{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T15:34:33Z","timestamp":1778254473360,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.numecd.2024.05.014","type":"journal-article","created":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T06:22:27Z","timestamp":1716013347000},"page":"2134-2142","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Long-term burden and increasing trends of body mass index are linked with adult hypertension through triglyceride-glucose index: A 30-year prospective cohort study"],"prefix":"10.1016","volume":"34","author":[{"given":"Yue-Yuan","family":"Liao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-Yue","family":"Man","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0335-3528","authenticated-orcid":false,"given":"Jian-Jun","family":"Mu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.numecd.2024.05.014_bib1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1001\/jamainternmed.2016.0190","article-title":"The burden of hypertension and associated risk for cardiovascular mortality in China","volume":"176","author":"Lewington","year":"2016","journal-title":"JAMA Intern Med"},{"issue":"9455","key":"10.1016\/j.numecd.2024.05.014_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0140-6736(05)17741-1","article-title":"Global burden of hypertension: analysis of worldwide data","volume":"365","author":"Kearney","year":"2005","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.numecd.2024.05.014_bib3","doi-asserted-by":"crossref","first-page":"e211","DOI":"10.1016\/j.orcp.2011.12.005","article-title":"Influence of obesity on blood pressure and arterial stiffness in the early teens","volume":"7","author":"Kudo","year":"2013","journal-title":"Obes Res Clin Pract"},{"issue":"4","key":"10.1016\/j.numecd.2024.05.014_bib4","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jpeds.2011.03.021","article-title":"Tracking of serum lipid levels, blood pressure, and body mass index from childhood to adulthood: the Cardiovascular Risk in Young Finns Study","volume":"159","author":"Juhola","year":"2011","journal-title":"J Pediatr"},{"issue":"3","key":"10.1016\/j.numecd.2024.05.014_bib5","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1093\/ajcn\/76.3.653","article-title":"Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence","volume":"76","author":"Guo","year":"2002","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"10.1016\/j.numecd.2024.05.014_bib6","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1161\/HYPERTENSIONAHA.118.11442","article-title":"Body silhouette trajectories across the lifespan and vascular aging","volume":"72","author":"van Sloten","year":"2018","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.numecd.2024.05.014_bib7","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1089\/met.2008.0034","article-title":"The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects","volume":"6","author":"Simental-Mend\u00eda","year":"2008","journal-title":"Metab Syndr Relat Disord"},{"issue":"7","key":"10.1016\/j.numecd.2024.05.014_bib8","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1210\/jc.2010-0288","article-title":"The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp","volume":"95","author":"Guerrero-Romero","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.numecd.2024.05.014_bib9","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s40292-020-00408-8","article-title":"Insulin resistance the hinge between hypertension and type 2 diabetes","volume":"27","author":"Mancusi","year":"2020","journal-title":"High Blood Pres Cardiovasc Prev"},{"issue":"1","key":"10.1016\/j.numecd.2024.05.014_bib10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1758-5996-6-12","article-title":"Link between insulin resistance and hypertension: what is the evidence from evolutionary biology?","volume":"6","author":"Zhou","year":"2014","journal-title":"Diabetol Metab Syndrome"},{"issue":"10","key":"10.1016\/j.numecd.2024.05.014_bib11","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1210\/jc.2011-1182","article-title":"Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies","volume":"96","author":"Khan","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.numecd.2024.05.014_bib12","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1210\/rp.59.1.207","article-title":"Obesity, insulin resistance, and cardiovascular disease","volume":"59","author":"Reaven","year":"2004","journal-title":"Recent Prog Horm Res"},{"issue":"12","key":"10.1016\/j.numecd.2024.05.014_bib13","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1681\/ASN.2018030263","article-title":"Association of blood pressure trajectories in early life with subclinical renal damage in middle age","volume":"29","author":"Zheng","year":"2018","journal-title":"J Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.numecd.2024.05.014_bib14","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.numecd.2020.09.009","article-title":"Long-term burden of higher body mass index from childhood on adult cardiometabolic biomarkers: a 30-year cohort study","volume":"31","author":"Liao","year":"2021","journal-title":"Nutr Metabol Cardiovasc Dis"},{"issue":"10","key":"10.1016\/j.numecd.2024.05.014_bib15","doi-asserted-by":"crossref","first-page":"769","DOI":"10.2471\/BLT.09.064709","article-title":"Trends in smoking and quitting in China from 1993 to 2003: national health service survey data","volume":"88","author":"Qian","year":"2010","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.numecd.2024.05.014_bib16","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.puhe.2018.01.003","article-title":"Effects of smoking and alcohol consumption on lipid profile in male adults in northwest rural China","volume":"157","author":"Li","year":"2018","journal-title":"Publ Health"},{"key":"10.1016\/j.numecd.2024.05.014_bib17","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.atherosclerosis.2020.10.003","article-title":"Sex differences in impact of long-term burden and trends of body mass index and blood pressure from childhood to adulthood on arterial stiffness in adults: a 30-year cohort study","volume":"313","author":"Liao","year":"2020","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.numecd.2024.05.014_bib18","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1097\/HJH.0000000000002020","article-title":"Predictors for progressions of brachial-ankle pulse wave velocity and carotid intima-media thickness over a 12-year follow-up: Hanzhong Adolescent Hypertension Study","volume":"37","author":"Wang","year":"2019","journal-title":"J Hypertens"},{"issue":"5","key":"10.1016\/j.numecd.2024.05.014_bib19","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1161\/01.HYP.0000161881.02361.11","article-title":"Autosomal genome scan for loci linked to blood pressure levels and trends since childhood: the Bogalusa Heart Study","volume":"45","author":"Chen","year":"2005","journal-title":"Hypertension"},{"issue":"15","key":"10.1016\/j.numecd.2024.05.014_bib20","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1016\/j.jacc.2014.05.072","article-title":"Impact of long-term burden of excessive adiposity and elevated blood pressure from childhood on adulthood left ventricular remodeling patterns: the Bogalusa Heart Study","volume":"64","author":"Lai","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.numecd.2024.05.014_bib21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1146\/annurev-publhealth-032315-021402","article-title":"Mediation analysis: a practitioner's guide","volume":"37","author":"VanderWeele","year":"2016","journal-title":"Annu Rev Publ Health"},{"issue":"10","key":"10.1016\/j.numecd.2024.05.014_bib22","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1161\/CIRCRESAHA.116.310421","article-title":"Long-term excessive body weight and adult left ventricular hypertrophy are linked through later-life body size and blood pressure: the bogalusa heart study","volume":"120","author":"Zhang","year":"2017","journal-title":"Circ Res"},{"issue":"13","key":"10.1016\/j.numecd.2024.05.014_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v059.i13","article-title":"structSSI: simultaneous and selective inference for grouped or hierarchically structured data","volume":"59","author":"Sankaran","year":"2014","journal-title":"J Stat Software"},{"issue":"6","key":"10.1016\/j.numecd.2024.05.014_bib24","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1161\/CIRCRESAHA.116.305697","article-title":"Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms","volume":"116","author":"Hall","year":"2015","journal-title":"Circ Res"},{"issue":"8","key":"10.1016\/j.numecd.2024.05.014_bib25","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1001\/jama.2014.732","article-title":"Prevalence of childhood and adult obesity in the United States, 2011-2012","volume":"311","author":"Ogden","year":"2014","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.numecd.2024.05.014_bib26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.annepidem.2007.07.090","article-title":"Path analysis of metabolic syndrome components in black versus white children, adolescents, and adults: the Bogalusa Heart Study","volume":"18","author":"Chen","year":"2008","journal-title":"Ann Epidemiol"},{"issue":"25","key":"10.1016\/j.numecd.2024.05.014_bib27","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1056\/NEJMoa1503840","article-title":"Body-mass index in 2.3 million adolescents and cardiovascular death in adulthood","volume":"374","author":"Twig","year":"2016","journal-title":"N Engl J Med"},{"issue":"20","key":"10.1016\/j.numecd.2024.05.014_bib28","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1056\/NEJMoa1010112","article-title":"Childhood adiposity, adult adiposity, and cardiovascular risk factors","volume":"365","author":"Juonala","year":"2011","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.numecd.2024.05.014_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/jch.14405","article-title":"Mediation effect of obesity on the association between triglyceride-glucose index and hyperuricemia in Chinese hypertension adults","volume":"24","author":"Sun","year":"2022","journal-title":"J Clin Hypertens"},{"key":"10.1016\/j.numecd.2024.05.014_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.phrs.2017.05.013","article-title":"Obesity and hypertension","volume":"122","author":"Seravalle","year":"2017","journal-title":"Pharmacol Res"},{"issue":"4","key":"10.1016\/j.numecd.2024.05.014_bib31","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1111\/jdi.12975","article-title":"Fasting triglycerides and glucose index is more suitable for the identification of metabolically unhealthy individuals in the Chinese adult population: a nationwide study","volume":"10","author":"Yu","year":"2019","journal-title":"J Diabetes Investig"},{"key":"10.1016\/j.numecd.2024.05.014_bib32","article-title":"Associations of triglyceride-glucose index and its derivatives with hyperuricemia risk: a cohort study in Chinese general population","volume":"2020","author":"Gu","year":"2020","journal-title":"Internet J Endocrinol"},{"key":"10.1016\/j.numecd.2024.05.014_bib33","article-title":"Association between triglyceride-glucose index and hypertension: a meta-analysis","volume":"8","author":"Wang","year":"2021","journal-title":"Front Cardiovasc Med"},{"issue":"1","key":"10.1016\/j.numecd.2024.05.014_bib34","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12933-020-01077-6","article-title":"A high triglyceride glucose index is more closely associated with hypertension than lipid or glycemic parameters in elderly individuals: a cross-sectional survey from the Reaction Study","volume":"19","author":"Zhu","year":"2020","journal-title":"Cardiovasc Diabetol"},{"issue":"19","key":"10.1016\/j.numecd.2024.05.014_bib35","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1001\/archinte.164.19.2126","article-title":"The prevalence of prehypertension and hypertension among US adults according to the new joint national committee guidelines: new challenges of the old problem","volume":"164","author":"Wang","year":"2004","journal-title":"Arch Intern Med"},{"issue":"3","key":"10.1016\/j.numecd.2024.05.014_bib36","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.2612","article-title":"The triglyceride-glucose index and obesity-related risk of end-stage kidney disease in Austrian adults","volume":"4","author":"Fritz","year":"2021","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.numecd.2024.05.014_bib37","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12933-021-01305-7","article-title":"Change in triglyceride-glucose index predicts the risk of cardiovascular disease in the general population: a prospective cohort study","volume":"20","author":"Wang","year":"2021","journal-title":"Cardiovasc Diabetol"},{"issue":"2","key":"10.1016\/j.numecd.2024.05.014_bib38","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s12020-021-02862-3","article-title":"Triglyceride-glucose index associated with the risk of cardiovascular disease: the Kailuan study","volume":"75","author":"Liu","year":"2022","journal-title":"Endocrine"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324001996?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324001996?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T14:57:32Z","timestamp":1728399452000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475324001996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S0939475324001996"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2024.05.014","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term burden and increasing trends of body mass index are linked with adult hypertension through triglyceride-glucose index: A 30-year prospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2024.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V. on behalf of The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University.","name":"copyright","label":"Copyright"}]}}