{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:24:05Z","timestamp":1791221045839,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.ntt.2006.11.010","type":"journal-article","created":{"date-parts":[[2006,12,7]],"date-time":"2006-12-07T13:04:38Z","timestamp":1165496678000},"page":"116-125","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["1H MRS-detectable metabolic brain changes and reduced impulsive behavior in adult rats exposed to methylphenidate during adolescence"],"prefix":"10.1016","volume":"29","author":[{"given":"W.","family":"Adriani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Canese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Podo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Laviola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2006.11.010_bib1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s00213-004-1892-9","article-title":"Acetyl-l-carnitine reduces impulsive behaviour in adolescent rats","volume":"176","author":"Adriani","year":"2004","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1471-2202-7-52","article-title":"Delay aversion but preference for binge and rare rewards in two choice tasks: implications for measuring of self-control parameters","volume":"7","author":"Adriani","year":"2006","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib3","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1038\/sj.npp.1300962","article-title":"Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression","volume":"31","author":"Adriani","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0165-0173(00)00038-2","article-title":"CNS energy metabolism as related to function","volume":"34","author":"Ames","year":"2000","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.ntt.2006.11.010_bib5","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/cercor\/10.10.1014","article-title":"Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: implications for the development of psycho-pathology","volume":"10","author":"Benes","year":"2000","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.ntt.2006.11.010_bib6","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/S0006-3223(03)00570-5","article-title":"Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood","volume":"54","author":"Bolanos","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ntt.2006.11.010_bib7","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0893-133X(01)00281-0","article-title":"Enhanced reactivity and vulnerability to cocaine following methylphenidate treatment in adolescent rats","volume":"25","author":"Brandon","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2202-6-9","article-title":"Nucleus accumbens core lesions retard instrumental learning and performance with delayed reinforcement in the rat","volume":"6","author":"Cardinal","year":"2005","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib9","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1126\/science.1060818","article-title":"Impulsive choice induced in rats by lesions of the nucleus accumbens core","volume":"292","author":"Cardinal","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.ntt.2006.11.010_bib10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1196\/annals.1308.004","article-title":"Limbic corticostriatal systems and delayed reinforcement","volume":"1021","author":"Cardinal","year":"2004","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.ntt.2006.11.010_bib11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neuropharm.2004.06.021","article-title":"Understanding the neurobiological consequences of early exposure to psychotropic drugs: linking behavior with molecules","volume":"47","author":"Carlezon","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib12","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.biopsych.2003.08.020","article-title":"Enduring behavioral effects of early exposure to methylphenidate in rats","volume":"54","author":"Carlezon","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ntt.2006.11.010_bib13","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/00002826-200307000-00013","article-title":"Metabolite changes resulting from treatment in children with ADHD: a 1H-MRS study","volume":"26","author":"Carrey","year":"2003","journal-title":"Clin. Neuropharmacol."},{"key":"10.1016\/j.ntt.2006.11.010_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1034\/j.1600-0404.2000.00303.x","article-title":"Magnetic resonance spectroscopy in Alzheimer's disease: focus on N-acetylaspartate","volume":"176","author":"Chen","year":"2000","journal-title":"Acta. Neurol. Scand. Suppl."},{"key":"10.1016\/j.ntt.2006.11.010_bib15","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1046\/j.1460-9568.2002.02223.x","article-title":"Long-lasting enhancement of corticostriatal neurotransmission by taurine","volume":"16","author":"Chepkova","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib16","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1037\/0735-7044.115.4.812","article-title":"Functional disconnection of a prefrontal cortical-dorsal striatal system disrupts choice reaction time performance: implications for attentional function","volume":"115","author":"Christakou","year":"2001","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib17","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1523\/JNEUROSCI.0949-03.2004","article-title":"Prefrontal cortical-ventral striatal interactions involved in affective modulation of attentional performance: implications for corticostriatal circuit function","volume":"24","author":"Christakou","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib18","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1176\/jnp.16.1.63","article-title":"Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings","volume":"16","author":"Courvoisie","year":"2004","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib19","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S0893-133X(01)00412-2","article-title":"Deficits in impulse control associated with tonically-elevated serotonergic function in rat prefrontal cortex","volume":"26","author":"Dalley","year":"2002","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib20","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1111\/j.1460-9568.2004.03309.x","article-title":"Role of taurine uptake on the induction of long-term synaptic potentiation","volume":"19","author":"del Olmo","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib21","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/PL00005481","article-title":"Varieties of impulsivity","volume":"146","author":"Evenden","year":"1999","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib22","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/PL00005486","article-title":"The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement","volume":"146","author":"Evenden","year":"1999","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib23","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.acra.2005.01.016","article-title":"Comparative study of cerebral white matter in autism and attention-deficit\/hyperactivity disorder by means of magnetic resonance spectroscopy","volume":"12","author":"Fayed","year":"2005","journal-title":"Acad. Radiol."},{"key":"10.1016\/j.ntt.2006.11.010_bib24","series-title":"NMR and Its Applications to Living Systems","author":"Gadian","year":"1995"},{"key":"10.1016\/j.ntt.2006.11.010_bib25","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.neuropharm.2004.11.015","article-title":"Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression","volume":"48","author":"Guscott","year":"2005","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib26","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/1098-2779(2000)6:3<214::AID-MRDD9>3.0.CO;2-M","article-title":"Attention-deficit\/hyperactivity disorder: perspectives from neuroimaging","volume":"6","author":"Hale","year":"2000","journal-title":"Ment. Retard. Dev. Disabil. Res. Rev."},{"key":"10.1016\/j.ntt.2006.11.010_bib27","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s002130050410","article-title":"Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: Interactions with dopaminergic mechanisms","volume":"133","author":"Harrison","year":"1997","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib28","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.tips.2004.07.002","article-title":"Functional, molecular and pharmacological advances in 5-HT7 receptor research","volume":"25","author":"Hedlund","year":"2004","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ntt.2006.11.010_bib29","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0304-3940(01)01730-X","article-title":"Attention-deficit disorder in adults with or without hyperactivity: where is the difference? A study in humans using short echo (1)H-magnetic resonance spectroscopy","volume":"304","author":"Hessinger","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ntt.2006.11.010_bib30","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1901\/jaba.2006.171-04","article-title":"A computerized test of self-control predicts classroom behavior","volume":"39","author":"Hoerger","year":"2006","journal-title":"J. Appl. Behav. Anal."},{"key":"10.1016\/j.ntt.2006.11.010_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0304-3940(01)02315-1","article-title":"Striatal neural loss or dysfunction and choline rise in children with attention-deficit hyperactivity disorder: a proton magnetic resonance spectroscopy study","volume":"315","author":"Jin","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ntt.2006.11.010_bib32","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0730-725X(98)00118-0","article-title":"Absolute metabolite quantification by in vivo NMR spectroscopy: II a multicentre trial of protocols for in vivo localised proton studies of human brain","volume":"16","author":"Keevil","year":"1998","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.ntt.2006.11.010_bib33","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1023\/B:NERE.0000010433.08577.96","article-title":"Regulation of the cellular content of the organic osmolyte taurine in mammalian cells","volume":"29","author":"Lambert","year":"2004","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.ntt.2006.11.010_bib34","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1602\/neurorx.2.2.197","article-title":"Efficacy of proton magnetic resonance spectroscopy in neurological diagnosis and neurotherapeutic decision making","volume":"2","author":"Lin","year":"2005","journal-title":"NeuroRx"},{"key":"10.1016\/j.ntt.2006.11.010_bib35","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0006-3223(02)01401-4","article-title":"Proton spectroscopy in medication-free pediatric attention-deficit\/hyperactivity disorder","volume":"53","author":"MacMaster","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ntt.2006.11.010_bib36","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1126\/science.1100907","article-title":"Separate neural systems value immediate and delayed monetary rewards","volume":"306","author":"McClure","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.ntt.2006.11.010_bib37","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1017\/S1461145705005845","article-title":"Exposure to amphetamine in rats during periadolescence establishes behavioural and extrastriatal neural sensitization in adulthood","volume":"9","author":"McPherson","year":"2006","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.ntt.2006.11.010_bib38","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neuropharm.2004.06.031","article-title":"Molecular mechanisms of drug addiction","volume":"47","author":"Nestler","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib39","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/mrm.1910300604","article-title":"Estimation of metabolite concentrations from localized in vivo proton NMR spectra","volume":"30","author":"Provencher","year":"2003","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.ntt.2006.11.010_bib40","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1074-7427(03)00077-7","article-title":"Acetylcholine actions in the dorsomedial striatum support the flexible shifting of response patterns","volume":"80","author":"Ragozzino","year":"2003","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.ntt.2006.11.010_bib41","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.bandc.2004.09.016","article-title":"Neurocognitive mechanisms of cognitive control: the role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning","volume":"56","author":"Ridderinkhof","year":"2004","journal-title":"Brain Cogn."},{"key":"10.1016\/j.ntt.2006.11.010_bib42","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.neuropharm.2004.06.025","article-title":"Structural plasticity associated with exposure to drugs of abuse","volume":"47","author":"Robinson","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib43","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1037\/0735-7044.115.4.799","article-title":"Lesions of the medial and lateral striatum in the rat produce dissociable deficits in attentional performance","volume":"115","author":"Rogers","year":"2001","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib44","first-page":"1","article-title":"Attention deficit\/hyperactivity disorder \u2014 from brain dysfunction to behavior","volume":"94","author":"Sagvolden","year":"1998","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ntt.2006.11.010_bib45","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.coph.2004.09.004","article-title":"Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine","volume":"5","author":"Salamone","year":"2005","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.ntt.2006.11.010_bib46","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1016\/j.neuropsychologia.2005.10.012","article-title":"Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptoms","volume":"44","author":"Scheres","year":"2006","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.ntt.2006.11.010_bib47","doi-asserted-by":"crossref","first-page":"S356","DOI":"10.1139\/y92-283","article-title":"Role of taurine in neural cell volume regulation","volume":"70","author":"Schousboe","year":"1992","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.ntt.2006.11.010_bib48","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0378-1097(03)00611-6","article-title":"Taurine: new implications for an old amino acid","volume":"226","author":"Schuller-Levis","year":"2003","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.ntt.2006.11.010_bib49","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1523\/JNEUROSCI.18-07-02613.1998","article-title":"Neuronal signals in the monkey ventral striatum related to progress through a predictable series of trials","volume":"18","author":"Shidara","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib50","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.neubiorev.2003.08.005","article-title":"The dual pathway model of AD\/HD: an elaboration of neuro-developmental characteristics","volume":"27","author":"Sonuga-Barke","year":"2003","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ntt.2006.11.010_bib51","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.biopsych.2004.09.008","article-title":"Causal models of attention-deficit\/hyperactivity disorder: from common simple deficits to multiple developmental pathways","volume":"57","author":"Sonuga-Barke","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ntt.2006.11.010_bib52","first-page":"173","article-title":"Proton magnetic resonance spectroscopy and cognitive function in pediatric attention-deficit\/hyperactive disorder","volume":"54","author":"Sparkes","year":"2004","journal-title":"Brain Cogn."},{"key":"10.1016\/j.ntt.2006.11.010_bib53","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.braindev.2004.09.004","article-title":"Differences between attention-deficit disorder with and without hyperactivity: a 1H-magnetic resonance spectroscopy study","volume":"27","author":"Sun","year":"2005","journal-title":"Brain Dev."},{"key":"10.1016\/j.ntt.2006.11.010_bib54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0959-4388(98)80150-5","article-title":"Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder","volume":"8","author":"Swanson","year":"1998","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.ntt.2006.11.010_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0166-4328(01)00433-8","article-title":"Pharmacokinetic and pharmacodynamic properties of stimulants: implications for the design of new treatments for ADHD","volume":"130","author":"Swanson","year":"2002","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ntt.2006.11.010_bib56","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0165-3806(95)00109-Q","article-title":"Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens","volume":"89","author":"Teicher","year":"1995","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.ntt.2006.11.010_bib57","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1037\/0735-7036.114.4.325","article-title":"Attractivity and social preferences in mice (Mus musculus domesticus): the role of prepubertal sexual segregation and of precocious weaning","volume":"114","author":"Terranova","year":"2000","journal-title":"J. Comp. Psychol."},{"key":"10.1016\/j.ntt.2006.11.010_bib58","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s00213-005-2221-7","article-title":"Repeated administration of methylphenidate in young, adolescent, and mature rats affects the response to cocaine later in adulthood","volume":"181","author":"Torres-Reveron","year":"2005","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2006.11.010_bib59","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/1469-7610.00764","article-title":"Sensitivity to reward delay in children with attention deficit hyperactivity disorder (ADHD)","volume":"42","author":"Tripp","year":"2001","journal-title":"J. Child Psychol. Psychiatry"},{"key":"10.1016\/j.ntt.2006.11.010_bib60","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/00004583-200303000-00010","article-title":"Proton magnetic resonance spectroscopy investigation of the right frontal lobe in children with attention-deficit\/hyperactivity disorder","volume":"43","author":"Yeo","year":"2003","journal-title":"J. Am. Acad. Child Adolesc. Psych."},{"key":"10.1016\/j.ntt.2006.11.010_bib61","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1460-9568.2004.03095.x","article-title":"Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning","volume":"19","author":"Yin","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ntt.2006.11.010_bib62","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/(SICI)1098-2302(199703)30:2<141::AID-DEV5>3.0.CO;2-Q","article-title":"Multiparous species present problems (and possibilities) to the developmentalists","volume":"30","author":"Zorrilla","year":"1997","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.ntt.2006.11.010_bib63","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neuint.2005.04.003","article-title":"An update on the role of brain glutamine synthesis and its relation to cell-specific energy metabolism in the hyperammonemic brain: further studies using NMR spectroscopy","volume":"47","author":"Zwingmann","year":"2005","journal-title":"Neurochem. Int."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036206001863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036206001863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:12:01Z","timestamp":1760209921000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036206001863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S0892036206001863"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2006.11.010","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"1H MRS-detectable metabolic brain changes and reduced impulsive behavior in adult rats exposed to methylphenidate during adolescence","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2006.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}