{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T06:07:47Z","timestamp":1760854067328,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000769","name":"University of Oxford","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nuclear Medicine and Biology"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.nucmedbio.2019.07.007","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T02:13:10Z","timestamp":1563415990000},"page":"49-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA"],"prefix":"10.1016","volume":"72-73","author":[{"given":"Mary-Ann Elvina","family":"Xavier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shihui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen H.","family":"Leppla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"Cornelissen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0005","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/nrc2228","article-title":"Emerging roles of proteases in tumour suppression","volume":"7","author":"L\u00f3pez-Ot\u00edn","year":"2007","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0010","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrc745","article-title":"New functions for the matrix metalloproteinases in cancer progression","volume":"2","author":"Egeblad","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0015","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cell.2010.03.015","article-title":"Matrix metalloproteinases: regulators of the tumor microenvironment","volume":"141","author":"Kessenbrock","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0020","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1126\/science.1067100","article-title":"Matrix metalloproteinase inhibitors and cancer\u2014trials and tribulations","volume":"295","author":"Coussens","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0025","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1349-7006.2004.tb03166.x","article-title":"Inhibition of lymphangiogenesis-related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproteinase inhibitor MMI270","volume":"95","author":"Nakamura","year":"2004","journal-title":"Cancer Sci"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0030","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1023\/A:1006500406240","article-title":"Matrix-degrading proteinases are shed in membrane vesicles by ovarian cancer cells in vivo and in vitro","volume":"17","author":"Dolo","year":"1999","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0035","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1002\/jcb.21923","article-title":"Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes","volume":"105","author":"Hakulinen","year":"2008","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0040","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1200\/JCO.2009.23.5556","article-title":"Matrix metalloproteinases as novel biomarker s and potential therapeutic targets in human cancer","volume":"27","author":"Roy","year":"2009","journal-title":"JCO"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0045","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1101\/gad.1047403","article-title":"Molecular imaging in living subjects: seeing fundamental biological processes in a new light","volume":"17","author":"Massoud","year":"2003","journal-title":"Genes Dev"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0050","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.2174\/1381612811319250011","article-title":"Probes for Non-invasive Matrix Metalloproteinase-targeted Imaging with PET and SPECT","volume":"19","author":"Matusiak","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0055","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s10555-008-9152-9","article-title":"Imaging matrix metalloproteinases in cancer","volume":"27","author":"Scherer","year":"2008","journal-title":"Cancer Metastasis Rev"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0060","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/cmmi.1555","article-title":"A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging","volume":"9","author":"Lebel","year":"2014","journal-title":"Contrast Media Mol Imaging"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0065","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1007\/s13277-013-0842-8","article-title":"Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets","volume":"34","author":"Hadler-Olsen","year":"2013","journal-title":"Tumor Biol."},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0070","first-page":"6061","article-title":"Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin","volume":"60","author":"Liu","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.nucmedbio.2019.07.007","article-title":"Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins","author":"Xavier","year":"2019","journal-title":"J Nucl Med"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0080","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.biochem.75.103004.142728","article-title":"Anthrax toxin: receptor binding, internalization, pore formation, and translocation","volume":"76","author":"Young","year":"2007","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0085","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.jmb.2004.09.067","article-title":"Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin","volume":"344","author":"Krantz","year":"2004","journal-title":"J Mol Biol"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0090","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1126\/science.280.5364.734","article-title":"Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor","volume":"280","author":"Duesbery","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0095","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1158\/1535-7163.MCT-09-0694","article-title":"Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma","volume":"9","author":"Alfano","year":"2010","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0183346","article-title":"Genome engineering in Bacillus anthracis using tyrosine site-specific recombinases","volume":"12","author":"Pomerantsev","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0105","first-page":"145","article-title":"Secondary structure of proteins through circular dichroism spectroscopy","volume":"17","author":"W C Johnson","year":"1988"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0110","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1083\/jcb.200312072","article-title":"Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway","volume":"166","author":"Abrami","year":"2004","journal-title":"J Cell Biol"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0115","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1083\/jcb.200211018","article-title":"Anthrax toxin triggers endocytosis of its receptor via a lipid raft\u2013mediated clathrin-dependent process","volume":"160","author":"Abrami","year":"2003","journal-title":"J Cell Biol"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0120","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.tim.2004.12.004","article-title":"Anthrax toxin: the long and winding road that leads to the kill","volume":"13","author":"Abrami","year":"2005","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0125","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1021\/bc200680x","article-title":"DOTAGA-Trastuzumab. A new antibody conjugate targeting HER2\/Neu antigen for diagnostic purposes","volume":"23","author":"Moreau","year":"2012","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0130","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1007\/s00259-003-1255-5","article-title":"DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals","volume":"30","author":"Wild","year":"2003","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0135","doi-asserted-by":"crossref","first-page":"21555","DOI":"10.1073\/pnas.0905880106","article-title":"Lethal factor unfolding is the most force-dependent step of anthrax toxin translocation","volume":"106","author":"Thoren","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nucmedbio.2019.07.007_bb0140","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1002\/pro.5560021002","article-title":"Disulfide bonds and the stability of globular proteins. Protein science: a publication of the","volume":"2","author":"Betz","year":"1993","journal-title":"Protein Soc."}],"container-title":["Nuclear Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805119301027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0969805119301027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T04:28:33Z","timestamp":1760848113000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0969805119301027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":28,"alternative-id":["S0969805119301027"],"URL":"https:\/\/doi.org\/10.1016\/j.nucmedbio.2019.07.007","relation":{},"ISSN":["0969-8051"],"issn-type":[{"type":"print","value":"0969-8051"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA","name":"articletitle","label":"Article Title"},{"value":"Nuclear Medicine and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nucmedbio.2019.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}