{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T14:26:32Z","timestamp":1769696792271,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuropeptides"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.npep.2024.102476","type":"journal-article","created":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T06:03:29Z","timestamp":1728540209000},"page":"102476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Adrenomedullin-mediated depressor response with visceral afferent-specific membrane depolarization in isolated nodose ganglion neurons from adult female rat"],"prefix":"10.1016","volume":"108","author":[{"given":"Yan","family":"Feng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0005","doi-asserted-by":"crossref","first-page":"H891","DOI":"10.1152\/ajpheart.00869.2002","article-title":"Cardiovascular responses to substance P in the nucleus tractus solitarii: microinjection study in conscious rats","volume":"285","author":"Abdala","year":"2003","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"6 Pt 2","key":"10.1016\/j.npep.2024.102476_bb0010","first-page":"R1698","article-title":"Adrenomedullin microinjection into the area postrema increases blood pressure","volume":"272","author":"Allen","year":"1997","journal-title":"Am. J. Phys."},{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0015","doi-asserted-by":"crossref","first-page":"E26","DOI":"10.1002\/ibd.22891","article-title":"Adrenomedullin: a novel therapy for intractable ulcerative colitis","volume":"19","author":"Ashizuka","year":"2013","journal-title":"Inflamm. Bowel Dis."},{"issue":"8","key":"10.1016\/j.npep.2024.102476_bb0020","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.3390\/biomedicines9081068","article-title":"Adrenomedullin: a novel therapeutic for the treatment of inflammatory bowel disease","volume":"9","author":"Ashizuka","year":"2021","journal-title":"Biomedicines"},{"issue":"6","key":"10.1016\/j.npep.2024.102476_bb0025","doi-asserted-by":"crossref","first-page":"H910","DOI":"10.1152\/ajpheart.00332.2014","article-title":"An afferent explanation for sexual dimorphism in the aortic baroreflex of rat","volume":"307","author":"Santa Cruz Chavez","year":"2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"1","key":"10.1016\/j.npep.2024.102476_bb0030","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/s41401-023-01154-y","article-title":"Piezo1 channel activation facilitates baroreflex afferent neurotransmission with subsequent blood pressure reduction in control and hypertension rats","volume":"45","author":"Cui","year":"2024","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.npep.2024.102476_bb0035","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.npep.2015.07.003","article-title":"Role of cerebellar adrenomedullin in blood pressure regulation","volume":"54","author":"Figueira","year":"2015","journal-title":"Neuropeptides"},{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0040","first-page":"R513","article-title":"Tissue hypoxygenation activates the adrenomedullin system in vivo","volume":"278","author":"Hofbauer","year":"2000","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"issue":"1","key":"10.1016\/j.npep.2024.102476_bb0045","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1476-5381.2011.01530.x","article-title":"The pharmacology of adrenomedullin 2\/intermedin","volume":"166","author":"Hong","year":"2012","journal-title":"Br. J. Pharmacol."},{"issue":"5","key":"10.1016\/j.npep.2024.102476_bb0050","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.3892\/etm.2015.2345","article-title":"Plasma concentrations of adrenomedullin and natriuretic peptides in patients with essential hypertension","volume":"9","author":"Hu","year":"2015","journal-title":"Exp. Ther. Med."},{"issue":"3","key":"10.1016\/j.npep.2024.102476_bb0055","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41440-021-00806-y","article-title":"Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases","volume":"45","author":"Kita","year":"2022","journal-title":"Hypertens. Res."},{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0060","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1006\/bbrc.1993.1451","article-title":"Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma","volume":"192","author":"Kitamura","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.npep.2024.102476_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.autneu.2023.103137","article-title":"Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease","volume":"251","author":"Lataro","year":"2024","journal-title":"Auton. Neurosci."},{"issue":"1","key":"10.1016\/j.npep.2024.102476_bb0070","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jneumeth.2007.04.003","article-title":"Electrophysiological and pharmacological validation of vagal afferent fiber type of neurons enzymatically isolated from rat nodose ganglia","volume":"164","author":"Li","year":"2007","journal-title":"J. Neurosci. Methods"},{"issue":"4","key":"10.1016\/j.npep.2024.102476_bb0075","first-page":"R1301","article-title":"Electrophysiological and neuroanatomical evidence of sexual dimorphism in aortic baroreceptor and vagal afferents in rat","volume":"295","author":"Li","year":"2008","journal-title":"Am. J. Phys. Regul. Integr. Comp. Phys."},{"issue":"3","key":"10.1016\/j.npep.2024.102476_bb0080","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/cns.13792","article-title":"Bradykinin-mediated estrogen-dependent depressor response by direct activation of female-specific distribution of myelinated ah-type baroreceptor neurons in rats","volume":"28","author":"Li","year":"2022","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.npep.2024.102476_bb0085","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.neuroscience.2016.02.008","article-title":"Prostaglandin E2-mediated upregulation of neuroexcitation and persistent tetrodotoxin-resistant Na+ currents in ah-type trigeminal ganglion neurons isolated from adult female rats","volume":"320","author":"Liu","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.npep.2024.102476_bb0090","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.neulet.2014.03.039","article-title":"Myelinated ah-type trigeminal ganglion neurons in female rats: neuroexcitability, chemosensitivity to histamine, and potential clinical impact","volume":"567","author":"Liu","year":"2014","journal-title":"Neurosci. Lett."},{"issue":"8","key":"10.1016\/j.npep.2024.102476_bb0095","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1038\/s41440-024-01701-y","article-title":"Adrenomedullin improved endothelial dysfunction via receptor-Akt pathway in rats with obesity-related hypertension","volume":"47","author":"Liu","year":"2024","journal-title":"Hypertens. Res."},{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0100","doi-asserted-by":"crossref","first-page":"215","DOI":"10.4149\/gpb_2013073","article-title":"Adrenomedullin and the calcitonin receptor-like receptor system mRNA expressions in the rat heart and sensory ganglia in experimentally-induced long-term diabetes","volume":"33","author":"Mistrova","year":"2014","journal-title":"Gen. Physiol. Biophys."},{"issue":"5","key":"10.1016\/j.npep.2024.102476_bb0105","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/jhh.2016.96","article-title":"Haplotype-based, case-control study of the receptor (calcitonin) activity-modifying protein (RAMP) 1 gene in essential hypertension","volume":"31","author":"Nakayama","year":"2017","journal-title":"J. Hum. Hypertens."},{"issue":"21","key":"10.1016\/j.npep.2024.102476_bb0110","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.3390\/cells11213498","article-title":"Src family kinases facilitate the crosstalk between CGRP and cytokines in sensitizing trigeminal ganglion via transmitting CGRP receptor\/PKA pathway","volume":"11","author":"Nie","year":"2022","journal-title":"Cells"},{"issue":"10","key":"10.1016\/j.npep.2024.102476_bb0115","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1002\/ejhf.2664","article-title":"Congestion in heart failure: a circulating biomarker-based perspective. A review from the biomarkers working Group of the Heart Failure Association, European Society of Cardiology","volume":"24","author":"Nunez","year":"2022","journal-title":"Eur. J. Heart Fail."},{"issue":"6","key":"10.1016\/j.npep.2024.102476_bb0120","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3390\/ph15060719","article-title":"Adrenomedullin improves cardiac remodeling and function in obese rats with hypertension","volume":"15","author":"Qian","year":"2022","journal-title":"Pharmaceuticals (Basel)"},{"issue":"8","key":"10.1016\/j.npep.2024.102476_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0071184","article-title":"Remodeling of hyperpolarization-activated current, Ih, in ah-type visceral ganglion neurons following ovariectomy in adult rats","volume":"8","author":"Qiao","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.npep.2024.102476_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2024.102418","article-title":"Baroreflex afferent function is a part of insights of leptin-mediated blood pressure reduction and leptin-resistance hypertension","volume":"105","author":"Ren","year":"2024","journal-title":"Neuropeptides"},{"issue":"1","key":"10.1016\/j.npep.2024.102476_bb0135","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1210\/en.2005-0664","article-title":"Female sex steroids increase adrenomedullin-induced vasodilation by increasing the expression of adrenomedullin2 receptor components in rat mesenteric artery","volume":"147","author":"Ross","year":"2006","journal-title":"Endocrinology"},{"issue":"15","key":"10.1016\/j.npep.2024.102476_bb0140","doi-asserted-by":"crossref","first-page":"12268","DOI":"10.3390\/ijms241512268","article-title":"Migraine treatment: towards new pharmacological targets","volume":"24","author":"Silvestro","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.npep.2024.102476_bb0145","doi-asserted-by":"crossref","first-page":"892","DOI":"10.3390\/cells13110892","article-title":"A focus on the pathophysiology of adrenomedullin expression: endothelitis and organ damage in severe viral and bacterial infections","volume":"13","author":"Spoto","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.npep.2024.102476_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2021.102213","article-title":"How neuroactive factors mediates immune responses during pregnancy: an interdisciplinary view","volume":"91","author":"Sun","year":"2022","journal-title":"Neuropeptides"},{"key":"10.1016\/j.npep.2024.102476_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2020.102109","article-title":"Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway","volume":"85","author":"Sun","year":"2021","journal-title":"Neuropeptides"},{"issue":"12","key":"10.1016\/j.npep.2024.102476_bb0160","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1038\/s41401-021-00722-4","article-title":"Estrogen-dependent KCa1.1 modulation is essential for retaining neuroexcitation of female-specific subpopulation of myelinated ah-type baroreceptor neurons in rats","volume":"42","author":"Wang","year":"2021","journal-title":"Acta Pharmacol. Sin."},{"issue":"4","key":"10.1016\/j.npep.2024.102476_bb0165","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.3390\/ijms24043943","article-title":"Adrenomedullin improves hypertension and vascular remodeling partly through the receptor-mediated AMPK pathway in rats with obesity-related hypertension","volume":"24","author":"Wang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.npep.2024.102476_bb0170","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/HJH.0000000000003301","article-title":"Adrenomedullin in paraventricular nucleus attenuates adipose afferent reflex and sympathoexcitation via receptors mediated nitric oxide-gamma-aminobutyric acid a type receptor pathway in rats with obesity-related hypertension","volume":"41","author":"Wang","year":"2023","journal-title":"J. Hypertens."},{"issue":"5","key":"10.1016\/j.npep.2024.102476_bb0175","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.ccell.2024.03.013","article-title":"Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization","volume":"42","author":"Wang","year":"2024","journal-title":"Cancer Cell"},{"key":"10.1016\/j.npep.2024.102476_bb0180","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.neuroscience.2022.04.008","article-title":"Ah-type baroreceptor neurons expressing estrogen dependent mGluR7 mediate descending inhibition of cardiac nociception","volume":"492","author":"Wen","year":"2022","journal-title":"Neuroscience"},{"issue":"9","key":"10.1016\/j.npep.2024.102476_bb0185","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1038\/s41401-022-00867-w","article-title":"Estrogen-dependent depressor response of melatonin via baroreflex afferent function and intensification of PKC-mediated Na(v)1.9 activation","volume":"43","author":"Wu","year":"2022","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.npep.2024.102476_bb0190","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/cns.12993","article-title":"Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation","volume":"25","author":"Yuan","year":"2019","journal-title":"CNS Neurosci. Ther."},{"issue":"12","key":"10.1016\/j.npep.2024.102476_bb0195","first-page":"881","article-title":"Adrenomedullin and non-dipping circadian pattern in newly diagnosed essential hypertension","volume":"121","author":"Yucel","year":"2020","journal-title":"Bratisl. Lek. Listy"},{"issue":"9","key":"10.1016\/j.npep.2024.102476_bb0200","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1113\/EP087613","article-title":"Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats","volume":"104","author":"Zoccal","year":"2019","journal-title":"Exp. Physiol."}],"container-title":["Neuropeptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417924000751?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0143417924000751?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T20:47:32Z","timestamp":1731617252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0143417924000751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":40,"alternative-id":["S0143417924000751"],"URL":"https:\/\/doi.org\/10.1016\/j.npep.2024.102476","relation":{},"ISSN":["0143-4179"],"issn-type":[{"value":"0143-4179","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adrenomedullin-mediated depressor response with visceral afferent-specific membrane depolarization in isolated nodose ganglion neurons from adult female rat","name":"articletitle","label":"Article Title"},{"value":"Neuropeptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.npep.2024.102476","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102476"}}