{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:20:49Z","timestamp":1789417249616,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","nucmedbio.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nuclear Medicine and Biology"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.nucmedbio.2014.07.007","type":"journal-article","created":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T23:36:00Z","timestamp":1406849760000},"page":"848-855","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["In vivo bio-distribution and homing of endothelial outgrowth cells in a tumour model"],"prefix":"10.1016","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6384-2622","authenticated-orcid":false,"given":"Lotte B.","family":"Bertelsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Hagensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Busk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne S.","family":"Knudsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Falborg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne K.","family":"M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Horsman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"St\u00f8dkilde-J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.nucmedbio.2014.07.007_bb0005","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/scrt114","article-title":"Systematic assessment in an animal model of the angiogenic potential of different human cell sources for therapeutic revascularization","volume":"3","author":"Barclay","year":"2012","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.nucmedbio.2014.07.007_bb0010","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1582-4934.2008.00598.x","article-title":"Endothelial progenitor cells: identity defined?","volume":"13","author":"Timmermans","year":"2009","journal-title":"J Cell Mol Med"},{"issue":"5","key":"10.1016\/j.nucmedbio.2014.07.007_bb0015","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1182\/blood-2005-04-1509","article-title":"Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells","volume":"106","author":"Ingram","year":"2005","journal-title":"Blood"},{"issue":"7","key":"10.1016\/j.nucmedbio.2014.07.007_bb0020","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1161\/ATVBAHA.107.144972","article-title":"Endothelial outgrowth cells are not derived from CD133+ cells or CD45+ hematopoietic precursors","volume":"27","author":"Timmermans","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"10.1016\/j.nucmedbio.2014.07.007_bb0025","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/stem.1280","article-title":"Late outgrowth endothelial cells resemble mature endothelial cells and are not derived from bone marrow","volume":"31","author":"Tura","year":"2013","journal-title":"Stem Cells"},{"issue":"4","key":"10.1016\/j.nucmedbio.2014.07.007_bb0030","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1161\/01.RES.0000137877.89448.78","article-title":"Endothelial progenitor cells: characterization and role in vascular biology","volume":"95","author":"Urbich","year":"2004","journal-title":"Circ Res"},{"issue":"3","key":"10.1016\/j.nucmedbio.2014.07.007_bb0035","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.mvr.2010.02.011","article-title":"EPCs and pathological angiogenesis: when good cells go bad","volume":"79","author":"Li","year":"2010","journal-title":"Microvasc Res"},{"issue":"12","key":"10.1016\/j.nucmedbio.2014.07.007_bb0040","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1101\/gad.436307","article-title":"Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization","volume":"21","author":"Nolan","year":"2007","journal-title":"Genes Dev"},{"issue":"1","key":"10.1016\/j.nucmedbio.2014.07.007_bb0045","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/cancers5010205","article-title":"Blood outgrowth endothelial cells increase tumor growth rates and modify tumor physiology: relevance for therapeutic targeting","volume":"5","author":"Pagan","year":"2013","journal-title":"Cancers (Basel)"},{"issue":"5794","key":"10.1016\/j.nucmedbio.2014.07.007_bb0050","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1126\/science.1127592","article-title":"Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors","volume":"313","author":"Shaked","year":"2006","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.nucmedbio.2014.07.007_bb0055","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1158\/2159-8290.CD-11-0171","article-title":"Reversing resistance to vascular-disrupting agents by blocking late mobilization of circulating endothelial progenitor cells","volume":"2","author":"Taylor","year":"2012","journal-title":"Cancer Discov"},{"issue":"1","key":"10.1016\/j.nucmedbio.2014.07.007_bb0060","first-page":"50","article-title":"The definition of EPCs and other bone marrow cells contributing to neoangiogenesis and tumor growth: is there common ground for understanding the roles of numerous marrow-derived cells in the neoangiogenic process?","volume":"1796","author":"Yoder","year":"2009","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"10.1016\/j.nucmedbio.2014.07.007_bb0065","first-page":"512","article-title":"111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model","volume":"45","author":"Brenner","year":"2004","journal-title":"J Nucl Med"},{"issue":"5","key":"10.1016\/j.nucmedbio.2014.07.007_bb0070","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00259-006-0275-3","article-title":"Indium-111 oxine labelling affects the cellular integrity of haematopoietic progenitor cells","volume":"34","author":"Nowak","year":"2007","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"5","key":"10.1016\/j.nucmedbio.2014.07.007_bb0075","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S1473-3099(01)00146-3","article-title":"The role of nuclear medicine in infection and inflammation","volume":"1","author":"Becker","year":"2001","journal-title":"Lancet Infect Dis"},{"issue":"16","key":"10.1016\/j.nucmedbio.2014.07.007_bb0080","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1161\/01.CIR.0000062649.63838.C9","article-title":"Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling","volume":"107","author":"Aicher","year":"2003","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.nucmedbio.2014.07.007_bb0085","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2967\/jnumed.109.069732","article-title":"Comparison of initial cell retention and clearance kinetics after subendocardial or subepicardial injections of endothelial progenitor cells in a canine myocardial infarction model","volume":"51","author":"Mitchell","year":"2010","journal-title":"J Nucl Med"},{"issue":"11","key":"10.1016\/j.nucmedbio.2014.07.007_bb0090","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/0360-3016(80)90008-5","article-title":"Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo","volume":"6","author":"Overgaard","year":"1980","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5302","key":"10.1016\/j.nucmedbio.2014.07.007_bb0095","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1126\/science.275.5302.964","article-title":"Isolation of putative progenitor endothelial cells for angiogenesis","volume":"275","author":"Asahara","year":"1997","journal-title":"Science"},{"issue":"7","key":"10.1016\/j.nucmedbio.2014.07.007_bb0100","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1161\/CIRCULATIONAHA.109.885459","article-title":"Circulating endothelial progenitor cells do not contribute to plaque endothelium in murine atherosclerosis","volume":"121","author":"Hagensen","year":"2010","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.nucmedbio.2014.07.007_bb0105","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/sj.gt.3301723","article-title":"Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors","volume":"9","author":"Rafii","year":"2002","journal-title":"Gene Ther"},{"issue":"11","key":"10.1016\/j.nucmedbio.2014.07.007_bb0110","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/nrc1971","article-title":"The multifaceted circulating endothelial cell in cancer: towards marker and target identification","volume":"6","author":"Bertolini","year":"2006","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"10.1016\/j.nucmedbio.2014.07.007_bb0115","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.ijrobp.2007.10.012","article-title":"Preclinical studies to predict efficacy of vascular changes induced by combretastatin a-4 disodium phosphate in patients","volume":"70","author":"Nielsen","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"10","key":"10.1016\/j.nucmedbio.2014.07.007_bb0120","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1161\/CIRCULATIONAHA.105.537480","article-title":"Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction","volume":"112","author":"Kraitchman","year":"2005","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.nucmedbio.2014.07.007_bb0125","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1007\/s00259-006-0093-7","article-title":"Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation","volume":"33","author":"Bindslev","year":"2006","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"2","key":"10.1016\/j.nucmedbio.2014.07.007_bb0130","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.transproceed.2006.12.019","article-title":"Stem cell transplantation: the lung barrier","volume":"39","author":"Schrepfer","year":"2007","journal-title":"Transplant Proc"},{"issue":"7","key":"10.1016\/j.nucmedbio.2014.07.007_bb0135","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0969-8051(99)00057-8","article-title":"Localization of indium-111 in human malignant tumor xenografts and control by chelators","volume":"26","author":"Watanabe","year":"1999","journal-title":"Nucl Med Biol"},{"issue":"1","key":"10.1016\/j.nucmedbio.2014.07.007_bb0140","first-page":"33","article-title":"Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression","volume":"1796","author":"Gao","year":"2009","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"10.1016\/j.nucmedbio.2014.07.007_bb0145","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ijcard.2008.10.009","article-title":"Paracrine effects of CD34 progenitor cells on angiogenic endothelial sprouting","volume":"139","author":"Scheubel","year":"2010","journal-title":"Int J Cardiol"},{"issue":"12","key":"10.1016\/j.nucmedbio.2014.07.007_bb0150","doi-asserted-by":"crossref","first-page":"e82085","DOI":"10.1371\/journal.pone.0082085","article-title":"Endothelial progenitor cells promote directional three-dimensional endothelial network formation by secreting vascular endothelial growth factor","volume":"8","author":"Abe","year":"2013","journal-title":"PLoS ONE"}],"container-title":["Nuclear Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805114004582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805114004582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T03:25:21Z","timestamp":1538364321000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969805114004582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0969805114004582"],"URL":"https:\/\/doi.org\/10.1016\/j.nucmedbio.2014.07.007","relation":{},"ISSN":["0969-8051"],"issn-type":[{"value":"0969-8051","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vivo bio-distribution and homing of endothelial outgrowth cells in a tumour model","name":"articletitle","label":"Article Title"},{"value":"Nuclear Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nucmedbio.2014.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}