{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:28:10Z","timestamp":1791142090275,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nuclear Medicine and Biology"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.nucmedbio.2005.02.004","type":"journal-article","created":{"date-parts":[[2005,5,6]],"date-time":"2005-05-06T19:28:59Z","timestamp":1115407739000},"page":"377-384","source":"Crossref","is-referenced-by-count":18,"title":["Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives"],"prefix":"10.1016","volume":"32","author":[{"given":"Marie-France","family":"Moreau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"Papon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Labarre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Moins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mich\u00e8le","family":"Borel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Bayle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Bouchon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Madelmont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nucmedbio.2005.02.004_bib1","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/oxfordjournals.bmb.a072978","article-title":"Epidemiology of malignant melanoma","volume":"51","author":"Boyle","year":"1995","journal-title":"Br Med Bull"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib2","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1056\/NEJMra041245","article-title":"Management of cutaneous melanoma","volume":"351","author":"Tsao","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib3","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1016\/S0959-8049(97)00358-4","article-title":"Management of cutaneous melanoma MO: state of the art and trends","volume":"33","author":"Rossi","year":"1997","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib4","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0140-6736(99)06002-X","article-title":"Radionuclide therapy","volume":"354","author":"Chatal","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib5","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1021\/cr9804386","article-title":"Therapeutic radiopharmaceuticals","volume":"99","author":"Volkert","year":"1999","journal-title":"Chem Rev"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib6","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1007\/s002590050302","article-title":"Early detection of melanoma metastases with radioiodinated methylene blue","volume":"25","author":"Link","year":"1998","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib7","first-page":"1573","article-title":"Synthesis and evaluation of new iodine-125 radiopharmaceuticals as potential tracers for malignant melanoma","volume":"32","author":"Michelot","year":"1991","journal-title":"J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib8","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s002590050416","article-title":"Evaluation in mice of some iodinated melanoma imaging agents using cryosectioning and multiwire proportional counting","volume":"26","author":"Labarre","year":"1999","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0969-8051(93)90138-K","article-title":"An improved synthesis of N-(diethylaminoethyl)-4-[125I]iodobenzamide: a potential ligand for imaging malignant melanoma","volume":"20","author":"John","year":"1993","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib10","first-page":"1260","article-title":"Phase II scintigraphic clinical trial of malignant melanoma and metastases with iodine-123-N-(2-diethylaminoethyl 4-iodobenzamide)","volume":"34","author":"Michelot","year":"1993","journal-title":"J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib11","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1034\/j.1600-0420.1998.760110.x","article-title":"Clinical study of [123I]-N-(2-diethylaminoethyl)-4-iodobenzamide in the diagnosis of primary and metastatic ocular melanoma","volume":"76","author":"Bacin","year":"1998","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib12","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1007\/s00259-002-0971-6","article-title":"123I-N-(2-diethylaminoethyl)-2-iodobenzamide: a potential imaging agent for cutaneous melanoma staging","volume":"29","author":"Moins","year":"2002","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib13","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/0969-8051(95)00020-X","article-title":"Synthesis, radiolabeling and preliminary evaluation in mice of some (N-diethylaminoethyl)-4-iodobenzamide derivatives as melanoma imaging agents","volume":"22","author":"Moreau","year":"1995","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib14","first-page":"1865","article-title":"Structure, distribution, relationship of iodine-123-iodobenzamides as tracers for the detection of melanotic melanoma","volume":"37","author":"Brandau","year":"1996","journal-title":"J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib15","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0969-8051(97)00024-3","article-title":"Radioiodinated N-(alkylaminoalkyl)-substituted 4-methoxy-, 4-hydroxy-, and 4-aminobenzamides: biological investigations for the improvement of melanoma-imaging agents","volume":"24","author":"Mohammed","year":"1997","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib16","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1021\/jm991079p","article-title":"Radioiodinated N-(2-diethylaminoethyl) benzamide derivatives with high melanoma uptake: structure\u2013affinity relationships, metabolic fate and intracellular localization","volume":"43","author":"Eisenhut","year":"2000","journal-title":"J Med Chem"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib17","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/S0969-8051(01)00242-6","article-title":"Synthesis, characterization and comparative biodistribution study of a new series of p-iodine-125 benzamides as potential melanoma imaging agents","volume":"28","author":"Moins","year":"2001","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00008390-200204000-00003","article-title":"Melanin affinity of N-(2-diethylaminoethyl)-4-iodobenzamide, an effective melanoma imaging agent","volume":"12","author":"Labarre","year":"2002","journal-title":"Melanoma Res"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib19","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1475-925X-3-10","article-title":"Ultra-structural cell distribution of the melanoma marker iodobenzamide: improved potentiality of SIMS imaging in life sciences","volume":"3","author":"Guerquin-Kern","year":"2004","journal-title":"Biomed Eng Online"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib20","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0969-8051(98)00046-8","article-title":"In vitro studies on the cellular uptake of melanoma imaging aminoalkyl\u2013iodobenzamide derivatives (ABA)","volume":"26","author":"Dittmann","year":"1999","journal-title":"Nucl Med Biol"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1748-1716.1981.tb06806.x","article-title":"Binding of 14C-spermidine to melanin in vivo and in vitro","volume":"112","author":"Tj\u00e4lve","year":"1981","journal-title":"Acta Physiol Scand"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1600-0749.1993.tb00591.x","article-title":"Interaction between chemicals and melanin","volume":"6","author":"Larsson","year":"1993","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib23","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1034\/j.1600-0749.2000.130412.x","article-title":"Melanins, melanogenesis and melanocytes: looking at their functional significance from the chemist's viewpoint","volume":"13","author":"Prota","year":"2000","journal-title":"Pigment Cell Res"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib24","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/S0040-4020(99)01082-0","article-title":"Homologation of polyamines in the rapid synthesis of lipospermine conjugates and related lipoplexes","volume":"56","author":"Geall","year":"2000","journal-title":"Tetrahedron"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib25","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1021\/jo50015a017","article-title":"The reduction of acid amides with lithium aluminium hydride","volume":"18","author":"Micovic","year":"1953","journal-title":"J Org Chem"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib26","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s002590050201","article-title":"A new quantitative method to evaluate the biodistribution of a radiolabeled tracer for melanoma using whole-body cryosectioning and a gaseous detection: comparison with conventional tissue combustion technology","volume":"25","author":"Labarre","year":"1998","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2005.02.004_bib27","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1021\/jo00805a022","article-title":"The formic acid\u2013formaldehyde methylation of amines","volume":"36","author":"Pine","year":"1971","journal-title":"J Org Chem"}],"container-title":["Nuclear Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805105000545?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805105000545?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T05:20:21Z","timestamp":1550467221000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969805105000545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0969805105000545"],"URL":"https:\/\/doi.org\/10.1016\/j.nucmedbio.2005.02.004","relation":{},"ISSN":["0969-8051"],"issn-type":[{"value":"0969-8051","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}