{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:16:40Z","timestamp":1788869800344,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journals.elsevierhealth.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Nuclear Cardiology"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.nuclcard.2007.07.013","type":"journal-article","created":{"date-parts":[[2007,11,14]],"date-time":"2007-11-14T21:17:08Z","timestamp":1195075028000},"page":"827-834","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Side effect profile and tolerability of adenosine myocardial perfusion scintigraphy in patients with mild asthma or chronic obstructive pulmonary disease"],"prefix":"10.1016","volume":"14","author":[{"given":"Eliana","family":"Reyes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee Y.","family":"Loong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kshama","family":"Wechalekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Latus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantinos","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Richard","family":"Underwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 5","key":"10.1016\/j.nuclcard.2007.07.013_bib1","doi-asserted-by":"crossref","first-page":"v2","DOI":"10.1136\/hrt.2003.013581","article-title":"Diagnosis of coronary artery disease by radionuclide myocardial perfusion imaging","volume":"90","author":"Loong","year":"2004","journal-title":"Heart"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib2","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jaci.2004.05.071","article-title":"The role of endogenous and exogenous AMP in asthma and chronic obstructive pulmonary disease","volume":"114","author":"Van Den","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib3","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1378\/chest.128.4.1905","article-title":"Effects of aerosolized adenosine 5\u2019-triphosphate vs adenosine 5\u2019-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma","volume":"128","author":"Basoglu","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4065\/74.4.339","article-title":"Pulmonary function monitoring during adenosine myocardial perfusion scintigraphy in patients with chronic obstructive pulmonary disease","volume":"74","author":"Johnston","year":"1999","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib5","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1067\/mhj.2001.116070","article-title":"Is the dyspnea during adenosine cardiac stress test caused by bronchospasm?","volume":"142","author":"Balan","year":"2001","journal-title":"Am Heart J"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib6","unstructured":"Lenfant C. NHLBI guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. NHI Publication No. 97-4051, 1997."},{"key":"10.1016\/j.nuclcard.2007.07.013_bib7","first-page":"S77","article-title":"Standards for the diagnosis and management of patients with COPD. American Thoracic Society","volume":"152","author":"Celli","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"issue":"Suppl 1","key":"10.1016\/j.nuclcard.2007.07.013_bib8","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/heart.90.suppl_1.i1","article-title":"Procedure guidelines for radionuclide myocardial perfusion imaging","volume":"90","author":"Anagnostopoulos","year":"2004","journal-title":"Heart"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib9","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1161\/hc0402.102975","article-title":"Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association","volume":"105","author":"Cerqueira","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib10","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1183\/09031936.03.02582001","article-title":"Bronchial asthma causing symptoms suggestive of angina pectoris","volume":"21","author":"Kiss","year":"2003","journal-title":"Eur Respir J"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib11","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1378\/chest.128.4.2640","article-title":"Cardiovascular morbidity and mortality in COPD","volume":"128","author":"Huiart","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib12","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.amjcard.2006.02.064","article-title":"Safety of stress echocardiography (from the International Stress Echo Complication Registry)","volume":"98","author":"Varga","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib13","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/S0735-1097(00)01012-3","article-title":"Dobutamine stress myocardial perfusion imaging","volume":"36","author":"Geleijnse","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib14","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1016\/0735-1097(95)00011-R","article-title":"Adenosine combined with dynamic exercise for myocardial perfusion imaging","volume":"25","author":"Pennell","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib15","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2125.1983.tb01481.x","article-title":"Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects","volume":"15","author":"Cushley","year":"1983","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib16","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1016\/j.nuclcard.2006.08.011","article-title":"Stress protocols and tracers","volume":"13","author":"Henzlova","year":"2006","journal-title":"J Nucl Cardiol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib17","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1164\/ajrccm.163.7.2010145","article-title":"PC(20) adenosine 5\u2019-monophosphate is more closely associated with airway inflammation in asthma than PC(20) methacholine","volume":"163","author":"Van Den","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib18","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1046\/j.1365-2745.2003.01620.x","article-title":"Adenosine monophosphate bronchial provocation and the actions of asthma therapy","volume":"33","author":"Lee","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib19","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0735-1097(94)90424-3","article-title":"Safety profile of adenosine stress perfusion imaging: results from the Adenoscan Multicenter Trial Registry","volume":"23","author":"Cerqueira","year":"1994","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib20","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0031-6997(24)01511-4","article-title":"International Union of Pharmacology XXV: nomenclature and classification of adenosine receptors","volume":"53","author":"Fredholm","year":"2001","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib21","doi-asserted-by":"crossref","first-page":"338","DOI":"10.4049\/jimmunol.171.1.338","article-title":"Activation of murine lung mast cells by the adenosine A3 receptor","volume":"171","author":"Zhong","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib22","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1378\/chest.93.2.280","article-title":"Influence of infused adenosine on bronchial tone and bronchial reactivity in asthma","volume":"93","author":"Larsson","year":"1988","journal-title":"Chest"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib23","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1042\/cs0750429","article-title":"Absence of a late-phase response or increase in histamine responsiveness after bronchial provocation with adenosine 5\u2019-monophosphate in atopic and non-atopic asthma","volume":"75","author":"Phillips","year":"1988","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib24","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1165\/rcmb.2003-0118OC","article-title":"A(2B) adenosine receptors increase cytokine release by bronchial smooth muscle cells","volume":"30","author":"Zhong","year":"2004","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib25","doi-asserted-by":"crossref","first-page":"7726","DOI":"10.4049\/jimmunol.172.12.7726","article-title":"Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma","volume":"172","author":"Ryzhov","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib26","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0022-3565(24)29370-8","article-title":"Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists","volume":"298","author":"Gao","year":"2001","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib27","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1124\/jpet.103.053306","article-title":"Comparative profile of vasodilation by CVT-3146, a novel A2A receptor agonist, and adenosine in conscious dogs","volume":"307","author":"Zhao","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.nuclcard.2007.07.013_bib28","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1016\/j.jacc.2005.05.097","article-title":"Initial clinical experience with regadenoson, a novel selective A2A agonist for pharmacologic stress single-photon emission computed tomography myocardial perfusion imaging","volume":"46","author":"Hendel","year":"2005","journal-title":"J Am Coll Cardiol"}],"container-title":["Journal of Nuclear Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071358107005466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071358107005466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1016\/j.nuclcard.2007.07.013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T10:18:57Z","timestamp":1737541137000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071358107005466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S1071358107005466"],"URL":"https:\/\/doi.org\/10.1016\/j.nuclcard.2007.07.013","relation":{},"ISSN":["1071-3581"],"issn-type":[{"value":"1071-3581","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Side effect profile and tolerability of adenosine myocardial perfusion scintigraphy in patients with mild asthma or chronic obstructive pulmonary disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Nuclear Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nuclcard.2007.07.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 American Society of Nuclear Cardiology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}