{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T22:18:19Z","timestamp":1770329899066,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100273"],"award-info":[{"award-number":["82100273"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002402","name":"Sun Yat-Sen University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2020M673016"],"award-info":[{"award-number":["2020M673016"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012152","name":"National Postdoctoral Program for Innovative Talents","doi-asserted-by":"publisher","award":["BX20200400"],"award-info":[{"award-number":["BX20200400"]}],"id":[{"id":"10.13039\/501100012152","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.numecd.2022.04.020","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T21:30:08Z","timestamp":1651095008000},"page":"1711-1718","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of diabetic retinopathy on prognosis of patients with heart failure with preserved ejection fraction"],"prefix":"10.1016","volume":"32","author":[{"given":"Y.","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ccep.2018.11.001","article-title":"The many faces of heart failure","volume":"11","author":"Snipelisky","year":"2019","journal-title":"Cardiac Electrophysiology Clinics"},{"issue":"9859","key":"10.1016\/j.numecd.2022.04.020_bib2","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/S0140-6736(12)61729-2","article-title":"Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Vos","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.numecd.2022.04.020_bib3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.diabres.2017.03.024","article-title":"IDF Diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040","volume":"128","author":"Ogurtsova","year":"2017","journal-title":"Diabetes Res Clin Pract"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib4","doi-asserted-by":"crossref","DOI":"10.1161\/ATVBAHA.117.310221","article-title":"Highlighting diabetes mellitus","volume":"38","author":"Schmidt","year":"2018","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.numecd.2022.04.020_bib5","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/ejhf.1170","article-title":"Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology","volume":"20","author":"Seferovi\u0107","year":"2018","journal-title":"Eur J Heart Fail"},{"issue":"7","key":"10.1016\/j.numecd.2022.04.020_bib6","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000000691","article-title":"Type 2 diabetes mellitus and heart failure: a scientific statement from the American heart association and the heart failure society of America: this statement does not represent an update of the 2017 ACC\/AHA\/HFSA heart failure guideline update","volume":"140","author":"Dunlay","year":"2019","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.numecd.2022.04.020_bib7","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1007\/s00125-012-2579-0","article-title":"High prevalence of previously unknown heart failure and left ventricular dysfunction in patients with type 2 diabetes","volume":"55","author":"Boonman-de Winter","year":"2012","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.numecd.2022.04.020_bib8","doi-asserted-by":"crossref","DOI":"10.1007\/s11906-017-0709-2","article-title":"Current perspectives on systemic hypertension in heart failure with preserved ejection fraction","volume":"19","author":"Tam","year":"2017","journal-title":"Curr Hypertens Rep"},{"issue":"11","key":"10.1016\/j.numecd.2022.04.020_bib9","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1161\/CIRCRESAHA.119.313572","article-title":"Heart failure with preserved ejection fraction in perspective","volume":"124","author":"Pfeffer","year":"2019","journal-title":"Circ Res"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib10","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1161\/CIRCULATIONAHA.116.021884","article-title":"Phenotype-specific treatment of heart failure with preserved ejection fraction","volume":"134","author":"Shah","year":"2016","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.numecd.2022.04.020_bib11","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1161\/CIRCULATIONAHA.116.025957","article-title":"The diabetic heart failure with preserved ejection fraction phenotype","volume":"135","author":"Lindman","year":"2017","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.numecd.2022.04.020_bib12","first-page":"619","article-title":"Heart failure with preserved ejection fraction expert panel report","volume":"6","author":"Parikh","year":"2018","journal-title":"JACC (J Am Coll Cardiol): Heart Fail"},{"key":"10.1016\/j.numecd.2022.04.020_bib13","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ahj.2016.07.025","article-title":"Temporal trends and factors associated with diabetes mellitus among patients hospitalized with heart failure: findings from Get with the Guidelines\u2013Heart Failure registry","volume":"182","author":"Echouffo-Tcheugui","year":"2016","journal-title":"Am Heart J"},{"issue":"5","key":"10.1016\/j.numecd.2022.04.020_bib14","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.jacc.2018.11.033","article-title":"Heart failure with preserved ejection fraction and diabetes","volume":"73","author":"McHugh","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.numecd.2022.04.020_bib15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0140-6736(09)62124-3","article-title":"Diabetic retinopathy","volume":"376","author":"Cheung","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.numecd.2022.04.020_bib16","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1001\/archopht.122.4.552","article-title":"The prevalence of diabetic retinopathy among adults in the United States","volume":"122","year":"2004","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"10.1016\/j.numecd.2022.04.020_bib17","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/archopht.122.4.546","article-title":"The prevalence of diabetic retinopathy among adult type 1 diabetic persons in the United States","volume":"122","author":"Roy","year":"2004","journal-title":"Arch Ophthalmol (1960)"},{"issue":"39","key":"10.1016\/j.numecd.2022.04.020_bib18","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1093\/eurheartj\/eht108","article-title":"ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD","volume":"34","year":"2013","journal-title":"Eur Heart J"},{"issue":"7","key":"10.1016\/j.numecd.2022.04.020_bib19","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.2337\/dc07-0264","article-title":"Diabetic retinopathy and the risk of coronary heart disease: the atherosclerosis risk in communities study","volume":"30","author":"Cheung","year":"2007","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.numecd.2022.04.020_bib20","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1001\/jamaophthalmol.2017.0988","article-title":"Association of diabetic macular edema and proliferative diabetic retinopathy with cardiovascular disease","volume":"135","author":"Xie","year":"2017","journal-title":"JAMA Ophthalmol"},{"issue":"15","key":"10.1016\/j.numecd.2022.04.020_bib21","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1056\/NEJMoa1313731","article-title":"Spironolactone for heart failure with preserved ejection fraction","volume":"370","author":"Pitt","year":"2014","journal-title":"New Engl J Med"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib22","first-page":"150","article-title":"The prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction. DIABETES CARE","volume":"41","author":"Sandesara","year":"2018","journal-title":"J Article; Multicenter Study; Randomized Controlled Trial"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib23","first-page":"35","article-title":"HFpEF is the substrate for stroke in obesity and diabetes independent of atrial fibrillation","volume":"8","author":"Packer","year":"2020","journal-title":"JACC (J Am Coll Cardiol): Heart Fail"},{"key":"10.1016\/j.numecd.2022.04.020_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2017.00160","article-title":"Targeting obesity and diabetes to treat heart failure with preserved ejection fraction","volume":"8","author":"Altara","year":"2017","journal-title":"Front Endocrinol"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib25","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1161\/CIRCRESAHA.118.311371","article-title":"Heart failure in type 2 diabetes mellitus","volume":"124","author":"Kenny","year":"2019","journal-title":"Circ Res"},{"issue":"12","key":"10.1016\/j.numecd.2022.04.020_bib26","first-page":"1747","article-title":"Early retinal neurovascular impairment in patients with diabetes without clinically detectable retinopathy","volume":"103","author":"Zeng","year":"2019","journal-title":"Br J Ophthalmol. [J Article; Research Support, Non-U.S. Gov't]"},{"key":"10.1016\/j.numecd.2022.04.020_bib27","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1055\/s-0034-1366278","article-title":"Definition, classification and diagnosis of diabetes mellitus","volume":"122","author":"Kerner","year":"2014","journal-title":"Exp Clin Endocrinol Diabetes"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12013-014-9892-9","article-title":"Clinical factors associated with the diagnosis and progression of diabetic nephropathy","volume":"70","author":"Liang","year":"2014","journal-title":"Cell Biochem Biophys"},{"issue":"4","key":"10.1016\/j.numecd.2022.04.020_bib29","first-page":"255","article-title":"Sub-clinical vascular disease in type 2 diabetic subjects: relationship with chronic complications of diabetes and the presence of cardiovascular disease risk factors","volume":"19","author":"Mostaza","year":"2008","journal-title":"Eur J Intern Med. [J Article; Research Support, Non-U.S. Gov't]"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib30","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2174\/1573399812666151012115355","article-title":"Is there any correlation between diabetic retinopathy and risk of cardiovascular disease?","volume":"13","author":"Shoeibi","year":"2017","journal-title":"Curr Diabetes Rev. [J Article]"},{"key":"10.1016\/j.numecd.2022.04.020_bib31","first-page":"11","article-title":"Endothelial dysfunction in diabetic retinopathy","author":"Gui","year":"2020","journal-title":"Front Endocrinol"},{"issue":"4","key":"10.1016\/j.numecd.2022.04.020_bib32","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S0735-1097(97)00242-8","article-title":"Retinopathy identifies marked restriction of coronary flow reserve in patients with diabetes mellitus","volume":"30","author":"Akasaka","year":"1997","journal-title":"J Am Coll Cardiol. [Comparative Study; J Article]"},{"issue":"2","key":"10.1016\/j.numecd.2022.04.020_bib33","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/01.RES.0000052671.53256.49","article-title":"Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles","volume":"92","author":"Miura","year":"2003","journal-title":"Circ Res"},{"issue":"8","key":"10.1016\/j.numecd.2022.04.020_bib34","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1093\/ehjci\/jez266","article-title":"Cardiac perfusion, structure, and function in type 2 diabetes mellitus with and without diabetic complications","volume":"21","author":"S\u00f8rensen","year":"2020","journal-title":"Eur Heart J - Cardiovasc Imaging"},{"issue":"4","key":"10.1016\/j.numecd.2022.04.020_bib35","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1378\/chest.14-2096","article-title":"The impact of associated diabetic retinopathy on stroke and severe bleeding risk in diabetic patients with atrial fibrillation","volume":"147","author":"Lip","year":"2015","journal-title":"Chest"},{"key":"10.1016\/j.numecd.2022.04.020_bib36","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.visres.2017.04.003","article-title":"The pathology associated with diabetic retinopathy","volume":"139","author":"Lechner","year":"2017","journal-title":"Vision Res"},{"issue":"3","key":"10.1016\/j.numecd.2022.04.020_bib37","doi-asserted-by":"crossref","first-page":"498","DOI":"10.2337\/diacare.29.03.06.dc05-1776","article-title":"Cardiovascular risk factors and disease management in type 2 diabetic patients with diabetic nephropathy","volume":"29","author":"Sasso","year":"2006","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib38","doi-asserted-by":"crossref","DOI":"10.1186\/s13098-021-00666-z","article-title":"Proliferative diabetic retinopathy in patients with type 2 diabetes correlates with the presence of atherosclerosis cardiovascular disease","volume":"13","author":"Gao","year":"2021","journal-title":"Diabetol Metab Syndr"},{"issue":"1","key":"10.1016\/j.numecd.2022.04.020_bib39","doi-asserted-by":"crossref","DOI":"10.1186\/s12933-021-01343-1","article-title":"Efficacy and durability of multifactorial intervention on mortality and MACEs: a randomized clinical trial in type-2 diabetic kidney disease","volume":"20","author":"Sasso","year":"2021","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2022.04.020_bib40","first-page":"e3113","article-title":"Applicability of telemedicine in the screening of diabetic retinopathy (DR): the first multicentre study in Italy. The No Blind Study","author":"Sasso","year":"2018","journal-title":"Diabetes\/Metabol Res and Rev"},{"key":"10.1016\/j.numecd.2022.04.020_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/9036847","article-title":"The importance of telemedicine during COVID-19 pandemic: a focus on diabetic retinopathy","volume":"2020","author":"Galiero","year":"2020","journal-title":"J Diabetes Res"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475322001910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475322001910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:21:01Z","timestamp":1760545261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475322001910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":41,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0939475322001910"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2022.04.020","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of diabetic retinopathy on prognosis of patients with heart failure with preserved ejection fraction","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2022.04.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}