{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:36:14Z","timestamp":1778841374462,"version":"3.51.4"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Vereinigung zur F\u00f6rderung der p\u00e4diatrischen Forschung und Fortbildung Salzburg"},{"name":"Mitochondrial European Educational Training"},{"name":"ITN MARIE CURIE PEOPLE","award":["317433"],"award-info":[{"award-number":["317433"]}]},{"DOI":"10.13039\/501100004955","name":"Austrian Research Promotion Agency","doi-asserted-by":"publisher","award":["822782\/THERAPEP"],"award-info":[{"award-number":["822782\/THERAPEP"]}],"id":[{"id":"10.13039\/501100004955","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003549","name":"OTKA","doi-asserted-by":"publisher","award":["049321"],"award-info":[{"award-number":["049321"]}],"id":[{"id":"10.13039\/501100003549","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropeptides"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.npep.2016.08.009","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T07:20:25Z","timestamp":1472800825000},"page":"123-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Effects of alpha-melanocyte-stimulating hormone on mitochondrial energy metabolism in rats of different age-groups"],"prefix":"10.1016","volume":"64","author":[{"given":"Ren\u00e9 G.","family":"Feichtinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"P\u00e9terv\u00e1ri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michaela","family":"Zopf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Vidali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepideh","family":"Aminzadeh-Gohari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes A.","family":"Mayr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Kofler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rta","family":"Balask\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.npep.2016.08.009_bb0005","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ymgme.2009.06.012","article-title":"A novel mutation of the RRM2B gene in an infant with early fatal encephalomyopathy, central hypomyelination, and tubulopathy","volume":"98","author":"Acham-Roschitz","year":"2009","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.npep.2016.08.009_bb0010","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1074\/jbc.M603454200","article-title":"Peripheral effect of alpha-melanocyte-stimulating hormone on fatty acid oxidation in skeletal muscle","volume":"282","author":"An","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.npep.2016.08.009_bb0015","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jtherbio.2010.05.003","article-title":"Central alpha-MSH, energy balance, thermal balance, and antipyresis","volume":"35","author":"Balasko","year":"2010","journal-title":"Therm. Biol."},{"key":"10.1016\/j.npep.2016.08.009_bb0020","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00401-002-0638-1","article-title":"Severe depletion of mitochondrial DNA in spinal muscular atrophy","volume":"105","author":"Berger","year":"2003","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.npep.2016.08.009_bb0025","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1749-6632.2003.tb03191.x","article-title":"Alpha-melanocyte-stimulating hormone is a peripheral, integrative regulator of glucose and fat metabolism","volume":"994","author":"Brennan","year":"2003","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.npep.2016.08.009_bb0030","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1023\/A:1008983615045","article-title":"Role of the melanocortin-4 receptor in metabolic rate and food intake in mice","volume":"9","author":"Chen","year":"2000","journal-title":"Transgenic Res."},{"key":"10.1016\/j.npep.2016.08.009_bb0035","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1043-2760(99)00153-8","article-title":"The central melanocortin system and energy homeostasis","volume":"10","author":"Cone","year":"1999","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.npep.2016.08.009_bb0040","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/j.peptides.2004.11.033","article-title":"Regulation of thermogenesis by the central melanocortin system","volume":"26","author":"Fan","year":"2005","journal-title":"Peptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0045","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/1471-2407-10-149","article-title":"Low aerobic mitochondrial energy metabolism in poorly- or undifferentiated neuroblastoma","volume":"10","author":"Feichtinger","year":"2010","journal-title":"BMC Cancer"},{"key":"10.1016\/j.npep.2016.08.009_bb0050","first-page":"194","article-title":"Alterations of respiratory chain complexes in sporadic pheochromocytoma","volume":"3","author":"Feichtinger","year":"2011","journal-title":"Front. Biosci. (Elite Ed.)"},{"key":"10.1016\/j.npep.2016.08.009_bb0055","doi-asserted-by":"crossref","first-page":"884S","DOI":"10.3945\/ajcn.110.001917","article-title":"Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis","volume":"93","author":"Fernandez-Marcos","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.npep.2016.08.009_bb0060","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1093\/gerona\/glv070","article-title":"Reconsidering the role of mitochondria in aging","volume":"70","author":"Gonzalez-Freire","year":"2015","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.npep.2016.08.009_bb0065","doi-asserted-by":"crossref","first-page":"C1669","DOI":"10.1152\/ajpcell.00409.2002","article-title":"PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations","volume":"284","author":"Irrcher","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.npep.2016.08.009_bb0070","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1097\/00001756-200112040-00020","article-title":"Melanocortin receptor agonist transiently increases oxygen consumption in rats","volume":"12","author":"Jonsson","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.npep.2016.08.009_bb0075","doi-asserted-by":"crossref","first-page":"R173","DOI":"10.1152\/ajpregu.00394.2014","article-title":"Orexin system is expressed in avian muscle cells and regulates mitochondrial dynamics","volume":"308","author":"Lassiter","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.npep.2016.08.009_bb0080","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.peptides.2015.07.001","article-title":"Neuropeptide Y damages the integrity of mitochondrial structure and disrupts energy metabolism in cultured neonatal rat cardiomyocytes","volume":"71","author":"Luo","year":"2015","journal-title":"Peptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0085","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.cmet.2014.05.021","article-title":"Biphasic effect of melanocortin agonists on metabolic rate and body temperature","volume":"20","author":"Lute","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.npep.2016.08.009_bb0090","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1093\/carcin\/bgh104","article-title":"Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma","volume":"25","author":"Meierhofer","year":"2004","journal-title":"Carcinogenesis"},{"issue":"Spec No 2","key":"10.1016\/j.npep.2016.08.009_bb0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/gerona\/56.suppl_2.81","article-title":"Decreased food intake with aging","volume":"56","author":"Morley","year":"2001","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.npep.2016.08.009_bb0100","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0197-4580(88)80004-6","article-title":"Anorexia in the elderly","volume":"9","author":"Morley","year":"1988","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.npep.2016.08.009_bb0105","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1556\/APhysiol.96.2009.4.9","article-title":"Suppression of food intake by intracerebroventricular injection of alpha-MSH varies with age in rats","volume":"96","author":"Petervari","year":"2009","journal-title":"Acta Physiol. Hung."},{"key":"10.1016\/j.npep.2016.08.009_bb0110","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.npep.2010.03.002","article-title":"Age-dependence of alpha-MSH-induced anorexia","volume":"44","author":"Petervari","year":"2010","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0115","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.regpep.2010.10.002","article-title":"Central alpha-MSH infusion in rats: disparate anorexic vs. metabolic changes with aging","volume":"166","author":"Petervari","year":"2011","journal-title":"Regul. Pept."},{"key":"10.1016\/j.npep.2016.08.009_bb0120","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1096\/fj.09-147728","article-title":"Thyrotropin powers human mitochondria","volume":"24","author":"Poeggeler","year":"2010","journal-title":"FASEB J."},{"issue":"Suppl. 1","key":"10.1016\/j.npep.2016.08.009_bb0125","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1038\/sj.ijo.0802905","article-title":"Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha","volume":"29","author":"Puigserver","year":"2005","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.npep.2016.08.009_bb0130","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.febslet.2007.11.034","article-title":"Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways","volume":"582","author":"Rodgers","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1016\/j.npep.2016.08.009_bb0135","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jtherbio.2015.01.004","article-title":"Age-related alterations in the central thermoregulatory responsiveness to alpha-MSH","volume":"49-50","author":"Rostas","year":"2015","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.npep.2016.08.009_bb0140","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0009-8981(94)90055-8","article-title":"Biochemical and molecular investigations in respiratory chain deficiencies","volume":"228","author":"Rustin","year":"1994","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.npep.2016.08.009_bb0145","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1016\/S0028-3908(00)00014-9","article-title":"Impaired leptin signal transduction with age-related obesity","volume":"39","author":"Scarpace","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.npep.2016.08.009_bb0150","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.tem.2012.06.006","article-title":"Transcriptional integration of mitochondrial biogenesis","volume":"23","author":"Scarpulla","year":"2012","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.npep.2016.08.009_bb0155","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.npep.2014.05.004","article-title":"The modulatory role of alpha-melanocyte stimulating hormone administered spinally in the regulation of blood glucose level in d-glucose-fed and restraint stress mouse models","volume":"48","author":"Sim","year":"2014","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0160","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s12031-010-9462-6","article-title":"Complex catabolic effects of central alpha-MSH infusion in rats of altered nutritional states: differences from leptin","volume":"43","author":"Soos","year":"2011","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.npep.2016.08.009_bb0165","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0076-6879(69)13005-0","article-title":"Citrate synthase","volume":"13","author":"Srere","year":"1969","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.npep.2016.08.009_bb0170","doi-asserted-by":"crossref","first-page":"12419","DOI":"10.1523\/JNEUROSCI.3412-08.2008","article-title":"Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus","volume":"28","author":"Tung","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.npep.2016.08.009_bb0175","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.npep.2015.11.088","article-title":"Neuropeptide Y in noradrenergic neurons induces obesity in transgenic mouse models","volume":"55","author":"Vahatalo","year":"2016","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0180","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/jid.2013.286","article-title":"Hypothalamic-pituitary-thyroid axis hormones stimulate mitochondrial function and biogenesis in human hair follicles","volume":"134","author":"Vidali","year":"2014","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.npep.2016.08.009_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4899-1928-1_1","article-title":"An overview of muscle glucose uptake during exercise. Sites of regulation","volume":"441","author":"Wasserman","year":"1998","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.npep.2016.08.009_bb0190","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1677\/jme.0.0310291","article-title":"Hepatic gene expression patterns in thyroid hormone-treated hypothyroid rats","volume":"31","author":"Weitzel","year":"2003","journal-title":"J. Mol. Endocrinol."},{"key":"10.1016\/j.npep.2016.08.009_bb0195","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.peptides.2005.08.020","article-title":"Role of hypothalamic interleukin-1beta (IL-1beta) in regulation of energy homeostasis by melanocortins","volume":"27","author":"Wisse","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.npep.2016.08.009_bb0200","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.mce.2008.01.017","article-title":"T3-mediated expression of PGC-1alpha via a far upstream located thyroid hormone response element","volume":"287","author":"Wulf","year":"2008","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.npep.2016.08.009_bb0205","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1152\/physrev.2001.81.3.1097","article-title":"Physiological and molecular basis of thyroid hormone action","volume":"81","author":"Yen","year":"2001","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.npep.2016.08.009_bb0210","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/ijo.2009.232","article-title":"Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion","volume":"34","author":"Zhang","year":"2010","journal-title":"Int. J. Obes."}],"container-title":["Neuropeptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417916300890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417916300890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T05:57:00Z","timestamp":1655618220000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143417916300890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":42,"alternative-id":["S0143417916300890"],"URL":"https:\/\/doi.org\/10.1016\/j.npep.2016.08.009","relation":{},"ISSN":["0143-4179"],"issn-type":[{"value":"0143-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of alpha-melanocyte-stimulating hormone on mitochondrial energy metabolism in rats of different age-groups","name":"articletitle","label":"Article Title"},{"value":"Neuropeptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.npep.2016.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}