{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:17:41Z","timestamp":1760242661780,"version":"build-2065373602"},"reference-count":73,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1016\/j.ntt.2009.08.001","type":"journal-article","created":{"date-parts":[[2009,8,10]],"date-time":"2009-08-10T05:13:53Z","timestamp":1249881233000},"page":"400-405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Perinatal exposure to alcohol reduces the expression of complexins I and II"],"prefix":"10.1016","volume":"31","author":[{"given":"Mathias","family":"Zink","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclsemin","family":"Ara\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie Th.","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Gass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Gebicke-H\u00e4rter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Spanagel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2009.08.001_bib1","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1097\/01.alc.0000187806.68957.0a","article-title":"Prenatal ethanol exposure in rats decreases levels of complexin proteins in the frontal cortex","volume":"29","author":"Barr","year":"2005","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib2","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1471-4159.2008.05685.x","article-title":"Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons","volume":"107","author":"Basavarajappa","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ntt.2009.08.001_bib3","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1002\/pmic.200400848","article-title":"Proteome analysis of human substantia nigra in Parkinson's disease","volume":"4","author":"Basso","year":"2004","journal-title":"Proteomics"},{"key":"10.1016\/j.ntt.2009.08.001_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/(SICI)1098-2396(199901)31:1<51::AID-SYN7>3.0.CO;2-O","article-title":"Ethanol exposure during the third trimester equivalent results in long-lasting decreased synaptic efficacy but not plasticity in the CA1 region of the rat hippocampus","volume":"31","author":"Bellinger","year":"1999","journal-title":"Synapse"},{"key":"10.1016\/j.ntt.2009.08.001_bib5","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0165-3806(02)00363-2","article-title":"Neonatal ethanol exposure reduces AMPA but not NMDA receptor levels in the rat neocortex","volume":"1","author":"Bellinger","year":"2002","journal-title":"Develop Brain Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib6","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/(SICI)1098-1063(2000)10:1<94::AID-HIPO11>3.0.CO;2-T","article-title":"Effects of prenatal alcohol exposure on the hippocampus: spatial behavior, electrophysiology, and neuroanatomy","volume":"10","author":"Berman","year":"2000","journal-title":"Hippocampus"},{"key":"10.1016\/j.ntt.2009.08.001_bib7","first-page":"39","article-title":"Postnatal development of alcohol dehydrogenase in liver and intestine of rats exposed to ethanol in utero","volume":"121","author":"Bhalla","year":"2005","journal-title":"Indian J. Med. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/13556210410001717088","article-title":"Increased sibling mortality in children with fetal alcohol syndrome","volume":"9","author":"Burd","year":"2004","journal-title":"Add. Biol."},{"key":"10.1016\/j.ntt.2009.08.001_bib9","doi-asserted-by":"crossref","first-page":"19538","DOI":"10.1073\/pnas.0810232105","article-title":"Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming","volume":"105","author":"Cai","year":"2008","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ntt.2009.08.001_bib10","doi-asserted-by":"crossref","first-page":"19962","DOI":"10.1073\/pnas.0807758105","article-title":"Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling","volume":"105","author":"Chen","year":"2008","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ntt.2009.08.001_bib11","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1097\/01.ALC.0000171040.82077.E","article-title":"Short-term memory impairment and reduced hippocampal c-Fos expression in an animal model of fetal alcohol syndrome","volume":"29","author":"Clements","year":"2005","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib12","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1080\/15287390490515001","article-title":"Differential gene profiles in developing embryo and fetus after in utero exposure to ethanol","volume":"67","author":"Da","year":"2004","journal-title":"J. Toxicol Environment Health Part A"},{"key":"10.1016\/j.ntt.2009.08.001_bib13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0165-0173(01)00067-4","article-title":"Applications of the Morris water maze in the study of learning and memory","volume":"36","author":"D'Hooge","year":"2001","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.ntt.2009.08.001_bib14","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0304-3940(94)90618-1","article-title":"Age and strain differences in rat place learning and hippocampal dentate gyrus frequency-potentiation","volume":"171","author":"Diana","year":"1994","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ntt.2009.08.001_bib15","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s11068-004-0514-8","article-title":"Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements","volume":"33","author":"DiProspero","year":"2004","journal-title":"J. Neurocytol"},{"key":"10.1016\/j.ntt.2009.08.001_bib16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-3782(79)90022-7","article-title":"Comparative aspects of the brain growth spurt","volume":"3","author":"Dobbing","year":"1979","journal-title":"Early Hum Develop"},{"key":"10.1016\/j.ntt.2009.08.001_bib17","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/sj.mp.4000741","article-title":"Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs","volume":"5","author":"Eastwood","year":"2000","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ntt.2009.08.001_bib18","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0361-9230(01)00530-5","article-title":"Synaptic pathology in the anterior cingulate cortex in schizophrenia and mood disorders. A review and a Western blot study of synaptophysin, GAP-43 and the complexins","volume":"55","author":"Eastwood","year":"2001","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ntt.2009.08.001_bib19","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.ajog.2005.05.052","article-title":"Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome","volume":"193","author":"Endres","year":"2005","journal-title":"Am. J. Obstetr. Gynecol."},{"key":"10.1016\/j.ntt.2009.08.001_bib20","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.brainresbull.2003.12.004","article-title":"Regional and progressive changes in brain expression of complexin II in a mouse transgenic for the Huntington's disease mutation","volume":"63","author":"Freeman","year":"2004","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ntt.2009.08.001_bib21","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1111\/j.1471-4159.2005.03294.x","article-title":"Alcohol is a potent stimulant of immature neuronal networks: implications for fetal alcohol spectrum disorder","volume":"94","author":"Galindo","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ntt.2009.08.001_bib22","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1126\/science.1129450","article-title":"A clamping mechanism involved in SNARE-dependent exocytosis","volume":"313","author":"Giraudo","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.ntt.2009.08.001_bib23","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1126\/science.1166500","article-title":"Alternative zippering as an on\u2013off switch for SNARE-mediated fusion","volume":"323","author":"Giraudo","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.ntt.2009.08.001_bib24","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1093\/hmg\/ddg249","article-title":"Complexin II is essential for normal neurological function in mice","volume":"12","author":"Glynn","year":"2003","journal-title":"Hum. Mol. Gen."},{"key":"10.1016\/j.ntt.2009.08.001_bib25","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1093\/hmg\/ddi239","article-title":"Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits","volume":"14","author":"Glynn","year":"2005","journal-title":"Hum. Mol. Gen."},{"key":"10.1016\/j.ntt.2009.08.001_bib26","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.nbd.2006.10.011","article-title":"Early motor development is abnormal in complexin 1 knockout mice","volume":"25","author":"Glynn","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.ntt.2009.08.001_bib27","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1006\/nlme.1995.0009","article-title":"Sex differences in vulnerability to developmental spatial learning deficits induced by limited binge alcohol exposure in neonatal rats","volume":"64","author":"Goodlett","year":"1995","journal-title":"Neurobiol Learning Memory"},{"key":"10.1016\/j.ntt.2009.08.001_bib28","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1111\/j.1530-0277.1997.tb04246.x","article-title":"Binge-like alcohol exposure of neonatal rats via intragastric intubation induces both Purkinje cell loss and cortical astrogliosis","volume":"21","author":"Goodlett","year":"1997","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib29","first-page":"193","article-title":"The effect of ethanol on the distribution of synaptic vesicles in cortical synaptosomes of the rat","volume":"27","author":"Hajos","year":"1979","journal-title":"Acta. Morphol. Acad. Scient. Hung."},{"key":"10.1016\/j.ntt.2009.08.001_bib30","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1002\/jnr.20278","article-title":"Downregulation of complexin I and complexin II in the medial thalamus is blocked by N-acetylcysteine in experimental Wernicke's encephalopathy","volume":"79","author":"Hazell","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib31","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.ntt.2007.06.001","article-title":"Statistical issues and techniques appropriate for developmental neurotoxicity testing: a report from the ILSI Research Foundation\/Risk Science Institute expert working group on neurodevelopmental endpoints","volume":"30","author":"Holson","year":"2008","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2009.08.001_bib32","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1037\/0735-7044.111.5.985","article-title":"Object-recognition and spatial learning and memory in rats prenatally exposed to ethanol","volume":"111","author":"Kim","year":"1997","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib33","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1471-4159.2003.01873.x","article-title":"Repeated variable prenatal stress alters pre- and postsynaptic gene expression in the rat frontal pole","volume":"86","author":"Kinnunen","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ntt.2009.08.001_bib34","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1111\/j.1530-0277.2007.00528.x","article-title":"Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure","volume":"31","author":"Klintsova","year":"2007","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib35","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/sj.mp.4001471","article-title":"Stanley Neuropathology Consortium. Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium","volume":"9","author":"Knable","year":"2004","journal-title":"Mol. Psychiatry."},{"key":"10.1016\/j.ntt.2009.08.001_bib36","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/01.ALC.0000086065.06203.DD","article-title":"Long-term influence of an initial exposure to alcohol on the rat hypothalamic-pituitary axis","volume":"27","author":"Lee","year":"2003","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib37","first-page":"110","article-title":"Prolonged exposure to intermittent alcohol vapors blunts hypothalamic responsiveness to immune and non-immune signals","volume":"24","author":"Lee","year":"2000","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib38","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1006\/mcne.2000.0890","article-title":"Increased activity of the hypothalamic-pituitary-adrenal axis of rats exposed to alcohol in utero: role of altered pituitary and hypothalamic function","volume":"16","author":"Lee","year":"2000","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib39","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/j.1530-0277.2003.tb04421.x","article-title":"Prenatal ethanol exposure alters the responsiveness of the rat hypothalamic-pituitary-adrenal axis to nitric oxide","volume":"27","author":"Lee","year":"2003","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib40","first-page":"401","article-title":"Chronic prenatal ethanol exposure does not affect the expression of selected genes in rat brain development","volume":"28","author":"Maciejewski-Lenoir","year":"1993","journal-title":"Alcohol Alcoholism"},{"key":"10.1016\/j.ntt.2009.08.001_bib41","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/01.ALC.0000106304.39174.AD","article-title":"Ethanol selectively inhibits enhanced vesicular release at excitatory synapses: real-time visualization in intact hippocampal slices","volume":"28","author":"Maldve","year":"2004","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib42","doi-asserted-by":"crossref","first-page":"8027","DOI":"10.1523\/JNEUROSCI.2434-05.2005","article-title":"Developmentally regulated actions of alcohol on hippocampal glutamatergic transmission","volume":"25","author":"Mameli","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib43","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1460-9568.2006.04597.x","article-title":"Alcohol increases efficacy of immature synapses in a neurosteroid-dependent manner","volume":"23","author":"Mameli","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib44","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0166-2236(02)02207-5","article-title":"Sealed with a twist: complexin and the synaptic SNARE complex","volume":"25","author":"Marz","year":"2002","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib45","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1126\/science.1166505","article-title":"Complexin controls the force transfer from SNARE complexes to membranes in fusion","volume":"323","author":"Maximov","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.ntt.2009.08.001_bib46","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0092-8674(95)90239-2","article-title":"Complexins: cytosolic proteins that regulate SNAP receptor function","volume":"83","author":"McMahon","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.ntt.2009.08.001_bib47","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0091-3057(95)02035-7","article-title":"Spatial learning in rats exposed to acute ethanol intoxication on gestational day 8","volume":"53","author":"Minetti","year":"1996","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2009.08.001_bib48","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1530-0277.2006.00266.x","article-title":"Effects of ethanol on excitatory and inhibitory synaptic transmission in rat cortical neurons","volume":"31","author":"Moriguchi","year":"2007","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib49","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-0270(84)90007-4","article-title":"Developments of a water-maze procedure for studying spatial learning in the rat","volume":"11","author":"Morris","year":"1984","journal-title":"J. Neurosci. Meth."},{"key":"10.1016\/j.ntt.2009.08.001_bib50","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0361-9230(01)00611-6","article-title":"Abnormalities in the synaptic vesicle fusion machinery in Huntington's disease","volume":"56","author":"Morton","year":"2001","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ntt.2009.08.001_bib51","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/mrdd.1037","article-title":"Glutamate signaling and the fetal alcohol syndrome","volume":"7","author":"Olney","year":"2001","journal-title":"Ment. Retard Develop Disabilities Res. Rev."},{"key":"10.1016\/j.ntt.2009.08.001_bib52","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/07853890252953509","article-title":"The enigma of fetal alcohol neurotoxicity","volume":"34","author":"Olney","year":"2002","journal-title":"Ann. Med."},{"year":"1994","author":"Paxinos","series-title":"Atlas of the developing rat nervous system; second edition","key":"10.1016\/j.ntt.2009.08.001_bib53"},{"key":"10.1016\/j.ntt.2009.08.001_bib54","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1046\/j.1471-4159.1998.71052104.x","article-title":"Prenatal ethanol exposure decreases GAP-43 phosphorylation and protein kinase C activity in the hippocampus of adult rat offspring","volume":"71","author":"Perrone-Bizzozero","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ntt.2009.08.001_bib55","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0092-8674(01)00192-1","article-title":"Complexins regulate a late step in Ca2+ -dependent neurotransmitter release","volume":"104","author":"Reim","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.ntt.2009.08.001_bib56","first-page":"106","article-title":"Effect of Repeated Exposure to Alcohol on the Response of the Hypothalamic-Pituitary-Adrenal Axis of the Rat: II. Role of the Length and Regimen of Alcohol Treatment","volume":"25","author":"Rivier","year":"2001","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib57","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1530-0277.1995.tb01583.x","article-title":"Exposure of neonatal rats to alcohol by vapor inhalation demonstrates specificity of microcephaly and Purkinje cell loss but not astrogliosis","volume":"19","author":"Ryabinin","year":"1995","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib58","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/syn.20492","article-title":"Regulation of complexin 1 and complexin 2 in the developing human prefrontal cortex","volume":"62","author":"Salimi","year":"2008","journal-title":"Synapse"},{"key":"10.1016\/j.ntt.2009.08.001_bib59","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1111\/j.1530-0277.2002.tb02480.x","article-title":"Dose-dependent effects of prenatal ethanol exposure on synaptic plasticity and learning in mature offspring","volume":"26","author":"Savage","year":"2002","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib60","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/sj.mp.4000978","article-title":"Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness","volume":"7","author":"Sawada","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ntt.2009.08.001_bib61","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1001\/archpsyc.62.3.263","article-title":"Hippocampal complexin proteins and cognitive dysfunction in schizophrenia","volume":"62","author":"Sawada","year":"2005","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.ntt.2009.08.001_bib62","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1111\/j.1471-4159.2005.03461.x","article-title":"Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1","volume":"95","author":"Siegenthaler","year":"2005","journal-title":"J. Neurochem"},{"key":"10.1016\/j.ntt.2009.08.001_bib63","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1146\/annurev.neuro.26.041002.131412","article-title":"The synaptic vesicle cycle","volume":"27","author":"Sudhof","year":"2004","journal-title":"Ann Rev Neurosci"},{"key":"10.1016\/j.ntt.2009.08.001_bib64","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.neuron.2008.10.011","article-title":"Understanding synapses: past, present, and future","volume":"60","author":"Sudhof","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.ntt.2009.08.001_bib65","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1177\/15353702-0323006-04","article-title":"Genesis of alcohol-induced craniofacial dysmorphism","volume":"230","author":"Sulik","year":"2005","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.ntt.2009.08.001_bib66","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1046\/j.1460-9568.1999.00652.x","article-title":"Reduced hippocampal LTP in mice lacking a presynaptic protein: complexin II","volume":"11","author":"Takahashi","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib67","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.cell.2006.08.030","article-title":"A complexin\/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis","volume":"126","author":"Tang","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.ntt.2009.08.001_bib68","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/01.ALC.0000106308.50817.B3","article-title":"Fetal alcohol exposure alters GAP-43 phosphorylation and protein kinase C responses to contextual fear conditioning in the hippocampus of adult rat offspring","volume":"28","author":"Tanner","year":"2004","journal-title":"Alcohol Clin. Exp. Res."},{"key":"10.1016\/j.ntt.2009.08.001_bib69","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/bjp.2008.30","article-title":"Neuropharmacology of alcohol addiction","volume":"154","author":"Vengeliene","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ntt.2009.08.001_bib70","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.nbd.2004.08.006","article-title":"Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning\/memory deficits in juveniles followed by progressive functional recovery in adults","volume":"17","author":"Wozniak","year":"2004","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.ntt.2009.08.001_bib71","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0306-4522(99)00104-9","article-title":"Immunohistochemical distribution of the two isoforms of synaphin\/complexin involved in neurotransmitter release: localization at the distinct central nervous system regions and synaptic types","volume":"93","author":"Yamada","year":"1999","journal-title":"Neurosci."},{"key":"10.1016\/j.ntt.2009.08.001_bib72","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1007\/s00213-005-0017-4","article-title":"Antidepressants differentially affect expression of complexin I and II RNA in rat hippocampus","volume":"181","author":"Zink","year":"2005","journal-title":"Psychopharmacol"},{"key":"10.1016\/j.ntt.2009.08.001_bib73","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.brainres.2007.01.066","article-title":"Reduced complexin expression in rats bred for learned helplessness","volume":"1144","author":"Zink","year":"2007","journal-title":"Brain Res."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036209001470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036209001470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:14:47Z","timestamp":1760210087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036209001470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":73,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S0892036209001470"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2009.08.001","relation":{},"ISSN":["0892-0362"],"issn-type":[{"type":"print","value":"0892-0362"}],"subject":[],"published":{"date-parts":[[2009,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perinatal exposure to alcohol reduces the expression of complexins I and II","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2009.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}