{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T14:41:48Z","timestamp":1782139308769,"version":"3.54.5"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropeptides"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.npep.2004.12.005","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T13:46:55Z","timestamp":1107352015000},"page":"233-237","source":"Crossref","is-referenced-by-count":29,"title":["Galanin plasticity in the cholinergic basal forebrain in Alzheimer\u2019s disease and transgenic mice"],"prefix":"10.1016","volume":"39","author":[{"given":"Elliott J.","family":"Mufson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott E.","family":"Counts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia E.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Binder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.npep.2004.12.005_bib1","doi-asserted-by":"crossref","first-page":"11287","DOI":"10.1073\/pnas.90.23.11287","article-title":"Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes","volume":"90","author":"Bartfai","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.npep.2004.12.005_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/cne.903360103","article-title":"Galanin immunoreactivity within the primate basal forebrain: evolutionary change between monkeys and apes","volume":"336","author":"Benzing","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.npep.2004.12.005_bib3","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1750-3639.1997.tb01058.x","article-title":"A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer\u2019s disease","volume":"7","author":"Bowser","year":"1997","journal-title":"Brain Pathol."},{"key":"10.1016\/j.npep.2004.12.005_bib4","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1042\/bj2790831","article-title":"A68 proteins in Alzheimer\u2019s disease are composed of several tau isoforms in a phosophorylated state which affect their electrophoretic mobilities","volume":"279","author":"Brion","year":"1991","journal-title":"Biochem. J."},{"key":"10.1016\/j.npep.2004.12.005_bib5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/cne.902730409","article-title":"Galanin hyperinnervates surviving neurons of the human basal nucleus of Meynert in dementias of Alzheimer\u2019s and Parkinson\u2019s disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia","volume":"273","author":"Chan-Palay","year":"1988","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.npep.2004.12.005_bib6","unstructured":"Counts, S.E., Chen, E.Y., Ikonomovic, M.D., Wuu, J., Cochran, E.J., Bennett, D.A., Levey, A.I., Kordower, J.H., DeKosky, S.T., Mufson, E.J., 2002. Galanin plasticity within the nucleus basalis in people with mild cognitive impairment. Neurosci. Abstr"},{"key":"10.1016\/j.npep.2004.12.005_bib7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1527-3458.2001.tb00210.x","article-title":"Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer\u2019s disease","volume":"7","author":"Counts","year":"2001","journal-title":"CNS Rev. (peer reviewed)"},{"key":"10.1016\/j.npep.2004.12.005_bib8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1124\/mi.3.3.137","article-title":"Galanin plasticity in Alzheimer\u2019s disease","volume":"3","author":"Counts","year":"2003","journal-title":"Mol. Intervention"},{"key":"10.1016\/j.npep.2004.12.005_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1054\/npep.2002.0891","article-title":"Galanin overexpressing transgenic mice","volume":"36","author":"Crawley","year":"2002","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2004.12.005_bib10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0306-4522(00)00261-X","article-title":"Neuropeptides in hippocampus and cortex in transgenic mice overexpressing V717F \u03b2-amyloid precursor protein-initial observations","volume":"100","author":"Diez","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.npep.2004.12.005_bib11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0006-8993(91)91409-T","article-title":"Galanin inhibits the potassium-evoked release of acetylcholine and the muscarinic receptor-mediated stimulation of phosphoinositide turnover in slices of monkey hippocampus","volume":"568","author":"Fisone","year":"1991","journal-title":"Brain. Res."},{"key":"10.1016\/j.npep.2004.12.005_bib12","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3233\/JAD-2003-5201","article-title":"Conformational changes and truncation of tau protein during tangle evolution in Alzheimer\u2019s disease","volume":"5","author":"Garc\u00eda-Sierra","year":"2003","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.npep.2004.12.005_bib13","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1046\/j.1471-4159.2001.00346.x","article-title":"Tau-66: evidence for a novel tau conformation in Alzheimer\u2019s disease","volume":"77","author":"Ghoshal","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.npep.2004.12.005_bib14","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/(SICI)1096-9861(19990906)411:4<693::AID-CNE13>3.0.CO;2-D","article-title":"Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer\u2019s disease","volume":"411","author":"Gilmore","year":"1999","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"10.1016\/j.npep.2004.12.005_bib15","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1055\/s-2007-978748","article-title":"Galanin and NPY, two peptides with multiple putative roles in the nervous system","volume":"31","author":"Hokfelt","year":"1999","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.npep.2004.12.005_bib16","doi-asserted-by":"crossref","first-page":"4044","DOI":"10.1073\/pnas.83.11.4044","article-title":"Microtubule-associated protein tau a major antigenic component of paired helical filaments in Alzheimer\u2019s disease","volume":"83","author":"Kosik","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.npep.2004.12.005_bib17","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0304-3940(89)90384-4","article-title":"Galanin-like immunoreactivity is present in human substantia innominata and in senile plaques in Alzheimer\u2019s disease","volume":"98","author":"Kowall","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.npep.2004.12.005_bib18","doi-asserted-by":"crossref","first-page":"9785","DOI":"10.1523\/JNEUROSCI.22-22-09785.2002","article-title":"Evidence that synaptically released \u03b2-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice","volume":"22","author":"Lazarov","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.npep.2004.12.005_bib19","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/cne.902480404","article-title":"Distribution of galanin like immunoreactivity in the rat central nervous system","volume":"248","author":"Melander","year":"1986","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.npep.2004.12.005_bib20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/cne.902140206","article-title":"Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata) and hypothalamus in the rhesus monkey","volume":"214","author":"Mesulam","year":"1983","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.npep.2004.12.005_bib21","first-page":"237","article-title":"Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer\u2019s disease and Down\u2019s syndrome","volume":"4","author":"Mufson","year":"1993","journal-title":"Dementia"},{"key":"10.1016\/j.npep.2004.12.005_bib22","doi-asserted-by":"crossref","unstructured":"Mufson, E.J., Kordower, J.H., (Eds.), 2000. Cholinergic Basal Forebrain Systems in the Primate Central Nervous System: Anatomy, Connectivity, Neurochemistry, Aging, Dementia and Experimental Therapeutics. In: Hof, P.R., Moobs C.V. (Eds.), Functional Neurobiology of Aging. Academic Press, San Diego, pp. 243\u2013276","DOI":"10.1016\/B978-012351830-9\/50021-4"},{"key":"10.1016\/j.npep.2004.12.005_bib23","unstructured":"Perez, S.E., Lazarov, O., Rodriguez, V., Sisodia, S.S., Mufson, E.J., 2004. Axonal dystrophy in cholinergic, galaninergic and dopaminergic projection systems in APPswe\/PS1\u0394 E9 transgenic mice. In: World Conference on Alzheimer\u2019s Disease, Philadelphia (Abstr.)"},{"key":"10.1016\/j.npep.2004.12.005_bib24","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1046\/j.1471-4159.2000.741185.x","article-title":"Reduction in trkA immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down\u2019s syndrome","volume":"74","author":"Sendera","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.npep.2004.12.005_bib25","doi-asserted-by":"crossref","first-page":"4184","DOI":"10.1073\/pnas.061445598","article-title":"Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer\u2019s Disease","volume":"98","author":"Steiner","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.npep.2004.12.005_bib26","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/0014-5793(83)80033-7","article-title":"Galanin \u2013 a novel biologically active peptide from porcine intestine","volume":"164","author":"Tatemoto","year":"1983","journal-title":"FEBS Lett."},{"key":"10.1016\/j.npep.2004.12.005_bib27","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0143-4179(02)00111-7","article-title":"Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance","volume":"36","author":"Wrenn","year":"2002","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2004.12.005_bib28","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1054\/npep.2002.0888","article-title":"Targeted disruption of galanin: new insights from knock-out studies","volume":"36","author":"Wynick","year":"2002","journal-title":"Neuropeptides"},{"issue":"3\u20134","key":"10.1016\/j.npep.2004.12.005_bib29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1054\/npep.2000.0820","article-title":"Galanin and spinal nociceptive mechanisms: recent advances and therapeutic implications","volume":"34","author":"Xu","year":"2000","journal-title":"Neuropeptides"}],"container-title":["Neuropeptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417904001386?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417904001386?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,5]],"date-time":"2020-04-05T15:15:24Z","timestamp":1586099724000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143417904001386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0143417904001386"],"URL":"https:\/\/doi.org\/10.1016\/j.npep.2004.12.005","relation":{},"ISSN":["0143-4179"],"issn-type":[{"value":"0143-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}