{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:23:02Z","timestamp":1777501382954,"version":"3.51.4"},"reference-count":56,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.ntt.2009.11.002","type":"journal-article","created":{"date-parts":[[2009,11,28]],"date-time":"2009-11-28T04:35:22Z","timestamp":1259382922000},"page":"187-192","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of in utero exposure to Tityus bahiensis scorpion venom in adult rats"],"prefix":"10.1016","volume":"32","author":[{"given":"Ana Leticia Coronado","family":"Dorce","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valquiria Abr\u00e3o Coronado","family":"Dorce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Leonor Abrah\u00e3o","family":"Nencioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2009.11.002_bib1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0031-9384(91)90538-Y","article-title":"Effects of maternal stress during pregnancy on forced swimming test behavior of the offspring","volume":"50","author":"Alonso","year":"1991","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib2","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.brainresbull.2008.02.033","article-title":"Developmental effects of Tityus serrulatus scorpion venom on the rat offspring","volume":"76","author":"Bar\u00e3o","year":"2008","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ntt.2009.11.002_bib3","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1590\/S1678-91992008000200010","article-title":"Embryotoxic effects of maternal exposure to Tityus serrulatus scorpion venom","volume":"14","author":"Bar\u00e3o","year":"2008","journal-title":"J. Venom Anim. Toxins incl. Trop. Dis."},{"key":"10.1016\/j.ntt.2009.11.002_bib4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0301-0082(03)00112-6","article-title":"Hippocampal modulation of sensorimotor processes","volume":"70","author":"Bast","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ntt.2009.11.002_bib5","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1590\/S1678-91992007000100007","article-title":"Scorpion envenomation symptoms in pregnant women","volume":"1","author":"Ben Nasr","year":"2007","journal-title":"J. Venom Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.ntt.2009.11.002_bib6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF00492211","article-title":"Effects of abrupt and gradual withdrawal from long-term haloperidol treatment and open field behavior of rats","volume":"65","author":"Bernardi","year":"1979","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2009.11.002_bib7","doi-asserted-by":"crossref","first-page":"3778","DOI":"10.1210\/en.2003-1759","article-title":"Sexually dimorphic effects of prenatal stress on cognition, hormonal responses, and central neurotransmitters","volume":"145","author":"Bowman","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.ntt.2009.11.002_bib8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.brainresbull.2009.02.008","article-title":"Attenuating effects of testosterone on depressive-like behavior in the forced swim test in healthy male rats","volume":"79","author":"Buddenberg","year":"2009","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ntt.2009.11.002_bib9","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.actatropica.2008.05.021","article-title":"Epidemiology of scorpionism: a global appraisal","volume":"107","author":"Chippaux","year":"2008","journal-title":"Acta Trop."},{"key":"10.1016\/j.ntt.2009.11.002_bib10","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.reprotox.2008.04.011","article-title":"Reproductive toxic effects of Tityus serrulatus scorpion venom in the rat","volume":"25","author":"Cruttenden","year":"2008","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.ntt.2009.11.002_bib11","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0091-3057(94)00314-9","article-title":"Neonatally administered naltrexone affects several behavioral responses in adult rats of both genders","volume":"50","author":"de la Vega","year":"1995","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib12","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1378\/chest.118.2.503","article-title":"Proinflammatory cytokines","volume":"118","author":"Dinarello","year":"2000","journal-title":"Chest"},{"key":"10.1016\/j.ntt.2009.11.002_bib13","doi-asserted-by":"crossref","unstructured":"A.L.C. Dorce, R.G. Bellot, V.A.C. Dorce, A.L.A. Nencioni, Effects of prenatal exposure to Tityus bahiensis scorpion venom on rat offspring development, Reprod. Toxicol., doi:10.1016\/j.reprotox.2009.04.008.","DOI":"10.1016\/j.reprotox.2009.04.008"},{"key":"10.1016\/j.ntt.2009.11.002_bib14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0924-977X(98)00032-7","article-title":"Prenatal stress induces body weight deficit and behavioural alterations in rats: the effects of diazepam","volume":"9","author":"Drago","year":"1999","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.ntt.2009.11.002_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/(SICI)1099-1263(199701)17:1<63::AID-JAT396>3.0.CO;2-M","article-title":"Effects of long-term administration of stobadine on exploratory behaviour and on striatal levels of dopamine and serotonin in rats and their offspring","volume":"17","author":"Dubovicky","year":"1997","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.ntt.2009.11.002_bib16","doi-asserted-by":"crossref","first-page":"8656","DOI":"10.1523\/JNEUROSCI.19-19-08656.1999","article-title":"High corticosterone levels in prenatally stressed rats predict persistent paradoxical sleep alterations","volume":"19","author":"Dugovic","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2009.11.002_bib17","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0031-9384(94)00228-W","article-title":"Maternal behavior of dams treated with ACTH during pregnancy","volume":"57","author":"Fameli","year":"1995","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib18","series-title":"Natural Toxins","first-page":"139","article-title":"Pathophysiology and treatment of scorpion poisoning","author":"Freire-Maia","year":"1989"},{"key":"10.1016\/j.ntt.2009.11.002_bib19","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroscience.2006.04.046","article-title":"Differential effects of prenatal stress on the morphological maturation of hippocampal neurons","volume":"141","author":"Fujioka","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.ntt.2009.11.002_bib20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0041-0101(02)00208-8","article-title":"Increased plasma levels of IL-1\u03b2, Il-6, IL-8, Il-10 and TNF-\u03b1 in patients moderately or severely envenomed by Tityus serrulatus scorpion sting","volume":"41","author":"Fukuhara","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jneumeth.2004.09.017","article-title":"Behavioral analysis during the forced swimming test using a joystick device","volume":"143","author":"Gersner","year":"2005","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.ntt.2009.11.002_bib22","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.neuropharm.2004.12.023","article-title":"Specific neurodevelopmental damage in mice offspring following maternal inflammation during pregnancy","volume":"48","author":"Golan","year":"2005","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ntt.2009.11.002_bib23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0028-2243(93)90189-J","article-title":"Effects of chronic intermittent stress on rat pregnancy and postnatal development","volume":"51","author":"Guo","year":"1993","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.ntt.2009.11.002_bib24","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2826.1994.tb00591.x","article-title":"Prenatal stress increases the hypothalamo\u2013pituitary\u2013adrenal axis response in young and adult rats","volume":"6","author":"Henry","year":"1994","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.ntt.2009.11.002_bib25","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ntt.2005.03.006","article-title":"Behavioral deficits in adult rats treated neonatally with glutamate","volume":"27","author":"Hlinak","year":"2005","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2009.11.002_bib26","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/0041-0101(95)00005-7","article-title":"The scorpion envenoming syndrome","volume":"33","author":"Ismail","year":"1995","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib27","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0041-0101(83)90002-8","article-title":"Teratogenicity in the rat of the venom from the scorpion Androctonus amoreuxi","volume":"21","author":"Ismail","year":"1983","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib28","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0041-0101(73)90146-3","article-title":"Pharmacological studies of the venom from the scorpion Buthus minax L. Koch","volume":"11","author":"Ismail","year":"1973","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0041-0101(74)90102-0","article-title":"Some pharmacological studies with scorpion (Pandinus exitialis) venom","volume":"12","author":"Ismail","year":"1974","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib30","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ijdevneu.2007.08.017","article-title":"The effects of maternal inflammation on neuronal development: possible mechanisms","volume":"25","author":"Jonakait","year":"2007","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.ntt.2009.11.002_bib31","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0091-3057(99)00167-7","article-title":"Gender differences in brain and behavior: hormonal and neuronal bases","volume":"64","author":"Kelly","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib32","doi-asserted-by":"crossref","first-page":"11032","DOI":"10.1073\/pnas.97.20.11032","article-title":"Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus","volume":"97","author":"Lemaire","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ntt.2009.11.002_bib33","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1523\/JNEUROSCI.15-01-00110.1995","article-title":"Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress","volume":"15","author":"Maccari","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2009.11.002_bib34","series-title":"Principles and Methods of Toxicology","first-page":"311","article-title":"Test methods for assessing female reproductive and developmental toxicology","author":"Manson","year":"1989"},{"key":"10.1016\/j.ntt.2009.11.002_bib35","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-3806(94)00153-Q","article-title":"Sex-specific effects of prenatal stress on hypothalamic\u2013pituitary\u2013adrenal responses to stress and brain glucocorticoid receptor density in adult rats","volume":"84","author":"McCormick","year":"1995","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib36","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0165-0173(90)90011-C","article-title":"Physiological and pathophysiological roles of excitatory amino acids during central nervous system development","volume":"15","author":"McDonald","year":"1990","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.ntt.2009.11.002_bib37","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1126\/science.6719121","article-title":"Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat","volume":"244","author":"McGivern","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.ntt.2009.11.002_bib38","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1530\/jrf.0.0990283","article-title":"Sex differences in plasma corticosterone in mouse fetuses are mediated by differential placental transport from the mother and eliminated by maternal adrenalectomy or stress","volume":"99","author":"Montano","year":"1993","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.ntt.2009.11.002_bib39","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/S0006-8993(03)03293-1","article-title":"Prenatal stress in rats predicts immobility behavior in the forced swim test. Effects of a chronic treatment with tianeptine","volume":"989","author":"Morley-Fletcher","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib40","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0031-9384(97)00462-9","article-title":"Sudden darkness induces a high activity-low anxiety state in male and female rats","volume":"63","author":"Nasello","year":"1998","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib41","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0041-0101(72)90059-1","article-title":"Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus","volume":"10","author":"Osman","year":"1972","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib42","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.devbrainres.2005.09.010","article-title":"Effects of prenatal stress on anxiety and social interactions in adult rats","volume":"160","author":"Patin","year":"2005","journal-title":"Dev. Brain Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib43","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0091-3057(86)90552-6","article-title":"Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus maze: a novel test of anxiety in the rat","volume":"24","author":"Pellow","year":"1986","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2009.11.002_bib44","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.toxicon.2007.06.001","article-title":"Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages","volume":"50","author":"Petricevich","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.ntt.2009.11.002_bib45","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1677\/joe.0.1000301","article-title":"Effects of stress administered during pregnancy on reproductive capacity and subsequent development of the offspring of rats: prolonged effects on the litters of a second pregnancy","volume":"100","author":"Pollard","year":"1984","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ntt.2009.11.002_bib46","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression: a new animal model sensitive to antidepressant treatments","volume":"266","author":"Porsolt","year":"1977","journal-title":"Nature."},{"key":"10.1016\/j.ntt.2009.11.002_bib47","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.bbr.2004.03.010","article-title":"Further evidences that risk assessment and object exploration behaviours are useful to evaluate emotional reactivity in rodents","volume":"154","author":"Roy","year":"2004","journal-title":"Behav Brain Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib48","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.1210\/en.2004-0742","article-title":"Prenatal exposure to interleukin-6 results in hypertension and increased hypothalamic\u2013pituitary\u2013adrenal axis activity in adult rats","volume":"145","author":"Samuelsson","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.ntt.2009.11.002_bib49","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0163-6383(92)80009-J","article-title":"The effect of mild stress during pregnancy on birth-weight and neuromotor maturation in rhesus-monkey infants (Macaca mulatta)","volume":"15","author":"Schneider","year":"1992","journal-title":"Infant Behav. Dev."},{"key":"10.1016\/j.ntt.2009.11.002_bib50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/1467-8624.00020","article-title":"Growth and development following prenatal stress exposure in primates: an examination of ontogenetic vulnerability","volume":"70","author":"Schneider","year":"1999","journal-title":"Child Dev."},{"key":"10.1016\/j.ntt.2009.11.002_bib51","first-page":"117","article-title":"The plus-maze discriminative avoidance task: a new model to study memory anxiety interactions","volume":"102","author":"Silva","year":"2000","journal-title":"Effects of chlordiazepoxide and caffeine. J. Neurosci. Methods"},{"key":"10.1016\/j.ntt.2009.11.002_bib52","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.neures.2004.05.010","article-title":"Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: implication in psychiatric disorders of developmental origin","volume":"50","author":"Tohmi","year":"2004","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib53","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0301-0082(01)00018-1","article-title":"Alterations induced by gestational stress in brain morphology and behavior of the offspring","volume":"65","author":"Weinstock","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ntt.2009.11.002_bib54","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1007\/s11064-007-9339-4","article-title":"Gender differences in the effects of prenatal stress on brain development and behavior","volume":"32","author":"Weinstock","year":"2007","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib55","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0006-8993(92)91049-K","article-title":"Prenatal stress selectively alters the reactivity of the hypothalamic\u2013pituitary\u2013adrenal system in female rat","volume":"595","author":"Weinstock","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2009.11.002_bib56","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.bbr.2006.09.003","article-title":"Maternal adrenal hormone secretion mediates behavioural alterations induced by prenatal stress in male and female rats","volume":"175","author":"Zagron","year":"2006","journal-title":"Behav. Brain Res."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036209001962?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036209001962?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:15:43Z","timestamp":1760210143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036209001962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0892036209001962"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2009.11.002","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of in utero exposure to Tityus bahiensis scorpion venom in adult rats","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2009.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}