{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:57:41Z","timestamp":1790683061209,"version":"4.1.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["nmcd-journal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.numecd.2018.06.013","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T18:15:51Z","timestamp":1529691351000},"page":"965-972","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"title":["Thiamine deficiency and cardiovascular disorders"],"prefix":"10.1016","volume":"28","author":[{"given":"E.S.","family":"Eshak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.E.","family":"Arafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib1","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1021\/bi401618y","article-title":"Thiamin function, metabolism, uptake, and transport","volume":"53","author":"Manzetti","year":"2014","journal-title":"Biochemistry"},{"key":"10.1016\/j.numecd.2018.06.013_bib2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/0884533611426149","article-title":"Thiamine in nutrition therapy","volume":"27","author":"Sriram","year":"2012","journal-title":"Nutr Clin Pract"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.013_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3177\/jnsv.36.4-SupplementI_S17","article-title":"Cooking losses of thiamin in food and its nutritional significance","volume":"36","author":"Kimura","year":"1990","journal-title":"J Nutr Sci Vitaminol (Tokyo)"},{"key":"10.1016\/j.numecd.2018.06.013_bib4","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/ecam\/nek009","article-title":"A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives","volume":"3","author":"Lonsdale","year":"2006","journal-title":"Evid Based Complement Alternat Med"},{"issue":"4","key":"10.1016\/j.numecd.2018.06.013_bib5","first-page":"184","article-title":"Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy","volume":"10","author":"Zenuk","year":"2003","journal-title":"Can J Clin Pharmacol"},{"key":"10.1016\/j.numecd.2018.06.013_bib6","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1024\/0300-9831.71.4.217","article-title":"The thiamine status of adult humans depends on carbohydrate intake","volume":"71","author":"Elmadfa","year":"2001","journal-title":"Int J Vitam Nutr Res"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.013_bib7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1152\/ajprenal.00266.2010","article-title":"Unraveling the pathophysiology of alcohol-induced thiamin deficiency","volume":"299","author":"Kiela","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.numecd.2018.06.013_bib8","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/chf.12037","article-title":"Thiamine supplementation for the treatment of heart failure: a review of the literature","volume":"19","author":"DiNicolantonio","year":"2013","journal-title":"Congest Heart Fail"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.013_bib9","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ijcard.2012.10.046","article-title":"Mortality from ischaemic heart disease by country, region, and age: statistics from World Health Organisation and United Nations","volume":"168","author":"Finegold","year":"2012","journal-title":"Int J Cardiol"},{"issue":"9733","key":"10.1016\/j.numecd.2018.06.013_bib10","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1016\/S0140-6736(10)60484-9","article-title":"Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies","volume":"375","author":"Sarwar","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.numecd.2018.06.013_bib11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.diabres.2014.09.058","article-title":"Vitamin B status in patients with type 2 diabetes mellitus with and without incipient nephropathy","volume":"107","author":"Nix","year":"2015","journal-title":"Diabetes Res Clin Pract"},{"issue":"10","key":"10.1016\/j.numecd.2018.06.013_bib12","first-page":"13483","article-title":"Biochemical changes correlated with blood thiamine and its phosphate esters levels in patients with diabetes type 1 (DMT1)","volume":"8","author":"Al-Daghri","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"10.1016\/j.numecd.2018.06.013_bib13","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1007\/s00125-007-0771-4","article-title":"High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease","volume":"50","author":"Thornalley","year":"2007","journal-title":"Diabetologia"},{"key":"10.1016\/j.numecd.2018.06.013_bib14","first-page":"100","article-title":"Effect of insulin on thiamine intestinal transport in rat everted jejunal sacs","volume":"493","author":"Patrini","year":"1996","journal-title":"J Physiol"},{"key":"10.1016\/j.numecd.2018.06.013_bib15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1152\/ajpgi.00092.2009","article-title":"Pancreatic beta cells and islets take up thiamin by a regulated Carrier-mediated process: studies using mice and human pancreatic preparations","volume":"297","author":"Mee","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"24","key":"10.1016\/j.numecd.2018.06.013_bib16","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.3748\/wjg.v16.i24.2978","article-title":"Small intestinal bacterial overgrowth syndrome","volume":"16","author":"Bures","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.numecd.2018.06.013_bib17","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s00125-008-1224-4","article-title":"High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study","volume":"52","author":"Rabbani","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.numecd.2018.06.013_bib18","first-page":"233","article-title":"Effect of thiamine therapy on risk factors in type 2 diabetes","volume":"3","author":"Alam","year":"2012","journal-title":"J Diabetes Metab"},{"key":"10.1016\/j.numecd.2018.06.013_bib19","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s00394-010-0123-x","article-title":"Effect of thiamine administration on metabolic profile, cytokines and inflammatory markers in drug-na\u00efve patients with type 2 diabetes","volume":"50","author":"Gonz\u00e1lez-Ortiz","year":"2011","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.numecd.2018.06.013_bib20","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0140-6736(09)60318-4","article-title":"Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies","volume":"373","author":"Whitlock","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.numecd.2018.06.013_bib21","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1097\/EDE.0b013e3181b5f520","article-title":"Weight change, initial BMI, and mortality among middle- and older-aged adults","volume":"20","author":"Myrskyl\u00e4","year":"2009","journal-title":"Epidemiology"},{"key":"10.1016\/j.numecd.2018.06.013_bib22","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.soard.2005.08.003","article-title":"Preoperative thiamine deficiency in obese population undergoing laparoscopic bariatric surgery","volume":"1","author":"Carrodeguas","year":"2005","journal-title":"Surg Obes Relat Dis"},{"key":"10.1016\/j.numecd.2018.06.013_bib23","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.gassur.2006.03.004","article-title":"Preoperative nutritional status of patients undergoing roux-en-Y gastric bypass for morbid obesity","volume":"10","author":"Flancbaum","year":"2006","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.numecd.2018.06.013_bib24","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.nutres.2016.11.012","article-title":"Prevalence of clinical thiamine deficiency in individuals with medically complicated obesity","volume":"37","author":"Nath","year":"2017","journal-title":"Nutr Res"},{"key":"10.1016\/j.numecd.2018.06.013_bib25","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00592-013-0460-3","article-title":"Very severely obese patients have a high prevalence of type 2 diabetes mellitus and cardiovascular disease","volume":"50","author":"Vinciguerra","year":"2013","journal-title":"Acta Diabetol"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.013_bib26","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000353245","article-title":"Constipation in patients with thiamine deficiency after Roux-en-Y gastric bypass surgery","volume":"88","author":"Shah","year":"2013","journal-title":"Digestion"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib27","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.nutres.2008.03.002","article-title":"Small intestinal bacterial overgrowth and thiamine deficiency after Roux-en-Y gastric bypass surgery in obese patients","volume":"28","author":"Lakhani","year":"2008","journal-title":"Nutr Res"},{"key":"10.1016\/j.numecd.2018.06.013_bib28","doi-asserted-by":"crossref","first-page":"103472","DOI":"10.5402\/2012\/103472","article-title":"The malnutrition of obesity: micronutrient deficiencies that promote diabetes","volume":"2012","author":"Via","year":"2012","journal-title":"ISRN Endocrinol"},{"key":"10.1016\/j.numecd.2018.06.013_bib29","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/09637480701600302","article-title":"Increasing consumption of breakfast cereal improves thiamine status in overweight\/obese women following a hypocaloric diet","volume":"60","author":"Ortega","year":"2009","journal-title":"Int J Food Sci Nutr"},{"key":"10.1016\/j.numecd.2018.06.013_bib30","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.diabres.2012.09.032","article-title":"Increased thiamine intake may be required to maintain thiamine status during weight loss in patients with type 2 diabetes","volume":"98","author":"Keogh","year":"2012","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.numecd.2018.06.013_bib31","first-page":"183","article-title":"Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome","volume":"1","author":"Hadi","year":"2005","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.numecd.2018.06.013_bib32","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1161\/01.CIR.0000017493.03108.1C","article-title":"Prospective study of C-reactive protein, homocysteine, and plasma lipid levels as predictors of sudden cardiac death","volume":"105","author":"Albert","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.numecd.2018.06.013_bib33","doi-asserted-by":"crossref","first-page":"104","DOI":"10.7326\/0003-4819-11-1-104","article-title":"The nature of the cardiovascular disturbances in nutritional deficiency states (beriberi)","volume":"11","author":"Weiss","year":"1937","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.numecd.2018.06.013_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s100169910007","article-title":"Thiamine (vitamin B1) protects against glucose and insulin mediated proliferation of human infragenicular arterial smooth muscle cells","volume":"14","author":"Avena","year":"2000","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.numecd.2018.06.013_bib35","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1007\/s001250050568","article-title":"Thiamine corrects delayed replication and decreases production of lactate and advanced glycation end-products in bovine retinal and human umbilical vein endothelial cells cultured under high glucose conditions","volume":"39","author":"La Selva","year":"1996","journal-title":"Diabetologia"},{"key":"10.1016\/j.numecd.2018.06.013_bib36","first-page":"263","article-title":"Beriberi heart disease: a case report describing the haemodynamic features","volume":"68","author":"Ayzenberg","year":"1985","journal-title":"S Afr Med J"},{"key":"10.1016\/j.numecd.2018.06.013_bib37","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1161\/01.CIR.58.3.566","article-title":"Fulminant beriberi heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms","volume":"58","author":"Attas","year":"1978","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib38","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/S10016-006-9055-6","article-title":"Thiamine (Vitamin B1) improves endothelium-dependent vasodilatation in the presence of hyperglycemia","volume":"20","author":"Arora","year":"2006","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.numecd.2018.06.013_bib39","first-page":"968761","article-title":"Benfotiamine counteracts smoking-induced vascular dysfunction in healthy smokers","volume":"2012","author":"Stirban","year":"2012","journal-title":"Int J Vasc Med"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.013_bib40","first-page":"340","article-title":"Thiamine deficiency and its correlation with dyslipidaemia in diabetics with microalbuminuria","volume":"63","author":"Waheed","year":"2013","journal-title":"J Pak Med Assoc"},{"key":"10.1016\/j.numecd.2018.06.013_bib41","first-page":"412","article-title":"Vitamins, lipids and lipoproteins in a healthy elderly population","volume":"53","author":"Hooper","year":"1983","journal-title":"Int J Vitamin Nutr Res"},{"key":"10.1016\/j.numecd.2018.06.013_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/CMED.S13573","article-title":"Metabolic benefits of six-month thiamine supplementation in patients with and without diabetes mellitus type 2","volume":"7","author":"Al-Attas","year":"2014","journal-title":"Clin Med Insights Endocrinol Diabetes"},{"key":"10.1016\/j.numecd.2018.06.013_bib43","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0002-8703(38)90857-9","article-title":"Electrocardiographic manifestations and the cardiac effect of drugs in vitamin B-1 deficiency in rats","volume":"15","author":"Weiss","year":"1938","journal-title":"Amer Heart J"},{"key":"10.1016\/j.numecd.2018.06.013_bib44","first-page":"479","article-title":"Changes in myocardial thiamine in arteriosclerotic and non-arteriosclerotic rats subjected to isoprenaline induced myocardial infarction","volume":"54","author":"Wexler","year":"1973","journal-title":"Br J Exp Pathol"},{"key":"10.1016\/j.numecd.2018.06.013_bib45","first-page":"721","article-title":"Beneficial effects of cocarboxylase in the treatment of experimental myocardial infarction in dogs","volume":"53","author":"Larrieu","year":"1987","journal-title":"Am Surg"},{"key":"10.1016\/j.numecd.2018.06.013_bib46","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S1016-8478(23)13093-7","article-title":"Thiamine attenuates hypoxia-induced cell death in cultured neonatal rat cardiomyo-cytes","volume":"18","author":"Shin","year":"2004","journal-title":"Mol Cells"},{"key":"10.1016\/j.numecd.2018.06.013_bib47","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1746-1596-6-8","article-title":"Cardiac beriberi: morphological findings in two fatal cases","volume":"6","author":"Bello","year":"2011","journal-title":"Diagn Pathol"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib48","first-page":"319","article-title":"Changes in blood pressure and heart rate following dietary-induced thiamine deficiency in muricide rats","volume":"11","author":"Onodera","year":"1991","journal-title":"Yakubutsu Seishin Kodo"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib49","first-page":"428","article-title":"Stupor, bradycardia, hypotension and hypothermia. A presentation of Wernicke's encephalopathy with rapid response to thiamine","volume":"121","author":"Ackerman","year":"1974","journal-title":"West J Med"},{"issue":"6","key":"10.1016\/j.numecd.2018.06.013_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5830\/CVJA-2014-053","article-title":"A case of shoshin beriberi presenting as cardiogenic shock with diffuse ST-segment elevation, which dramatically improved after a single dose of thiamine","volume":"25","author":"Kim","year":"2014","journal-title":"Cardiovasc J Afr"},{"issue":"4","key":"10.1016\/j.numecd.2018.06.013_bib51","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jemermed.2008.03.040","article-title":"Shoshin beriberi mimicking a high-risk non-ST-segment elevation acute coronary syndrome with cardiogenic shock: when the arteries are not guilty","volume":"41","author":"Loma-Osorio","year":"2011","journal-title":"J Emerg Med"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.013_bib52","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ihj.2016.07.015","article-title":"Shoshin beriberi-thiamine responsive pulmonary hypertension in exclusively breastfed infants: a study from northern India","volume":"69","author":"Bhat","year":"2017","journal-title":"Indian Heart J"},{"key":"10.1016\/j.numecd.2018.06.013_bib53","first-page":"41","article-title":"Wernicke's encephalopathy: the clinical features and their probable relationship to vitamin B deficiency","volume":"10","author":"Campbell","year":"1941","journal-title":"Q J Med"},{"key":"10.1016\/j.numecd.2018.06.013_bib54","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1161\/STROKEAHA.116.013048","article-title":"Thiamine deficiency presenting as intraventricular hemorrhage","volume":"47","author":"Al-Bayati","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.numecd.2018.06.013_bib55","first-page":"518","article-title":"Immediate recovery of an \"ischemic stroke\" following treatment with intravenous thiamine (vitamin B1)","volume":"16","author":"Blum","year":"2014","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.numecd.2018.06.013_bib56","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1089\/acm.2013.0461","article-title":"High-dose thiamine improves fatigue after stroke: a report of three cases","volume":"20","author":"Costantini","year":"2014","journal-title":"J Altern Complement Med"},{"key":"10.1016\/j.numecd.2018.06.013_bib57","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.neuro.2016.10.014","article-title":"Brain endothelial dysfunction following pyrithiamine induced thiamine deficiency in the rat","volume":"57","author":"Sarkar","year":"2016","journal-title":"Neurotoxicology"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.013_bib58","first-page":"6","article-title":"The economic burden of heart failure","volume":"23","author":"O'Connell","year":"2000","journal-title":"Clin Cardiol"},{"issue":"12","key":"10.1016\/j.numecd.2018.06.013_bib59","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.cardfail.2015.10.005","article-title":"Determining the role of thiamine deficiency in systolic heart failure: a meta-analysis and systematic review","volume":"21","author":"Jain","year":"2015","journal-title":"J Card Fail"},{"issue":"4","key":"10.1016\/j.numecd.2018.06.013_bib60","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1527-5299.2007.06260.x","article-title":"Loop diuretic therapy, thiamine balance, and heart failure","volume":"13","author":"Sica","year":"2007","journal-title":"Congest Heart Fail"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.013_bib61","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/ageing\/29.2.111","article-title":"Is thiamine deficiency in elderly people related to age or co-morbidity?","volume":"29","author":"Wilkinson","year":"2000","journal-title":"Age Ageing"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.013_bib62","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/ageing\/29.2.99","article-title":"Thiamine deficiency in elderly people","volume":"29","author":"O'Keeffe","year":"2000","journal-title":"Age Ageing"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.013_bib63","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/ageing\/21.1.67","article-title":"Thiamine status of elderly patients with cardiac failure","volume":"21","author":"Kwok","year":"1992","journal-title":"Age Ageing"},{"issue":"11","key":"10.1016\/j.numecd.2018.06.013_bib64","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1056\/NEJMra063052","article-title":"The failing heart; an engine out of fuel","volume":"356","author":"Neubauer","year":"2007","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.numecd.2018.06.013_bib65","doi-asserted-by":"crossref","first-page":"e13616","DOI":"10.1371\/journal.pone.0013616","article-title":"Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells","volume":"5","author":"Gangolf","year":"2010","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.013_bib66","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0002-9343(91)90007-K","article-title":"Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study","volume":"91","author":"Seligmann","year":"1991","journal-title":"Am J Med"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.013_bib67","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0002-9343(99)80349-0","article-title":"Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy","volume":"98","author":"Shimon","year":"1995","journal-title":"Am J Med"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.013_bib68","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00392-011-0376-2","article-title":"Thiamine supplementation in symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled, cross-over pilot study","volume":"101","author":"Schoenenberger","year":"2012","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.numecd.2018.06.013_bib69","first-page":"495","article-title":"Effects of thiamine on cardiac function in patients with systolic heart failure: systematic review and metaanalysis of randomized, double-blind, placebo-controlled trials","volume":"13","author":"DiNicolantonio","year":"2013","journal-title":"Ochsner J"},{"key":"10.1016\/j.numecd.2018.06.013_bib70","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0002-8703(96)90304-X","article-title":"Effects of cardiac rehabilitation and exercise training programs on depression in patients after major coronary events","volume":"132","author":"Milani","year":"1996","journal-title":"Am Heart J"},{"key":"10.1016\/j.numecd.2018.06.013_bib71","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3945\/jn.112.167007","article-title":"Thiamine nutritional status and depressive symptoms are inversely associated among older Chinese adults","volume":"143","author":"Zhang","year":"2013","journal-title":"J Nutr"},{"key":"10.1016\/j.numecd.2018.06.013_bib72","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1192\/bjp.135.3.249","article-title":"Thiamine and pyridoxine lack newly-admitted psychiatric patients","volume":"135","author":"Carney","year":"1979","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.numecd.2018.06.013_bib73","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1749-6632.1982.tb31212.x","article-title":"Effect of thiamin deficiency on brain neurotransmitter systems","volume":"378","author":"Plaitakis","year":"1982","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.numecd.2018.06.013_bib74","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2174\/1566524013363870","article-title":"Molecular mechanisms of thiamine utilization","volume":"1","author":"Singleton","year":"2001","journal-title":"Curr Mol Med"},{"key":"10.1016\/j.numecd.2018.06.013_bib75","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0006-3223(00)00971-9","article-title":"The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death","volume":"48","author":"Sapolsky","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.numecd.2018.06.013_bib76","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/geronj\/46.1.M16","article-title":"Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency","volume":"46","author":"Smidt","year":"1991","journal-title":"J Gerontol"},{"key":"10.1016\/j.numecd.2018.06.013_bib77","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s002130050163","article-title":"Thiamine supplementation mood and cognitive functioning","volume":"129","author":"Benton","year":"1997","journal-title":"Psychopharmacology (Berl)"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475318302011?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475318302011?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T17:34:50Z","timestamp":1720373690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475318302011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":77,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0939475318302011"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2018.06.013","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thiamine deficiency and cardiovascular disorders","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2018.06.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}