{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:51:17Z","timestamp":1788954677218,"version":"build-2803163510"},"reference-count":29,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100008081","name":"Southeast University","doi-asserted-by":"publisher","award":["2023zxyxt01"],"award-info":[{"award-number":["2023zxyxt01"]}],"id":[{"id":"10.13039\/501100008081","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.numecd.2025.103852","type":"journal-article","created":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T21:24:37Z","timestamp":1736025877000},"page":"103852","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association of remnant cholesterol with coronary heart disease and severity of coronary artery stenosis in non-dialysis patients with stage 3\u20135 chronic kidney disease"],"prefix":"10.1016","volume":"35","author":[{"given":"Xiyue","family":"Mei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0170-5247","authenticated-orcid":false,"given":"Ruizhao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuolin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengchun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rining","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3522-930X","authenticated-orcid":false,"given":"Hong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.numecd.2025.103852_bib1","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.kint.2019.07.012","article-title":"A single number for advocacy and communication\u2014worldwide more than 850 million individuals have kidney diseases","volume":"96","author":"Jager","year":"2019","journal-title":"Kidney Int"},{"issue":"10225","key":"10.1016\/j.numecd.2025.103852_bib2","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"395","year":"2020","journal-title":"Lancet Lond Engl"},{"issue":"1","key":"10.1016\/j.numecd.2025.103852_bib3","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/sj.ki.5002273","article-title":"Chronic kidney disease management in the United Kingdom: NEOERICA project results","volume":"72","author":"Stevens","year":"2007","journal-title":"Kidney Int"},{"issue":"10","key":"10.1016\/j.numecd.2025.103852_bib4","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1681\/ASN.2014070714","article-title":"Cause of death in patients with reduced kidney function","volume":"26","author":"Thompson","year":"2015","journal-title":"J Am Soc Nephrol JASN"},{"issue":"42","key":"10.1016\/j.numecd.2025.103852_bib5","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1093\/eurheartj\/ehw334","article-title":"Cardiovascular disease in Europe: epidemiological update 2016","volume":"37","author":"Townsend","year":"2016","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.numecd.2025.103852_bib6","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.3390\/ijms24054268","article-title":"Cholesterol remnants, triglyceride-rich lipoproteins and cardiovascular risk","volume":"24","author":"Baratta","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"9","key":"10.1016\/j.numecd.2025.103852_bib7","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.3390\/nu15092202","article-title":"Measurement of serum low density lipoprotein cholesterol and triglyceride-rich remnant cholesterol as independent Predictors of atherosclerotic cardiovascular disease: Possibilities and limitations","volume":"15","author":"L\u00fctjohann","year":"2023","journal-title":"Nutrients"},{"issue":"10","key":"10.1016\/j.numecd.2025.103852_bib8","article-title":"Remnant cholesterol, coronary atheroma progression and clinical events in statin-treated patients with coronary artery disease","volume":"27","author":"Mb","year":"2020","journal-title":"Eur J Prev Cardiol"},{"issue":"39","key":"10.1016\/j.numecd.2025.103852_bib9","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1093\/eurheartj\/ehad337","article-title":"Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study","volume":"44","author":"Bj\u00f6rnson","year":"2023","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.numecd.2025.103852_bib10","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.002765","article-title":"Remnant lipoprotein cholesterol and incident coronary heart disease: the Jackson heart and Framingham Offspring cohort studies","volume":"5","author":"Joshi","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.numecd.2025.103852_bib11","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.atherosclerosis.2019.08.014","article-title":"ESC\/EAS guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk","volume":"290","year":"2019","journal-title":"Atherosclerosis"},{"issue":"9","key":"10.1016\/j.numecd.2025.103852_bib12","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.numecd.2025.103852_bib13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.atherosclerosis.2019.05.012","article-title":"A guide for Gensini Score calculation","volume":"287","author":"Rampidis","year":"2019","journal-title":"Atherosclerosis"},{"issue":"8","key":"10.1016\/j.numecd.2025.103852_bib14","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/s41581-022-00576-x","article-title":"Cardiac metabolic remodelling in chronic kidney disease","volume":"18","author":"Patel","year":"2022","journal-title":"Nat Rev Nephrol"},{"issue":"3","key":"10.1016\/j.numecd.2025.103852_bib15","first-page":"353","article-title":"Dyslipidemia in patients with kidney disease","volume":"39","author":"Thobani","year":"2021","journal-title":"Cardiol Clin"},{"issue":"5","key":"10.1016\/j.numecd.2025.103852_bib16","doi-asserted-by":"crossref","first-page":"2658","DOI":"10.3390\/ijms25052658","article-title":"Novel Perspectives in chronic kidney disease-specific cardiovascular disease","volume":"25","author":"Xu","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"11","key":"10.1016\/j.numecd.2025.103852_bib17","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1093\/eurheartj\/ehr112","article-title":"Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management","volume":"32","author":"Chapman","year":"2011","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.numecd.2025.103852_bib18","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1210\/er.2018-00184","article-title":"The Forgotten lipids: triglycerides, remnant cholesterol, and atherosclerotic cardiovascular disease risk","volume":"40","author":"Sandesara","year":"2019","journal-title":"Endocr Rev"},{"issue":"2","key":"10.1016\/j.numecd.2025.103852_bib19","first-page":"61","article-title":"Triglyceride-rich lipoproteins: their role in atherosclerosis","volume":"74","author":"Castillo-N\u00fa\u00f1ez","year":"2022","journal-title":"Rev Investig Clin Organo Hosp Enfermedades Nutr"},{"issue":"21","key":"10.1016\/j.numecd.2025.103852_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232112906","article-title":"The role of inflammation in cardiovascular disease","volume":"23","author":"Henein","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"24","key":"10.1016\/j.numecd.2025.103852_bib21","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1093\/eurheartj\/ehaa172","article-title":"Triglycerides and remnant cholesterol associated with risk of aortic valve stenosis: mendelian randomization in the Copenhagen General Population Study","volume":"41","author":"Kaltoft","year":"2020","journal-title":"Eur Heart J"},{"key":"10.1016\/j.numecd.2025.103852_bib22","article-title":"High remnant cholesterol level Potentiates the development of hypertension","volume":"13","author":"Chen","year":"2022","journal-title":"Front Endocrinol"},{"issue":"34","key":"10.1016\/j.numecd.2025.103852_bib23","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1093\/eurheartj\/ehab705","article-title":"Elevated remnant cholesterol increases the risk of peripheral artery disease, myocardial infarction, and ischaemic stroke: a cohort-based study","volume":"43","author":"Wadstr\u00f6m","year":"2022","journal-title":"Eur Heart J"},{"issue":"9","key":"10.1016\/j.numecd.2025.103852_bib24","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/j.amjcard.2017.01.033","article-title":"Relation of fasting triglyceride-rich lipoprotein cholesterol to coronary artery calcium score (from the ELSA-Brasil study)","volume":"119","author":"Bittencourt","year":"2017","journal-title":"Am J Cardiol"},{"issue":"9841","key":"10.1016\/j.numecd.2025.103852_bib25","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(12)60312-2","article-title":"Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study","volume":"380","author":"Voight","year":"2012","journal-title":"Lancet Lond Engl"},{"issue":"10","key":"10.1016\/j.numecd.2025.103852_bib26","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1177\/2047487319887578","article-title":"Remnant cholesterol, coronary atheroma progression and clinical events in statin-treated patients with coronary artery disease","volume":"27","author":"Elshazly","year":"2020","journal-title":"Eur J Prev Cardiol"},{"issue":"7","key":"10.1016\/j.numecd.2025.103852_bib27","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.122.014116","article-title":"Remnant cholesterol and the risk of coronary artery calcium progression: Insights from the CARDIA and MESA study","volume":"15","author":"Hao","year":"2022","journal-title":"Circ Cardiovasc Imaging"},{"issue":"5","key":"10.1016\/j.numecd.2025.103852_bib28","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.numecd.2023.02.009","article-title":"Remnant cholesterol as a risk factor for all-cause and cardiovascular mortality in incident peritoneal dialysis patients","volume":"33","author":"Deng","year":"2023","journal-title":"Nutr Metab Cardiovasc Dis NMCD"},{"issue":"2","key":"10.1016\/j.numecd.2025.103852_bib29","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/ehjcvp\/pvz079","article-title":"An expert opinion paper on statin adherence and implementation of new lipid-lowering medications by the ESC Working Group on Cardiovascular Pharmacotherapy: Barriers to be overcome","volume":"6","author":"Drexel","year":"2020","journal-title":"Eur Heart J Cardiovasc Pharmacother"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475325000067?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475325000067?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:38:21Z","timestamp":1762331901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475325000067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S0939475325000067"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2025.103852","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of remnant cholesterol with coronary heart disease and severity of coronary artery stenosis in non-dialysis patients with stage 3\u20135 chronic kidney disease","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2025.103852","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V. on behalf of The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University.","name":"copyright","label":"Copyright"}],"article-number":"103852"}}