{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:55:26Z","timestamp":1792101326253,"version":"4.4.0"},"reference-count":103,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019418","name":"NIHR Maudsley Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009362","name":"South London and Maudsley NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neuroscience Applied"],"published-print":{"date-parts":[[2023]]},"DOI":"10.1016\/j.nsa.2022.101014","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T17:21:24Z","timestamp":1667323284000},"page":"101014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Peripheral inflammatory effects of different interventions for treatment-resistant depression: A systematic review"],"prefix":"10.1016","volume":"2","author":[{"given":"Rebecca","family":"Strawbridge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefany","family":"Izurieta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elana","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Tee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8030-4597","authenticated-orcid":false,"given":"Co Co","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2291-6952","authenticated-orcid":false,"given":"Allan H.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6990-939X","authenticated-orcid":false,"given":"Anthony J.","family":"Cleare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nsa.2022.101014_bib1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.bbi.2020.07.018","article-title":"Decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex","volume":"89","author":"Adams","year":"2020","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib2","first-page":"28","article-title":"The effect of low-dose of ketamine infusion on stress responses in coronary artery bypass graft surgery","volume":"4","author":"Akhlagh","year":"2010","journal-title":"Iran Cardiovasc Res J"},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib3","doi-asserted-by":"crossref","first-page":"282","DOI":"10.4103\/aer.AER_28_17","article-title":"Effect of single compared to repeated doses of intravenous S(+) ketamine on the release of pro-inflammatory cytokines in patients undergoing radical prostatectomy","volume":"11","author":"Ali","year":"2017","journal-title":"Anesth. Essays Res."},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib4","article-title":"Ketamine versus dexmedetomidine sedation in the attenuation of surgical stress response and postoperative pain: a retrospective study","volume":"12","author":"Altiparmak","year":"2018","journal-title":"J.\u00a0Clin. Diagn. Res."},{"key":"10.1016\/j.nsa.2022.101014_bib5","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.euroneuro.2021.10.863","article-title":"Stratified psychiatry: tomorrow's precision psychiatry?","volume":"55","author":"Arns","year":"2022","journal-title":"Eur. Neuropsychopharmacol. J. Eur. Coll. Neuropsychopharmacol."},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib6","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000506133","article-title":"Inflammation, hippocampal volume, and therapeutic outcome following electroconvulsive therapy in depressive patients: a pilot study","volume":"79","author":"Belge","year":"2020","journal-title":"Neuropsychobiology"},{"issue":"12","key":"10.1016\/j.nsa.2022.101014_bib7","doi-asserted-by":"crossref","first-page":"e488","DOI":"10.1038\/tp.2014.129","article-title":"Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits","volume":"4","author":"Beurel","year":"2014","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib8","first-page":"328","article-title":"Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial","volume":"13","author":"Bhutta","year":"2012","journal-title":"Pediatr. Crit. Care Med. J. Soc. Crit. Care Med. World Fed. Pediatr. Intens. Crit. Care Soc."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib9","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.pnpbp.2007.06.031","article-title":"The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-\u03b3","volume":"32","author":"Bian","year":"2008","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib10","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.intimp.2005.12.007","article-title":"A\u00a0new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice","volume":"6","author":"Brustolim","year":"2006","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.nsa.2022.101014_bib11","article-title":"Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline","volume":"368","author":"Campbell","year":"2020","journal-title":"BMJ"},{"issue":"5\u20136","key":"10.1016\/j.nsa.2022.101014_bib12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/09540261.2020.1765748","article-title":"Relative effectiveness of augmentation treatments for treatment-resistant depression: a systematic review and network meta-analysis","volume":"32","author":"Carter","year":"2020","journal-title":"Int. Rev. Psychiatr."},{"key":"10.1016\/j.nsa.2022.101014_bib13","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.psychres.2018.08.078","article-title":"Rapid inflammation modulation and antidepressant efficacy of a low-dose ketamine infusion in treatment-resistant depression: a randomized, double-blind control study","volume":"269","author":"Chen","year":"2018","journal-title":"Psychiatr. Res."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/bja\/aen325","article-title":"Effect of low-dose ketamine on inflammatory response in off-pump coronary artery bypass graft surgery","volume":"102","author":"Cho","year":"2009","journal-title":"Br. J. Anaesth."},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib15","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s12630-021-01925-3","article-title":"The immunomodulatory effect of ketamine in colorectal cancer surgery: a randomized-controlled trial","volume":"68","author":"Cho","year":"2021","journal-title":"Can. J. Anesth."},{"key":"10.1016\/j.nsa.2022.101014_bib16","doi-asserted-by":"crossref","first-page":"646701","DOI":"10.3389\/fphar.2021.646701","article-title":"Aripiprazole as a candidate treatment of COVID-19 identified through genomic analysis","volume":"12","author":"Crespo-Facorro","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.nsa.2022.101014_bib17","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1213\/ANE.0b013e3182662e30","article-title":"Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis","volume":"115","author":"Dale","year":"2012","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.nsa.2022.101014_bib18","series-title":"Cochrane Handbook for Systematic Reviews of Interventions Version 6.3","article-title":"Chapter 10: analysing data and undertaking meta-analyses","author":"Deeks","year":"2022"},{"issue":"4","key":"10.1016\/j.nsa.2022.101014_bib19","first-page":"291","article-title":"The pattern of change in depressive symptoms and inflammatory markers after electroconvulsive therapy: a systematic review","volume":"37","author":"Desfoss\u00e9s","year":"2021","journal-title":"J.\u00a0ECT"},{"issue":"22","key":"10.1016\/j.nsa.2022.101014_bib20","first-page":"3721","article-title":"Effects of preoperative ketamine on the endocrine-metabolic and inflammatory response to laparoscopic surgery","volume":"124","author":"Du","year":"2011","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.nsa.2022.101014_bib21","first-page":"1","article-title":"A\u00a0randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery","author":"D'Alonzo","year":"2011","journal-title":"J.\u00a0Anesth."},{"issue":"7","key":"10.1016\/j.nsa.2022.101014_bib22","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1177\/0269881108091077","article-title":"Effects of bupropion augmentation on pro-inflammatory cytokines in escitalopram-resistant patients with major depressive disorder","volume":"23","author":"Eller","year":"2009","journal-title":"J.\u00a0Psychopharmacol. Oxf. Engl."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1186\/s13643-019-1172-8","article-title":"Risk of bias tools in systematic reviews of health interventions: an analysis of PROSPERO-registered protocols","volume":"8","author":"Farrah","year":"2019","journal-title":"Syst. Rev."},{"key":"10.1016\/j.nsa.2022.101014_bib24","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12888-018-1679-x","article-title":"Standardisation framework for the Maudsley staging method for treatment resistance in depression","volume":"18","author":"Fekadu","year":"2018","journal-title":"BMC Psychiatr."},{"key":"10.1016\/j.nsa.2022.101014_bib25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.npbr.2019.07.007","article-title":"Changes in inflammation with treatment for bipolar II depression: pilot trial data on differential effects of psychotherapy and medication","volume":"33","author":"Fiedorowicz","year":"2019","journal-title":"Neurol. Psychiatr. Brain Res."},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib26","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/icvts\/ivv154","article-title":"Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, placebo-controlled clinical trial","volume":"21","author":"Fiorelli","year":"2015","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"issue":"1\u20133","key":"10.1016\/j.nsa.2022.101014_bib27","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.jad.2010.11.035","article-title":"Electroconvulsive therapy has acute immunological and neuroendocrine effects in patients with major depressive disorder","volume":"131","author":"Fluitman","year":"2011","journal-title":"J.\u00a0Affect. Disord."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000441521","article-title":"Inflammatory cytokines and antipsychotic-induced weight gain: review and clinical implications","volume":"2","author":"Fonseka","year":"2016","journal-title":"Compl. Psychiatr."},{"key":"10.1016\/j.nsa.2022.101014_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.797577","article-title":"Depression, estrogens, and neuroinflammation: a preclinical review of ketamine treatment for mood disorders in women","volume":"12","author":"Gagne","year":"2022","journal-title":"Front. Psychiatr."},{"issue":"Pt C","key":"10.1016\/j.nsa.2022.101014_bib30","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.pnpbp.2017.03.016","article-title":"The anti-inflammatory mechanism of antidepressants - SSRIs, SNRIs","volume":"80","author":"Ga\u0142ecki","year":"2018","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib31","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/JCP.0000000000000927","article-title":"A\u00a0pilot study of the effectiveness of lithium versus quetiapine immediate release monotherapy in patients with bipolar spectrum disorders","volume":"38","author":"Gao","year":"2018","journal-title":"J.\u00a0Clin. Psychopharmacol."},{"key":"10.1016\/j.nsa.2022.101014_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2021.113735","article-title":"Cytokines changes associated with electroconvulsive therapy in patients with treatment-resistant depression: a Meta-analysis","volume":"297","author":"Gay","year":"2021","journal-title":"Psychiatr. Res."},{"issue":"4","key":"10.1016\/j.nsa.2022.101014_bib33","first-page":"251","article-title":"Analgesic and anti-inflammatory activities of bupropion in animal models","volume":"9","author":"Hajhashemi","year":"2014","journal-title":"Res Pharm Sci."},{"issue":"4","key":"10.1016\/j.nsa.2022.101014_bib34","first-page":"183","article-title":"Raised plasma levels of tumor necrosis factor alpha in patients with depression: normalization during electroconvulsive therapy","volume":"19","author":"Hestad","year":"2003","journal-title":"J.\u00a0ECT"},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib35","first-page":"682","article-title":"Effect of preemptive analgesia by intravenous small-dose ketamine on cytokine response to upper abdominal surgery","volume":"27","author":"Huang","year":"2006","journal-title":"Med. J. Wuhan Univ."},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib36","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1053\/j.jvca.2008.12.021","article-title":"Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass","volume":"23","author":"Hudetz","year":"2009","journal-title":"J.\u00a0Cardiothorac. Vasc. Anesth."},{"issue":"10","key":"10.1016\/j.nsa.2022.101014_bib37","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S2215-0366(20)30391-6","article-title":"Trial failures of anti-inflammatory drugs in depression \u2013 authors' reply","volume":"7","author":"Husain","year":"2020","journal-title":"Lancet Psychiatr."},{"issue":"7","key":"10.1016\/j.nsa.2022.101014_bib38","doi-asserted-by":"crossref","first-page":"549","DOI":"10.4103\/ija.IJA_607_16","article-title":"Effect of ketamine on pro- and anti-inflammatory cytokine response in paediatric cardiac surgery: a prospective randomised controlled study","volume":"61","author":"Ibrahim","year":"2017","journal-title":"Indian J. Anaesth."},{"issue":"7","key":"10.1016\/j.nsa.2022.101014_bib39","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.pnpbp.2011.05.011","article-title":"Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders","volume":"35","author":"Igue","year":"2011","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib40","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1186\/s12888-019-2222-4","article-title":"The humanistic and economic burden of treatment-resistant depression in Europe: a cross-sectional study","volume":"19","author":"Jaffe","year":"2019","journal-title":"BMC Psychiatr."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib41","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/acps.12665","article-title":"Changes in interleukin-6 levels during electroconvulsive therapy may reflect the therapeutic response in major depression","volume":"135","author":"J\u00e4rventausta","year":"2017","journal-title":"Acta Psychiatr. Scand."},{"issue":"4","key":"10.1016\/j.nsa.2022.101014_bib42","doi-asserted-by":"crossref","DOI":"10.1192\/bjo.2020.43","article-title":"Inflammation as a treatment target in mood disorders: review","volume":"6","author":"Jones","year":"2020","journal-title":"BJPsych Open"},{"key":"10.1016\/j.nsa.2022.101014_bib43","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.schres.2018.06.039","article-title":"Comparison of the anti-inflammatory effect of aripiprazole and risperidone in 75 drug-na\u00efve first episode psychosis individuals: a 3 months randomized study","volume":"202","author":"Juncal-Ruiz","year":"2018","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib44","first-page":"69","article-title":"Protective effects of quetiapine on metabolic and inflammatory abnormalities in schizophrenic patients during exacerbated stage","volume":"59","author":"Kao","year":"2016","journal-title":"Chin. J. Physiol."},{"key":"10.1016\/j.nsa.2022.101014_bib45","article-title":"Effects of celecoxib on inflammatory markers in bipolar patients undergoing electroconvulsive therapy: a placebo-controlled, double-blind, randomised study","volume":"144","author":"Kargar","year":"2014","journal-title":"Swiss Med. Wkly."},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib46","first-page":"174","article-title":"Ceren acar. Effects of electroconvulsive therapy on some inflammatory factors in patients with treatment-resistant schizophrenia","volume":"32","author":"Kartalci","year":"2016","journal-title":"J.\u00a0ECT"},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib47","first-page":"217","article-title":"The effect of a small dose of ketamine on postoperative analgesia and cytokine changes after laparoscopic cholecystectomy","volume":"33","author":"Kartalov","year":"2012","journal-title":"Prilozi"},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib48","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0163-8343(03)00093-8","article-title":"Anti- and pro-inflammatory considerations in antidepressant use during medical illness: bupropion lowers and mirtazapine increases circulating tumor necrosis factor-alpha levels","volume":"25","author":"Kast","year":"2003","journal-title":"Gen. Hosp. Psychiatr."},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib49","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1053\/gast.2001.29467","article-title":"Remission of Crohn's disease on bupropion","volume":"121","author":"Kast","year":"2001","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib50","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.31","article-title":"Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome","volume":"7","author":"Kiraly","year":"2017","journal-title":"Transl. Psychiatry"},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib51","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1192\/bjp.2021.37","article-title":"Electroconvulsive therapy for depression: 80 years of progress","volume":"219","author":"Kirov","year":"2021","journal-title":"Br. J. Psychiatr. J. Ment. Sci."},{"issue":"8","key":"10.1016\/j.nsa.2022.101014_bib52","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1177\/02698811211026426","article-title":"Ketamine's effect on inflammation and kynurenine pathway in depression: a systematic review","volume":"35","author":"Kopra","year":"2021","journal-title":"J.\u00a0Psychopharmacol."},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib53","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1136\/jnnp-2011-301779","article-title":"Depression: an inflammatory illness?","volume":"83","author":"Krishnadas","year":"2012","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib54","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.17m11597","article-title":"Inflammation and improvement of depression following electroconvulsive therapy in treatment-resistant depression","volume":"79","author":"Kruse","year":"2018","journal-title":"J.\u00a0Clin. Psychiatr."},{"key":"10.1016\/j.nsa.2022.101014_bib55","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.bbi.2020.05.069","article-title":"Inflammation and depression treatment response to electroconvulsive therapy: sex-specific role of interleukin-8","volume":"89","author":"Kruse","year":"2020","journal-title":"Brain Behav. Immun."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib56","first-page":"88","article-title":"Increase in plasma proinflammatory cytokines after electroconvulsive therapy in patients with depressive disorder","volume":"24","author":"Lehtim\u00e4ki","year":"2008","journal-title":"J.\u00a0ECT"},{"key":"10.1016\/j.nsa.2022.101014_bib57","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jad.2014.12.033","article-title":"IL-23 and TGF-\u03b21 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode","volume":"174","author":"Li","year":"2015","journal-title":"J.\u00a0Affect. Disord."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib58","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/s41380-019-0474-5","article-title":"Peripheral cytokine levels and response to antidepressant treatment in depression: a systematic review and meta-analysis","volume":"25","author":"Liu","year":"2019","journal-title":"Mol. Psychiatr."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib59","doi-asserted-by":"crossref","first-page":"500","DOI":"10.4314\/ahs.v17i2.25","article-title":"Effect of low-dose ketamine on post-operative serum IL-6 production among elective surgical patients: a randomized clinical trial","volume":"17","author":"Luggya","year":"2017","journal-title":"Afr. Health Sci."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib60","first-page":"128","article-title":"Influence of dexmedetomidine and sub-anesthetic dose of ketamine on postoperative delirium in elderly orthopedic patients under total intravenous anesthesia","volume":"39","author":"Ma","year":"2013","journal-title":"J.\u00a0Jilin Univ. (Sci. Ed.)"},{"issue":"3","key":"10.1016\/j.nsa.2022.101014_bib61","first-page":"88","article-title":"Effects of lithium carbonate on cytokine production in patients affected by breast cancer","volume":"8","author":"Merendino","year":"1994","journal-title":"J.\u00a0Biol. Regul. Homeost. Agents"},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib62","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/15622975.2019.1618494","article-title":"Cytokine-mediated cellular immune activation in electroconvulsive therapy: a CSF study in patients with treatment-resistant depression","volume":"21","author":"Mindt","year":"2020","journal-title":"World J. Biol. Psychiatr. Off. J. World Fed. Soc. Biol. Psychiatr."},{"issue":"7","key":"10.1016\/j.nsa.2022.101014_bib63","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1038\/s41380-020-00878-1","article-title":"Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals","volume":"26","author":"Mkrtchian","year":"2021","journal-title":"Mol. Psychiatr."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib64","first-page":"137","article-title":"(+) ketamine suppresses TNF-\u03b1, IL-6 and IL-8 production in blood in major abdominal surgery under combined epidural-general anesthesia","volume":"8","author":"Mostafa","year":"2008","journal-title":"J.\u00a0Med. Sci."},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib65","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1021\/cn500038f","article-title":"Effects of lithium on inflammation","volume":"5","author":"Nassar","year":"2014","journal-title":"ACS Chem. Neurosci."},{"issue":"Suppl. 8","key":"10.1016\/j.nsa.2022.101014_bib66","first-page":"17","article-title":"Prevalence and management of treatment-resistant depression","volume":"68","author":"Nemeroff","year":"2007","journal-title":"J.\u00a0Clin. Psychiatr."},{"issue":"5","key":"10.1016\/j.nsa.2022.101014_bib67","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/s41386-020-00948-6","article-title":"Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial","volume":"46","author":"Nettis","year":"2021","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.nsa.2022.101014_bib68","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jpsychires.2016.09.025","article-title":"Change in cytokine levels is not associated with rapid antidepressant response to ketamine in treatment-resistant depression","volume":"84","author":"Park","year":"2017","journal-title":"J.\u00a0Psychiatr. Res."},{"key":"10.1016\/j.nsa.2022.101014_bib69","unstructured":"Park M, Luckenbaugh DA, Newman LE, Niciu MJ, Lener MS, Machado-Vieira R, et\u00a0al.. Change in cytokine levels is not associated with antidepressant response to ketamine in patients with treatment resistant depression. Biol. Psychiatr.. 79(9):69S\u201370S."},{"key":"10.1016\/j.nsa.2022.101014_bib70","article-title":"Growth factor proteins and treatment-resistant depression: a place on the path to precision","author":"Pisoni","year":"2020","journal-title":"Front Psychiat. [Internet]"},{"issue":"9","key":"10.1016\/j.nsa.2022.101014_bib71","first-page":"17","article-title":"Inflammation and treatment resistance in major depression: the perfect storm","volume":"30","author":"Raison","year":"2013","journal-title":"Psychiatr. Times"},{"key":"10.1016\/j.nsa.2022.101014_bib72","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jpsychires.2017.10.002","article-title":"Cytokine serum levels remain unchanged during lithium augmentation of antidepressants in major depression","volume":"96","author":"Ricken","year":"2018","journal-title":"J.\u00a0Psychiatr. Res."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib73","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1213\/00000539-199808000-00006","article-title":"Ketamine attenuates the interleukin-6 response after cardiopulmonary bypass","volume":"87","author":"Roytblat","year":"1998","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.nsa.2022.101014_bib74","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jad.2016.06.035","article-title":"Alteration of immune markers in a group of melancholic depressed patients and their response to electroconvulsive therapy","volume":"205","author":"Rush","year":"2016","journal-title":"J.\u00a0Affect. Disord."},{"issue":"02698811221104058.","key":"10.1016\/j.nsa.2022.101014_bib75","article-title":"Systematic review and meta-analysis of augmentation and combination treatments for early-stage treatment-resistant depression","volume":"21","author":"Scott","year":"2022","journal-title":"J.\u00a0Psychopharmacol."},{"key":"10.1016\/j.nsa.2022.101014_bib76","first-page":"689","article-title":"Effectiveness of low-dose intravenous ketamine to attenuate stress response in patients undergoing emergency cesarean section with spinal anesthesia","volume":"9","author":"Senapathi","year":"2016","journal-title":"J.\u00a0Pain Res."},{"issue":"8","key":"10.1016\/j.nsa.2022.101014_bib77","first-page":"208","article-title":"Effectiveness of intravenous subanesthetic dose of ketamine on the subarachnoid block to attenuate inflammation response in transurethral resection of the prostate surgeries","volume":"11","author":"Senapathi","year":"2019","journal-title":"J.\u00a0Glob. Pharm. Technol."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib78","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0034-7094(12)70097-1","article-title":"Evaluation of preemptive effect of epidural S(+)-ketamine for hysterectomy: plasmatic concentrations of interleukins","volume":"62","author":"Silva","year":"2012","journal-title":"Rev. Bras. Anestesiol."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib79","first-page":"33","article-title":"Evaluation of low-dose ketamine on inflammatory biomarker profile following off-pump coronary artery bypass grafting","author":"Singh","year":"2020","journal-title":"J.\u00a0Card. Crit. Care TSS"},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib80","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.pharep.2014.09.007","article-title":"Therapeutic effect of aripiprazole in chronic schizophrenia is accompanied by anti-inflammatory activity","volume":"67","author":"Sobi\u015b","year":"2015","journal-title":"Pharmacol. Rep. PR"},{"key":"10.1016\/j.nsa.2022.101014_bib81","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"issue":"10","key":"10.1016\/j.nsa.2022.101014_bib82","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.euroneuro.2015.06.007","article-title":"Inflammation and clinical response to treatment in depression: a meta-analysis","volume":"25","author":"Strawbridge","year":"2015","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.nsa.2022.101014_bib83","series-title":"Inflammation and Immunity in Depression","first-page":"473","article-title":"Inflammation as a marker of clinical response to treatment: a focus on treatment-resistant depression","author":"Strawbridge","year":"2018"},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib84","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1176\/appi.focus.16206","article-title":"Biomarkers for depression: recent insights, current challenges and future prospects","volume":"16","author":"Strawbridge","year":"2018","journal-title":"Focus"},{"key":"10.1016\/j.nsa.2022.101014_bib85","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jad.2018.12.037","article-title":"Inflammatory profiles of severe treatment-resistant depression","volume":"246","author":"Strawbridge","year":"2019","journal-title":"J.\u00a0Affect. Disord."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib86","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1192\/bjp.2018.233","article-title":"Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis","volume":"214","author":"Strawbridge","year":"2019","journal-title":"Br. J. Psychiatry"},{"issue":"12","key":"10.1016\/j.nsa.2022.101014_bib87","doi-asserted-by":"crossref","first-page":"3918","DOI":"10.3390\/jcm9123918","article-title":"Inflammatory proteins and clinical response to psychological therapy in patients with depression: an exploratory study","volume":"9","author":"Strawbridge","year":"2020","journal-title":"J.\u00a0Clin. Med."},{"key":"10.1016\/j.nsa.2022.101014_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.pbb.2020.173073","article-title":"Bupropion monotherapy alters neurotrophic and inflammatory markers in patients of major depressive disorder","volume":"200","author":"Tafseer","year":"2021","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"11","key":"10.1016\/j.nsa.2022.101014_bib89","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1177\/0269881119872194","article-title":"Predictors of response to augmentation treatment in patients with treatment-resistant depression: a systematic review","volume":"33","author":"Taylor","year":"2019","journal-title":"J.\u00a0Psychopharmacol."},{"issue":"9","key":"10.1016\/j.nsa.2022.101014_bib90","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1093\/ijnp\/pyaa033","article-title":"Pharmacological augmentation in unipolar depression: a guide to the guidelines","volume":"23","author":"Taylor","year":"2020","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.nsa.2022.101014_bib91","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jad.2021.04.074","article-title":"Predicting clinical outcome to specialist multimodal inpatient treatment in patients with treatment resistant depression","volume":"291","author":"Taylor","year":"2021","journal-title":"J.\u00a0Affect. Disord."},{"key":"10.1016\/j.nsa.2022.101014_bib92","series-title":"The Maudsley Prescribing Guidelines in Psychiatry","first-page":"980","author":"Taylor","year":"2021"},{"key":"10.1016\/j.nsa.2022.101014_bib93","first-page":"1130","article-title":"Effect of intraocular surgery and ketamine on aqueous and serum cytokines","volume":"13","author":"Tu","year":"2007","journal-title":"Mol. Vis."},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib94","first-page":"1362","article-title":"A\u00a0study of the protective effect and mechanism of ketamine on acute lung injury induced by mechanical ventilation","volume":"21","author":"Wang","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib95","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/bja\/aeq341","article-title":"Continuous S-(+)-ketamine administration during elective coronary artery bypass graft surgery attenuates pro-inflammatory cytokine response during and after cardiopulmonary bypass","volume":"106","author":"Welters","year":"2011","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.nsa.2022.101014_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2019.107136","article-title":"Sub-anesthetic and anesthetic ketamine produce different long-lasting behavioral phenotypes (24 h post-treatment) via inducing different brain-derived neurotrophic factor (BDNF) expression level in the hippocampus","volume":"167","author":"Wu","year":"2020","journal-title":"Neurobiol. Learn. Mem."},{"issue":"2","key":"10.1016\/j.nsa.2022.101014_bib97","first-page":"134","article-title":"Effects of low-dose ketamine on perioperative cytokine response and postoperative pain in cervical cancer patients | Cochrane Library","volume":"5","author":"Xie","year":"2015","journal-title":"Anti-Tumor Pharm."},{"key":"10.1016\/j.nsa.2022.101014_bib98","article-title":"Effects of ketamine and propofol on levels of perioperative plasma cytokines in gastric cancer patients underwent radical gastrectomy","author":"Xin","year":"2006","journal-title":"J.\u00a0Jilin Univ. Ed. [Internet]"},{"issue":"6","key":"10.1016\/j.nsa.2022.101014_bib99","first-page":"802","article-title":"[Effects of subanesthetic dose of ketamine on perioperative serum cytokines in orthotopic liver transplantation]","volume":"26","author":"Yang","year":"2006","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"10.1016\/j.nsa.2022.101014_bib100","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.jad.2019.07.045","article-title":"Inflammatory markers and treatment outcome in treatment resistant depression: a systematic review","volume":"257","author":"Yang","year":"2019","journal-title":"J.\u00a0Affect. Disord."},{"issue":"1","key":"10.1016\/j.nsa.2022.101014_bib101","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/s41398-020-00933-z","article-title":"Alterations of multiple peripheral inflammatory cytokine levels after repeated ketamine infusions in major depressive disorder","volume":"10","author":"Zhan","year":"2020","journal-title":"Transl. Psychiatry"},{"issue":"276","key":"10.1016\/j.nsa.2022.101014_bib102","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jad.2020.06.068","article-title":"Relationship between hippocampal volume and inflammatory markers following six infusions of ketamine in major depressive disorder","author":"Zhou","year":"2020","journal-title":"J.\u00a0Affect. Disord."},{"key":"10.1016\/j.nsa.2022.101014_bib103","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.2147\/NDT.S106652","article-title":"Levels of serum immunomodulators and alterations with electroconvulsive therapy in treatment-resistant major depression","volume":"12","author":"Zincir","year":"2016","journal-title":"Neuropsychiatric Dis. Treat."}],"container-title":["Neuroscience Applied"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772408522010158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772408522010158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T04:34:16Z","timestamp":1731645256000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772408522010158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":103,"alternative-id":["S2772408522010158"],"URL":"https:\/\/doi.org\/10.1016\/j.nsa.2022.101014","relation":{},"ISSN":["2772-4085"],"issn-type":[{"value":"2772-4085","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral inflammatory effects of different interventions for treatment-resistant depression: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Neuroscience Applied","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nsa.2022.101014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V. on behalf of European College of Neuropsychopharmacology.","name":"copyright","label":"Copyright"}],"article-number":"101014"}}