{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:54:06Z","timestamp":1789649646053,"version":"4.0.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1016\/j.ntt.2005.03.008","type":"journal-article","created":{"date-parts":[[2005,4,24]],"date-time":"2005-04-24T07:16:06Z","timestamp":1114326966000},"page":"643-653","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["Reappraisal of somatosensory disorders in methylmercury poisoning"],"prefix":"10.1016","volume":"27","author":[{"given":"Tadashi","family":"Ninomiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Imamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misako","family":"Kuwahata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiaki","family":"Kindaichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Susa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeo","family":"Ekino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2005.03.008_bib1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0048-9697(95)04905-3","article-title":"Methylmercury pollution in the Amazon, Brazil","volume":"175","author":"Akagi","year":"1995","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ntt.2005.03.008_bib2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1006\/enrs.1997.3822","article-title":"Methylmercury dose estimation from umbilical cord concentrations in patients with Minamata disease","volume":"77","author":"Akagi","year":"1998","journal-title":"Environ. Res."},{"key":"10.1016\/j.ntt.2005.03.008_bib3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0363-5023(87)80189-2","article-title":"The repeatability of testing with Semmes\u2013Weinstein monofilaments","volume":"12","author":"Bell-Krotoski","year":"1987","journal-title":"J. Hand Surg."},{"key":"10.1016\/j.ntt.2005.03.008_bib4","series-title":"Handbook on the Toxicology of Metals","first-page":"387","article-title":"Mercury","author":"Berlin","year":"1987"},{"key":"10.1016\/j.ntt.2005.03.008_bib5","first-page":"305","article-title":"Quantifying sensory loss in peripheral neuropathies","volume":"7","author":"Bleecker","year":"1985","journal-title":"Neurobehav. Toxicol. Teratol."},{"key":"10.1016\/j.ntt.2005.03.008_bib6","series-title":"Handbook of Clinical Neurology","first-page":"63","article-title":"Parietal lobe syndromes","volume":"vol. 1 (45)","author":"Botez","year":"1985"},{"key":"10.1016\/j.ntt.2005.03.008_bib7","series-title":"Neurology in Clinical Practice","first-page":"3","article-title":"Approach to the diagnosis of neurological disease","author":"Bradley","year":"1991"},{"key":"10.1016\/j.ntt.2005.03.008_bib8","series-title":"Human Neuroanatomy","author":"Carpenter","year":"1976"},{"key":"10.1016\/j.ntt.2005.03.008_bib9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1001\/archneur.1970.00480250045007","article-title":"Somatosensory thresholds","volume":"23","author":"Corkin","year":"1970","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.ntt.2005.03.008_bib10","series-title":"The Parietal Lobes","author":"Critchley","year":"1953"},{"key":"10.1016\/j.ntt.2005.03.008_bib11","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/micr.1920100214","article-title":"Comparison of two-point discrimination testing devices","volume":"10","author":"Crosby","year":"1989","journal-title":"Microsurgery"},{"key":"10.1016\/j.ntt.2005.03.008_bib12","series-title":"Handbook of Clinical Neurology","first-page":"80","article-title":"Sensation","volume":"vol. 1","author":"Dejong","year":"1969"},{"key":"10.1016\/j.ntt.2005.03.008_bib13","series-title":"The Second Report on Hair Mercury Concentration in Minamata disease","author":"Doi","year":"1962"},{"key":"10.1016\/j.ntt.2005.03.008_bib14","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF02889124","article-title":"Pathological changes of human sural nerves in Minamata disease (methylmercury poisoning). Light and electron microscopic studies","volume":"23","author":"Eto","year":"1977","journal-title":"Virchows Arch., B Pathol."},{"key":"10.1016\/j.ntt.2005.03.008_bib15","series-title":"Neurology in Clinical Practice","first-page":"299","article-title":"Sensory abnormalities of the limbs and trunk","author":"Gordon","year":"1991"},{"key":"10.1016\/j.ntt.2005.03.008_bib16","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0892-0362(97)00097-4","article-title":"Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury","volume":"19","author":"Grandjean","year":"1997","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2005.03.008_bib17","series-title":"Textbook of Medical Physiology","author":"Guyton","year":"1986"},{"key":"10.1016\/j.ntt.2005.03.008_bib18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1006\/enrs.1998.3837","article-title":"The present mercury contents of scalp hair and clinical symptoms in inhabitants of the Minamata area","volume":"77","author":"Harada","year":"1998","journal-title":"Environ. Res."},{"key":"10.1016\/j.ntt.2005.03.008_bib19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0048-9697(99)00255-7","article-title":"Methylmercury level in umbilical cords from patients with congenital Minamata disease","volume":"234","author":"Harada","year":"1999","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ntt.2005.03.008_bib20","series-title":"StatView","author":"Haycock","year":"1992"},{"key":"10.1016\/j.ntt.2005.03.008_bib21","first-page":"193","article-title":"Poisoning by methyl mercury compounds","volume":"9","author":"Hunter","year":"1940","journal-title":"Q. J. Med."},{"key":"10.1016\/j.ntt.2005.03.008_bib22","first-page":"392","article-title":"Studies on the origin of causative agent of Minamata disease report VIII. On the formation of methylmercury compounds in an acetaldehyde plant. Methyl mercury compounds formed from the reaction of acetaldehyde and inorganic mercury compounds","volume":"22","author":"Irukayama","year":"1967","journal-title":"Japanese Journal of Hygiene"},{"key":"10.1016\/j.ntt.2005.03.008_bib23","first-page":"200","article-title":"Japanese Association of Public Health, environmental pollution by mercury in Japan","volume":"23","author":"Japanese Association of Public Health","year":"1973","journal-title":"Environ. Health Rep."},{"key":"10.1016\/j.ntt.2005.03.008_bib24","series-title":"Principles of Neural Science","first-page":"367","article-title":"Touch","author":"Kandel","year":"1991"},{"key":"10.1016\/j.ntt.2005.03.008_bib25","first-page":"370","article-title":"Minamata disease. The outbreak of a neurologic disorder in Minamata, Japan, and its relationship to the ingestion of seafood contaminated by mercuric compounds","volume":"1","author":"Kurland","year":"1960","journal-title":"World Neurol."},{"key":"10.1016\/j.ntt.2005.03.008_bib26","series-title":"Merritt's Textbook of Neurology","first-page":"648","article-title":"Peripheral Neuropathies. General Considerations","author":"Latov","year":"1995"},{"key":"10.1016\/j.ntt.2005.03.008_bib27","first-page":"157","article-title":"Evidence of early nervous system dysfunction in Amazonian populations exposed to low-levels of methylmercury","volume":"17","author":"Lebel","year":"1996","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2005.03.008_bib28","series-title":"Peripheral Neuropathy","first-page":"2162","article-title":"Neuropathy due to drugs","author":"Le Quesne","year":"1984"},{"key":"10.1016\/j.ntt.2005.03.008_bib29","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0363-5023(84)80109-4","article-title":"Evaluation of normal values for stationary and moving two-point discrimination in the hand","volume":"9","author":"Louis","year":"1984","journal-title":"J. Hand Surg."},{"key":"10.1016\/j.ntt.2005.03.008_bib30","series-title":"Fundamentals of Anatomy and Physiology","author":"Martini","year":"2001"},{"key":"10.1016\/j.ntt.2005.03.008_bib31","doi-asserted-by":"crossref","first-page":"270","DOI":"10.2337\/diacare.12.4.270","article-title":"Measuring diabetic neuropathy. Assessment and comparison of clinical examination and quantitative sensory testing","volume":"12","author":"Maser","year":"1989","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ntt.2005.03.008_bib32","series-title":"Bing's Local Diagnosis in Neurological Diseases","first-page":"234","article-title":"Localization of lesions involving the trigeminal nerve","author":"Mehler","year":"1969"},{"key":"10.1016\/j.ntt.2005.03.008_bib33","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF00690559","article-title":"Late changes in human sural nerves in Minamata disease and in nerves of rats with experimental organic poisoning","volume":"35","author":"Miyakawa","year":"1976","journal-title":"Acta. Neuropathol. (Berl.)"},{"key":"10.1016\/j.ntt.2005.03.008_bib34","first-page":"88","article-title":"Electrophysiologic and histopathologic studies on sural nerves from Minamata disease patients of delayed onset showing distal sensory impairments","volume":"25","author":"Nagaki","year":"1985","journal-title":"Clin. Neurol."},{"key":"10.1016\/j.ntt.2005.03.008_bib35","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1006\/enrs.1995.1045","article-title":"Expansion of methylmercury poisoning outside of Minamata: an epidemiological study on chronic methylmercury poisoning outside of Minamata","volume":"70","author":"Ninomiya","year":"1995","journal-title":"Environ. Res."},{"key":"10.1016\/j.ntt.2005.03.008_bib36","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/258324a0","article-title":"Methylmercury and selenium in umbilical cords of inhabitants of the Minamata area","volume":"258","author":"Nishigaki","year":"1975","journal-title":"Nature"},{"key":"10.1016\/j.ntt.2005.03.008_bib37","first-page":"139","article-title":"Sensory and cognitive effects of developmental methylmercury exposure in monkeys, and a comparison to effects in rodents","volume":"17","author":"Rice","year":"1996","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2005.03.008_bib38","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/brain\/97.1.499","article-title":"Methyl mercury poisoning in Iraq. A neurological study","volume":"97","author":"Rustam","year":"1974","journal-title":"Brain"},{"key":"10.1016\/j.ntt.2005.03.008_bib39","series-title":"Peripheral Neuropathy","first-page":"2115","article-title":"Human toxic neuropathy due to industrial agents","author":"Schaumburg","year":"1984"},{"key":"10.1016\/j.ntt.2005.03.008_bib40","series-title":"Somatosensory Changes after Penetrating Brain Wounds in Man","author":"Semmes","year":"1960"},{"key":"10.1016\/j.ntt.2005.03.008_bib41","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/geronj\/47.1.P35","article-title":"Aging and spatial acuity of touch","volume":"47","author":"Stevens","year":"1992","journal-title":"J. Gerontol."},{"key":"10.1016\/j.ntt.2005.03.008_bib42","series-title":"Minamata Disease","author":"Study Group of Minamata Disease","year":"1968"},{"key":"10.1016\/j.ntt.2005.03.008_bib43","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1093\/ije\/14.4.582","article-title":"Mortality and survival for Minamata disease","volume":"14","author":"Tamashiro","year":"1985","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.ntt.2005.03.008_bib44","series-title":"Peripheral Neuropathy","first-page":"1169","article-title":"Symptomatology and differential diagnosis of peripheral neuropathy, clinical features and differential diagnosis","author":"Thomas","year":"1984"},{"key":"10.1016\/j.ntt.2005.03.008_bib45","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1212\/WNL.32.12.1369","article-title":"Minamata disease (organic mercury poisoning): neuroradiologic and electrophysiologic studies","volume":"32","author":"Tokuomi","year":"1982","journal-title":"Neurology"},{"key":"10.1016\/j.ntt.2005.03.008_bib46","series-title":"Global Mercury Assessment","author":"UNEP Chemicals","year":"2002"},{"key":"10.1016\/j.ntt.2005.03.008_bib47","series-title":"Harrison's Principles of Internal Medicine Seventh Edition","first-page":"110","article-title":"Disorders of sensation. Sensory loss due to lesion in the parietal lobe","author":"Victor","year":"1974"},{"key":"10.1016\/j.ntt.2005.03.008_bib48","series-title":"The Cytoarchitectonics of the Human Cerebral Cortex","author":"von Economo","year":"1929"},{"key":"10.1016\/j.ntt.2005.03.008_bib49","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/S0140-6736(01)06466-2","article-title":"Mercury poisoning victims could increase by 20,000","volume":"358","author":"Watts","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.ntt.2005.03.008_bib50","series-title":"Handbook of Clinical Neurology","first-page":"41","article-title":"Conduction properties and pathophysiology of myelinated and non-myelinated nerve fibers","volume":"vol. 7 (51)","author":"Waxman","year":"1987"},{"key":"10.1016\/j.ntt.2005.03.008_bib51","series-title":"The Sense of Touch","first-page":"19","author":"Weber","year":"1978"},{"key":"10.1016\/j.ntt.2005.03.008_bib52","series-title":"The Skin Senses","first-page":"195","article-title":"Intensive and extensive aspects of tactile sensitivity as a function of body part, sex, and laterality","author":"Weinstein","year":"1968"},{"key":"10.1016\/j.ntt.2005.03.008_bib53","series-title":"Environmental Health Criteria: 1. Mercury","author":"WHO","year":"1976"},{"key":"10.1016\/j.ntt.2005.03.008_bib54","series-title":"Environmental Health Criteria 101: Methylmercury","author":"WHO","year":"1990"},{"key":"10.1016\/j.ntt.2005.03.008_bib55","first-page":"263","article-title":"Peripheral neuropathy due to chemical and industrial exposure","volume":"vol. 7 (51)","author":"Windebank","year":"1987"},{"key":"10.1016\/j.ntt.2005.03.008_bib56","series-title":"Peripheral Neuropathy","first-page":"2133","article-title":"Metal neuropathy","author":"Windebank","year":"1984"},{"key":"10.1016\/j.ntt.2005.03.008_bib57","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1248\/jhs.50.120","article-title":"Current hair mercury levels in Japanese for estimation of methylmercury exposure","volume":"50","author":"Yasutake","year":"2004","journal-title":"J. Health Sci."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036205000498?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036205000498?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:10:36Z","timestamp":1760209836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036205000498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0892036205000498"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2005.03.008","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reappraisal of somatosensory disorders in methylmercury poisoning","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2005.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}