{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:14:35Z","timestamp":1792602875071,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003970","name":"Isfahan University of Medical Sciences","doi-asserted-by":"publisher","award":["398341"],"award-info":[{"award-number":["398341"]}],"id":[{"id":"10.13039\/501100003970","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003970","name":"Isfahan University of Medical Sciences","doi-asserted-by":"publisher","award":["2019-04-28"],"award-info":[{"award-number":["2019-04-28"]}],"id":[{"id":"10.13039\/501100003970","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.ntt.2021.106957","type":"journal-article","created":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T12:07:10Z","timestamp":1612267630000},"page":"106957","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["AChR is partly responsible in mice depressive-like behavior after Phosalone exposure"],"prefix":"10.1016","volume":"84","author":[{"given":"Mehdi","family":"Aliomrani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Mesripour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Sayahpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ntt.2021.106957_bb0005","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.cca.2004.03.009","article-title":"Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion","volume":"137","author":"Abdollahi","year":"2004","journal-title":"Comp. Biochem. Physiol. C. Toxicol. Pharmacol."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0010","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1021\/jf60210a016","article-title":"Persistence and metabolism of phosalone in soil","volume":"25","author":"Ambrosi","year":"1977","journal-title":"J. Agric. Food Chem."},{"issue":"3\u20134","key":"10.1016\/j.ntt.2021.106957_bb0015","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0091-3057(01)00549-4","article-title":"Acute exposure to a low or mild dose of soman: biochemical, behavioral and histopathological effects","volume":"69","author":"Baille","year":"2001","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0020","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/toxsci\/kfm024","article-title":"Zinc attenuates malathion-induced depressant-like behavior and confers neuroprotection in the rat brain","volume":"97","author":"Brocardo","year":"2007","journal-title":"Toxicol. Sci."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0025","article-title":"Phosalone-induced changes in regional cholinesterase activities in rat brain during behavioral tolerance","volume":"3","author":"Chetan","year":"2009","journal-title":"African Res. Rev."},{"issue":"5","key":"10.1016\/j.ntt.2021.106957_bb0030","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1080\/02652039009373929","article-title":"Residues of insecticides, and fungicides in fruit produced in Ontario, Canada, 1986\u20131988","volume":"7","author":"Frank","year":"1990","journal-title":"Food Addit. Contam."},{"issue":"21","key":"10.1016\/j.ntt.2021.106957_bb0035","doi-asserted-by":"crossref","first-page":"4999","DOI":"10.3748\/wjg.v22.i21.4999","article-title":"Phosalone-induced inflammation and oxidative stress in the colon: evaluation and treatment","volume":"22","author":"Ghasemi-Niri","year":"2016","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0040","doi-asserted-by":"crossref","DOI":"10.1007\/s12011-018-1463-2","article-title":"Chronic oral arsenic exposure and its correlation with serum S100B concentration","volume":"189","author":"Golmohammadi","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.ntt.2021.106957_bb0045","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.envres.2016.08.020","article-title":"Anxiety and depression following cumulative low-level exposure to organophosphate pesticides","volume":"151","author":"Harrison","year":"2016","journal-title":"Environ. Res."},{"issue":"11","key":"10.1016\/j.ntt.2021.106957_bb0050","doi-asserted-by":"crossref","first-page":"A542","DOI":"10.1289\/ehp.109-a542a","article-title":"The Tokyo attacks in retrospect Sarin leads to memory loss","volume":"109","author":"Hood","year":"2001","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ntt.2021.106957_bb0055","article-title":"Rivastigmine restores 5-HT 1A receptor levels in the hippocampus of olfactory bulbectomized mice","volume":"2014","author":"Islam","year":"2014","journal-title":"Adv. Alzheimer's Dis."},{"key":"10.1016\/j.ntt.2021.106957_bb0060","series-title":"Active Compound Combinations and Methods to Protect the Propagation Material of Plants","author":"Jeschke","year":"2019"},{"key":"10.1016\/j.ntt.2021.106957_bb0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.cbi.2015.12.014","article-title":"Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system","volume":"245","author":"Judge","year":"2016","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.ntt.2021.106957_bb0070","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ecoenv.2018.05.055","article-title":"Comparative evaluation of toxicological effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based and cypermethrin-based pesticides","volume":"160","author":"Korkmaz","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0075","first-page":"174","article-title":"Inhibition of acetylcholinesterase and butyrylcholinesterase by phosalone via bioactivation","volume":"38","author":"Lim","year":"1995","journal-title":"Appl. Biol. Chem."},{"issue":"5","key":"10.1016\/j.ntt.2021.106957_bb0080","doi-asserted-by":"crossref","first-page":"628","DOI":"10.2174\/1385272823666190408114001","article-title":"Treatment of organophosphate poisoning with experimental oximes: a review","volume":"23","author":"Lorke","year":"2019","journal-title":"Curr. Org. Chem."},{"issue":"6\u20137","key":"10.1016\/j.ntt.2021.106957_bb0085","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00008877-199711000-00010","article-title":"The forced swimming test as a model for core and component behavioral effects of antidepressant drugs","volume":"8","author":"Lucki","year":"1997","journal-title":"Behav. Pharmacol."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0090","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neuro.2009.10.012","article-title":"An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint","volume":"31","author":"Mamczarz","year":"2010","journal-title":"Neurotoxicology"},{"issue":"5","key":"10.1016\/j.ntt.2021.106957_bb0095","first-page":"809","article-title":"Neurotoxic effects associated with current uses of organophosphorus compounds","volume":"27","author":"Mangas","year":"2016","journal-title":"J. Braz. Chem. Soc."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0100","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4103\/2322-1232.222613","article-title":"Effect of scopolamine and mecamylamine on antidepressant effect of rivastigmine in a behavioral despair test in mice","volume":"6","author":"Mesripour","year":"2017","journal-title":"J. Rep. Pharm. Sci."},{"issue":"9","key":"10.1016\/j.ntt.2021.106957_bb0105","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1073\/pnas.1219731110","article-title":"Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety-and depression-like behavior","volume":"110","author":"Mineur","year":"2013","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"6","key":"10.1016\/j.ntt.2021.106957_bb0110","first-page":"619","article-title":"Subacute poisoning with phosalone, an organophosphate insecticide","volume":"153","author":"O'Malley","year":"1990","journal-title":"West J. Med."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0115","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s12011-018-1553-1","article-title":"Is there any relevance between serum heavy metal concentration and BBB leakage in multiple sclerosis patients?","volume":"190","author":"Paknejad","year":"2019","journal-title":"Biol. Trace Elem. Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0120","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0041-008X(76)80010-5","article-title":"Acute oral and percutaneous toxicity of phosalone in the rat, in comparison with azinphosmethyl and parathion","volume":"37","author":"Pasquet","year":"1976","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"4","key":"10.1016\/j.ntt.2021.106957_bb0125","first-page":"273","article-title":"Organophosphate pesticide poisoning","volume":"129","author":"Peoples","year":"1978","journal-title":"West J. Med."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0130","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1124\/jpet.114.214932","article-title":"Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds","volume":"350","author":"Pereira","year":"2014","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"10","key":"10.1016\/j.ntt.2021.106957_bb0135","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.3109\/13880209.2014.889176","article-title":"Silymarin alleviates bleomycin-induced pulmonary toxicity and lipid peroxidation in mice","volume":"52","author":"Razavi-Azarkhiavi","year":"2014","journal-title":"Pharm. Biol."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0140","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0165-1781(81)90012-3","article-title":"Physostigmine induction of depressive symptomatology in normal human subjects","volume":"4","author":"Risch","year":"1981","journal-title":"Psychiatry Res."},{"issue":"2","key":"10.1016\/j.ntt.2021.106957_bb0145","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.ntt.2004.12.002","article-title":"Neuropsychological effects of long-term exposure to organophosphate pesticides","volume":"27","author":"Rold\u00e1n-Tapia","year":"2005","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.ntt.2021.106957_bb0150","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.cortex.2015.10.003","article-title":"Organophosphate pesticide exposure and neurodegeneration","volume":"74","author":"S\u00e1nchez-Santed","year":"2016","journal-title":"Cortex"},{"issue":"4","key":"10.1016\/j.ntt.2021.106957_bb0155","first-page":"245","article-title":"Neurobehavioral toxicity with low doses of sarin and soman","volume":"12","author":"Sirkka","year":"1990","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"key":"10.1016\/j.ntt.2021.106957_bb0160","series-title":"The Pesticides Toxic Impact on the Human Health Condition and the Ecosystem","author":"Terziev","year":"2019"},{"issue":"6","key":"10.1016\/j.ntt.2021.106957_bb0165","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0045-6535(97)00167-7","article-title":"Variation in the sensitivity of aquatic species in relation to the classification of environmental pollutants","volume":"35","author":"Vaal","year":"1997","journal-title":"Chemosphere."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0170","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1179\/oeh.2002.8.1.27","article-title":"Long-term neurobehavioral effects of mild poisonings with organophosphate and n-methyl carbamate pesticides among banana workers","volume":"8","author":"Wesseling","year":"2002","journal-title":"Int. J. Occup. Environ. Health"},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0175","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/ana.21024","article-title":"Human brain structural change related to acute single exposure to sarin","volume":"61","author":"Yamasue","year":"2007","journal-title":"Ann. Neurol."},{"issue":"1","key":"10.1016\/j.ntt.2021.106957_bb0180","first-page":"1","article-title":"Biochar and clinoptilolite zeolite on selected chemical properties of soil cultivated with maize (Zea mays L.)","volume":"8","author":"Zaidun","year":"2019","journal-title":"Eur. J. Soil Sci."},{"key":"10.1016\/j.ntt.2021.106957_bb0185","doi-asserted-by":"crossref","first-page":"745","DOI":"10.2471\/BLT.08.054122","article-title":"Pesticide exposure and suicidal ideation in rural communities in Zhejiang province, China","volume":"87","author":"Zhang","year":"2009","journal-title":"Bull. World Health Organ."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036221000118?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0892036221000118?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:40:46Z","timestamp":1777578046000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0892036221000118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":37,"alternative-id":["S0892036221000118"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2021.106957","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AChR is partly responsible in mice depressive-like behavior after Phosalone exposure","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2021.106957","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106957"}}