{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:45:25Z","timestamp":1791380725478,"version":"4.3.3"},"reference-count":34,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009102","name":"Education Department of Jiangxi Province","doi-asserted-by":"publisher","award":["GJJ170013"],"award-info":[{"award-number":["GJJ170013"]}],"id":[{"id":"10.13039\/501100009102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1312902"],"award-info":[{"award-number":["2018YFC1312902"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012420","name":"5511 Science and Technology Innovation Talent Project of Jiangxi Province","doi-asserted-by":"publisher","award":["20165BCD41005"],"award-info":[{"award-number":["20165BCD41005"]}],"id":[{"id":"10.13039\/501100012420","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81760049"],"award-info":[{"award-number":["81760049"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.numecd.2021.07.002","type":"journal-article","created":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T05:27:28Z","timestamp":1627104448000},"page":"3076-3084","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Positive association between body fat percentage and hyperuricemia in patients with hypertension: The China H-type hypertension registry study"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9668-6745","authenticated-orcid":false,"given":"Yurong","family":"Xiong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wangsheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoshu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.numecd.2021.07.002_bib1","first-page":"235","article-title":"Multi-disciplinary expert task force on hyperuricemia and its related diseases. [Chinese multi-disciplinary consensus on the diagnosis and treatment of hyperuricemia and its related diseases]","volume":"56","year":"2017","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"10.1016\/j.numecd.2021.07.002_bib2","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/art.40807","article-title":"Contemporary prevalence of gout and hyperuricemia in the United States and decadal trends: the national health and nutrition examination survey, 2007-2016","volume":"71","author":"Chen-Xu","year":"2019","journal-title":"ARTHRITIS RHEUMATOL"},{"key":"10.1016\/j.numecd.2021.07.002_bib3","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1161\/HYPERTENSIONAHA.117.10370","article-title":"Uric acid is a strong risk marker for developing hypertension from prehypertension","volume":"71","author":"Kuwabara","year":"2018","journal-title":"Hypertension"},{"key":"10.1016\/j.numecd.2021.07.002_bib4","doi-asserted-by":"crossref","first-page":"19520","DOI":"10.1038\/srep19520","article-title":"Hyperuricemia and the risk for coronary heart disease morbidity and mortality a systematic review and dose-response meta-analysis","volume":"6","author":"Li","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.numecd.2021.07.002_bib5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.archger.2016.01.005","article-title":"Serum uric acid concentration and metabolic syndrome among elderly Koreans: the Korean Urban Rural Elderly (KURE) study","volume":"64","author":"Choi","year":"2016","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.numecd.2021.07.002_bib6","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1136\/annrheumdis-2013-204463","article-title":"Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study","volume":"74","author":"Kuo","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.numecd.2021.07.002_bib7","first-page":"1859","article-title":"Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China","volume":"35","author":"Miao","year":"2008","journal-title":"J Rheumatol"},{"key":"10.1016\/j.numecd.2021.07.002_bib8","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1002\/art.30520","article-title":"Prevalence of gout and hyperuricemia in the US general population: the national health and nutrition examination survey 2007-2008","volume":"63","author":"Zhu","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.numecd.2021.07.002_bib9","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1053\/meta.2001.24196","article-title":"Predictors for development of hyperuricemia: an 8-year longitudinal study in middle-aged Japanese men","volume":"50","author":"Nakanishi","year":"2001","journal-title":"Metabolism"},{"key":"10.1016\/j.numecd.2021.07.002_bib10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/acr.21791","article-title":"Body mass index, obesity, and prevalent gout in the United States in 1988-1994 and 2007-2010","volume":"65","author":"Juraschek","year":"2013","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.numecd.2021.07.002_bib11","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s12199-015-0473-3","article-title":"The relationship between body mass index and uric acid: a study on Japanese adult twins","volume":"20","author":"Tanaka","year":"2015","journal-title":"Environ Health Prev Med"},{"key":"10.1016\/j.numecd.2021.07.002_bib12","first-page":"1503","article-title":"Association of serum uric acid with body mass index: a cross-sectional study from jiangsu Province, China","volume":"43","author":"Wang","year":"2014","journal-title":"Iran J Public Health"},{"key":"10.1016\/j.numecd.2021.07.002_bib13","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1016\/j.jacc.2008.12.068","article-title":"Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss","volume":"53","author":"Lavie","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.numecd.2021.07.002_bib14","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4065\/mcp.2010.0333","article-title":"Body composition and heart failure prevalence and prognosis: getting to the fat of the matter in the \u201cobesity paradox\u201d","volume":"85","author":"Lavie","year":"2010","journal-title":"Mayo Clin Proc"},{"issue":"Suppl 1","key":"10.1016\/j.numecd.2021.07.002_bib15","doi-asserted-by":"crossref","first-page":"S84","DOI":"10.1016\/j.orcp.2016.03.008","article-title":"Metabolically healthy obesity also has risk for hyperuricemia among Chinese general population: a cross-sectional study","volume":"10","author":"Chen","year":"2016","journal-title":"Obes Res Clin Pract"},{"key":"10.1016\/j.numecd.2021.07.002_bib16","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.jacc.2012.05.037","article-title":"Body composition and survival in stable coronary heart disease: impact of lean mass index and body fat in the \u201cobesity paradox\u201d","volume":"60","author":"Lavie","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"36","key":"10.1016\/j.numecd.2021.07.002_bib17","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1097\/HJH.0000000000001940","article-title":"ESC\/ESH Guidelines for the management of arterial hypertension","volume":"2018","author":"Williams","year":"2018","journal-title":"J Hypertens"},{"key":"10.1016\/j.numecd.2021.07.002_bib18","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-020-01124-2","article-title":"Positive association between triglyceride glucose index and arterial stiffness in hypertensive patients: the China H-type Hypertension Registry Study","volume":"19","author":"Li","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2021.07.002_bib19","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2337\/dc11-1334","article-title":"Clinical usefulness of a new equation for estimating body fat","volume":"35","author":"Gomez-Ambrosi","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1016\/j.numecd.2021.07.002_bib20","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-016-0420-7","article-title":"The influence of body composition on renal function in patients with coronary artery disease and its prognostic significance: a retrospective cohort study","volume":"15","author":"Peng","year":"2016","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2021.07.002_bib21","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1161\/01.HYP.0000254480.64564.b6","article-title":"Hyperuricemia and incidence of hypertension among men without metabolic syndrome","volume":"49","author":"Krishnan","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.numecd.2021.07.002_bib22","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1291\/hypres.27.835","article-title":"Hyperuricemia as a predictor of hypertension in a screened cohort in okinawa, Japan","volume":"27","author":"Nagahama","year":"2004","journal-title":"Hypertens Res"},{"key":"10.1016\/j.numecd.2021.07.002_bib23","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.exger.2012.05.008","article-title":"Association of serum uric acid with body mass index among long-lived Chinese","volume":"47","author":"Yue","year":"2012","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.numecd.2021.07.002_bib24","doi-asserted-by":"crossref","first-page":"438","DOI":"10.4158\/EP-2018-0426","article-title":"Association between serum uric acid level and body mass index IN sex- and age-specific groups IN southwestern China","volume":"25","author":"Liu","year":"2019","journal-title":"Endocr Pract"},{"key":"10.1016\/j.numecd.2021.07.002_bib25","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/art.41067","article-title":"Population impact attributable to modifiable risk factors for hyperuricemia","volume":"72","author":"Choi","year":"2020","journal-title":"ARTHRITIS RHEUMATOL"},{"key":"10.1016\/j.numecd.2021.07.002_bib26","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-019-02142-9","article-title":"Nonlinear relationship between serum uric acid and body mass index: a cross-sectional study of a general population in coastal China","volume":"17","author":"Zhou","year":"2019","journal-title":"J Transl Med"},{"key":"10.1016\/j.numecd.2021.07.002_bib27","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-019-2074-1","article-title":"Visceral adipose accumulation increased the risk of hyperuricemia among middle-aged and elderly adults: a population-based study","volume":"17","author":"Huang","year":"2019","journal-title":"J Transl Med"},{"key":"10.1016\/j.numecd.2021.07.002_bib28","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1093\/eurheartj\/ehm243","article-title":"Diagnostic performance of body mass index to detect obesity in patients with coronary artery disease","volume":"28","author":"Romero-Corral","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.numecd.2021.07.002_bib29","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/ijo.2008.11","article-title":"Accuracy of body mass index in diagnosing obesity in the adult general population","volume":"32","author":"Romero-Corral","year":"2008","journal-title":"Int J Obes"},{"key":"10.1016\/j.numecd.2021.07.002_bib30","first-page":"3167","article-title":"Update on the epidemiology, genetics, and therapeutic options of hyperuricemia","volume":"12","author":"Li","year":"2020","journal-title":"AM J TRANSL RES"},{"key":"10.1016\/j.numecd.2021.07.002_bib31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41584-019-0334-3","article-title":"Asymptomatic hyperuricaemia: a silent activator of the innate immune system","volume":"16","author":"Joosten","year":"2020","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.numecd.2021.07.002_bib32","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nrneph.2016.191","article-title":"Kidney disease and obesity: epidemiology, mechanisms and treatment","volume":"13","author":"C\u00e2mara","year":"2017","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.numecd.2021.07.002_bib33","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1681\/ASN.V1261211","article-title":"Functional and structural changes in the kidney in the early stages of obesity","volume":"12","author":"Henegar","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.numecd.2021.07.002_bib34","doi-asserted-by":"crossref","first-page":"27138","DOI":"10.1074\/jbc.M113.485094","article-title":"Uric acid secretion from adipose tissue and its increase in obesity","volume":"288","author":"Tsushima","year":"2013","journal-title":"J Biol Chem"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475321003239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475321003239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:19:13Z","timestamp":1760545153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475321003239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S0939475321003239"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2021.07.002","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Positive association between body fat percentage and hyperuricemia in patients with hypertension: The China H-type hypertension registry study","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2021.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier B.V. on behalf of The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University.","name":"copyright","label":"Copyright"}]}}