{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T22:26:57Z","timestamp":1780612017063,"version":"3.54.1"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NCTR Protocol","award":["E07601.01."],"award-info":[{"award-number":["E07601.01."]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.ntt.2020.106890","type":"journal-article","created":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T11:37:16Z","timestamp":1589283436000},"page":"106890","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat"],"prefix":"10.1016","volume":"80","author":[{"given":"Susan M.","family":"Burks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Bowyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Walters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Talpos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0005","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/ALN.0000000000000477","article-title":"Long-term effects of single or multiple neonatal sevoflurane exposures on rat hippocampal ultrastructure","volume":"122","author":"Amrock","year":"2015","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ntt.2020.106890_bb0010","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1196\/annals.1432.005","article-title":"Brain region-specific neurodegenerative profiles showing the relative importance of amphetamine dose, hyperthermia, seizures and the blood-brain barrier","volume":"1139","author":"Bowyer","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ntt.2020.106890_bb0015","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.neuro.2018.09.008","article-title":"The time course of blood brain barrier leakage and its implications on the progression of methamphetamine-induced seizures","volume":"69","author":"Bowyer","year":"2018","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2020.106890_bb0020","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.neuro.2018.02.005","article-title":"Microglial activation and vascular responses that are associated with early thalamic neurodegeneration resulting from thiamine deficiency","volume":"65","author":"Bowyer","year":"2018","journal-title":"Neurotoxicology"},{"issue":"4","key":"10.1016\/j.ntt.2020.106890_bb0025","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/ALN.0b013e3181d049cd","article-title":"Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain","volume":"112","author":"Brambrink","year":"2010","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0030","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/ALN.0b013e318242b2cd","article-title":"Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain","volume":"116","author":"Brambrink","year":"2012","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0035","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/ALN.0b013e318221fbbd","article-title":"Developmental stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex","volume":"115","author":"Briner","year":"2011","journal-title":"Anesthesiology"},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0040","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/s00540-017-2375-6","article-title":"A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics","volume":"31","author":"Brioni","year":"2017","journal-title":"J. Anesth."},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0045","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1365-2559.1990.tb00788.x","article-title":"Monoclonal antibody Ki-67: its use in histopathology","volume":"17","author":"Brown","year":"1990","journal-title":"Histopathology"},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0050","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1210\/en.2007-0883","article-title":"The anteroventral bed nucleus of the stria terminalis differentially regulates hypothalamic-pituitary-adrenocortical axis responses to acute and chronic stress","volume":"149","author":"Choi","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.ntt.2020.106890_bb0055","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3389\/neuro.05.020.2009","article-title":"Cross-species analyses of the cortical GABAergic and subplate neural populations","volume":"3","author":"Clancy","year":"2009","journal-title":"Front. Neuroanat."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0060","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1527-3458.2001.tb00190.x","article-title":"Sevoflurance: approaching the ideal inhalational anesthetic. A pharmacologic, pharmacoeconomic, and clinical review","volume":"7","author":"Delgado-Herrera","year":"2001","journal-title":"CNS Drug Rev"},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0065","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/bja\/aet469","article-title":"Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions","volume":"113","author":"Deng","year":"2014","journal-title":"Br. J. Anaesth."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2020.106890_bb0070","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0166-4328(02)00286-3","article-title":"Nucleus accumbens shell and core dopamine: differential role in behavior and addiction","volume":"137","author":"Di Chiara","year":"2002","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0075","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-3782(79)90022-7","article-title":"Comparative aspects of the brain growth spurt","volume":"3","author":"Dobbing","year":"1979","journal-title":"Early Hum. Dev."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0080","first-page":"719","article-title":"Developmental neurotoxicity of environmental agents in the neonate","volume":"18","author":"Eriksson","year":"1997","journal-title":"Neurotoxicology"},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0085","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s12264-012-1260-4","article-title":"Sevoflurane exposure in 7-day-old rats affects neurogenesis, neurodegeneration and neurocognitive function","volume":"28","author":"Fang","year":"2012","journal-title":"Neurosci. Bull."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0090","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.tins.2012.09.004","article-title":"Newborn cortical neurons: only for neonates?","volume":"36","author":"Feliciano","year":"2013","journal-title":"Trends Neurosci."},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0095","doi-asserted-by":"crossref","first-page":"e1053","DOI":"10.1542\/peds.2011-0351","article-title":"Cognitive and behavioral outcomes after early exposure to anesthesia and surgery","volume":"128","author":"Flick","year":"2011","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0100","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0959-4388(96)80076-6","article-title":"The amygdala and emotion","volume":"6","author":"Gallagher","year":"1996","journal-title":"Curr. Opin. Neurobiol."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0105","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1213\/ANE.0b013e31826d37c5","article-title":"Early developmental exposure to volatile anesthetics causes behavioral defects in Caenorhabditis elegans","volume":"116","author":"Gentry","year":"2013","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.ntt.2020.106890_bb0110","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev-neuro-061010-113641","article-title":"Modulation of striatal projection systems by dopamine","volume":"34","author":"Gerfen","year":"2011","journal-title":"Annu. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0115","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/hipo.1077","article-title":"Dissociating hippocampal subregions: double dissociation between dentate gyrus and CA1","volume":"11","author":"Gilbert","year":"2001","journal-title":"Hippocampus"},{"issue":"12","key":"10.1016\/j.ntt.2020.106890_bb0120","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1002\/jat.3183","article-title":"Zebrafish as a model for studying the developmental neurotoxicity of propofol","volume":"35","author":"Guo","year":"2015","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.ntt.2020.106890_bb0125","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bbr.2015.04.018","article-title":"Basal ganglia circuit loops, dopamine and motivation: a review and enquiry","volume":"290","author":"Ikemoto","year":"2015","journal-title":"Behav. Brain Res."},{"issue":"7","key":"10.1016\/j.ntt.2020.106890_bb0130","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.braindev.2009.02.006","article-title":"Triggers of apoptosis in the immature brain","volume":"31","author":"Ikonomidou","year":"2009","journal-title":"Brain and Development"},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0135","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.bja.2019.03.011","article-title":"Mayo Anesthesia Safety in Kids continued: two new studies and a potential redirection of the field","volume":"122","author":"Ing","year":"2019","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.ntt.2020.106890_bb0140","doi-asserted-by":"crossref","DOI":"10.1213\/ANE.0000000000004619","article-title":"Exposure to surgery and anesthesia in early childhood and subsequent use of attention deficit hyperactivity disorder medications","author":"Ing","year":"2020","journal-title":"Anesth. Analg."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0145","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1097\/ALN.0b013e3182084a70","article-title":"Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice","volume":"114","author":"Istaphanous","year":"2011","journal-title":"Anesthesiology"},{"issue":"7","key":"10.1016\/j.ntt.2020.106890_bb0150","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1038\/sj.bjp.0703479","article-title":"Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats","volume":"130","author":"Jevtovic-Todorovic","year":"2000","journal-title":"Br. J. Pharmacol."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2020.106890_bb0155","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S0006-8993(01)02079-0","article-title":"A comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide","volume":"895","author":"Jevtovic-Todorovic","year":"2001","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0160","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1097\/ALN.0000000000001358","article-title":"Long-term fate mapping to assess the impact of postnatal isoflurane exposure on hippocampal progenitor cell productivity","volume":"125","author":"Jiang","year":"2016","journal-title":"Anesthesiology"},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0165","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/jat.1751","article-title":"Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish","volume":"33","author":"Kanungo","year":"2013","journal-title":"J. Appl. Toxicol."},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0170","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1515\/REVNEURO.2004.15.5.333","article-title":"A behavioral assessment of hippocampal function based on a subregional analysis","volume":"15","author":"Kesner","year":"2004","journal-title":"Rev. Neurosci."},{"issue":"10","key":"10.1016\/j.ntt.2020.106890_bb0175","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1111\/j.1460-9568.2011.07878.x","article-title":"Electrical activity patterns and the functional maturation of the neocortex","volume":"34","author":"Kilb","year":"2011","journal-title":"Eur. J. Neurosci."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0180","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/bja\/aex219","article-title":"Alternative technique or mitigating strategy for sevoflurane-induced neurodegeneration: a randomized controlled dose-escalation study of dexmedetomidine in neonatal rats","volume":"119","author":"Lee","year":"2017","journal-title":"Br. J. Anaesth."},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0185","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1460-9592.2009.02962.x","article-title":"Inhalational anesthesia vs total intravenous anesthesia (TIVA) for pediatric anesthesia","volume":"19","author":"Lerman","year":"2009","journal-title":"Paediatr. Anaesth."},{"key":"10.1016\/j.ntt.2020.106890_bb0190","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev.ne.19.030196.001445","article-title":"Physiology of the neurotrophins","volume":"19","author":"Lewin","year":"1996","journal-title":"Annu. Rev. Neurosci."},{"issue":"17","key":"10.1016\/j.ntt.2020.106890_bb0195","doi-asserted-by":"crossref","first-page":"8117","DOI":"10.1073\/pnas.91.17.8117","article-title":"Apoptosis in substantia nigra following developmental striatal excitotoxic injury","volume":"91","author":"Macaya","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0200","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1097\/00000542-199909000-00019","article-title":"Direct cerebral vasodilatory effects of sevoflurane and isoflurane","volume":"91","author":"Matta","year":"1999","journal-title":"Anesthesiology"},{"issue":"5868","key":"10.1016\/j.ntt.2020.106890_bb0205","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/297681a0","article-title":"Place navigation impaired in rats with hippocampal lesions","volume":"297","author":"Morris","year":"1982","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0210","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1242\/dev.116.1.201","article-title":"NeuN, a neuronal specific nuclear protein in vertebrates","volume":"116","author":"Mullen","year":"1992","journal-title":"Development"},{"key":"10.1016\/j.ntt.2020.106890_bb0215","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ntt.2016.10.012","article-title":"The genetics of isoflurane-induced developmental neurotoxicity","volume":"60","author":"Na","year":"2017","journal-title":"Neurotoxicol. Teratol."},{"issue":"5","key":"10.1016\/j.ntt.2020.106890_bb0220","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1037\/bne0000267","article-title":"When is the rat retrosplenial cortex required for stimulus integration?","volume":"132","author":"Nelson","year":"2018","journal-title":"Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0225","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0006-8993(78)90930-7","article-title":"Hippocampal connections and spatial discrimination","volume":"139","author":"Olton","year":"1978","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2020.106890_bb0230","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijdevneu.2015.04.002","article-title":"Developmental stage-dependent impact of midazolam on calbindin, calretinin and parvalbumin expression in the immature rat medial prefrontal cortex during the brain growth spurt","volume":"45","author":"Osterop","year":"2015","journal-title":"Int. J. Dev. Neurosci."},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0235","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ntt.2011.01.001","article-title":"Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys","volume":"33","author":"Paule","year":"2011","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2020.106890_bb0240","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2014"},{"issue":"7","key":"10.1016\/j.ntt.2020.106890_bb0245","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/pan.12372","article-title":"Erythropoietin protects newborn rat against sevoflurane-induced neurotoxicity","volume":"24","author":"Pellegrini","year":"2014","journal-title":"Paediatr. Anaesth."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0250","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/bja\/aex222","article-title":"Dexmedetomidine-mediated neuroprotection against sevoflurane-induced neurotoxicity extends to several brain regions in neonatal rats","volume":"119","author":"Perez-Zoghbi","year":"2017","journal-title":"Br. J. Anaesth."},{"issue":"8","key":"10.1016\/j.ntt.2020.106890_bb0255","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1523\/JNEUROSCI.12-08-02888.1992","article-title":"Differential and transient expression of GABAA receptor alpha-subunit mRNAs in the developing rat CNS","volume":"12","author":"Poulter","year":"1992","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ntt.2020.106890_bb0260","series-title":"Atlas of the Neonatal Rat Brain","author":"Ramachandra","year":"2011"},{"issue":"Suppl. 3","key":"10.1016\/j.ntt.2020.106890_bb0265","first-page":"511","article-title":"Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models","volume":"108","author":"Rice","year":"2000","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0270","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1750-3639.2007.00116.x","article-title":"Clinical anesthesia causes permanent damage to the fetal guinea pig brain","volume":"18","author":"Rizzi","year":"2008","journal-title":"Brain Pathol."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0275","doi-asserted-by":"crossref","first-page":"260","DOI":"10.4097\/kja.d.18.00244","article-title":"Cerebrovascular reactivity to hypercapnia during sevoflurane or desflurane anesthesia in rats","volume":"72","author":"Sakata","year":"2019","journal-title":"Korean J Anesthesiol"},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0280","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1093\/toxsci\/kfh224","article-title":"Developmental neurotoxicity of ketamine: morphometric confirmation, exposure parameters, and multiple fluorescent labeling of apoptotic neurons","volume":"81","author":"Scallet","year":"2004","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0285","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.brainres.2004.11.054","article-title":"Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons","volume":"1035","author":"Schmued","year":"2005","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.ntt.2020.106890_bb0290","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0361-9230(84)90148-5","article-title":"The connections of the mouse olfactory bulb: a study using orthograde and retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase","volume":"12","author":"Shipley","year":"1984","journal-title":"Brain Res. Bull."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0295","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/toxsci\/kfm084","article-title":"Ketamine-induced neuronal cell death in the perinatal rhesus monkey","volume":"98","author":"Slikker","year":"2007","journal-title":"Toxicol. Sci."},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0300","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.mayocp.2011.11.008","article-title":"Attention-deficit\/hyperactivity disorder after early exposure to procedures requiring general anesthesia","volume":"87","author":"Sprung","year":"2012","journal-title":"Mayo Clin. Proc."},{"issue":"2","key":"10.1016\/j.ntt.2020.106890_bb0305","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1213\/ane.0b013e3181af8015","article-title":"Beyond anesthetic properties: the effects of isoflurane on brain cell death, neurogenesis, and long-term neurocognitive function","volume":"110","author":"Stratmann","year":"2010","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.ntt.2020.106890_bb0310","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.neuro.2018.11.005","article-title":"Early life exposure to extended general anesthesia with isoflurane and nitrous oxide reduces responsivity on a cognitive test battery in the nonhuman primate","volume":"70","author":"Talpos","year":"2019","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.ntt.2020.106890_bb0315","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.neubiorev.2019.04.016","article-title":"Retrosplenial cortex and its role in cue-specific learning and memory","volume":"107","author":"Todd","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.ntt.2020.106890_bb0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00441-011-1196-4","article-title":"Immunohistological markers for proliferative events, gliogenesis, and neurogenesis within the adult hippocampus","volume":"345","author":"von Bohlen und Halbach","year":"2011","journal-title":"Cell Tissue Res."},{"issue":"4","key":"10.1016\/j.ntt.2020.106890_bb0325","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/ALN.0000000000002863","article-title":"GAS, PANDA, and MASK: no evidence of clinical anesthetic neurotoxicity!","volume":"131","author":"Vutskits","year":"2019","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ntt.2020.106890_bb0335","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.ntt.2016.11.005","article-title":"Review of preclinical studies on pediatric general anesthesia-induced developmental neurotoxicity","volume":"60","author":"Walters","year":"2017","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2020.106890_bb0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.ntt.2020.106891","article-title":"Acetyl-L-carnitine does not prevent neurodegeneration in a rodent model of prolonged neonatal anesthesia","author":"Walters","year":"2020","journal-title":"Neurotoxicol. Teratol."},{"issue":"4","key":"10.1016\/j.ntt.2020.106890_bb0340","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1097\/01.anes.0000344728.34332.5d","article-title":"Early exposure to anesthesia and learning disabilities in a population-based birth cohort","volume":"110","author":"Wilder","year":"2009","journal-title":"Anesthesiology"},{"issue":"17","key":"10.1016\/j.ntt.2020.106890_bb0345","doi-asserted-by":"crossref","first-page":"7368","DOI":"10.1523\/JNEUROSCI.5746-12.2013","article-title":"Modeling transformations of neurodevelopmental sequences across mammalian species","volume":"33","author":"Workman","year":"2013","journal-title":"J. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2020.106890_bb0350","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0165-3806(85)90263-9","article-title":"The development of Ammon\u2019s horn and the fascia dentata in the cat: a [3H]thymidine analysis","volume":"350","author":"Wyss","year":"1985","journal-title":"Brain Res."},{"key":"10.1016\/j.ntt.2020.106890_bb0355","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ijdevneu.2016.01.008","article-title":"A lasting effect of postnatal sevoflurane anesthesia on the composition of NMDA receptor subunits in rat prefrontal cortex","volume":"54","author":"Zhang","year":"2016","journal-title":"Int. J. Dev. Neurosci."},{"issue":"9","key":"10.1016\/j.ntt.2020.106890_bb0360","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1111\/aas.12163","article-title":"Sevoflurane causes neuronal apoptosis and adaptability changes of neonatal rats","volume":"57","author":"Zheng","year":"2013","journal-title":"Acta Anaesthesiol. Scand."},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0365","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/ALN.0b013e3182834d5d","article-title":"Sevoflurane anesthesia in pregnant mice induces neurotoxicity in fetal and offspring mice","volume":"118","author":"Zheng","year":"2013","journal-title":"Anesthesiology"},{"issue":"3","key":"10.1016\/j.ntt.2020.106890_bb0370","first-page":"111","article-title":"Dose-dependent effects of sevoflurane exposure during early lifetime on apoptosis in hippocampus and neurocognitive outcomes in Sprague-Dawley rats","volume":"8","author":"Zhou","year":"2016","journal-title":"Int J Physiol Pathophysiol Pharmacol"},{"issue":"7","key":"10.1016\/j.ntt.2020.106890_bb0375","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.ijdevneu.2009.06.010","article-title":"Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain","volume":"27","author":"Zou","year":"2009","journal-title":"Int. J. Dev. Neurosci."},{"issue":"12","key":"10.1016\/j.ntt.2020.106890_bb0380","doi-asserted-by":"crossref","first-page":"5437","DOI":"10.1172\/JCI76669","article-title":"Sustained increase in alpha5GABAA receptor function impairs memory after anesthesia","volume":"124","author":"Zurek","year":"2014","journal-title":"J. Clin. Invest."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089203621930176X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089203621930176X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:26:23Z","timestamp":1760210783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089203621930176X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":76,"alternative-id":["S089203621930176X"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2020.106890","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2020.106890","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"106890"}}