{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T05:13:44Z","timestamp":1761887624294,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurolog\u00eda (English Edition)"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.nrleng.2023.12.008","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T11:50:45Z","timestamp":1701863445000},"page":"43-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["High frequency of endoluminal thrombus in patients with ischaemic stroke following AARS-CoV-2 infection"],"prefix":"10.1016","volume":"39","author":[{"given":"P.","family":"G\u00f3mez-Porro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Cabal-Paz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Valenzuela-Chamorro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Desanvicente-Celis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Sabin-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ochoa-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Fl\u00f3rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Enr\u00edquez-Calzada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mart\u00edn-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00cd.","family":"Esain-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Garc\u00eda-Fleitas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Silva-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1.","family":"Ruiz-Molina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gamo-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dur\u00e1n-Lozano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Velasco-Calvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Alba-Alc\u00e1ntara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Gonz\u00e1lez-Santiago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Callejas-D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Brea-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-C.","family":"Salazar-Uribe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Escamilla-Crespo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Carneado-Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nrleng.2023.12.008_bib0005","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.bbi.2020.04.077","article-title":"COVID-19 presenting as stroke","volume":"87","author":"Avula","year":"2020","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0010","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1136\/jnnp-2020-323586","article-title":"Characteristics of ischaemic stroke associated with COVID-19","volume":"91","author":"Beyrouti","year":"2020","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0015","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s12975-020-00818-9","article-title":"COVID-19-related stroke","volume":"11","author":"Hess","year":"2020","journal-title":"Transl. Stroke Res"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0020","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1161\/STROKEAHA.120.030335","article-title":"SARS2-CoV-2 and stroke in a New York healthcare system","volume":"51","author":"Yaghi","year":"2020","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0025","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1161\/STROKEAHA.120.030365","article-title":"Clinical characteristics and outcomes of COVID-19 patients with a history of stroke in Wuhan, China","volume":"51","author":"Qin","year":"2020","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0030","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1161\/STROKEAHA.109.553446","article-title":"Validation and refinement of the ABCD2 Score","volume":"40","author":"Fothergill","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0035","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/01.STR.24.1.35","article-title":"Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of ORG 10172 in Acute Stroke Treatment","volume":"24","author":"Adams","year":"1993","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000352050","article-title":"The ASCOD phenotyping of ischemic stroke (updated ASCO phenotyping)","volume":"36","author":"Amarenco","year":"2013","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0045","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1161\/01.STR.22.10.1242","article-title":"Assessment of scales of disability and handicap for stroke patients","volume":"22","author":"Wolfe","year":"1991","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0050","first-page":"CD1","article-title":"Calculated decisions: Brescia-COVID respiratory severity scale (BCRSS)\/algorithm","volume":"22","author":"Brescia-COVID Group","year":"2020","journal-title":"Emerg Med Pract"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0055","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0060","doi-asserted-by":"crossref","first-page":"R373","DOI":"10.1152\/ajpregu.00292.2006","article-title":"Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system","volume":"292","author":"Doobay","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0065","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1152\/ajpregu.00222.2010","article-title":"ACE2\/ANG-(1-7)\/Mas pathway in the brain: the axis of good","volume":"300","author":"Xu","year":"2011","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0070","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1111\/jth.14844","article-title":"Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19","volume":"18","author":"Dolhnikoff","year":"2020","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0075","first-page":"771","article-title":"Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China","author":"Mao","year":"2020","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0080","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1056\/NEJMc2009787","article-title":"Large-vessel stroke as a presenting feature of covid-19 in the young","volume":"382","author":"Oxley","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0085","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1161\/STROKEAHA.113.002289","article-title":"High-sensitivity C-reactive protein and interleukin-6-dominant Inflammation and Ischemic Stroke Risk: The Northern Manhattan Study","volume":"45","author":"Luna","year":"2014","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0090","first-page":"1799","article-title":"Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis","volume":"294","author":"Fibrinogen Studies Collaboration","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0095","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1161\/01.CIR.101.15.1785","article-title":"Interferon-gamma and lipopolysaccharide potentiate monocyte tissue factor induction by C-reactive protein: relationship with age, sex, and hormone replacement treatment","volume":"18","author":"Nakagomi","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0100","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nrneurol.2016.125","article-title":"Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke","volume":"12","author":"Esenwa","year":"2016","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0105","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/S0741-5214(03)00709-2","article-title":"High-sensitivity C-reactive protein in high-grade carotid stenosis: risk marker for unstable carotid plaque","volume":"38","author":"Garcia","year":"2003","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0110","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/jth.14768","article-title":"Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia","volume":"18","author":"Tang","year":"2020","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0115","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1182\/blood.2020006000","article-title":"COVID-19 and its implication for thrombosis and anticoagulation","volume":"135","author":"Connors","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0120","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1161\/STROKEAHA.118.023015","article-title":"Intraluminal thrombi in the cervico-cephalic arteries. Clinical-imaging manifestations, treatment strategies, and outcome","volume":"50","author":"Singh","year":"2019","journal-title":"Stroke"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0125","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1111\/jth.14938","article-title":"Macrothrombosis and stroke in patients with mild Covid-19 infection","volume":"18","author":"Fara","year":"2020","journal-title":"J Thromb Haemost"},{"issue":"9","key":"10.1016\/j.nrleng.2023.12.008_bib0130","first-page":"1677","article-title":"Intraluminal carotid artery thrombus in COVID-19: another danger of cytokine storm?","volume":"41","author":"Mohamud","year":"2020","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0135","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S1474-4422(08)70061-9","article-title":"Acute ischaemic stroke and infection: recent and emerging concepts","volume":"7","author":"Emsley","year":"2008","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0140","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0140-6736(16)30506-2","article-title":"Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study","volume":"388","author":"O\u2019Donnell","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0145","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000090528","article-title":"Hypoxaemia in acute stroke is frequent and worsens outcome","volume":"21","author":"Rowat","year":"2006","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.nrleng.2023.12.008_bib0150","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.nrl.2020.04.008","article-title":"Acute stroke care during the COVID-19 pandemic. Ictus Madrid Program recommendations","volume":"35","author":"Rodr\u00edguez-Pardo","year":"2020","journal-title":"Neurologia"}],"container-title":["Neurolog\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173580823000755?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173580823000755?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T03:35:53Z","timestamp":1761881753000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2173580823000755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S2173580823000755"],"URL":"https:\/\/doi.org\/10.1016\/j.nrleng.2023.12.008","relation":{},"ISSN":["2173-5808"],"issn-type":[{"type":"print","value":"2173-5808"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High frequency of endoluminal thrombus in patients with ischaemic stroke following AARS-CoV-2 infection","name":"articletitle","label":"Article Title"},{"value":"Neurolog\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nrleng.2023.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.nrl.2021.04.012","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Sociedad Espa\u00f1ola de Neurolog\u00eda. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}