{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:44:59Z","timestamp":1792525499601,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002923","name":"National Scientific and Technical Research Council","doi-asserted-by":"publisher","award":["PIP N\\u00B011220200102363"],"award-info":[{"award-number":["PIP N\\u00B011220200102363"]}],"id":[{"id":"10.13039\/501100002923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007351","name":"Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007351","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005363","name":"Universidad de Buenos Aires","doi-asserted-by":"publisher","award":["UBACyT N\\u00B020020190100075BA"],"award-info":[{"award-number":["UBACyT N\\u00B020020190100075BA"]}],"id":[{"id":"10.13039\/501100005363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","nmcd-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.numecd.2026.105011","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:46:41Z","timestamp":1790380001000},"page":"105011","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metabolically healthy obesity in children and adolescents: A misleading label?"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2039-214X","authenticated-orcid":false,"given":"Bel\u00e9n","family":"Davico","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8555-9174","authenticated-orcid":false,"given":"Maximiliano","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gaete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezequiel","family":"Lozano Chiappe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"G\u00f3mez Rosso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Luz","family":"Muzzio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Soledad","family":"Saez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Palenque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Osta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Puma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agustina","family":"Varela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Roussos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Gabriela","family":"Ballerini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Brites","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.numecd.2026.105011_bib1","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/ijo.2010.222","article-title":"Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review","volume":"35","author":"Reilly","year":"2011","journal-title":"Int J Obes"},{"issue":"5","key":"10.1016\/j.numecd.2026.105011_bib2","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/s41366-024-01710-4","article-title":"Association between early age body mass index and the risk of adulthood cardiovascular diseases: a systematic review and meta-analysis","volume":"49","author":"Qiu","year":"2025","journal-title":"Int J Obes"},{"issue":"11","key":"10.1016\/j.numecd.2026.105011_bib3","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1111\/obr.12721","article-title":"Defining metabolically healthy obesity in children: a scoping review","volume":"19","author":"Damanhoury","year":"2018","journal-title":"Obes Rev"},{"issue":"3","key":"10.1016\/j.numecd.2026.105011_bib4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000471488","article-title":"The metabolic phenotype in obesity: fat mass, body fat distribution, and adipose tissue function","volume":"10","author":"Goossens","year":"2017","journal-title":"Obes Facts"},{"issue":"5","key":"10.1016\/j.numecd.2026.105011_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13548","article-title":"Risk factors, cutoff points, and definition of metabolically healthy\/unhealthy obesity in children and adolescents: a scoping review of the literature","volume":"24","author":"Abiri","year":"2023","journal-title":"Obes Rev"},{"issue":"12","key":"10.1016\/j.numecd.2026.105011_bib6","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1016\/j.numecd.2023.08.019","article-title":"Impaired HDL-associated enzymes and proteins in children and adolescents with weight disorders and their association with novel cardiometabolic indexes","volume":"33","author":"Martin","year":"2023","journal-title":"Nutr Metabol Cardiovasc Dis"},{"issue":"4","key":"10.1016\/j.numecd.2026.105011_bib7","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1097\/MOP.0000000000000913","article-title":"Obesity and insulin resistance in children","volume":"32","author":"Tagi","year":"2020","journal-title":"Curr Opin Pediatr"},{"issue":"7","key":"10.1016\/j.numecd.2026.105011_bib8","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s12098-017-2504-0","article-title":"Cardiovascular and metabolic complications - diagnosis and management in Obese children","volume":"85","author":"Vikram","year":"2018","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.numecd.2026.105011_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/LPI.S10805","article-title":"Obesity and insulin resistance: an abridged molecular correlation","volume":"6","author":"Mukherjee","year":"2013","journal-title":"Lipid Insights"},{"issue":"5","key":"10.1016\/j.numecd.2026.105011_bib10","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s11883-016-0572-7","article-title":"Speciated high-density lipoprotein biogenesis and functionality","volume":"18","author":"Rosales","year":"2016","journal-title":"Curr Atheroscler Rep"},{"issue":"11","key":"10.1016\/j.numecd.2026.105011_bib11","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.32604\/biocell.2023.031063","article-title":"High density lipoprotein as a therapeutic target: focus on its functionality","volume":"47","author":"Gomez","year":"2023","journal-title":"Biocell"},{"issue":"10","key":"10.1016\/j.numecd.2026.105011_bib12","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/s41569-021-00538-z","article-title":"High-density lipoproteins, reverse cholesterol transport and atherogenesis","volume":"18","author":"Pownall","year":"2021","journal-title":"Nat Rev Cardiol"},{"issue":"1","key":"10.1016\/j.numecd.2026.105011_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s43044-024-00523-0","article-title":"Lecithin and cardiovascular health: a comprehensive review","volume":"76","author":"Onaolapo","year":"2024","journal-title":"Egypt Heart J"},{"issue":"1","key":"10.1016\/j.numecd.2026.105011_bib14","first-page":"27","article-title":"Insulin resistance in childhood obesity: the role of dietary habits and their association with novel markers of cardiovascular disease","volume":"18","author":"Davico","year":"2024","journal-title":"Med J Nutrition Metab"},{"key":"10.1016\/j.numecd.2026.105011_bib15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bbacli.2017.07.002","article-title":"Antioxidative activity of high-density lipoprotein (HDL): mechanistic insights into potential clinical benefit","volume":"8","author":"Brites","year":"2017","journal-title":"BBA Clin"},{"issue":"3","key":"10.1016\/j.numecd.2026.105011_bib16","doi-asserted-by":"crossref","first-page":"262","DOI":"10.12997\/jla.2024.13.3.262","article-title":"Emerging circulating biomarkers for enhanced cardiovascular risk prediction","volume":"13","author":"Lee","year":"2024","journal-title":"J Lipid Atheroscler"},{"issue":"1","key":"10.1016\/j.numecd.2026.105011_bib17","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.tjnut.2023.08.037","article-title":"Impaired reverse cholesterol transport is associated with changes in fatty acid profile in children and adolescents with abdominal obesity","volume":"154","author":"Martin","year":"2024","journal-title":"J Nutr"},{"issue":"1","key":"10.1016\/j.numecd.2026.105011_bib18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.numecd.2021.09.025","article-title":"Vascular inflammation and impaired reverse cholesterol transport and lipid metabolism in obese children and adolescents","volume":"32","author":"Martin","year":"2022","journal-title":"Nutr Metabol Cardiovasc Dis"},{"issue":"2","key":"10.1016\/j.numecd.2026.105011_bib19","doi-asserted-by":"crossref","first-page":"200","DOI":"10.12997\/jla.2025.14.2.200","article-title":"Fatty acids in childhood obesity: a link between nutrition, metabolic alterations and cardiovascular risk","volume":"14","author":"Davico","year":"2025","journal-title":"J Lipid Atheroscler"},{"key":"10.1016\/j.numecd.2026.105011_bib20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.nut.2018.08.017","article-title":"Prevalence of metabolically healthy obese phenotype and associated factors in South American overweight adolescents: a cross-sectional study","volume":"60","author":"Remor","year":"2019","journal-title":"Nutrition"},{"key":"10.1016\/j.numecd.2026.105011_bib21","unstructured":"https:\/\/www.who.int\/tools\/growth-reference-data-for-5to19-years\/indicators\/bmi-for-age."},{"issue":"24","key":"10.1016\/j.numecd.2026.105011_bib22","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.1016\/j.jacc.2018.11.003","article-title":"AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\/NLA\/PCNA guideline on the management of blood cholesterol: a report of the American college of cardiology\/american heart association task force on clinical practice guidelines","volume":"73","author":"Grundy","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.numecd.2026.105011_bib23","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0003-2697(89)90424-7","article-title":"Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase\/arylesterase","volume":"180","author":"Furlong","year":"1989","journal-title":"Anal Biochem"},{"issue":"10","key":"10.1016\/j.numecd.2026.105011_bib24","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1161\/01.ATV.16.10.1243","article-title":"Paraoxonase genotypes, lipoprotein lipase activity, and HDL","volume":"16","author":"Nevin","year":"1996","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.numecd.2026.105011_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2013.10.089","article-title":"Lecithin cholesterol acyltransferase (LCAT) activity in the presence of Apo-AI-derived peptides exposed to disorder-order conformational transitions","volume":"441","author":"Aguilar-Espinosa","year":"2013","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"10.1016\/j.numecd.2026.105011_bib26","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/0006-291X(83)91778-3","article-title":"Inactivation of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine by a plasma acetylhydrolase: higher activities in hypertensive rats","volume":"113","author":"Blank","year":"1983","journal-title":"Biochem Biophys Res Commun"},{"issue":"6","key":"10.1016\/j.numecd.2026.105011_bib27","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1161\/01.ATV.13.6.815","article-title":"Influence of plasma cholesteryl ester transfer activity on the LDL and HDL distribution profiles in normolipidemic subjects","volume":"13","author":"Lagrost","year":"1993","journal-title":"Arterioscler Thromb"},{"issue":"8","key":"10.1016\/j.numecd.2026.105011_bib28","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/S0022-2275(20)31582-0","article-title":"A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids","volume":"42","author":"Navab","year":"2001","journal-title":"J Lipid Res"},{"issue":"4","key":"10.1016\/j.numecd.2026.105011_bib29","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1097\/MOP.0000000000000913","article-title":"Obesity and insulin resistance in children","volume":"32","author":"Tagi","year":"2020","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.numecd.2026.105011_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1503704","article-title":"Research progress on the relationship between free fatty acid profile and type 2 diabetes complicated by coronary heart disease","volume":"15","author":"Liu","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.numecd.2026.105011_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1230051","article-title":"Systemic and local vascular inflammation and arterial reactive oxygen species generation in patients with advanced cardiovascular diseases","volume":"10","author":"Sulicka-Grodzicka","year":"2023","journal-title":"Front Cardiovasc Med"},{"issue":"11","key":"10.1016\/j.numecd.2026.105011_bib32","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1161\/ATVBAHA.108.169722","article-title":"Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance","volume":"28","author":"Kim","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"12A","key":"10.1016\/j.numecd.2026.105011_bib33","doi-asserted-by":"crossref","first-page":"51F","DOI":"10.1016\/j.amjcard.2008.04.019","article-title":"Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines","volume":"101","author":"Davidson","year":"2008","journal-title":"Am J Cardiol"},{"issue":"4","key":"10.1016\/j.numecd.2026.105011_bib34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s10557-021-07166-2","article-title":"Insulin rescued MCP-1-Suppressed cholesterol efflux to large HDL2 particles via ABCA1, ABCG1, SR-BI and PI3K\/Akt activation in adipocytes","volume":"36","author":"Sun","year":"2022","journal-title":"Cardiovasc Drugs Ther"},{"issue":"11","key":"10.1016\/j.numecd.2026.105011_bib35","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.5551\/jat.4721","article-title":"Insulin suppresses HDL-mediated cholesterol efflux from macrophages through inhibition of neutral cholesteryl ester hydrolase and ATP-binding cassette transporter G1 expressions","volume":"17","author":"Yamashita","year":"2010","journal-title":"J Atherosclerosis Thromb"},{"issue":"5","key":"10.1016\/j.numecd.2026.105011_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2025.100796","article-title":"HDL meets triglyceride","volume":"66","author":"Akcan","year":"2025","journal-title":"J Lipid Res"},{"issue":"4","key":"10.1016\/j.numecd.2026.105011_bib37","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1080\/10409238.2021.1925217","article-title":"Cholesterol efflux pathways, inflammation, and atherosclerosis","volume":"56","author":"Groenen","year":"2021","journal-title":"Crit Rev Biochem Mol Biol"},{"issue":"8","key":"10.1016\/j.numecd.2026.105011_bib38","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1194\/jlr.C061366","article-title":"SAA: a link between cholesterol efflux capacity and inflammation?","volume":"56","author":"Thomas","year":"2015","journal-title":"J Lipid Res"},{"key":"10.1016\/j.numecd.2026.105011_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/658913","article-title":"New insight into adiponectin role in obesity and obesity-related diseases","volume":"2014","author":"Nigro","year":"2014","journal-title":"Biomed Res Int"},{"issue":"12","key":"10.1016\/j.numecd.2026.105011_bib40","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/obr.12064","article-title":"Adiponectin and lipoprotein metabolism","volume":"14","author":"Christou","year":"2013","journal-title":"Obes Rev"},{"issue":"1","key":"10.1016\/j.numecd.2026.105011_bib41","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1161\/ATVBAHA.118.311366","article-title":"Cholesterol mass efflux capacity, incident cardiovascular disease, and progression of carotid plaque","volume":"39","author":"Shea","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"9","key":"10.1016\/j.numecd.2026.105011_bib42","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1161\/ATVBAHA.119.312645","article-title":"HDL (High-Density lipoprotein) cholesterol efflux capacity is associated with incident cardiovascular disease in the general population","volume":"39","author":"Ebtehaj","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5","key":"10.1016\/j.numecd.2026.105011_bib43","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1097\/MOL.0000000000000446","article-title":"Time to ditch HDL-C as a measure of HDL function?","volume":"28","author":"Ronsein","year":"2017","journal-title":"Curr Opin Lipidol"},{"issue":"25","key":"10.1016\/j.numecd.2026.105011_bib44","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1161\/CIRCULATIONAHA.116.025678","article-title":"Cholesterol efflux capacity, high-density lipoprotein particle number, and incident cardiovascular events: an analysis from the JUPITER trial (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin)","volume":"135","author":"Khera","year":"2017","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.numecd.2026.105011_bib45","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1530\/EJE-21-0743","article-title":"China Kadoorie Biobank (CKB) collaborative group. Metabolically healthy obesity, transition to unhealthy phenotypes, and type 2 diabetes in 0.5 million Chinese adults: the China Kadoorie Biobank","volume":"186","author":"Song","year":"2022","journal-title":"Eur J Endocrinol"},{"issue":"3","key":"10.1016\/j.numecd.2026.105011_bib46","doi-asserted-by":"crossref","DOI":"10.1210\/endrev\/bnaa004","article-title":"Metabolically healthy obesity","volume":"41","author":"Bl\u00fcher","year":"2020","journal-title":"Endocr Rev"},{"issue":"3","key":"10.1016\/j.numecd.2026.105011_bib47","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41366-023-01425-y","article-title":"Conversions between metabolically unhealthy and healthy obesity from midlife to late-life","volume":"48","author":"Ler","year":"2024","journal-title":"Int J Obes"},{"key":"10.1016\/j.numecd.2026.105011_bib48","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3389\/fendo.2019.00865","article-title":"Children with metabolically healthy obesity: a review","volume":"10","author":"Vukovic","year":"2019","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Nutrition, Metabolism and Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475326004734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939475326004734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:26:35Z","timestamp":1792524395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939475326004734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":48,"alternative-id":["S0939475326004734"],"URL":"https:\/\/doi.org\/10.1016\/j.numecd.2026.105011","relation":{},"ISSN":["0939-4753"],"issn-type":[{"value":"0939-4753","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolically healthy obesity in children and adolescents: A misleading label?","name":"articletitle","label":"Article Title"},{"value":"Nutrition, Metabolism and Cardiovascular Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.numecd.2026.105011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105011"}}