{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:11:22Z","timestamp":1785352282612,"version":"3.55.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"the German Federal Ministry of Education and Research (BMBF)","award":["01ZX1306A"],"award-info":[{"award-number":["01ZX1306A"]}]},{"name":"the cluster FoCus","award":["0315540C"],"award-info":[{"award-number":["0315540C"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.numecd.2018.06.022","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T07:25:12Z","timestamp":1530689112000},"page":"1100-1105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases"],"prefix":"10.1016","volume":"28","author":[{"given":"D.M.","family":"Schulte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Paulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"T\u00fcrk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Brandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Freitag-Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Hagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Zeuner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.O.","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Lieb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Nikolaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Mrowietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Gerdes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Laudes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.numecd.2018.06.022_bib1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1136\/annrheumdis-2013-204573","article-title":"EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update","volume":"73","author":"Smolen","year":"2014","journal-title":"Ann Rheum Dis"},{"issue":"12","key":"10.1016\/j.numecd.2018.06.022_bib2","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1002\/1529-0131(200112)44:12<2746::AID-ART461>3.0.CO;2-Z","article-title":"Long-term morbidity, mortality, and economics of rheumatoid arthritis","volume":"44","author":"Wong","year":"2001","journal-title":"Arthritis Rheum"},{"issue":"12","key":"10.1016\/j.numecd.2018.06.022_bib3","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1002\/acr.22091","article-title":"Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population","volume":"65","author":"Liao","year":"2013","journal-title":"Arthritis Care Res"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.022_bib4","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/ard.2010.135871","article-title":"Lipid paradox in rheumatoid arthritis: the impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease","volume":"70","author":"Myasoedova","year":"2011","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"10.1016\/j.numecd.2018.06.022_bib5","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/00041433-199408000-00002","article-title":"Atherosclerosis and arterial influx of lipoproteins","volume":"5","author":"Nordestgaard","year":"1994","journal-title":"Curr Opin Lipidol"},{"issue":"2","key":"10.1016\/j.numecd.2018.06.022_bib6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0002-9343(00)00700-2","article-title":"Enhanced oxidative susceptibility and reduced antioxidant content of metabolic precursors of small, dense low-density lipoproteins","volume":"110","author":"Tribble","year":"2001","journal-title":"Am J Med"},{"issue":"6","key":"10.1016\/j.numecd.2018.06.022_bib7","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1373\/clinchem.2009.137489","article-title":"Small dense LDL cholesterol and coronary heart disease: results from the Framingham offspring study","volume":"56","author":"Ai","year":"2010","journal-title":"Clin Chem"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.022_bib8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/03009742.2012.745013","article-title":"Effects of 12 months of treatment with disease-modifying anti-rheumatic drugs on low and high density lipoprotein subclass distribution in patients with early rheumatoid arthritis: a pilot study","volume":"42","author":"Filippatos","year":"2013","journal-title":"Scand J Rheumatol"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.022_bib9","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1194\/jlr.P052209","article-title":"IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans","volume":"56","author":"M\u00fcller","year":"2015","journal-title":"J Lipid Res"},{"issue":"7\u20138","key":"10.1016\/j.numecd.2018.06.022_bib10","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.cca.2010.12.003","article-title":"Evaluation of a new homogenous method for detection of small dense LDL cholesterol: comparison with the LDL cholesterol profile obtained by density gradient ultracentrifugation","volume":"412","author":"Albers","year":"2011","journal-title":"Clin Chim Acta."},{"issue":"4","key":"10.1016\/j.numecd.2018.06.022_bib11","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1136\/annrheumdis-2013-204345","article-title":"Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study","volume":"74","author":"McInnes","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.numecd.2018.06.022_bib12","series-title":"Endotext. South Dartmouth (MA)","article-title":"The effect of inflammation and infection on lipids and lipoproteins","author":"Feingold","year":"2000"},{"issue":"10","key":"10.1016\/j.numecd.2018.06.022_bib13","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1093\/clinchem\/43.10.1904","article-title":"Measurement of low-density lipoprotein particle size by high-performance gel-filtration chromatography","volume":"43","author":"Scheffer","year":"1997","journal-title":"Clin Chem"},{"key":"10.1016\/j.numecd.2018.06.022_bib14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.atherosclerosis.2009.07.015","article-title":"Atherogenic lipoprotein phenotype and LDL size and subclasses in drug-na\u00efve patients with early rheumatoid arthritis","volume":"207","author":"Rizzo","year":"2009","journal-title":"Atherosklerosis"},{"issue":"3","key":"10.1016\/j.numecd.2018.06.022_bib15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2217\/clp.15.17","article-title":"Biohumoral and comorbidity determinants of low HDL-C during acute phase response in a setting of in-hospital patients","volume":"10","author":"De Vuono","year":"2015","journal-title":"Clin Lipidol"},{"issue":"10","key":"10.1016\/j.numecd.2018.06.022_bib16","doi-asserted-by":"crossref","DOI":"10.1194\/jlr.P076463","article-title":"Plasma cholesterol homeostasis, HDL remodeling and function during the acute phase reaction","volume":"58","author":"Zimetti","year":"2017","journal-title":"J Lipid Res"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.022_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/1529-0131(200001)43:1<14::AID-ANR3>3.0.CO;2-7","article-title":"Response to methotrexate treatment is associated with reduced mortality in patients with severe rheumatoid arthritis","volume":"43","author":"Krause","year":"2000","journal-title":"Arthritis Rheum"},{"issue":"9","key":"10.1016\/j.numecd.2018.06.022_bib18","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.amjcard.2011.06.054","article-title":"Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease","volume":"108","author":"Micha","year":"2011","journal-title":"Am J Cardiol"},{"issue":"5","key":"10.1016\/j.numecd.2018.06.022_bib20","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11926-016-0578-8","article-title":"Rheumatoid arthritis pharmacotherapies: do they have anti-atherosclerotic activity?","volume":"18","author":"Giles","year":"2016","journal-title":"Curr Rheumatol Rep"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.022_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40256-015-0141-4","article-title":"Management of cardiovascular risk in patients with chronic inflammatory diseases: current evidence and future perspectives","volume":"16","author":"Lindhardsen","year":"2016","journal-title":"Am J Cardiovasc Drugs : drugs, devices, and other interventions"},{"issue":"1","key":"10.1016\/j.numecd.2018.06.022_bib22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12891-016-0915-0","article-title":"A prospective, single-centre, randomised study evaluating the clinical, imaging and immunological depth of remission achieved by very early versus delayed Etanercept in patients with Rheumatoid Arthritis (VEDERA)","volume":"17","author":"Dumitru","year":"2016","journal-title":"BMC Muscoskel Disord"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475318302254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475318302254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:08:32Z","timestamp":1760544512000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475318302254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S0939475318302254"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2018.06.022","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2018.06.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V. on behalf of The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University.","name":"copyright","label":"Copyright"}]}}