{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:12:11Z","timestamp":1789708331430,"version":"4.0.1"},"reference-count":116,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination of Higher Education Personnel Improvement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Foundation for Research Support of Rio Grande do Sul State","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurotoxicology and Teratology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.ntt.2021.107034","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T16:12:28Z","timestamp":1632931948000},"page":"107034","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Long-lasting behavioral effects of quinpirole exposure on zebrafish"],"prefix":"10.1016","volume":"88","author":[{"given":"Debora Dreher","family":"Nabinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefani","family":"Altenhofen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Vasconcellos","family":"Peixoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Maria Kuhl","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla Denise","family":"Bonan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0005","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s12640-020-00196-y","article-title":"The effect of orexin receptor antagonism on Quinpirole-induced compulsive-like checking behavior in rats","volume":"38","author":"Abounoori","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.ntt.2021.107034_bb0010","first-page":"1","article-title":"Neuroteratology and animal modeling of brain disorders","volume":"29","author":"Archer","year":"2016","journal-title":"Curr. Top. Behav. Neurosci."},{"issue":"3\u20134","key":"10.1016\/j.ntt.2021.107034_bb0015","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s12640-010-9163-5","article-title":"Epigenetics and biomarkers in the staging of neuropsychiatric disorders","volume":"18","author":"Archer","year":"2010","journal-title":"Neurotox. Res."},{"issue":"6","key":"10.1016\/j.ntt.2021.107034_bb0020","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1001\/jama.2019.22360","article-title":"Diagnosis and treatment of Parkinson disease: a review","volume":"323","author":"Armstrong","year":"2020","journal-title":"JAMA."},{"issue":"1\u20133","key":"10.1016\/j.ntt.2021.107034_bb0025","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejphar.2009.03.048","article-title":"High fat diet and food restriction differentially modify the behavioral effects of quinpirole and raclopride in rats","volume":"610","author":"Baladi","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ntt.2021.107034_bb0030","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3389\/fncel.2014.00058","article-title":"Genetic aspects of autism spectrum disorders: insights from animal models","volume":"8","author":"Banerjee","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0035","doi-asserted-by":"crossref","first-page":"172841","DOI":"10.1016\/j.pbb.2019.172841","article-title":"Aripiprazole prevents stress-induced anxiety and social impairment, but impairs antipredatory behavior in zebrafish","volume":"189","author":"Barcellos","year":"2020","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0040","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1124\/pr.110.002642","article-title":"The physiology, signaling, and pharmacology of dopamine receptors","volume":"63","author":"Beaulieu","year":"2011","journal-title":"Pharmacol. Rev."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0045","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.tins.2007.03.006","article-title":"Dopamine neuron systems in the brain: an update","volume":"30","author":"Bj\u00f6rklund","year":"2007","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0050","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1476-069X-7-50","article-title":"Potential developmental neurotoxicity of pesticides used in Europe","volume":"7","author":"Bj\u00f8rling-Poulsen","year":"2008","journal-title":"Environ. Health"},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0055","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.nlm.2009.07.001","article-title":"A one-trial inhibitory avoidance task to zebrafish: rapid acquisition of an NMDA-dependent long-term memory","volume":"92","author":"Blank","year":"2009","journal-title":"Neurobiol. Learn. Mem."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb0060","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/dvdy.20075","article-title":"Evolution and expression of D2 and D3 dopamine receptor genes in zebrafish","volume":"230","author":"Boehmler","year":"2004","journal-title":"Dev. Dyn."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0065","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1601-183X.2006.00243.x","article-title":"D4 dopamine receptor genes of zebrafish and effects of the antipsychotic clozapine on larval swimming behaviour","volume":"6","author":"Boehmler","year":"2007","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.ntt.2021.107034_bb0070","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jneumeth.2017.02.007","article-title":"Modeling tics in rodents: conceptual challenges and paths forward","volume":"292","author":"Bortolato","year":"2017","journal-title":"J. Neurosci. Methods"},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0075","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/BF00427425","article-title":"Passive avoidance in rats: disruption by dopamine applied to the nucleus accumbens","volume":"83","author":"Bracs","year":"1984","journal-title":"Psychopharmacology"},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0080","doi-asserted-by":"crossref","first-page":"591","DOI":"10.3390\/nu10050591","article-title":"Dietary neurotransmitters: a narrative review on current knowledge","volume":"10","author":"Briguglio","year":"2018","journal-title":"Nutrients"},{"issue":"1\u20132","key":"10.1016\/j.ntt.2021.107034_bb0085","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0166-4328(00)00225-4","article-title":"D-amphetamine facilitation of Morris water task performance is blocked by eticlopride and correlated with increased dopamine synthesis in the prefrontal cortex","volume":"114","author":"Brown","year":"2000","journal-title":"Behav. Brain Res."},{"issue":"2\u20133","key":"10.1016\/j.ntt.2021.107034_bb0090","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000338830","article-title":"Schizophrenia and substance abuse comorbidity: nicotine addiction and the neonatal quinpirole model","volume":"34","author":"Brown","year":"2012","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0095","doi-asserted-by":"crossref","first-page":"626","DOI":"10.3389\/fpsyt.2019.00626","article-title":"Molecular imaging of opioid and dopamine systems: insights into the pharmacogenetics of opioid use disorders","volume":"10","author":"Burns","year":"2019","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.ntt.2021.107034_bb0100","doi-asserted-by":"crossref","first-page":"135540","DOI":"10.1016\/j.neulet.2020.135540","article-title":"The neurodevelopmental role of dopaminergic signaling in neurological disorders","volume":"741","author":"Cai","year":"2021","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0105","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1017\/S1092852913000564","article-title":"Animal models of obsessive-compulsive spectrum disorders","volume":"19","author":"Camilla d\u2019Angelo","year":"2014","journal-title":"CNS Spectr."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0110","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s11920-019-1018-z","article-title":"Advances in the treatment of Tourette\u2019s disorder","volume":"21","author":"Chadehumbe","year":"2019","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.ntt.2021.107034_bb0115","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.phrs.2018.01.016","article-title":"The role of dopaminergic midbrain in Alzheimer\u2019s disease: translating basic science into clinical practice","volume":"130","author":"D\u2019Amelio","year":"2018","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.ntt.2021.107034_bb0120","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.bbr.2015.07.017","article-title":"Ketamine induces anxiolytic effects in adult zebrafish: a multivariate statistics approach","volume":"292","author":"De Campos","year":"2015","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0125","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.coph.2008.12.002","article-title":"Getting specialized: presynaptic and postsynaptic dopamine D2 receptors","volume":"9","author":"De Mei","year":"2009","journal-title":"Curr. Opin. Pharmacol."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb0130","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF02246662","article-title":"Behavioural effects in the rat of the putative dopamine D3 receptor agonist 7-OH-DPAT: comparison with quinpirole and apomorphine","volume":"124","author":"Depoortere","year":"1996","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0135","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0006-8993(89)90243-6","article-title":"D2-agonist quinpirole induces perseveration of routes and hyperactivity but no perseveration of movements","volume":"490","author":"Eilam","year":"1989","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0140","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0166-4328(05)80077-4","article-title":"Differential effects of D1 and D2 dopamine agonists on stereotyped locomotion in rats","volume":"45","author":"Eilam","year":"1991","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0145","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0166-4328(93)90046-S","article-title":"Longlasting consequences of chronic treatment with the dopamine agonist quinpirole for the undrugged behavior of rats","volume":"54","author":"Einat","year":"1993","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0150","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1021\/acschemneuro.6b00014","article-title":"Behavioral analysis of dopaminergic activation in Zebrafish and rats reveals similar phenotypes","volume":"7","author":"Ek","year":"2016","journal-title":"ACS Chem. Neurosci."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0155","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1515\/REVNEURO.2007.18.1.37","article-title":"Insights into the role of dopamine receptor systems in learning and memory","volume":"18","author":"El-Ghundi","year":"2007","journal-title":"Rev. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0160","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ejphar.2016.03.060","article-title":"The influence of dopaminergic system in medial prefrontal cortex on ketamine-induced amnesia in passive avoidance task in mice","volume":"781","author":"Farahmandfar","year":"2016","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0165","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00213-016-4491-7","article-title":"Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine","volume":"234","author":"F\u00e9lix","year":"2017","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2021.107034_bb0170","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.taap.2017.02.013","article-title":"Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure","volume":"321","author":"F\u00e9lix","year":"2017","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ntt.2021.107034_bb0175","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/7854_2011_180","article-title":"Using zebrafish to unravel the genetics of complex brain disorders","volume":"12","author":"Gerlai","year":"2012","journal-title":"Curr. Top. Behav. Neurosci."},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0180","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0091-3057(00)00422-6","article-title":"Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects","volume":"67","author":"Gerlai","year":"2000","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2021.107034_bb0185","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S1054-3589(08)60846-7","article-title":"The cortical dopamine system: role in memory and cognition","volume":"42","author":"Goldman-Rakic","year":"1998","journal-title":"Adv. Pharmacol."},{"issue":"7","key":"10.1016\/j.ntt.2021.107034_bb0190","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1517\/17460441.2011.577772","article-title":"Animal models of obsessive-compulsive disorder: recent findings and future directions","volume":"6","author":"Hoffman","year":"2011","journal-title":"Expert Opin. Drug Discovery"},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0195","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1177\/0269881114563634","article-title":"Glutamate and dopamine in schizophrenia: an update for the 21st century","volume":"29","author":"Howes","year":"2015","journal-title":"J. Psychopharmacol."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb0200","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0014-2999(88)90540-7","article-title":"Effects of haloperidol, sulpiride and SCH 23390 on passive avoidance learning in mice","volume":"151","author":"Ichihara","year":"1988","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0205","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.pbb.2012.12.010","article-title":"Acute administration of dopaminergic drugs has differential effects on locomotion in larval zebrafish","volume":"103","author":"Irons","year":"2013","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2021.107034_bb0210","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.2994","article-title":"Modafinil decreases anxiety-like behaviour in zebrafish","volume":"5","author":"Johnson","year":"2017","journal-title":"PeerJ."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0215","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.bcp.2008.05.010","article-title":"The effects of environmental neurotoxicants on the dopaminergic system: a possible role in drug addiction","volume":"76","author":"Jones","year":"2008","journal-title":"Biochem. Pharmacol."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0220","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2486\/indhealth.47.459","article-title":"Neurodevelopmental toxicity risks due to occupational exposure to industrial chemicals during pregnancy","volume":"47","author":"Julvez","year":"2009","journal-title":"Ind. Health"},{"key":"10.1016\/j.ntt.2021.107034_bb0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pbb.2017.01.005","article-title":"Dopaminergic control of anxiety in young and aged zebrafish","volume":"157","author":"Kacprzak","year":"2017","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0230","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1089\/zeb.2012.0861","article-title":"Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond","volume":"10","author":"Kalueff","year":"2013","journal-title":"Zebrafish."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0235","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.tips.2013.12.002","article-title":"Zebrafish as an emerging model for studying complex brain disorders","volume":"35","author":"Kalueff","year":"2014","journal-title":"Trends Pharmacol. Sci."},{"issue":"13","key":"10.1016\/j.ntt.2021.107034_bb0240","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1111\/bph.13754","article-title":"Zebrafish models in neuropsychopharmacology and CNS drug discovery","volume":"174","author":"Khan","year":"2017","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0245","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10571-018-0632-3","article-title":"Dopamine: functions, signaling, and association with neurological diseases","volume":"39","author":"Klein","year":"2019","journal-title":"Cell. Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0149-7634(94)00019-W","article-title":"Dopamine receptor supersensitivity","volume":"19","author":"Kostrzewa","year":"1995","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0255","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0091-3057(91)90219-R","article-title":"Ontogenic homologous supersensitization of quinpirole-induced yawning in rats","volume":"39","author":"Kostrzewa","year":"1991","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ntt.2021.107034_bb0260","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/7854_2015_395","article-title":"Lifelong rodent model of tardive dyskinesia-persistence after antipsychotic drug withdrawal","volume":"29","author":"Kostrzewa","year":"2016","journal-title":"Curr. Top. Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0265","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0091-3057(93)90496-G","article-title":"Low-dose quinpirole ontogenically sensitizes to quinpirole-induced yawning in rats","volume":"44","author":"Kostrzewa","year":"1993","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0270","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s12640-010-9192-0","article-title":"Stereotypic progressions in psychotic behavior","volume":"19","author":"Kostrzewa","year":"2011","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.ntt.2021.107034_bb0275","series-title":"Handbook of Neurotoxicity","first-page":"2315","article-title":"Tardive dyskinesia: Outcome of antipsychotic treatment and brain damage?, in section on diseases and disorders relevant to neurotoxins","author":"Kostrzewa","year":"2014"},{"key":"10.1016\/j.ntt.2021.107034_bb0280","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/7854_2015_397","article-title":"Perinatal 6-Hydroxydopamine modeling of ADHD","volume":"29","author":"Kostrzewa","year":"2016","journal-title":"Curr. Top. Behav. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0285","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/7854_2015_396","article-title":"Perinatal 6-Hydroxydopamine to produce a lifelong model of severe Parkinson\u2019s disease","volume":"29","author":"Kostrzewa","year":"2016","journal-title":"Curr. Top. Behav. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2021.107034_bb0290","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11064-015-1757-0","article-title":"Perinatal treatments with the dopamine D\u2082-receptor agonist quinpirole produces permanent D\u2082-receptor supersensitization: a model of schizophrenia","volume":"41","author":"Kostrzewa","year":"2016","journal-title":"Neurochem. Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0295","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.bbr.2004.04.015","article-title":"Effects of quinpirole on operant conditioning: perseveration of behavioral components","volume":"155","author":"Kurylo","year":"2004","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0300","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0031-9384(03)00218-X","article-title":"Effects of quinpirole on behavioral extinction","volume":"80","author":"Kurylo","year":"2003","journal-title":"Physiol. Behav."},{"issue":"39","key":"10.1016\/j.ntt.2021.107034_bb0305","doi-asserted-by":"crossref","first-page":"13488","DOI":"10.1523\/JNEUROSCI.1638-12.2012","article-title":"The conserved dopaminergic diencephalospinal tract mediates vertebrate locomotor development in zebrafish larvae","volume":"32","author":"Lambert","year":"2012","journal-title":"J. Neurosci."},{"issue":"Pt A","key":"10.1016\/j.ntt.2021.107034_bb0310","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.pnpbp.2018.02.010","article-title":"Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity","volume":"84","author":"Lange","year":"2018","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ntt.2021.107034_bb0315","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.bbr.2017.01.005","article-title":"Role of D2 dopamine receptors of the ventral pallidum in inhibitory avoidance learning","volume":"321","author":"L\u00e9n\u00e1rd","year":"2017","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0320","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1002\/dvdy.21130","article-title":"Cloning and spatial and temporal expression of the zebrafish dopamine D1 receptor","volume":"236","author":"Li","year":"2007","journal-title":"Dev. Dyn."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb9115","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/FBP.0b013e32833a5c68","article-title":"Yawning and locomotor behavior induced by dopamine receptor agonists in mice and rats","volume":"21","author":"Li","year":"2010","journal-title":"Behavioural Pharmacology"},{"key":"10.1016\/j.ntt.2021.107034_bb0325","doi-asserted-by":"crossref","first-page":"126635","DOI":"10.1016\/j.chemosphere.2020.126635","article-title":"Carbofuran induces increased anxiety-like behaviors in female zebrafish (Danio rerio) through disturbing dopaminergic\/norepinephrinergic system","volume":"253","author":"Liu","year":"2020","journal-title":"Chemosphere."},{"key":"10.1016\/j.ntt.2021.107034_bb0330","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.pbb.2015.08.011","article-title":"Neonatal quinpirole treatment produces prepulse inhibition deficits in adult male and female rats","volume":"137","author":"Maple","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0335","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1124\/jpet.116.238634","article-title":"Effects of repeated ropinirole treatment on phencyclidine-induced hyperlocomotion, prepulse inhibition deficits, and social avoidance in rats","volume":"361","author":"Maple","year":"2017","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ntt.2021.107034_bb0340","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.3389\/fphar.2020.01003","article-title":"Dopamine receptor subtypes, physiology and pharmacology: new ligands and concepts in schizophrenia","volume":"11","author":"Martel","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb0345","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/BF02251287","article-title":"Effects of daily SKF 38393, quinpirole, and SCH 23390 treatments on locomotor activity and subsequent sensitivity to apomorphine","volume":"110","author":"Mattingly","year":"1993","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ntt.2021.107034_bb0350","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neuroscience.2013.03.036","article-title":"Low dopamine D5 receptor density in hippocampus in an animal model of attention-deficit\/hyperactivity disorder (ADHD)","volume":"242","author":"Medin","year":"2013","journal-title":"Neuroscience."},{"issue":"11","key":"10.1016\/j.ntt.2021.107034_bb0355","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078258","article-title":"Initial d2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats","volume":"8","author":"Merritt","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ntt.2021.107034_bb0360","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.neulet.2018.08.009","article-title":"Ketamine modulates aggressive behavior in adult zebrafish","volume":"684","author":"Michelotti","year":"2018","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ntt.2021.107034_bb0365","doi-asserted-by":"crossref","DOI":"10.1177\/1179069518779829","article-title":"Physiological and functional basis of dopamine receptors and their role in neurogenesis: possible implication for Parkinson\u2019s disease","volume":"12","author":"Mishra","year":"2018","journal-title":"J. Exp. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0370","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.euroneuro.2019.12.120","article-title":"Role of the serotonergic system in ethanol-induced aggression and anxiety: a pharmacological approach using the zebrafish model","volume":"32","author":"M\u00fcller","year":"2020","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.ntt.2021.107034_bb0375","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/j.scitotenv.2017.10.057","article-title":"Nickel exposure alters behavioral parameters in larval and adult zebrafish","volume":"624","author":"Nabinger","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.ntt.2021.107034_bb0380","doi-asserted-by":"crossref","first-page":"110179","DOI":"10.1016\/j.pnpbp.2020.110179","article-title":"Feeding status alters exploratory and anxiety-like behaviors in zebrafish larvae exposed to quinpirole","volume":"108","author":"Nabinger","year":"2021","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0385","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1037\/0735-7044.113.1.152","article-title":"The dopaminergic modulation of fear: quinpirole impairs the recall of emotional memories in rats","volume":"113","author":"Nader","year":"1999","journal-title":"Behav. Neurosci."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0390","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1037\/0735-7044.113.5.891","article-title":"Inhibition of the mesoamygdala dopaminergic pathway impairs the retrieval of conditioned fear associations","volume":"113","author":"Nader","year":"1999","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ntt.2021.107034_bb0395","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.bbr.2016.01.034","article-title":"Modulatory effects of dopamine receptors on associative learning performance in zebrafish (Danio rerio)","volume":"303","author":"Naderi","year":"2016","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ntt.2021.107034_bb0400","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pnpbp.2016.01.002","article-title":"Dopamine receptors participate in acquisition and consolidation of latent learning of spatial information in zebrafish (Danio rerio)","volume":"67","author":"Naderi","year":"2016","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"7","key":"10.1016\/j.ntt.2021.107034_bb0405","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1358\/mf.1999.21.7.550110","article-title":"Behavioral profile of quinpirole in agonistic encounters between male mice","volume":"21","author":"Navarro","year":"1999","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"issue":"11","key":"10.1016\/j.ntt.2021.107034_bb0410","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/s41398-017-0011-8","article-title":"A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission","volume":"7","author":"Nielsen","year":"2017","journal-title":"Transl. Psychiatry"},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0415","first-page":"319","article-title":"Amphetamine-induced enhancement of neostriatal in vivo microdialysate dopamine content in rats, quinpirole-primed as neonates","volume":"53","author":"Nowak","year":"2001","journal-title":"Pol. J. Pharmacol."},{"key":"10.1016\/j.ntt.2021.107034_bb0420","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3389\/fnagi.2019.00175","article-title":"Dopamine and dopamine receptors in Alzheimer\u2019s disease: a systematic review and network meta-analysis","volume":"11","author":"Pan","year":"2019","journal-title":"Front. Aging Neurosci."},{"issue":"Pt B","key":"10.1016\/j.ntt.2021.107034_bb0425","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.pbb.2015.08.014","article-title":"Behavioral, endocrine, and neuronal alterations in zebrafish (Danio rerio) following sub-chronic coadministration of fluoxetine and ketamine","volume":"139","author":"Pittman","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"4","key":"10.1016\/j.ntt.2021.107034_bb0430","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1101\/lm.96605","article-title":"Systemic blockade of D2-like dopamine receptors facilitates extinction of conditioned fear in mice","volume":"12","author":"Ponnusamy","year":"2005","journal-title":"Learn. Mem."},{"key":"10.1016\/j.ntt.2021.107034_bb0435","first-page":"93","article-title":"Dopamine modulation of learning and memory in the prefrontal cortex: insights from studies in primates, rodents, and birds","volume":"8","author":"Puig","year":"2014","journal-title":"Front. Neural Circ."},{"key":"10.1016\/j.ntt.2021.107034_bb0440","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.physbeh.2016.12.032","article-title":"Gender differences in aggression and cortisol levels in zebrafish subjected to unpredictable chronic stress","volume":"171","author":"Rambo","year":"2017","journal-title":"Physiol. Behav."},{"issue":"Suppl. 3","key":"10.1016\/j.ntt.2021.107034_bb0445","first-page":"511","article-title":"Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models","volume":"108","author":"Rice","year":"2000","journal-title":"Environ. Health Perspect."},{"issue":"6","key":"10.1016\/j.ntt.2021.107034_bb0450","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.ntt.2011.05.011","article-title":"Behavioral and physiological effects of acute ketamine exposure in adult zebrafish","volume":"33","author":"Riehl","year":"2011","journal-title":"Neurotoxicol. Teratol."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2021.107034_bb0455","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/S0006-8993(00)03174-7","article-title":"The teleostean (zebrafish) dopaminergic system ascending to the subpallium (striatum) is located in the basal diencephalon (posterior tuberculum)","volume":"889","author":"Rink","year":"2001","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0460","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0165-3806(02)00354-1","article-title":"Development of the catecholaminergic system in the early zebrafish brain: an immunohistochemical study","volume":"137","author":"Rink","year":"2002","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.ntt.2021.107034_bb0465","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3389\/fnins.2017.00295","article-title":"Dopamine and the brainstem locomotor networks: from lamprey to human","volume":"11","author":"Ryczko","year":"2017","journal-title":"Front. Neurosci."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0470","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s002130050500","article-title":"Effects of dopamine agonists and antagonists on PCP-induced stereotyped behaviour and social isolation in the rat social interaction test","volume":"135","author":"Sams-Dodd","year":"1998","journal-title":"Psychopharmacology"},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0475","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1007\/s00726-012-1284-0","article-title":"Dopamine receptor antagonism disrupts social preference in zebrafish: a strain comparison study","volume":"43","author":"Scerbina","year":"2012","journal-title":"Amino Acids"},{"issue":"1\u20133","key":"10.1016\/j.ntt.2021.107034_bb0480","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ejphar.2008.07.002","article-title":"Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats","volume":"592","author":"Sevak","year":"2008","journal-title":"Eur. J. Pharmacol."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2021.107034_bb0485","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pbiomolbio.2015.04.008","article-title":"Epigenetic mechanisms in schizophrenia","volume":"118","author":"Shorter","year":"2015","journal-title":"Prog. Biophys. Mol. Biol."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0490","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1515\/rns.2011.012","article-title":"The role of dopaminergic signalling during larval zebrafish brain development: a tool for investigating the developmental basis of neuropsychiatric disorders","volume":"22","author":"Souza","year":"2011","journal-title":"Rev. Neurosci."},{"issue":"14","key":"10.1016\/j.ntt.2021.107034_bb0495","doi-asserted-by":"crossref","first-page":"5512","DOI":"10.1523\/JNEUROSCI.5548-10.2011","article-title":"Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae","volume":"31","author":"Souza","year":"2011","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.ntt.2021.107034_bb0500","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.tins.2014.02.011","article-title":"Zebrafish models for translational neuroscience research: from tank to bedside","volume":"37","author":"Stewart","year":"2014","journal-title":"Trends Neurosci."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0505","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/mp.2014.128","article-title":"Molecular psychiatry of zebrafish","volume":"20","author":"Stewart","year":"2015","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ntt.2021.107034_bb0510","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3389\/fnbeh.2016.00209","article-title":"Validity of quinpirole sensitization rat model of OCD: linking evidence from animal and clinical studies","volume":"10","author":"Stuchlik","year":"2016","journal-title":"Front. Behav. Neurosci."},{"issue":"1\u20132","key":"10.1016\/j.ntt.2021.107034_bb0515","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF02244757","article-title":"Dynamics of behavioral sensitization induced by the dopamine agonist quinpirole and a proposed central energy control mechanism [published correction appears in Psychopharmacology (Berl) 1994 Sep;116(1):124]","volume":"115","author":"Szechtman","year":"1994","journal-title":"Psychopharmacology"},{"issue":"Pt B","key":"10.1016\/j.ntt.2021.107034_bb0520","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.neubiorev.2016.04.019","article-title":"Obsessive-compulsive disorder: Insights from animal models","volume":"76","author":"Szechtman","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ntt.2021.107034_bb0525","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ncomms1171","article-title":"Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems","volume":"2","author":"Tay","year":"2011","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ntt.2021.107034_bb0530","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bbr.2013.07.012","article-title":"Social modulation of brain monoamine levels in zebrafish","volume":"253","author":"Teles","year":"2013","journal-title":"Behav. Brain Res."},{"issue":"3","key":"10.1016\/j.ntt.2021.107034_bb0535","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1152\/jn.90568.2008","article-title":"Endogenous dopamine suppresses initiation of swimming in prefeeding zebrafish larvae","volume":"100","author":"Thirumalai","year":"2008","journal-title":"J. Neurophysiol."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0540","first-page":"106","article-title":"Focus on: neurotransmitter systems","volume":"34","author":"Valenzuela","year":"2011","journal-title":"Alcohol Res. Health"},{"key":"10.1016\/j.ntt.2021.107034_bb0545","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3389\/fneur.2018.00347","article-title":"Zebrafish as an animal model for drug discovery in Parkinson\u2019s disease and other movement disorders: a systematic review","volume":"9","author":"Vaz","year":"2018","journal-title":"Front. Neurol."},{"issue":"1","key":"10.1016\/j.ntt.2021.107034_bb0550","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ntt.2008.09.003","article-title":"Developmental treatment with the dopamine D2\/3 agonist quinpirole selectively impairs spatial learning in the Morris water maze","volume":"31","author":"Vorhees","year":"2009","journal-title":"Neurotoxicol. Teratol."},{"issue":"17","key":"10.1016\/j.ntt.2021.107034_bb0555","doi-asserted-by":"crossref","first-page":"5981","DOI":"10.3390\/ijms21175981","article-title":"Chemical and genetic zebrafish models to define mechanisms of and treatments for dopaminergic neurodegeneration","volume":"21","author":"Wasel","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ntt.2021.107034_bb0560","series-title":"The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio)","author":"Westerfield","year":"2007"},{"issue":"31","key":"10.1016\/j.ntt.2021.107034_bb0565","doi-asserted-by":"crossref","first-page":"12764","DOI":"10.1073\/pnas.1210797109","article-title":"Pathway-specific control of reward learning and its flexibility via selective dopamine receptors in the nucleus accumbens","volume":"109","author":"Yawata","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ntt.2021.107034_bb0570","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.nlm.2013.05.004","article-title":"Role of nucleus accumbens dopamine receptor subtypes in the learning and expression of alcohol-seeking behavior","volume":"108","author":"Young","year":"2014","journal-title":"Neurobiol. Learn. Mem."},{"issue":"2","key":"10.1016\/j.ntt.2021.107034_bb0575","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/syn.20830","article-title":"A behavioral and molecular analysis of ketamine in zebrafish","volume":"65","author":"Zakhary","year":"2011","journal-title":"Synapse."}],"container-title":["Neurotoxicology and Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089203622100088X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089203622100088X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:28:42Z","timestamp":1760210922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089203622100088X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":116,"alternative-id":["S089203622100088X"],"URL":"https:\/\/doi.org\/10.1016\/j.ntt.2021.107034","relation":{},"ISSN":["0892-0362"],"issn-type":[{"value":"0892-0362","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-lasting behavioral effects of quinpirole exposure on zebrafish","name":"articletitle","label":"Article Title"},{"value":"Neurotoxicology and Teratology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ntt.2021.107034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107034"}}