","volume":"13","author":"Jeppesen","year":"2003","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2020.09.001_bib0032","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1136\/thx.2004.037424","article-title":"Randomised controlled trial of non-invasive ventilation (NIV) for nocturnal hypoventilation in neuromuscular and chest wall disease patients with daytime normocapnia","volume":"60","author":"Ward","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.nmd.2020.09.001_bib0033","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.hrtlng.2018.05.019","article-title":"The impact of continuous positive airway pressure on heart rate variability in obstructive sleep apnea patients during sleep: a meta-analysis","volume":"47","author":"Guo","year":"2018","journal-title":"Heart Lung"},{"key":"10.1016\/j.nmd.2020.09.001_bib0034","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1183\/09031936.00026608","article-title":"CPAP and measures of cardiovascular risk in males with OSAS","volume":"32","author":"Kohler","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.nmd.2020.09.001_bib0035","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1183\/09031936.95.08020222","article-title":"Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: cardiovascular implications","volume":"8","author":"Hedner","year":"1995","journal-title":"Eur Respir J"},{"issue":"Suppl. 4","key":"10.1016\/j.nmd.2020.09.001_bib0036","doi-asserted-by":"crossref","first-page":"S245","DOI":"10.1542\/peds.2008-2952K","article-title":"Special considerations in the respiratory management of spinal muscular atrophy","author":"Schroth","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.nmd.2020.09.001_bib0037","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.nmd.2015.04.009","article-title":"209th ENMC international workshop: outcome measures and clinical trial readiness in spinal muscular atrophy 7\u20139 November 2014, Heemskerk, The Netherlands","volume":"25","author":"Finkel","year":"2015","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.nmd.2020.09.001_bib0038","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1086\/338627","article-title":"Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy","volume":"70","author":"Feldkotter","year":"2002","journal-title":"Am J Hum Genet"}],"container-title":["Neuromuscular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896620305654?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960896620305654?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T08:09:56Z","timestamp":1760774996000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960896620305654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S0960896620305654"],"URL":"https:\/\/doi.org\/10.1016\/j.nmd.2020.09.001","relation":{},"ISSN":["0960-8966"],"issn-type":[{"value":"0960-8966","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of non-invasive mechanical ventilation on cardiac autonomic dysfunction in spinal muscular atrophy","name":"articletitle","label":"Article Title"},{"value":"Neuromuscular Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nmd.2020.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}