{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:52:32Z","timestamp":1789872752255,"version":"4.0.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.ntt.2013.03.002","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T22:32:43Z","timestamp":1364855563000},"page":"57-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Astrogliosis and HSP 70 activation in neonate rats' brain exposed to sodium metavanadate through lactation"],"prefix":"10.1016","volume":"37","author":[{"given":"Santiago","family":"Cuesta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramiro","family":"Proietto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graciela Beatriz","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2013.03.002_bb0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.talanta.2006.12.015","article-title":"Determination of vanadium in petroleum and petroleum products using atomic spectrometric techniques","volume":"72","author":"Amorim","year":"2007","journal-title":"Talanta"},{"key":"10.1016\/j.ntt.2013.03.002_bb0020","doi-asserted-by":"crossref","first-page":"9689","DOI":"10.1016\/S0021-9258(19)50145-4","article-title":"S100\u03b2 stimulates calcium fluxes in glial, and neuronal cells","volume":"267","author":"Barger","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1016\/j.ntt.2013.03.002_bb0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.neures.2011.06.004","article-title":"Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury","volume":"71","author":"Barreto","year":"2011","journal-title":"Neurosci Res"},{"key":"10.1016\/j.ntt.2013.03.002_bb0030","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/neu.480230410","article-title":"S100 is present in developing chicken neurons, and Schwann cells, and promotes neuron survival in vivo","volume":"23","author":"Bhattacharyya","year":"1992","journal-title":"J Neurobiol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0035","first-page":"1","article-title":"Variability in the embryotoxicity and fetotoxicity of vanadate with the day of exposure","volume":"35","author":"Bosque","year":"1993","journal-title":"Vet Hum Toxicol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0040","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein\u2013dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.ntt.2013.03.002_bb0045","author":"Byczkowski"},{"key":"10.1016\/j.ntt.2013.03.002_bb0050","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1080\/01926230390226645","article-title":"DNA damage in nasal and brain tissues of canines exposed to air-pollutants is associated with evidence of chronic brain inflammation and neurodegeneration","volume":"31","author":"Calderon Garcidue\u00f1as","year":"2003","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0055","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0013-9351(82)90027-5","article-title":"Assessment of teratogenicity of ammonium vanadate using Syrian golden hamsters","volume":"29","author":"Carlton","year":"1982","journal-title":"Environ Res"},{"key":"10.1016\/j.ntt.2013.03.002_bb0060","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1046\/j.1471-4159.2001.00374.x","article-title":"Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism","volume":"77","author":"Chen","year":"2001","journal-title":"J Neurochem"},{"key":"10.1016\/j.ntt.2013.03.002_bb0065","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ntt.2010.10.010","article-title":"ROS formation and antioxidant status in brain areas of rats exposed to sodium metavanadate","volume":"33","author":"Cuesta","year":"2011","journal-title":"Neurotoxicol Teratol"},{"issue":"1","key":"10.1016\/j.ntt.2013.03.002_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00024382-199901000-00001","article-title":"Heat shock proteins: facts, thoughts and dreams","volume":"11","author":"De Maio","year":"1999","journal-title":"Shock"},{"key":"10.1016\/j.ntt.2013.03.002_bb0080","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/0024-3205(86)90460-1","article-title":"Effects of vanadium on reproduction, gestation, parturition and lactation in rats upon oral administration","volume":"39","author":"Domingo","year":"1986","journal-title":"Life Sci"},{"key":"10.1016\/j.ntt.2013.03.002_bb0085","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1139\/y85-037","article-title":"Vanadium exposure enhances lipid peroxidation in the kidney of rats and mice","volume":"63","author":"Donaldson","year":"1985","journal-title":"Can J Physiol Pharmacol"},{"issue":"3","key":"10.1016\/j.ntt.2013.03.002_bb0090","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF02916615","article-title":"Vanadium transport across placenta and milk of rats to the fetus and newborn","volume":"22","author":"Edel","year":"1989","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.ntt.2013.03.002_bb0095","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/BF02795686","article-title":"Sodium vanadate toxicity in adult and developing rats. Role of peroxidative damage","volume":"14","author":"Elfant","year":"1987","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.ntt.2013.03.002_bb0100","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S1040-8428(01)00221-9","article-title":"Vanadium in cancer treatment","volume":"42","author":"Evangelou","year":"2002","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0105","first-page":"1","article-title":"Vanadium inhalation in a mouse model for the understanding of air-suspended particle systemic repercussion","volume":"2011","author":"Fortoul","year":"2011","journal-title":"J Biomed Biotechnol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1081\/DCT-120037747","article-title":"Morphological alterations of central nervous system (CNS) myelin in vanadium (V) exposed adult rats","volume":"27","author":"Garcia","year":"2004","journal-title":"Drug Chem Toxicol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0110","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1081\/DCT-200064496","article-title":"Vanadium (v)-induced neurotoxicity in the rat central nervous system: a histo-immunohistochemical study","volume":"28","author":"Garcia","year":"2005","journal-title":"Drug Chem Toxicol"},{"issue":"2","key":"10.1016\/j.ntt.2013.03.002_bb0120","first-page":"103","article-title":"Ultrastructural localization of S 100 protein in reactive astrocytes","volume":"9","author":"Gomez","year":"1990","journal-title":"Commun Biol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0125","series-title":"Current protocols in neuroscience","article-title":"Measurement of oxygen radicals and lipid peroxidation in neural tissues","author":"Hall","year":"2000"},{"key":"10.1016\/j.ntt.2013.03.002_bb0130","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/glia.20411","article-title":"TGF-b1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS-2","volume":"54","author":"Hamby","year":"2006","journal-title":"Glia"},{"issue":"3","key":"10.1016\/j.ntt.2013.03.002_bb0135","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/0091-3057(80)90254-3","article-title":"A rapid method for the regional dissection of the rat brain","volume":"13","author":"Heffner","year":"1980","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.ntt.2013.03.002_bb0140","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1073\/pnas.88.7.2811","article-title":"Neuronal NADPH-diaphorase is a nitric oxide synthase","volume":"88","author":"Hope","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ntt.2013.03.002_bb0150","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1046\/j.1471-4159.1997.69062294.x","article-title":"S100\u03b2 induces neuronal cell death through nitric oxide release from astrocytes","volume":"69","author":"Hu","year":"1997","journal-title":"J Neurochem"},{"key":"10.1016\/j.ntt.2013.03.002_bb0145","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1074\/jbc.271.5.2543","article-title":"S100\u03b2 stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes","volume":"271","author":"Hu","year":"1996","journal-title":"J Biol Chem"},{"issue":"3","key":"10.1016\/j.ntt.2013.03.002_bb0155","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3233\/JAD-2009-1075","article-title":"Glial fibrillary acidic protein and protein S-100B: different concentration pattern of glial proteins in cerebrospinal fluid of patients with Alzheimer's disease and Creutzfeldt\u2013Jakob disease","volume":"17","author":"Jesse","year":"2009","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.ntt.2013.03.002_bb0160","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1080\/08958370590912914","article-title":"Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice, VIII, source-related daily variations in in vitro responses to CAPs","volume":"17","author":"Maciejczyk","year":"2005","journal-title":"Inhal Toxicol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0170","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0300-483X(00)00306-1","article-title":"Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology","volume":"153","author":"Mates","year":"2000","journal-title":"Toxicology"},{"key":"10.1016\/j.ntt.2013.03.002_bb0175","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0304-3940(93)90673-9","article-title":"A correlation between soluble brain nitric oxide synthase and NADPH-diaphorase activity is only seen after exposure of the tissue to fixative","volume":"155","author":"Matsumoto","year":"1993","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.ntt.2013.03.002_bb0165","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/0046-8177(95)90001-2","article-title":"Glial cytokines in Alzheimer's disease: review and pathogenic implications","volume":"26","author":"Mrak","year":"1995","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0180","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.toxlet.2004.01.009","article-title":"Vanadium an element of atypical biological significance","volume":"150","author":"Mukherjee","year":"2004","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.ntt.2013.03.002_bb0185","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1097\/00004647-200007000-00003","article-title":"High susceptibility to cerebral ischemia in GFAP-null mice","volume":"20","author":"Nawashiro","year":"2000","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.ntt.2013.03.002_bb0200","first-page":"19","article-title":"The use of glial fibrillary acidic protein in first-tier assessments of neurotoxicity","volume":"10","author":"O'Callaghan","year":"1991","journal-title":"J Am Coll Toxicol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0195","first-page":"195","article-title":"Quantitative features of reactive gliosis following toxicant-induced damage of the CNS","volume":"679","author":"O'Callaghan","year":"1993"},{"issue":"2","key":"10.1016\/j.ntt.2013.03.002_bb0205","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0361-9230(00)00325-7","article-title":"Roles of molecular chaperones in the nervous system","volume":"53","author":"Ohtsuka","year":"2000","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.ntt.2013.03.002_bb0210","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/biof.5520170124","article-title":"Molecular chaperones, stress proteins and redox homeostasis","volume":"17","author":"Papp","year":"2003","journal-title":"Biofactors"},{"key":"10.1016\/j.ntt.2013.03.002_bb0220","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/jat.2550100307","article-title":"Developmental toxicity of vanadium in mice after oral administration","volume":"10","author":"Paternain","year":"1990","journal-title":"J Appl Toxicol"},{"issue":"4","key":"10.1016\/j.ntt.2013.03.002_bb0225","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1006\/phrs.2000.0788","article-title":"Behavioral and developmental outcomes of prenatal and postnatal vanadium exposure in the rat","volume":"43","author":"Poggioli","year":"2001","journal-title":"Pharmacol Res"},{"issue":"1","key":"10.1016\/j.ntt.2013.03.002_bb0230","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/019262330002800113","article-title":"Stress proteins as molecular markers of neurotoxicity","volume":"28","author":"Rajdev","year":"2000","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0235","first-page":"415","article-title":"Lipid peroxidation and antioxidant enzymes in vanadate-treated rats","volume":"307C","author":"Russanov","year":"1994","journal-title":"Comp Biochem Physiol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0240","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF02991416","article-title":"Developmental toxicity evaluation of orthovanadate in the mouse","volume":"30","author":"Sanchez","year":"1991","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.ntt.2013.03.002_bb0245","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/00005072-199201000-00008","article-title":"Regional differentiation of the human fetal ependyma: immunocytochemical markers","volume":"51","author":"Sarnat","year":"1992","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0250","first-page":"413","article-title":"Microchromatographic analysis of lipids, protein, and occurrence of lipid peroxidation in various brain areas of vanadium exposed rats: a possible mechanism of vanadium neurotoxicity","volume":"15","author":"Sasi","year":"1994","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2013.03.002_bb0255","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1523\/JNEUROSCI.23-08-03394.2003","article-title":"Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress","volume":"23","author":"Shih","year":"2003","journal-title":"J Neurosci"},{"issue":"4","key":"10.1016\/j.ntt.2013.03.002_bb0260","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ntt.2007.03.001","article-title":"Vanadium exposure through lactation produces behavioural alterations and CNS myelin deficit in neonatal rats","volume":"29","author":"Soazo","year":"2007","journal-title":"Neurotoxicol Teratol"},{"issue":"12","key":"10.1016\/j.ntt.2013.03.002_bb0265","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.tins.2009.08.002","article-title":"Molecular dissection of reactive astrogliosis and glial scar formation","volume":"32","author":"Sofroniew","year":"2009","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.ntt.2013.03.002_bb0270","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/18.5.315","article-title":"The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen\u2013antibody complex (horseradish peroxidase\u2013antihorseradish peroxidase) and its use in identification of spirochetes","volume":"28","author":"Sternberger","year":"1970","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.ntt.2013.03.002_bb0275","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2174\/1566524043479185","article-title":"Astrocyte influences on ischemic neuronal death","volume":"4","author":"Swanson","year":"2004","journal-title":"Curr Mol Med"},{"key":"10.1016\/j.ntt.2013.03.002_bb0280","doi-asserted-by":"crossref","first-page":"13574","DOI":"10.1523\/JNEUROSCI.4099-08.2008","article-title":"Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis","volume":"28","author":"Vargas","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.ntt.2013.03.002_bb0290","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0301-0082(94)90023-X","article-title":"Nitric oxide: a radical neurotransmitter in the central nervous system","volume":"42","author":"Vincent","year":"1994","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.ntt.2013.03.002_bb0285","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/0306-4522(92)90184-4","article-title":"Histochemical mapping of nitric oxide synthase in the rat brain","volume":"46","author":"Vincent","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/j.ntt.2013.03.002_bb0295","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1053\/meta.2001.23294","article-title":"Effect of vanadium on insulin sensitivity and appetite","volume":"50","author":"Wang","year":"2001","journal-title":"Metabolism"},{"key":"10.1016\/j.ntt.2013.03.002_bb0300","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0300-483X(91)90178-4","article-title":"Vanadate-induced toxicity towards isolated perfused rat livers: the role of lipid peroxidation","volume":"66","author":"Younes","year":"1991","journal-title":"Toxicology"}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036213000573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036213000573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:18:42Z","timestamp":1760210322000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036213000573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":55,"alternative-id":["S0892036213000573"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2013.03.002","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Astrogliosis and HSP 70 activation in neonate rats' brain exposed to sodium metavanadate through lactation","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2013.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}