{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T18:10:36Z","timestamp":1783534236034,"version":"3.55.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"am","delay-in-days":363,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100008868","name":"Jiangsu Province Department of Science and Technology","doi-asserted-by":"publisher","award":["BE2022708"],"award-info":[{"award-number":["BE2022708"]}],"id":[{"id":"10.13039\/501100008868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.numecd.2024.103788","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T01:34:02Z","timestamp":1731029642000},"page":"103788","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Abdominal obesity: A lethal factor in elderly male osteoporosis patients \u2013 insights from NHANES"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0312-4744","authenticated-orcid":false,"given":"Ziyao","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzhe","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qirui","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengya","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changchang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuchao","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maji","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6580-2995","authenticated-orcid":false,"given":"Feng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.numecd.2024.103788_bib1","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650090802","article-title":"The diagnosis of osteoporosis","volume":"9","author":"Kanis","year":"1994","journal-title":"J Bone Miner Res : the official journal of the American Society for Bone and Mineral Research"},{"key":"10.1016\/j.numecd.2024.103788_bib2","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00198-013-2523-2","article-title":"Too Fit to Fracture: exercise recommendations for individuals with osteoporosis or osteoporotic vertebral fracture","volume":"25","author":"Giangregorio","year":"2014","journal-title":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.numecd.2024.103788_bib3","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1007\/s00198-021-05900-y","article-title":"The clinician's guide to prevention and treatment of osteoporosis","volume":"33","author":"LeBoff","year":"2022","journal-title":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.numecd.2024.103788_bib4","doi-asserted-by":"crossref","first-page":"8303","DOI":"10.3390\/ijms23158303","article-title":"Obesity and bone health: a complex relationship","volume":"23","author":"Pi\u00f1ar-Gutierrez","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.numecd.2024.103788_bib5","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1016\/j.clnu.2023.10.013","article-title":"The effect of overweight or obesity on osteoporosis: a systematic review and meta-analysis","volume":"42","author":"Liu","year":"2023","journal-title":"Clinical Nutrition"},{"key":"10.1016\/j.numecd.2024.103788_bib6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejim.2017.10.020","article-title":"Obesity phenotypes and their paradoxical association with cardiovascular diseases","volume":"48","author":"Vecchi\u00e9","year":"2018","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.numecd.2024.103788_bib7","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1056\/NEJMoa0801891","article-title":"General and abdominal adiposity and risk of death in Europe","volume":"359","author":"Pischon","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.numecd.2024.103788_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph182111607","article-title":"Effectiveness of Body Roundness Index (BRI) and a Body Shape Index (ABSI) in predicting hypertension: a systematic review and meta-analysis of observational studies","volume":"18","author":"Calder\u00f3n-Garc\u00eda","year":"2021","journal-title":"Int J Environ Res Publ Health"},{"key":"10.1016\/j.numecd.2024.103788_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0039504","article-title":"A new body shape index predicts mortality hazard independently of body mass index","volume":"7","author":"Krakauer","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.numecd.2024.103788_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.839074","article-title":"Association of sarcopenia and A body shape index with overall and cause-specific mortality","volume":"13","author":"Qiao","year":"2022","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.numecd.2024.103788_bib11","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1007\/s10654-018-0433-5","article-title":"Comparison of the association of predicted fat mass, body mass index, and other obesity indicators with type 2 diabetes risk: two large prospective studies in US men and women","volume":"33","author":"Lee","year":"2018","journal-title":"European journal of epidemiology"},{"key":"10.1016\/j.numecd.2024.103788_bib12","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.numecd.2022.11.018","article-title":"Sex-and age-specific differences in associations of a body shape index with all-cause and cardiovascular death risks among US adults with diabetes","volume":"33","author":"Sun","year":"2023","journal-title":"Nutr Metabol Cardiovasc Dis"},{"key":"10.1016\/j.numecd.2024.103788_bib13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1186\/s12933-023-02030-z","article-title":"The triglyceride-glucose index is a predictor for cardiovascular and all-cause mortality in CVD patients with diabetes or pre-diabetes: evidence from NHANES 2001-2018","volume":"22","author":"Zhang","year":"2023","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2024.103788_bib14","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.46124","article-title":"Associations of serum folate and vitamin B12 levels with cardiovascular disease mortality among patients with type 2 diabetes","volume":"5","author":"Liu","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.numecd.2024.103788_bib15","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s12933-023-01986-2","article-title":"Association of cardio-renal biomarkers and mortality in the U.S.: a prospective cohort study","volume":"22","author":"Yang","year":"2023","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2024.103788_bib16","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1007\/s00198-013-2413-7","article-title":"Standardising the descriptive epidemiology of osteoporosis: recommendations from the epidemiology and quality of life working group of IOF","volume":"24","author":"Kanis","year":"2013","journal-title":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.numecd.2024.103788_bib17","first-page":"357","article-title":"Bone mineral density among men and women aged 35 to 50 years","volume":"119","author":"Bass","year":"2019","journal-title":"The Journal of the American Osteopathic Association"},{"key":"10.1016\/j.numecd.2024.103788_bib18","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s001980050093","article-title":"Updated data on proximal femur bone mineral levels of US adults","volume":"8","author":"Looker","year":"1998","journal-title":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.numecd.2024.103788_bib19","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1186\/s12933-023-02038-5","article-title":"Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study","volume":"22","author":"Tan","year":"2023","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2024.103788_bib20","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12944-022-01721-y","article-title":"Distribution of lipid levels and prevalence of hyperlipidemia: data from the NHANES 2007-2018","volume":"21","author":"Li","year":"2022","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.numecd.2024.103788_bib21","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2337\/dc22-1339","article-title":"Association of serum uric acid with all-cause and cardiovascular mortality in diabetes","volume":"46","author":"Li","year":"2023","journal-title":"Diabetes Care"},{"key":"10.1016\/j.numecd.2024.103788_bib22","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1186\/s12933-023-01998-y","article-title":"The neutrophil-lymphocyte ratio as a risk factor for all-cause and cardiovascular mortality among individuals with diabetes: evidence from the NHANES 2003-2016","volume":"22","author":"Dong","year":"2023","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.numecd.2024.103788_bib23","series-title":"Biomolecules & biomedicine","article-title":"Development and evaluation of interpretable machine learning regressors for predicting femoral neck bone mineral density in elderly men using NHANES data","author":"He","year":"2024"},{"key":"10.1016\/j.numecd.2024.103788_bib24","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1007\/s40520-021-01817-y","article-title":"Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people","volume":"33","author":"Barnsley","year":"2021","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.numecd.2024.103788_bib25","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1210\/endrev\/bnab028","article-title":"Secondary osteoporosis","volume":"43","author":"Ebeling","year":"2022","journal-title":"Endocr Rev"},{"key":"10.1016\/j.numecd.2024.103788_bib26","doi-asserted-by":"crossref","first-page":"801","DOI":"10.7326\/M18-0950","article-title":"How would you manage this patient with osteoporosis?: grand rounds discussion from beth Israel deaconess medical center","volume":"168","author":"Burns","year":"2018","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.numecd.2024.103788_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115597","article-title":"Bone mineral density and osteoporosis in relation to all-cause and cause-specific mortality in NHANES: a population-based cohort study","volume":"141","author":"Cai","year":"2020","journal-title":"Bone"},{"key":"10.1016\/j.numecd.2024.103788_bib28","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12944-018-0856-8","article-title":"Localization of fat depots and cardiovascular risk","volume":"17","author":"Gruzdeva","year":"2018","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.numecd.2024.103788_bib29","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1161\/CIRCRESAHA.121.318093","article-title":"Obesity, adipose tissue and vascular dysfunction","volume":"128","author":"Koenen","year":"2021","journal-title":"Circ Res"},{"key":"10.1016\/j.numecd.2024.103788_bib30","doi-asserted-by":"crossref","DOI":"10.2337\/dcS13-2023","article-title":"Obesity paradox does exist","volume":"36","author":"Hainer","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.numecd.2024.103788_bib31","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1186\/s13018-022-03161-x","article-title":"Association between obesity and bone mineral density in middle-aged adults","volume":"17","author":"Li","year":"2022","journal-title":"J Orthop Surg Res"},{"key":"10.1016\/j.numecd.2024.103788_bib32","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s13018-023-03654-3","article-title":"The association between abdominal obesity and femoral neck bone mineral density in older adults","volume":"18","author":"Chen","year":"2023","journal-title":"J Orthop Surg Res"},{"key":"10.1016\/j.numecd.2024.103788_bib33","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s11657-024-01424-0","article-title":"Association of a body shape index with femur bone mineral density among older adults: NHANES 2007\u20132018","volume":"19","author":"Zhang","year":"2024","journal-title":"Arch Osteoporosis"},{"key":"10.1016\/j.numecd.2024.103788_bib34","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.cmet.2018.12.007","article-title":"Exercise-induced changes in visceral adipose tissue mass are regulated by IL-6 signaling: a randomized controlled trial","volume":"29","author":"Wedell-Neergaard","year":"2019","journal-title":"Cell Metabol"},{"key":"10.1016\/j.numecd.2024.103788_bib35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12020-015-0554-5","article-title":"Preservation of high-fat diet-induced femoral trabecular bone loss through genetic target of TNF-\u03b1","volume":"50","author":"Zhang","year":"2015","journal-title":"Endocrine"},{"key":"10.1016\/j.numecd.2024.103788_bib36","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.3390\/ijms24054831","article-title":"Are the properties of bone marrow-derived mesenchymal stem cells influenced by overweight and obesity?","volume":"24","author":"Zong","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.numecd.2024.103788_bib37","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nature10763","article-title":"The contribution of bone to whole-organism physiology","volume":"481","author":"Karsenty","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.numecd.2024.103788_bib38","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1359\/jbmr.2002.17.10.1896","article-title":"Relationship of serum leptin concentration with bone mineral density in the United States population","volume":"17","author":"Ruhl","year":"2002","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.numecd.2024.103788_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.868166","article-title":"Impact of the malnutrition on mortality in patients with osteoporosis: a cohort study from NHANES 2005-2010","volume":"9","author":"Shangguan","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.numecd.2024.103788_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0177779","article-title":"Body shape index: sex-specific differences in predictive power for all-cause mortality in the Japanese population","volume":"12","author":"Sato","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.numecd.2024.103788_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.xgen.2023.100362","article-title":"Large-scale exome sequence analysis identifies sex-and age-specific determinants of obesity","volume":"3","author":"Kaisinger","year":"2023","journal-title":"Cell genomics"},{"key":"10.1016\/j.numecd.2024.103788_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12902-018-0232-8","article-title":"Association of thyroid nodules with adiposity: a community-based cross-sectional study in China","volume":"18","author":"Song","year":"2018","journal-title":"BMC Endocr Disord"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324004228?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475324004228?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:37:11Z","timestamp":1762331831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475324004228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S0939475324004228"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2024.103788","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Abdominal obesity: A lethal factor in elderly male osteoporosis patients \u2013 insights from NHANES","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2024.103788","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103788"}}