{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:07:49Z","timestamp":1790428069320,"version":"4.1.0"},"reference-count":93,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1016\/j.ntt.2004.06.016","type":"journal-article","created":{"date-parts":[[2004,9,14]],"date-time":"2004-09-14T18:04:48Z","timestamp":1095185088000},"page":"757-768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":225,"title":["Ethanol effects on the developing zebrafish: neurobehavior and skeletal morphogenesis"],"prefix":"10.1016","volume":"26","author":[{"suffix":"III","given":"Michael J.","family":"Carvan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evyn","family":"Loucks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel N.","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick E.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2004.06.016_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1242\/dev.117.1.29","article-title":"Programmed cell death during Drosophila embryogenesis","volume":"117","author":"Abrams","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1542\/peds.106.2.358","article-title":"Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders (RE9948)","volume":"106","author":"American Academy of Pediatrics","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.ntt.2004.06.016_bib3","doi-asserted-by":"crossref","first-page":"9526","DOI":"10.1074\/jbc.271.16.9526","article-title":"Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression","volume":"271","author":"Ang","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ntt.2004.06.016_bib4","first-page":"283","article-title":"Identifying maternal self-reported alcohol use associated with fetal alcohol spectrum disorders","volume":"25","author":"Barr","year":"2001","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib5","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/jez.1402300305","article-title":"Bipartite axiation follows incomplete epiboly in zebrafish embryos treated with chemical teratogens","volume":"230","author":"Baumann","year":"1984","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.ntt.2004.06.016_bib6","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0091-3057(96)00255-9","article-title":"Teratogenic actions of ethanol in the mouse: a minireview","volume":"55","author":"Becker","year":"1996","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2004.06.016_bib7","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0892-0362(02)00319-7","article-title":"Effects of embryonic exposure to ethanol on zebrafish visual function","volume":"24","author":"Bilotta","year":"2002","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2004.06.016_bib8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1006\/dbio.1998.8995","article-title":"Ethanol impairs migration of the prechordal plate in the zebrafish embryo","volume":"201","author":"Blader","year":"1998","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ntt.2004.06.016_bib9","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/25836","article-title":"Casting an eye over cyclopia","volume":"395","author":"Blader","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ntt.2004.06.016_bib10","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1469-7793.1997.683bd.x","article-title":"Glycine receptors in cultured chick sympathetic neurons are excitatory and trigger neurotransmitter release","volume":"504","author":"Boehm","year":"1997","journal-title":"J. Physiol."},{"key":"10.1016\/j.ntt.2004.06.016_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1242\/dev.123.1.179","article-title":"Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain","volume":"123","author":"Brand","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib12","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1111\/j.1530-0277.1995.tb00960.x","article-title":"Effect of ethanol on plasma and hepatic insulin-like growth factor regulation in pregnant rats","volume":"19","author":"Breese","year":"1995","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1046\/j.1525-142X.2003.03022.x","article-title":"Comparative expression analysis of Adh3 during arthropod, urochordate, cephalochordate, and vertebrate development challenges its predicted housekeeping role","volume":"5","author":"Canestro","year":"2003","journal-title":"Evol. Dev."},{"key":"10.1016\/j.ntt.2004.06.016_bib14","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1111\/j.1530-0277.1995.tb01007.x","article-title":"Stage-dependent effects of ethanol on cranial neural crest cell development: partial basis for the phenotypic variations observed in fetal alcohol syndrome","volume":"19","author":"Cartwright","year":"1995","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib15","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1530-0277.1995.tb01519.x","article-title":"Increased cell death and reduced neural crest cell numbers in ethanol-exposed embryos: partial basis for the fetal alcohol syndrome phenotype","volume":"19","author":"Cartwright","year":"1995","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib16","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1056\/NEJM198509123131105","article-title":"Cocaine use in pregnancy","volume":"313","author":"Chasnoff","year":"1985","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ntt.2004.06.016_bib17","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/jnr.10208","article-title":"Ethanol exposure enhances cell death in the developing cerebral cortex: role of brain-derived neurotrophic factor and its signaling pathways","volume":"68","author":"Climent","year":"2002","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0892-0362(02)00324-0","article-title":"Antioxidants and fetal protection against ethanol teratogenicity: I. Review of the experimental data and implications to humans","volume":"25","author":"Cohen-Kerem","year":"2003","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2004.06.016_bib19","doi-asserted-by":"crossref","first-page":"3751","DOI":"10.1021\/bi00130a004","article-title":"The major piscine liver alcohol dehydrogenase has class-mixed properties in relation to mammalian alcohol dehydrogenases of classes I and III","volume":"31","author":"Danielsson","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.ntt.2004.06.016_bib20","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1006\/bbrc.2001.5511","article-title":"Developmental expression of alcohol dehydrogenase (ADH3) in zebrafish (Danio rerio)","volume":"286","author":"Dasmahapatra","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ntt.2004.06.016_bib21","first-page":"279","article-title":"Retinoids and the alcohol dehydrogenase gene family","volume":"71","author":"Duester","year":"1994","journal-title":"EXS"},{"key":"10.1016\/j.ntt.2004.06.016_bib22","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1111\/j.1530-0277.1998.tb03695.x","article-title":"Effects of moderate alcohol consumption on the central nervous system","volume":"22","author":"Eckardt","year":"1998","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s002130051081","article-title":"Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder","volume":"146","author":"Fahlke","year":"1999","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.ntt.2004.06.016_bib24","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1530-0277.1996.tb01051.x","article-title":"In utero exposure to ethanol alters mRNA for insulin-like growth factors and insulin-like growth factor-binding proteins in placenta and lung of fetal rats","volume":"20","author":"Fatayerji","year":"1996","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib25","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1242\/dev.123.1.229","article-title":"Neural degeneration mutants in the zebrafish, Danio rerio","volume":"123","author":"Furutani-Seiki","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib26","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1152\/jn.00596.2001","article-title":"Evidence for a widespread brain stem escape network in larval zebrafish","volume":"87","author":"Gahtan","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.ntt.2004.06.016_bib27","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1530-0277.1990.tb01196.x","article-title":"Maternal genetic effects on ethanol teratogenesis and dominance of relative embryonic resistance to malformations","volume":"14","author":"Gilliam","year":"1990","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib28","first-page":"321","article-title":"Genetic influences on brain growth restriction induced by development exposure to alcohol","volume":"10","author":"Goodlett","year":"1989","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2004.06.016_bib29","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0006-8993(02)03561-8","article-title":"Neonatal ethanol produces cerebellar deep nuclear cell loss and correlated disruption of eyeblink conditioning in adult rats","volume":"956","author":"Green","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib30","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/1029842021000010884","article-title":"Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure","volume":"4","author":"Guerri","year":"2002","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib31","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1006\/cryo.1997.2014","article-title":"New approaches for studying the permeability of fish embryos: toward successful cryopreservation","volume":"34","author":"Hagedorn","year":"1997","journal-title":"Cryobiology"},{"key":"10.1016\/j.ntt.2004.06.016_bib32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0166-4328(03)00028-7","article-title":"Children with fetal alcohol syndrome are impaired at place learning but not cued-navigation in a virtual Morris Water Task","volume":"143","author":"Hamilton","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib33","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1530-0277.2003.tb04402.x","article-title":"The role of neurotrophic factors, apoptosis-related proteins, and endogenous antioxidants in the differential temporal vulnerability of neonatal cerebellum to ethanol","volume":"27","author":"Heaton","year":"2003","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib34","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0165-3806(02)00470-4","article-title":"Effects of early postnatal ethanol intubation on GABAergic synaptic proteins","volume":"138","author":"Hsiao","year":"2002","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib35","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1126\/science.287.5455.1056","article-title":"Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome","volume":"287","author":"Ikonomidou","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ntt.2004.06.016_bib36","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1111\/j.1530-0277.1994.tb00092.x","article-title":"Effects of fetal alcohol exposure on infant reaction time","volume":"18","author":"Jacobson","year":"1994","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/arclin\/18.1.33","article-title":"Learning following prenatal alcohol exposure: Performance on verbal and visual multitrial tasks","volume":"18","author":"Kaemingk","year":"2003","journal-title":"Arch. Clin. Neuropsychol."},{"key":"10.1016\/j.ntt.2004.06.016_bib38","first-page":"115","article-title":"Lead toxicity and alterations in opioid systems","volume":"14","author":"Kitchen","year":"1993","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2004.06.016_bib39","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/tera.1420520304","article-title":"Ethanol-induced teratogenesis: Free radical damage as a possible mechanism","volume":"52","author":"Kotch","year":"1995","journal-title":"Teratology"},{"key":"10.1016\/j.ntt.2004.06.016_bib40","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/PL00000574","article-title":"Heat shock protein gene expression during embryonic development of the zebrafish","volume":"53","author":"Krone","year":"1997","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ntt.2004.06.016_bib41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/jez.1401770107","article-title":"Ethanol induced notochord and spinal cord duplications in the embryo of the zebrafish, Brachydanio rerio","volume":"177","author":"Laale","year":"1971","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.ntt.2004.06.016_bib42","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/(SICI)1520-6408(1997)21:2<123::AID-DVG2>3.0.CO;2-9","article-title":"hsp47 And hsp70 gene expression is differentially regulated in a stress- and tissue-specific manner in zebrafish embryos","volume":"21","author":"Lele","year":"1997","journal-title":"Dev. Genet."},{"key":"10.1016\/j.ntt.2004.06.016_bib43","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/brain\/awg014","article-title":"Lead neurotoxicity in children: Basic mechanisms and clinical correlates","volume":"126","author":"Lidsky","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.ntt.2004.06.016_bib44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0006-8993(01)03224-3","article-title":"Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum","volume":"924","author":"Light","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib45","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0031-9384(02)00804-1","article-title":"Maternal alcohol consumption during pregnancy and fetal startle behaviour","volume":"76","author":"Little","year":"2002","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ntt.2004.06.016_bib46","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0741-8329(00)00133-6","article-title":"Regional differences in cell loss associated with binge-like alcohol exposure during the first two trimesters equivalent in the rat","volume":"23","author":"Maier","year":"2001","journal-title":"Alcohol"},{"key":"10.1016\/j.ntt.2004.06.016_bib47","first-page":"1418","article-title":"Fetal alcohol exposure and temporal vulnerability regional differences in alcohol-induced microencephaly as a function of the timing of binge-like alcohol exposure during rat brain development","volume":"21","author":"Maier","year":"1997","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib48","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1037\/0894-4105.12.1.146","article-title":"Neuropsychological comparison of alcohol-exposed children with or without physical features of fetal alcohol syndrome","volume":"12","author":"Mattson","year":"1998","journal-title":"Neuropsychology"},{"key":"10.1016\/j.ntt.2004.06.016_bib49","first-page":"185","article-title":"Teratogenic effects of alcohol on brain and behavior","volume":"25","author":"Mattson","year":"2001","journal-title":"Alcohol Res. Health"},{"key":"10.1016\/j.ntt.2004.06.016_bib50","doi-asserted-by":"crossref","first-page":"260A","DOI":"10.1111\/j.1530-0277.1996.tb01788.x","article-title":"Supporting cells as targets of ethanol toxicity: altered regulation of growth factors and extracellular matrix","volume":"20","author":"Miller","year":"1996","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib51","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1530-0277.1996.tb01056.x","article-title":"Limited ethanol exposure selectively alters the proliferation of precursor cells in the cerebral cortex","volume":"20","author":"Miller","year":"1996","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib52","first-page":"433","article-title":"Fetal alcohol syndrome\u2014Alaska, Arizona, Colorado, and New York, 1995\u20131997","volume":"51","author":"Miller","year":"2003","journal-title":"MMWR"},{"key":"10.1016\/j.ntt.2004.06.016_bib53","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1023\/A:1021832522701","article-title":"Episodic exposure to ethanol during development differentially affects brainstem nuclei in the macaque","volume":"30","author":"Mooney","year":"2001","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.ntt.2004.06.016_bib54","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0006-8993(01)02718-4","article-title":"Effects of prenatal exposure to ethanol on the expression of bcl-2, bax and caspase 3 in the developing rat cerebral cortex and thalamus","volume":"911","author":"Mooney","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib55","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1242\/dev.123.1.357","article-title":"Mutations affecting craniofacial development in zebrafish","volume":"123","author":"Neuhauss","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib56","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s11626-998-0038-5","article-title":"MSX-1 gene expression and regulation in embryonic palatal tissue","volume":"34","author":"Nugent","year":"1998","journal-title":"In Vitro Cell. Dev. Biol., Anim."},{"key":"10.1016\/j.ntt.2004.06.016_bib57","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1750-3639.2002.tb00467.x","article-title":"Drug-induced apoptotic neurodegeneration in the developing brain","volume":"12","author":"Olney","year":"2002","journal-title":"Brain Pathol."},{"key":"10.1016\/j.ntt.2004.06.016_bib58","first-page":"1998","article-title":"Neuropsychological deficits in adolescents with fetal alcohol syndrome: clinical findings","volume":"22","author":"Olson","year":"1998","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib59","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/070674370204700405","article-title":"Clinical implications of a link between fetal alcohol spectrum disorder and attention-deficit hyperactivity disorder","volume":"47","author":"O'Malley","year":"2002","journal-title":"Can. J. Psychiatry"},{"key":"10.1016\/j.ntt.2004.06.016_bib60","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0896-6273(00)80246-9","article-title":"Imaging the functional organization of zebrafish hindbrain segments during escape behaviors","volume":"17","author":"O'Malley","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.ntt.2004.06.016_bib61","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1161\/01.RES.79.2.358","article-title":"Disruption of hemoglobin oxygen transport does not impact oxygen-dependent physiological processes in developing embryos of zebra fish (Danio rerio)","volume":"79","author":"Pelster","year":"1996","journal-title":"Circ. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib62","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1242\/dev.123.1.345","article-title":"Jaw and branchial arch mutants in zebrafish: II. Anterior arches and cartilage differentiation","volume":"123","author":"Piotrowski","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib63","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0304-3940(03)00013-2","article-title":"Effects of dietary lead and\/or dimercaptosuccinic acid exposure on regional serotonin and serotonin metabolite content in rainbow trout (Oncorhynchus mykiss)","volume":"339","author":"Rademacher","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ntt.2004.06.016_bib64","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1007\/s001289900116","article-title":"Comparative study on the synergistic and individual effects of dimecron and cuman L on oxygen uptake and haematological parameters of a freshwater edible fish, Sarotherodon mossambicus (Peters)","volume":"56","author":"Ramaswamy","year":"1996","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ntt.2004.06.016_bib65","doi-asserted-by":"crossref","first-page":"7549","DOI":"10.1073\/pnas.94.14.7549","article-title":"Gestational exposure to ethanol suppresses msx2 expression in developing mouse embryos","volume":"94","author":"Rifas","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ntt.2004.06.016_bib66","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/0887-8994(94)90012-4","article-title":"Difference in susceptibility to teratogenic effects of alcohol in discordant twins exposed to alcohol during the second half of gestation","volume":"11","author":"Riikonen","year":"1994","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.ntt.2004.06.016_bib67","doi-asserted-by":"crossref","first-page":"8956","DOI":"10.1523\/JNEUROSCI.21-22-08956.2001","article-title":"In vivo imaging of zebrafish reveals differences in the spinal networks for escape and swimming movements","volume":"21","author":"Ritter","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2004.06.016_bib68","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF02255980","article-title":"Alcohol deters the outgrowth of serotonergic neurons at midgestation","volume":"8","author":"Sari","year":"2001","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.ntt.2004.06.016_bib69","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0741-8329(95)00034-O","article-title":"Alcohol inhibits neurite extension and increases N-myc and c-myc proteins","volume":"12","author":"Saunders","year":"1995","journal-title":"Alcohol"},{"key":"10.1016\/j.ntt.2004.06.016_bib70","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1242\/dev.123.1.329","article-title":"Jaw and branchial arch mutants in zebrafish: I. Branchial arches","volume":"123","author":"Schilling","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ntt.2004.06.016_bib71","first-page":"2111","article-title":"Prenatal ethanol exposure selectively reduces the mRNA encoding alpha-1 thyroid hormone receptor in fetal rat brain","volume":"22","author":"Scott","year":"1998","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib72","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0741-8329(96)00068-7","article-title":"Effect of neonatal thyroid hormone alterations in CNS ethanol sensitivity in adult LS and SS mice","volume":"13","author":"Segall","year":"1996","journal-title":"Alcohol"},{"key":"10.1016\/j.ntt.2004.06.016_bib73","first-page":"51","article-title":"The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome","volume":"2","author":"Shean","year":"1993","journal-title":"Alcohol Alcohol., Suppl."},{"key":"10.1016\/j.ntt.2004.06.016_bib74","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00206680","article-title":"Waterborne lead affects circadian variations of brain neurotransmitters in fathead minnows","volume":"55","author":"Spieler","year":"1995","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.ntt.2004.06.016_bib75","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/j.1530-0277.1998.tb03649.x","article-title":"Neonatal ethanol exposure impairs eyeblink conditioning in weanling rats","volume":"22","author":"Stanton","year":"1998","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib76","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/ajmg.1320470612","article-title":"Fetal alcohol syndrome in twins of alcoholic mothers: Concordance of diagnosis and IQ","volume":"47","author":"Streissguth","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ntt.2004.06.016_bib77","first-page":"176","article-title":"Alcohol exposure in utero and functional deficits in children during the first four years of life","volume":"105","author":"Streissguth","year":"1984","journal-title":"Ciba Found. Symp."},{"key":"10.1016\/j.ntt.2004.06.016_bib78","first-page":"717","article-title":"Attention, distraction and reaction time at age 7 years and prenatal alcohol exposure","volume":"8","author":"Streissguth","year":"1986","journal-title":"Neurobehav. Toxicol. Teratol."},{"key":"10.1016\/j.ntt.2004.06.016_bib79","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/alcalc\/37.1.2","article-title":"Ophthalmic involvement in the fetal alcohol syndrome: clinical and animal model studies","volume":"37","author":"Stromland","year":"2002","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.ntt.2004.06.016_bib80","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1530-0277.2001.tb02128.x","article-title":"Genetic influences on craniofacial outcome in an avian model of prenatal alcohol exposure","volume":"25","author":"Su","year":"2001","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib81","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0741-8329(98)00008-1","article-title":"Neonatal alcohol exposure produces hyperactivity in high-alcohol-sensitive but not in low-alcohol-sensitive rats","volume":"16","author":"Thomas","year":"1998","journal-title":"Alcohol"},{"key":"10.1016\/j.ntt.2004.06.016_bib82","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0741-8329(99)00080-4","article-title":"Neonatal alcohol exposure produces more severe motor coordination deficits in high alcohol sensitive rats compared to low alcohol sensitive rats","volume":"20","author":"Thomas","year":"2000","journal-title":"Alcohol"},{"key":"10.1016\/j.ntt.2004.06.016_bib83","first-page":"401","article-title":"Recent studies on the effects of fetal alcohol exposure on the endocrine and immune systems","volume":"2","author":"Weinberg","year":"1994","journal-title":"Alcohol Alcohol., Suppl."},{"key":"10.1016\/j.ntt.2004.06.016_bib84","first-page":"245","article-title":"Long-term effects of developmental exposure to alcohol","volume":"7","author":"West","year":"1986","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2004.06.016_bib85","series-title":"The Zebrafish Book","author":"Westerfield","year":"2000"},{"key":"10.1016\/j.ntt.2004.06.016_bib86","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/bdrc.10010","article-title":"Revisiting the role of retinoid signaling in skeletal development","volume":"69","author":"Weston","year":"2003","journal-title":"Birth Defects Res., Part C Embryo Today"},{"key":"10.1016\/j.ntt.2004.06.016_bib87","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0376-6357(02)00025-6","article-title":"A simple spatial alternation task for assessing memory function in zebrafish","volume":"58","author":"Williams","year":"2002","journal-title":"Behav. Processes"},{"key":"10.1016\/j.ntt.2004.06.016_bib88","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/hmg\/6.3.369","article-title":"Perinatal lethality and multiple craniofacial malformations in MSX2 transgenic mice","volume":"6","author":"Winograd","year":"1997","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ntt.2004.06.016_bib89","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0009-2797(02)00167-9","article-title":"Human class IV alcohol dehydrogenase: Kinetic mechanism, functional roles and medical relevance","volume":"143\u2013144","author":"Yin","year":"2003","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.ntt.2004.06.016_bib90","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000047135","article-title":"Prenatal ethanol consumption increases retinol and cellular retinol-binding protein expression in the rat fetal snout","volume":"80","author":"Zachman","year":"2001","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.ntt.2004.06.016_bib91","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1006\/cryo.1998.2093","article-title":"Permeability of dechorionated one-cell and six-somite stage zebrafish (Brachydanio rerio) embryos to water and methanol","volume":"37","author":"Zhang","year":"1998","journal-title":"Cryobiology"},{"key":"10.1016\/j.ntt.2004.06.016_bib92","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0165-3806(00)00144-9","article-title":"Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL mice","volume":"126","author":"Zhou","year":"2001","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.ntt.2004.06.016_bib93","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-3806(03)00158-5","article-title":"Moderate alcohol exposure compromises neural tube midline development in prenatal brain","volume":"144","author":"Zhou","year":"2003","journal-title":"Brain Res. Dev. Brain Res."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036204000972?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036204000972?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:09:42Z","timestamp":1760209782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036204000972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":93,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["S0892036204000972"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2004.06.016","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2004,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ethanol effects on the developing zebrafish: neurobehavior and skeletal morphogenesis","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2004.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}