{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:55:08Z","timestamp":1760576108708,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010438","name":"Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.numecd.2020.11.006","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T01:25:11Z","timestamp":1605230711000},"page":"1219-1226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Suppression of serum lipid transfer proteins involved in high-density lipoprotein cholesterol metabolism by intensive insulin therapy in the first year of type 1 diabetes mellitus: Prospective InLipoDiab1 study"],"prefix":"10.1016","volume":"31","author":[{"given":"Aleksandra","family":"Cieluch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Uruska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Nowicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Wysocka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3359-539X","authenticated-orcid":false,"given":"Agata","family":"Grzelka-Wo\u017aniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justyna","family":"Floty\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawe\u0142","family":"Nied\u017awiecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota","family":"Zozuli\u0144ska-Zi\u00f3\u0142kiewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.numecd.2020.11.006_bib1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.numecd.2019.07.022","article-title":"Antiatherogenic properties of high-density lipoproteins from arterial plasma are attenuated as compared to their counterparts of venous origin","volume":"30","author":"Bonnefont-Rousselot","year":"2020","journal-title":"Nutr Metabol Cardiovasc Dis"},{"key":"10.1016\/j.numecd.2020.11.006_bib2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.jacl.2011.06.011","article-title":"High-density lipoprotein cholesterol in diabetes: is higher always better?","volume":"5","author":"Costacou","year":"2011","journal-title":"J Clin Lipidol"},{"key":"10.1016\/j.numecd.2020.11.006_bib3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0005-2760(78)90147-9","article-title":"The activity of an esterified cholesterol transferring factor in human and rat serum","volume":"531","author":"Barter","year":"1978","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.numecd.2020.11.006_bib4","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.atherosclerosis.2018.09.035","article-title":"Cholesteryl ester transfer protein: an enigmatic pharmacology - antagonists and agonists","volume":"278","author":"Yamashita","year":"2018","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.numecd.2020.11.006_bib5","doi-asserted-by":"crossref","first-page":"338","DOI":"10.2337\/diacare.14.4.338","article-title":"Elevated cholesteryl ester transfer protein activity in IDDM men who smoke. Possible factor for unfavorable lipoprotein profile","volume":"14","author":"Dullaart","year":"1991","journal-title":"Diabetes Care"},{"key":"10.1016\/j.numecd.2020.11.006_bib6","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/j.1651-2227.1999.tb00989.x","article-title":"Decreased activity of plasma cholesteryl ester transfer protein in children and adolescents with insulin-dependent diabetes mellitus","volume":"88","author":"Hayashibe","year":"1999","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.numecd.2020.11.006_bib7","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.2337\/diab.42.9.1281","article-title":"Regulation of apolipoprotein A-I-containing lipoproteins in IDDM","volume":"42","author":"Kahri","year":"1993","journal-title":"Diabetes"},{"key":"10.1016\/j.numecd.2020.11.006_bib8","doi-asserted-by":"crossref","first-page":"526","DOI":"10.3389\/fphys.2018.00526","article-title":"Reverse cholesterol transport: molecular mechanisms and the non-medical approach to enhance HDL cholesterol","volume":"9","author":"Marques","year":"2018","journal-title":"Front Physiol"},{"key":"10.1016\/j.numecd.2020.11.006_bib9","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1056\/NEJM199011013231803","article-title":"Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation","volume":"323","author":"Inazu","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.numecd.2020.11.006_bib10","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1172\/JCI118751","article-title":"Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels","volume":"97","author":"Zhong","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1016\/j.numecd.2020.11.006_bib11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1743-7075-6-49","article-title":"Plasma PLTP activity is inversely associated with HDL-C levels","volume":"6","author":"Chen","year":"2009","journal-title":"Nutr Metab"},{"key":"10.1016\/j.numecd.2020.11.006_bib12","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1161\/01.ATV.20.4.1082","article-title":"Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice","volume":"20","author":"van Haperen","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.numecd.2020.11.006_bib13","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1172\/JCI5578","article-title":"Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels","volume":"103","author":"Jiang","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.numecd.2020.11.006_bib14","doi-asserted-by":"crossref","first-page":"11979","DOI":"10.1021\/bi700833h","article-title":"Cholesterol efflux from macrophage foam cells is enhanced by active phospholipid transfer protein through generation of two types of acceptor particles","volume":"46","author":"Vikstedt","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.numecd.2020.11.006_bib15","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.atherosclerosis.2008.10.020","article-title":"Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice","volume":"204","author":"Samyn","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.numecd.2020.11.006_bib16","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1161\/01.ATV.0000094433.98445.7F","article-title":"High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease","volume":"23","author":"Schlitt","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.numecd.2020.11.006_bib17","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.atherosclerosis.2007.04.046","article-title":"Low phospholipid transfer protein (PLTP) is a risk factor for peripheral atherosclerosis","volume":"196","author":"Schgoer","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.numecd.2020.11.006_bib18","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.2337\/diabetes.51.11.3300","article-title":"Relationship of phospholipid transfer protein activity to HDL and apolipoprotein B-containing lipoproteins in subjects with and without type 1 diabetes","volume":"51","author":"Colhoun","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.numecd.2020.11.006_bib19","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1620\/tjem.213.129","article-title":"Increased phospholipid transfer protein activity associated with the impaired cellular cholesterol efflux in type 2 diabetic subjects with coronary artery disease","volume":"213","author":"Attia","year":"2007","journal-title":"Tohoku J Exp Med"},{"key":"10.1016\/j.numecd.2020.11.006_bib20","first-page":"598","article-title":"Changes in high-density lipoprotein cholesterol (HDL-C) level and the ratio of triglycerides to HDL-C during the first year of type 1 diabetes","volume":"129","author":"Cieluch","year":"2019","journal-title":"Pol Arch Intern Med"},{"key":"10.1016\/j.numecd.2020.11.006_bib21","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1161\/01.CIR.101.16.1907","article-title":"Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene","volume":"101","author":"Agerholm-Larsen","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.numecd.2020.11.006_bib22","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.phrs.2017.12.028","article-title":"Present therapeutic role of cholesteryl ester transfer protein inhibitors","volume":"128","author":"Ferri","year":"2018","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.numecd.2020.11.006_bib23","first-page":"230","article-title":"Plasma lipid transfer proteins and cardiovascular disease","volume":"228","author":"Robins","year":"2013","journal-title":"The Framingham Heart Study. Atherosclerosis."},{"key":"10.1016\/j.numecd.2020.11.006_bib24","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1111\/j.1464-5491.2005.01521.x","article-title":"Human plasma phospholipid transfer protein activity is decreased by acute hyperglycaemia: studies without and with hyperinsulinaemia in Type 1 diabetes mellitus","volume":"22","author":"Oomen","year":"2005","journal-title":"Diabet Med"},{"key":"10.1016\/j.numecd.2020.11.006_bib25","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1139\/y03-093","article-title":"Streptozotocin-induced increase in cholesterol ester transfer protein (CETP) and its reversal by insulin in transgenic mice expressing human CETP","volume":"81","author":"Cheema","year":"2003","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.numecd.2020.11.006_bib26","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1007\/s001250051009","article-title":"Plasma phospholipid transfer protein activity is related to insulin resistance: impaired acute lowering by insulin in obese Type II diabetic patients","volume":"41","author":"Riemens","year":"1998","journal-title":"Diabetologia"},{"key":"10.1016\/j.numecd.2020.11.006_bib27","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.2337\/diabetes.48.8.1631","article-title":"Plasma phospholipid transfer protein activity is lowered by 24-h insulin and acipimox administration: blunted response to insulin in type 2 diabetic patients","volume":"48","author":"Riemens","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.numecd.2020.11.006_bib28","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/0026-0495(94)90028-0","article-title":"The effect of acute hyperinsulinemia on plasma cholesteryl ester transfer protein activity in patients with non-insulin-dependent diabetes mellitus and healthy subjects","volume":"43","author":"Sutherland","year":"1994","journal-title":"Metabolism"},{"key":"10.1016\/j.numecd.2020.11.006_bib29","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/S0026-0495(97)90211-0","article-title":"Suppression of plasma cholesteryl ester transfer protein activity in acute hyperinsulinemia and effect of plasma nonesterified fatty acid","volume":"46","author":"Arii","year":"1997","journal-title":"Metabolism"},{"key":"10.1016\/j.numecd.2020.11.006_bib30","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1476-511X-12-54","article-title":"Effect of insulin analog initiation therapy on LDL\/HDL subfraction profile and HDL associated enzymes in type 2 diabetic patients","volume":"12","author":"Aslan","year":"2013","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.numecd.2020.11.006_bib31","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0953-6205(02)00038-9","article-title":"Insulin improves fasting and postprandial lipemia in type 2 diabetes","volume":"13","author":"Geltner","year":"2002","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.numecd.2020.11.006_bib32","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/j.1749-6632.2001.tb03962.x","article-title":"Increased cholesteryl ester transfer protein and changes in lipid metabolism from initiating insulin therapy","volume":"947","author":"Ai","year":"2001","journal-title":"Ann N Y Acad Sci"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475320304828?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475320304828?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:18:02Z","timestamp":1760545082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475320304828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0939475320304828"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2020.11.006","relation":{},"ISSN":["0939-4753"],"issn-type":[{"type":"print","value":"0939-4753"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Suppression of serum lipid transfer proteins involved in high-density lipoprotein cholesterol metabolism by intensive insulin therapy in the first year of type 1 diabetes mellitus: Prospective InLipoDiab1 study","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2020.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}