{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T17:52:26Z","timestamp":1768413146530,"version":"3.49.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"National Institute of Environmental Health Sciences and Environmental Protection Agency","award":["R01 ES015517"],"award-info":[{"award-number":["R01 ES015517"]}]},{"name":"National Institute of Environmental Health Sciences and Environmental Protection Agency","award":["P01 ES11261"],"award-info":[{"award-number":["P01 ES11261"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.ntt.2016.02.002","type":"journal-article","created":{"date-parts":[[2016,2,13]],"date-time":"2016-02-13T16:31:02Z","timestamp":1455381062000},"page":"61-67","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Low-level gestational exposure to mercury and maternal fish consumption: Associations with neurobehavior in early infancy"],"prefix":"10.1016","volume":"54","author":[{"given":"Yingying","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane C.","family":"Khoury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi","family":"Sucharew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4458-0516","authenticated-orcid":false,"given":"Kimberly","family":"Yolton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ntt.2016.02.002_bb0005","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations","volume":"6","author":"Baron","year":"1986","journal-title":"J. Pers. Soc. Psychol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0010","series-title":"BDI-II, Beck Depression Inventory: Manual","author":"Beck","year":"1996"},{"key":"10.1016\/j.ntt.2016.02.002_bb0015","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3945\/ajcn.110.000323","article-title":"Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age","volume":"5","author":"Boucher","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ntt.2016.02.002_bb0020","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1289\/ehp.1206323","article-title":"Domain-specific effects of prenatal exposure to PCBs, mercury, and lead on infant cognition: results from the Environmental Contaminants and Child Development Study in Nunavik","volume":"3","author":"Boucher","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2016.02.002_bb0025","doi-asserted-by":"crossref","first-page":"1880S","DOI":"10.3945\/ajcn.110.001107","article-title":"Effects of prenatal fish-oil and 5-methyltetrahydrofolate supplementation on cognitive development of children at 6.5y of age","volume":"6 Suppl","author":"Campoy","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ntt.2016.02.002_bb0030","series-title":"Whole Blood Lead, Cadmium and Mercury Determined Using Inductively Coupled Plasma Mass Spectrometry, DLS Method Code: 2003-01\/OD. CLIA Methods","author":"CDC","year":"2003"},{"key":"10.1016\/j.ntt.2016.02.002_bb0035","series-title":"Fourth National Report on Human Exposure to Environmental Chemicals","author":"CDC","year":"2009"},{"key":"10.1016\/j.ntt.2016.02.002_bb0040","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1111\/j.1467-8624.2004.00737.x","article-title":"Maternal DHA and the development of attention in infancy and toddlerhood","volume":"4","author":"Colombo","year":"2004","journal-title":"Child Dev."},{"key":"10.1016\/j.ntt.2016.02.002_bb0045","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/01.ede.0000129514.46451.ce","article-title":"Fish intake during pregnancy and early cognitive development of offspring","volume":"4","author":"Daniels","year":"2004","journal-title":"Epidemiology"},{"key":"10.1016\/j.ntt.2016.02.002_bb0050","unstructured":"Davidson PW, Myers GJ, Cox C, Shamlaye CF, Marsh DO, Tanner MA, Berlin M, Sloane-Reeves J, Cernichiari E, Choisy O and others. Longitudinal neurodevelopmental study of Seychellois children following in utero exposure to methylmercury from maternal fish ingestion: outcomes at 19 and 29months. Neurotoxicology 1995; 4: 677\u201388."},{"key":"10.1016\/j.ntt.2016.02.002_bb0055","doi-asserted-by":"crossref","unstructured":"Davidson PW, Myers GJ, Cox C, Axtell C, Shamlaye C, Sloane-Reeves J, Cernichiari E, Needham L, Choi A, Wang Y and others. Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66months of age in the Seychelles Child Development Study. JAMA 1998; 8: 701\u20137.","DOI":"10.1001\/jama.280.8.701"},{"key":"10.1016\/j.ntt.2016.02.002_bb0060","doi-asserted-by":"crossref","unstructured":"Davidson PW, Cory-Slechta DA, Thurston SW, Huang LS, Shamlaye CF, Gunzler D, Watson G, van Wijngaarden E, Zareba G, Klein JD and others. Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17years from the Seychelles child development study. Neurotoxicology 2011; 6: 711\u20137.","DOI":"10.1016\/j.neuro.2011.08.003"},{"key":"10.1016\/j.ntt.2016.02.002_bb0065","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.ntt.2006.02.005","article-title":"Impact of prenatal methylmercury exposure on neurobehavioral function at age 14years","volume":"5","author":"Debes","year":"2006","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0070","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.cortex.2015.05.017","article-title":"Cognitive deficits at age 22years associated with prenatal exposure to methylmercury","volume":"74","author":"Debes","year":"2016","journal-title":"Cortex"},{"key":"10.1016\/j.ntt.2016.02.002_bb0075","doi-asserted-by":"crossref","first-page":"F45","DOI":"10.1136\/adc.2006.099085","article-title":"Cognitive assessment of children at age 2(1\/2) years after maternal fish oil supplementation in pregnancy: a randomised controlled trial","volume":"1","author":"Dunstan","year":"2008","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"10.1016\/j.ntt.2016.02.002_bb0080","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1177\/019262339702500612","article-title":"Pathology of Minamata disease","volume":"6","author":"Eto","year":"1997","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0085","series-title":"Joint FAO\/WHO Expert Committee On Food Additives Sixty-first Meeting: Summary and Conclusions","author":"FAO\/WHO","year":"2003"},{"key":"10.1016\/j.ntt.2016.02.002_bb0090","doi-asserted-by":"crossref","unstructured":"Gao Y, Yan CH, Tian Y, Wang Y, Xie HF, Zhou X, Yu XD, Yu XG, Tong S, Zhou QX and others. Prenatal exposure to mercury and neurobehavioral development of neonates in Zhoushan City, China. Environ. Res. 2007; 3: 390\u20139.","DOI":"10.1016\/j.envres.2007.05.015"},{"key":"10.1016\/j.ntt.2016.02.002_bb0095","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0892-0362(97)00097-4","article-title":"Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury","volume":"6","author":"Grandjean","year":"1997","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408449509089885","article-title":"Minamata disease: methylmercury poisoning in Japan caused by environmental pollution","volume":"1","author":"Harada","year":"1995","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0105","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1542\/peds.111.1.e39","article-title":"Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4years of age","volume":"1","author":"Helland","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.ntt.2016.02.002_bb0110","first-page":"6","article-title":"Estimation of average concentration in the presence of nondetectable values","volume":"1","author":"Hornung","year":"1990","journal-title":"Appl. Occup. Environ. Hyg."},{"key":"10.1016\/j.ntt.2016.02.002_bb0115","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1016\/j.placenta.2005.01.005","article-title":"Essential fatty acid transfer and fetal development","author":"Innis","year":"2005","journal-title":"Placenta"},{"key":"10.1016\/j.ntt.2016.02.002_bb0120","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.jpeds.2007.07.008","article-title":"Beneficial effects of a polyunsaturated fatty acid on infant development: evidence from the inuit of arctic Quebec","volume":"3","author":"Jacobson","year":"2008","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ntt.2016.02.002_bb0125","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1289\/ehp.1408554","article-title":"Relation of prenatal methylmercury exposure from environmental sources to childhood IQ","volume":"8","author":"Jacobson","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2016.02.002_bb0130","doi-asserted-by":"crossref","unstructured":"Jedrychowski W, Jankowski J, Flak E, Skarupa A, Mroz E, Sochacka-Tatara E, Lisowska-Miszczyk I, Szpanowska-Wohn A, Rauh V, Skolicki Z and others. Effects of prenatal exposure to mercury on cognitive and psychomotor function in one-year-old infants: epidemiologic cohort study in Poland. Ann. Epidemiol. 2006; 6: 439\u201347.","DOI":"10.1016\/j.annepidem.2005.06.059"},{"issue":"Pt 2","key":"10.1016\/j.ntt.2016.02.002_bb0135","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1542\/peds.113.S2.641","article-title":"The Neonatal Intensive Care Unit Network Neurobehavioral Scale Procedures","volume":"3","author":"Lester","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.ntt.2016.02.002_bb0140","doi-asserted-by":"crossref","first-page":"e90","DOI":"10.1542\/peds.2009-0204","article-title":"Neonatal neurobehavior predicts medical and behavioral outcome","volume":"1","author":"Liu","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.ntt.2016.02.002_bb0145","doi-asserted-by":"crossref","unstructured":"Llop S, Guxens M, Murcia M, Lertxundi A, Ramon R, Riano I, Rebagliato M, Ibarluzea J, Tardon A, Sunyer J and others. Prenatal exposure to mercury and infant neurodevelopment in a multicenter cohort in Spain: study of potential modifiers. Am. J. Epidemiol. 2012; 5: 451\u201365.","DOI":"10.1093\/aje\/kwr328"},{"key":"10.1016\/j.ntt.2016.02.002_bb0150","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1289\/ehp.6587","article-title":"Blood organic mercury and dietary mercury intake: National Health and Nutrition Examination Survey, 1999 and 2000","volume":"5","author":"Mahaffey","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2016.02.002_bb0155","first-page":"653","article-title":"Main neurodevelopmental study of Seychellois children following in utero exposure to methylmercury from a maternal fish diet: outcome at six months","volume":"4","author":"Myers","year":"1995","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2016.02.002_bb0160","doi-asserted-by":"crossref","unstructured":"Myers GJ, Davidson PW, Cox C, Shamlaye CF, Palumbo D, Cernichiari E, Sloane-Reeves J, Wilding GE, Kost J, Huang LS and others. Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study. Lancet 2003; 9370: 1686\u201392.","DOI":"10.1016\/S0140-6736(03)13371-5"},{"key":"10.1016\/j.ntt.2016.02.002_bb0165","first-page":"346","article-title":"Decline in fish consumption among pregnant women after a national mercury advisory","volume":"2","author":"Oken","year":"2003","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0170","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1289\/ehp.8041","article-title":"Maternal fish consumption, hair mercury, and infant cognition in a U.S. cohort","volume":"10","author":"Oken","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2016.02.002_bb0175","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/aje\/kwn034","article-title":"Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3years in a US cohort","volume":"10","author":"Oken","year":"2008","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0180","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1021\/es801966w","article-title":"Levels in the U.S. population of those persistent organic pollutants (2003\u20132004) included in the Stockholm Convention or in other long range transboundary air pollution agreements","volume":"4","author":"Patterson","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0185","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jpeds.2009.09.042","article-title":"Neurobehavioral assessment predicts motor outcome in preterm infants","volume":"3","author":"Stephens","year":"2010","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ntt.2016.02.002_bb0190","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1289\/ehp.6187","article-title":"An assessment of the cord blood:maternal blood methylmercury ratio: implications for risk assessment","volume":"12","author":"Stern","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2016.02.002_bb0195","doi-asserted-by":"crossref","unstructured":"Stokes-Riner A, Thurston SW, Myers GJ, Duffy EM, Wallace J, Bonham M, Robson P, Shamlaye CF, Strain JJ, Watson G and others. A longitudinal analysis of prenatal exposure to methylmercury and fatty acids in the Seychelles. Neurotoxicol. Teratol. 2011; 2: 325\u20138.","DOI":"10.1016\/j.ntt.2010.11.003"},{"key":"10.1016\/j.ntt.2016.02.002_bb0200","doi-asserted-by":"crossref","unstructured":"Strain JJ, Davidson PW, Bonham MP, Duffy EM, Stokes-Riner A, Thurston SW, Wallace JM, Robson PJ, Shamlaye CF, Georger LA and others. Associations of maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in the Seychelles child Development Nutrition Study. Neurotoxicology 2008; 5: 776\u201382.","DOI":"10.1016\/j.neuro.2008.06.002"},{"key":"10.1016\/j.ntt.2016.02.002_bb0205","doi-asserted-by":"crossref","unstructured":"Strain JJ, Davidson PW, Thurston SW, Harrington D, Mulhern MS, McAfee AJ, van Wijngaarden E, Shamlaye CF, Henderson J, Watson GE and others. Maternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles. J. Nutr. 2012; 11: 1943\u20139.","DOI":"10.3945\/jn.112.163493"},{"key":"10.1016\/j.ntt.2016.02.002_bb0210","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-3016.2012.01288.x","article-title":"NICU Network Neurobehavioral Scale profiles predict developmental outcomes in a low-risk sample","volume":"4","author":"Sucharew","year":"2012","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0215","doi-asserted-by":"crossref","unstructured":"Suzuki K, Nakai K, Sugawara T, Nakamura T, Ohba T, Shimada M, Hosokawa T, Okamura K, Sakai T, Kurokawa N and others. Neurobehavioral effects of prenatal exposure to methylmercury and PCBs, and seafood intake: neonatal behavioral assessment scale results of Tohoku study of child development. Environ. Res. 2010; 7: 699\u2013704.","DOI":"10.1016\/j.envres.2010.07.001"},{"key":"10.1016\/j.ntt.2016.02.002_bb0220","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/jcap.12042","article-title":"Grandchild of the NBAS: the NICU Network Neurobehavioral Scale (NNNS): a review of the research using the NNNS","volume":"3","author":"Tronick","year":"2013","journal-title":"J. Child Adolesc. Psychiatr. Nurs."},{"key":"10.1016\/j.ntt.2016.02.002_bb0225","unstructured":"USDA. National Nutrient Database."},{"key":"10.1016\/j.ntt.2016.02.002_bb0230","series-title":"Fish Consumption Advisories","author":"USEPA","year":"2004"},{"key":"10.1016\/j.ntt.2016.02.002_bb0235","doi-asserted-by":"crossref","first-page":"360","DOI":"10.2188\/jea.JE20120168","article-title":"Associations of prenatal mercury exposure from maternal fish consumption and polyunsaturated fatty acids with child neurodevelopment: a prospective cohort study in Italy","volume":"5","author":"Valent","year":"2013","journal-title":"J. Epidemiol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0240","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ntt.2009.07.004","article-title":"Low-level prenatal exposure to nicotine and infant neurobehavior","volume":"6","author":"Yolton","year":"2009","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0245","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.ntt.2011.08.003","article-title":"Prenatal exposure to bisphenol A and phthalates and infant neurobehavior","volume":"5","author":"Yolton","year":"2011","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2016.02.002_bb0250","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/1476-069X-12-79","article-title":"Impact of low-level gestational exposure to organophosphate pesticides on neurobehavior in early infancy: a prospective study","volume":"1","author":"Yolton","year":"2013","journal-title":"Environ. Health"}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036216300071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036216300071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:21:52Z","timestamp":1760210512000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036216300071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":50,"alternative-id":["S0892036216300071"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2016.02.002","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-level gestational exposure to mercury and maternal fish consumption: Associations with neurobehavior in early infancy","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2016.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}