{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T13:48:11Z","timestamp":1781272091218,"version":"3.54.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.numecd.2024.09.009","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T10:35:12Z","timestamp":1726137312000},"page":"2757-2762","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Uric acid reference values for children and adolescents should be stratified by pubertal stage"],"prefix":"10.1016","volume":"34","author":[{"given":"Shurong","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qifa","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoguang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongfei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiru","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingfan","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4101-8429","authenticated-orcid":false,"given":"Zhe","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.numecd.2024.09.009_bib1","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1080\/07853890.2022.2083670","article-title":"Prevalence and related factors of hyperuricaemia in Chinese children and adolescents: a pooled analysis of 11 population-based studies","volume":"54","author":"Rao","year":"2022","journal-title":"Ann Med"},{"key":"10.1016\/j.numecd.2024.09.009_bib2","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.jped.2023.05.001","article-title":"Analysis of the prevalence and influencing factors of hyperuricemia in children and adolescents aged 6-17 years in northeastern Sichuan Province","volume":"99","author":"Guo","year":"2023","journal-title":"J Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.791983","article-title":"Prevalence of hyperuricemia among Chinese adults: findings from two nationally representative cross-sectional surveys in 2015-16 and 2018-19","volume":"12","author":"Zhang","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.numecd.2024.09.009_bib4","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1007\/s00431-023-04904-6","article-title":"Trends in serum uric acid levels among Korean children and adolescents between 2016 and 2020: a nationwide study","volume":"182","author":"Kim","year":"2023","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib5","first-page":"913","article-title":"Chinese expert consensus on hyperuricemia and gout treament","volume":"29","author":"Association","year":"2013","journal-title":"Chin J eNdocrinol Metab"},{"key":"10.1016\/j.numecd.2024.09.009_bib6","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/BOR.0000000000000028","article-title":"Definition of hyperuricemia and gouty conditions","volume":"26","author":"Bardin","year":"2014","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.numecd.2024.09.009_bib7","first-page":"1287","article-title":"Strategy of diagnosis and treatment of hypeuricemia in children with chronic kidney disease","volume":"34","author":"Xia","year":"2019","journal-title":"Chin J Appl Clin Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.numecd.2019.08.019","article-title":"Influence of muscle mass on the serum uric acid levels in children and adolescents","volume":"30","author":"Alvim","year":"2020","journal-title":"Nutr Metabol Cardiovasc Dis"},{"key":"10.1016\/j.numecd.2024.09.009_bib9","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1038\/s41390-020-01185-9","article-title":"Uric acid reference values: report on 1750 healthy Brazilian children and adolescents","volume":"89","author":"Moulin-Mares","year":"2021","journal-title":"Pediatr Res"},{"key":"10.1016\/j.numecd.2024.09.009_bib10","article-title":"Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys","volume":"11","author":"Wang","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.numecd.2024.09.009_bib11","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.3390\/jcm11102743","article-title":"The association between serum testosterone and hyperuricemia in males","volume":"11","author":"Tsai","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.numecd.2024.09.009_bib12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.2147\/DMSO.S448638","article-title":"A gender-, age-, and weight status-specific analysis of the high prevalence of hyperuricemia among Chinese children and adolescents with obesity","volume":"17","author":"Liu","year":"2024","journal-title":"Diabet Metabol Syndrome Obesity"},{"key":"10.1016\/j.numecd.2024.09.009_bib13","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.numecd.2020.09.012","article-title":"Association of uric acid with cardiovascular risk in Brazilian children and adolescents","volume":"31","author":"Moulin-Mares","year":"2021","journal-title":"Nutr Metabol Cardiovasc Dis"},{"key":"10.1016\/j.numecd.2024.09.009_bib14","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3389\/fendo.2019.00230","article-title":"Obesity-related genetic variants and hyperuricemia risk in Chinese men","volume":"10","author":"Ma","year":"2019","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.numecd.2024.09.009_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.737573","article-title":"Hyperuricemia in psoriatic arthritis: epidemiology, pathophysiology, and clinical implications","volume":"8","author":"Tripolino","year":"2021","journal-title":"Front Med"},{"key":"10.1016\/j.numecd.2024.09.009_bib16","first-page":"2749","article-title":"Roles of hyperuricemia in metabolic syndrome and cardiac-kidney-vascular system diseases","volume":"10","author":"Wang","year":"2018","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.numecd.2024.09.009_bib17","first-page":"S22","article-title":"Serum uric acid and hyperuricemia in U.S. adolescents: 40-year trends","volume":"34","author":"Kumar","year":"2016","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.numecd.2024.09.009_bib18","article-title":"Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies","volume":"357","author":"Li","year":"2017","journal-title":"BMJ"},{"key":"10.1016\/j.numecd.2024.09.009_bib19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3345\/kjp.2019.00444","article-title":"Prevalence of hyperuricemia and its association with metabolic syndrome and cardiometabolic risk factors in Korean children and adolescents: analysis based on the 2016-2017 Korea National Health and Nutrition Examination Survey","volume":"62","author":"Lee","year":"2019","journal-title":"Korean J Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib20","article-title":"Abnormal bone turnover observed in obese children based on puberty stage -specific bone turnover marker reference","volume":"1","author":"Wu","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.numecd.2024.09.009_bib21","first-page":"487","article-title":"Body mass index growth curves for Chinese children and adolescents aged 0 to 18 years","volume":"47","author":"Li","year":"2009","journal-title":"Chinese Journal of Pediatrics"},{"key":"10.1016\/j.numecd.2024.09.009_bib22","first-page":"428","article-title":"Updating blood pressure references for Chinese children aged 3-17years","volume":"25","author":"Hui","year":"2017","journal-title":"Chin J Hypertens"},{"key":"10.1016\/j.numecd.2024.09.009_bib23","first-page":"315","article-title":"Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)","volume":"13","author":"Society","year":"2021","journal-title":"Chin J Diabetes Mellitus"},{"key":"10.1016\/j.numecd.2024.09.009_bib24","first-page":"633","volume":"60","year":"2022","journal-title":"Chin J Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.560720","article-title":"Age and gender-specific reference intervals for uric acid level in children aged 5-14 Years in southeast zhejiang province of China: hyperuricemia in children may need redefinition","volume":"9","author":"Dai","year":"2021","journal-title":"Front Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib26","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jpeds.2012.06.008","article-title":"Hyperuricemia is associated with hypertension, obesity, and albuminuria in children with chronic kidney disease","volume":"162","author":"Noone","year":"2013","journal-title":"J Pediatr-Us"},{"key":"10.1016\/j.numecd.2024.09.009_bib27","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1620\/tjem.209.257","article-title":"Serum uric acid as an obesity-related indicator in early adolescence","volume":"209","author":"Oyama","year":"2006","journal-title":"Tohoku J Exp Med"},{"key":"10.1016\/j.numecd.2024.09.009_bib28","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1007\/s12519-022-00573-x","article-title":"Associations between body mass index in different childhood age periods and hyperuricemia in young adulthood: the China Health and Nutrition Survey cohort study","volume":"18","author":"Qian","year":"2022","journal-title":"World J Pediatr"},{"key":"10.1016\/j.numecd.2024.09.009_bib29","first-page":"E1172","article-title":"Testosterone dose-response relationships in healthy young men","volume":"281","author":"Bhasin","year":"2001","journal-title":"Am J Physiol-Endoc M"},{"key":"10.1016\/j.numecd.2024.09.009_bib30","article-title":"Skeletal muscle mass has stronger association with the risk of hyperuricemia than body fat mass in obese children and adolescents","volume":"9","author":"Xie","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.numecd.2024.09.009_bib31","doi-asserted-by":"crossref","DOI":"10.1007\/s11906-017-0770-x","article-title":"Hyperuricemia, type 2 diabetes mellitus, and hypertension: an emerging association","volume":"19","author":"Mortada","year":"2017","journal-title":"Curr Hypertens Rep"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324003582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324003582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T20:38:06Z","timestamp":1737319086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475324003582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0939475324003582"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2024.09.009","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uric acid reference values for children and adolescents should be stratified by pubertal stage","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2024.09.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}